Altius All
What is gluconeogenesis? Steps?
Reverse of glycolysis Produces glucose from pyruvate Occurs in the liver when fasting and is done when there is a need to increase blood sugar 1. Pyruvate is converted to oxaloacetate by pyruvate carboxylase 2. Oxaloacetate is converted to phosphoenolpyruvate by phosphoenolpyruvate carboxykinase 9. Fructose 1,6 Bis-P is converted to Fructose 6 Phosphate by Fructose 1,6 Bisphosphatase 11. Glucose 6 Phosphate is converted to glucose by Glucose 6 Phosphatase (all other steps are the same, except 1 is added and 2, 9, and 11 have different enzymes)
Describe Michaelis-Menten kinetics and graph Km, Vmax, and V
Saturation Kinetics Graphs the reaction velocity (y) vs substrate concentration (x) Vmax: is the rate of the reaction at saturation of substrate. Theoretical but never really achieves this velocity. Km: Michaelis constant. Is the substrate concentration at 1/2Vmax. A lower Km means a stronger binding affinity v= Vmax [S] ÷ Km + [S]
Schwann cells vs oligodendrocytes
Schwann cells myelinate axons in the PNS. Their bodies wrap around the axon Oligodendrocytes myelinate axons in the CNS. Secrete the myelin sheath around the axon
What is functionalism?
See's society as a complex system made up of interdependent institutions that work together to promote the status quo. Any change is seen as dysfunctional Members of society have reached a general consensus on what is right and wrong, bad and good
Selection bias vs observer bias
Selection bias-method used to select the participants is not truly random Observer bias-observers know the goals/hypothesis and allow knowledge to influence their observations
Simple vs Conjugated proteins
Simple= protein that contains only amino acids and no non-protein cofactors or prosthetic groups Conjugated= protein that is associated with it's cofactors, either covalently or intermolecularly (hemoglobin, has a non-protein heme group)
Single-blind vs Double-blind study
Single-information about the purpose of the study, control groups, or treatment is concealed from experimenters or subjects; but NOT both Double-information is concealed from both experimenters and subjects
Electrical pathway in heart
Sinoatrial node (SA node) starts --> Atrioventricular node (AV node), slight delay --> down the bundle of His --> Purkinje fibers --> cell to cell through gap junctions
Describe the propagation through 3 different macro mediums
Solid>liquid>gas
Acetylcholinesterase: describe and what an agonist and antagonist would do
Specialized enzyme in the synaptic cleft that breaks down acetylcholine to interrupt it's action Antagonist: (inhibitor) would impeded the ability to break down acetylcholine, ending up with more acetylcholine and hyperstimulation of neurons Agonist: (activator) would assist in the breakdown of acetylcholine and would result in decreased stimulation of neurons (Antagonists can help to combat depression: fluoxetine, sertraline, amitriptyline)
Describe STP
Standard temperature and pressure the conditions for ideal gases P=1 atm; V= 22.4L; n=1 mole; R=0.0821 or 8.314; T=273K (0°C) *NOT the same as Standard Conditions*
Where does CO₂ leave the citric acid cycle?
Step 3 and step 4 (conversion of isocitrate to α-ketoglutarate and conversion of α-ketoglutarate to succinyl CoA)
What is glycogenolysis? Where?
Stimulated by glucagon. Breaks down glycogen stored in the liver to form free glucose for release into the blood
What is labeling theory of deviance
Symbolic interactionists. Deviance and conformity result from how others respond to another person's actions. Deviance is relative
What is gluconeogenesis and where does it occur?
Synthesis of glucose from non-carbohydrate substrates. Primarily in the liver.
What are the 3 kinds of lymphocytes
T cells, B cells, and natural killer cells
Parietal lobe is responsible for
Taste Body awareness Touch and pressure
What is terrorism in relation to globalization
Terrorism may also be exacerbated by globalization as technology increases and puts images of western modernization in the face of traditional muslim societies that find them offensive. Technology is part of globalization and is often used by terrorists for recruitment and radicalization.
