Adipose Tissue
Adipocytes function
Energy storage, insulation, space filled as cushion
Major adipokines secreted by WAT
PGI2, PGF2 alpha, leptin, adiponectin, resistin, visfatin, apelin, angiotensinogen, AGA 2, Interlukins, bone morphogenic protien, fatty acids and estrogen
Master switch of regulation of WAT differentation
PPARy/ RXR
Master switch for BAT differention
PRDM/PGC-1
Two types of adipose tissue
White and brown adipose tissue
Adipose tissue
a specialized connective tissue that plays an important role in energy homeostasis and hormone production
Adipose tissue is an important part in?
energy homeostasis, adipogenesis, steroid metabolism, angiogenesis and immune response
White adipose tissue functions
energy storage, insulation, cushion for vital organs and secretion of hormones
Adipocytes
fat filled cells, ring shaped cells filled with triglycerides chicken wire appearance nucleus is pressed against cell membrane
Adipokines
hormone production
Brown Adipose tissue
multilocular
Brown adipose tissue
present in newborns mitochondira of brown fat cells express uncoupling protein which short curcuits the ETC producing heat instead of ATP
Subcutaneous fasicia
provides a significant thermal insulation against cold by reducing the rate of heat loss
WAT stucture
spherical but looks oval shaped when a lot supplied with blood vessels and capillaries
Adipocytes location
subcutaneous fat beneath skin, breast, heart surface, surrounds organs, joints, eyeball and is with the abdomen.
White adipose tissue
unilocular