What is the 85+ cohort and why is it relevant
The 85+ cohort is dramatically increasing in today's society. Because this was formerly though of as the end-of-life for most individuals, this creates new challenges regarding caring for elderly, strains on the healthcare system, and so forth
How will light bend going through from 1.0 index of refraction to 1.5
The best way to think about this is a car hitting a guard rail. Once it hits that more dense area, it will alter it's front end and bend at a more stiff angle upwards
What is energy (macro term); units
The capacity to do work Kinetic, Gravitational potential energy, elastic potential, electrical potential, potential energy stored by capacitor Units: N*m (Joules)
What is the proton motive force
The driving force of electrochemical gradient established by ETC that is harvested by ATP synthase to produce ATP Energy is released as protons move down their concentration gradient and down their electrical gradient toward mitochondrial matrix is used by ATP synthase to add free organic phosphate to ADP →ATP
What does a heating curve show? Where is ∆Hfusion and ∆Hvaporization? What will a phase change for water look like on this?
The phase changes are flat because to change between states requires energy. ∆Hfusion=change in x axis (flat part) during change from solid to liquid ∆Hvaporization= change in x axis (flat part) during change from liquid to gas A phase change for water, the solid to liquid will be shorter than liquid to gas change because going to gas requires of the intermolecular H bonds to be broken
Why is ATP such an energetically favorable storage molecule
The phoshoanhydride bonds are highly energetic. At physiological pH, the phosphate groups lose their protons and become negatively charged. With three negatively charged groups attached, there is a lot of repulsion. Also ADP and Pi are much more stable than ATP
Describe the charge distribution in a battery
The positive pole doesn't have more positrons, it just has a lack of electrons (cation). The negative pole has an excess of electrons (anion)
What is elastic potential energy? Equation?
The potential energy store in a compressed spring PE=1/2k∆x²
Describe what the baby boomer cohort is and why its relevant
This cohort was created by a large increase in the number of births immediately following WWII. Baby boomers began retiring in approximately 2010 and will continue at a rate of a quarter-million people per month for the next two decades. This will have a dramatic impact on social security, the healthcare system, and the US economy and many other social institutions
Differential association theory of deviance
Through interactions with other, individuals learn values, attitudes, and techniques for deviant behavior, especially criminal
Where are lanthanides on periodic table
Top row of bottom
Totipotent vs pluripotent vs multipotent
Totipotent= cells can give rise to all of the cell types in body, including extraembryological or placental cells. Embryonic cells within first few cell divisions after fertilization are the only totipotent cells Pluripotent= cells can give rise to all of cell types that make up the body, but not extraembryonic cells. Undifferentiated embryonic cells=pluri Multipotent= cells can develop into more than one cell type, but are further differentiated and more limited than pluripotent cells. Adult stem cells and cord blood stem cells are multi
Describe how to form acid chlorides
Treat a carboxylic acid with PCl3, PCl5, or SOCl2. Will not work with just Cl-
What is a phase diagram? Describe what the triple point is. Critical point?
Triple point= temperature and pressure at which all 3 phases exist simultaneously in equilibrium with each other Critical point= temperature and pressure above which liquid and gas become indistinguishable. They are now called a Supercritical Fluid
What are the digestive enzymes that the pancreas secretes? What do each do?
Trypsin and chymotrypsin: proteases that cleave peptide bonds at specific AA sequences Pancreatic amylase: catalyzes hydrolysis of carbohydrates Lipase: catalyzes hydrolysis of fats Ribonuclease and deoxyribonuclease: catalyze hydrolysis of RNA and DNA
What is Type I vs Type II Error?
Type I: researchers claimed difference between groups when non existed. False positive-rejected null hypothesis but shouldn't have Type II: researchers didn't claim difference when it existed. False negative- should have rejected null hypothesis but didn't
What are riots
Undirected, highly emotional social eruptions that result in violence. Typically in response to social injustice
What is the Hardy-Weinberg equation?
Used for estimation of allele frequency. p²+2pq+q²=1 p+q=1 p=dominant q=recessive pq=hetero
What is Hooke's Law
Used for springs F=k∆x (∆x=displacement of spring from equilibrium point)
Describe affinity chromatography
Used to isolate specific molecules based on very specific affinity or bonding interactions
What is intersectionality?
Various forms or systems of oppression, domination, or discrimination interacting with one another to create a new form of oppression or experience that cannot be understood by considering each concept individually (a black female experiences more)
Calculate average velocity
Vavg=(V₁ + V₂)/2
Difference between vectors and scalars
Vectors have both a magnitude and direction Scalars have only a magnitude Vectors=velocity, displacement, acceleration, force, energy Scalars=mass, temp, speed, work
Difference between velocity and speed
Velocity=rate of change of displacement Speed= rate of change of distance They will only be the same if distance traveling is along a straight line
Vertical vs horizontal social mobility
Vertical= a change in social status or class (poor individual marries into a rich family) Horizontal= a change in position within a class that does not result in a change in social status (e.g. a working class man gets a job with a small pay raise; the job comes with no new status or significant increase in wealth)
Describe the starvation state
Very high glucagon and epinephrine levels Very high rate of gluconeogenesis High rate of fatty acid oxidation, resulting in ketone bodies and acidosis
Describe the pinacol rearrangement
Vic-diol + hot acid --> ketone or aldehyde The two hydroxyls must be in vicinal positions and carbons must be tri or tetra substituted (tri=aldehdye, tetra=ketone)
What are the villi in the small intestine?
Villi are finger like projections on the wall of the small intestine. They are hollow and contain blood vessels and a single lymphatic vessel called a lacteal.
Define work and ways to get work
W=∆Energy -Change in velocity (change in KE) -Change in height (change in PE) -Change in position of masses/planets (gravitational PE) -Change in position of charge (Electric PE) -Compression of spring (elastic PE) -Friction (change in internal energy) -Air resistance (change in internal energy)
Characteristics of tight junctions (ex of where found)
Water-proof barriers Found on the epidermis of the skin
What is privilege (social class)
When groups of people have advantages compared to other groups. Can be financial or emotional. Exists in race, ethnicity, gender, age, sexual orientation, disability, and social class
How does UV spectroscopy work? What do they expose?
When molecules that are exposed to UV radiation, electrons within that molecule absorb energy and excite to the next highest energy level. There will be a peak at absorbance when the wavelength matches the energy emitted Will expose double and triple bonds, and conjugated systems will absorb UV more strongly than isolated double or triple. A greater conjugation will have a further right shift (greater wavelength)
What is a racemic mixture
a 50/50 mixture of two enantiomers (R and S) Optically inactive (two planes cancel)
What is a fatty acid
a carboxylic acid with long, even numbered chains from 4 to 28 Carbons long
Centrioles vs Centrosomes (functions and characteristics)
a centrosome is an amorphous area of proteins and nucleating factors within which the centrioles are located (2 centrioles within a centrosome). They organize microtubules, flagella and cilia. Play a key role in cell division
What is a demographic shift
a change in the makeup of a population over time as measured by demographic factors such as age, population size, diversity, etc
What is an anhydrous compound
a compound that contains no water but can form complexes with water
Who is Carl Jung? How did he differ?
a contemporary and supporter of Freud, who later developed his own psychoanalytical theory
What is an action potential
a disturbance in resting electrical potential across membrane of a nerve cell Once created, will propagate along cell membrane to neighboring portions of the neurons. As it does, areas where it originally started will gradually return to normal
Describe the Lineweaver-Burk Plot
a double inverse of the reaction rate and substrate concentration (from MM graph) Y intercept= 1/vmax X intercept= -1/Km Slope= Km/vmax Used to identify enzyme inhibition experimentally (with 2 trials; 1 w/ and 1 w/o)
What is gender inequality?
a general term describing any aspect of society wherein individuals are treated differently based upon gender
Describe a G-protein/response
a hormone/signaling molecule binds to integral protein on extracellular domain (protein is called GPCR) This causes conformational change that activates cytosolic domain of GPCR. In the cytosolic domain, there is a G protein made of an alpha, beta, and gamma subunit. The alpha binds GTP and GDP (GTP bound="on"; GDP bound= "off"). The alpha subunit separates from b and gamma, and alpha acts as agonist for adenylyl cyclase which catalyzes conversion of ATP to cAMP plus 2 inorganic phosphates.
Describe what gel electrophoresis is
a lab technique used to separate molecules by size. The smallest molecules will travel the furthest
Describe self-esteem
a person's overall sense of self-worth or personal value. This is relatively stable and enduring. Is a valuation judgement of one's worth; "My Value"
Describe what gravity filtration is
a physical separation of solid from a liquid by passing it through filtration paper (often fluted paper) the only difference between this and vacuum filtration is the lack of a vacuum being used
What is a monarchy?
a political system in which a single family rules from generation to generation. There are 26 monarchies in the world today, all of European monarchies are constitutional monarchies
What is authoritarianism?
a political system that denies the people participation in government. Controls the lives of people and there is no freedom of speech. Iran
What is prejudice
a preconceived belief or judgment about a person or group developed prior to, or not based upon, actual experience or knowledge. this is an attitude emotion can exacerbate prejudice (fear or anger) and inhibit reasoned judgement
Define sleep. Hormone response during sleep?
a regular state of rest and reduced consciousness deemed physiologically necessary at approximately 24 hour intervals (Circadian Rhythms) -Cortisol levels are higher when awake/alert than during sleep. -Melatonin is released by pineal gland in part to decreasing levels of light
What is a concentration cell
a special kind of galvanic cell the same electrodes and solution are used in both beakers E0 of cell= 0V under standard conditions, driven by different concentrations and use the Nernst equation
A strong oxidizing agent would effect reduction potential how
a strong oxidizing agent would have high reduction potential
What is a non-reducing sugar?
a sugar that cannot participate in redox reaction to reduce another molecule. No aldehyde group
Role of bases in organic reactions
abstract protons (Hydrogens) are electron dense and have full or partial negative charges
Semantic Networks (explanation)
adding context and meaning to what would otherwise be rote fuel. LTMs are a web-like network of concepts, and this creates a connection, with the strength of the connection being inversely proportional to the length of the connection
What is the common ion effect?
addition of a common ion will cause a precipitant
Epinephrine and norepinephrine: location, class, function
adrenal medulla tyrosine derivative/water-soluble cause responses to almost identical sympathetic nervous system response (fight or flight)
Describe gentrification and urban renewal
after an urban area has decline, demand for real estate from buyers wanting to live in the city leads to revitalization projects that convert less-desirable urban areas into high-rent urban apartments and shopping areas. The process is called gentrification because although the area is revitalized, only the wealthy can afford to live there
What is alternative splicing
after introns are removed from mRNA transcript, exons can be assembled in any number of different orders; with each variation resulting in a different protein.
Describe alcohol acidity
alcohol is less acidic than water acidity increases in alcohols from tertiary to secondary to primary
What are the states of consciousness
alertness, sleep, dreaming, hypnosis, mediation, and drug-altered
Where is DNA located
all DNA is located in the nucleus there is a small amount of non-nuclear DNA found in the mitochondria
Describe the role of bone marrow in immune system
all erythrocytes and leukocytes are made in bone marrow via hematopoiesis. Yellow bone marrow is primarily adipose tissue and does not produce blood cells B-lymphocytes mature in bone marrow, while T-lymphocytes migrate to thymus to mature
What is limited expressivity
all individuals have the same genotype AND all have the disease phenotype (100% penetrance), but individuals are impacted to varying degrees
What is an allosteric enzyme? Allosteric regulation?
allosteric enzymes change conformation and or affinity for their substrate upon binding of an allosteric regulator molecule allosteric regulation almost always results in conformational changes, always bind away from active site, and the effect is a change in the enzyme itself
Describe keto-enol tautomerization
alpha H adjacent to aldehyde or ketone becomes bonded to carbonyl oxygen, while double bond is switched from C=O to C=C The Ketone form is more favorable at RT
Describe olfactory cells
also called chemoreceptors. Triggered by membrane receptors that directly bind specific gaseous/vaporized airborne chemicals
Effects that air resistance has
always assume air resistance is being ignored unless specifically stated otherwise 1. ↑Cross-sectional area=↑air resistance 2. Less aerodynamic shape=more air resistance 3. ↑Velocity=↑Air resistance
Characteristics of a magnet
always come in dipoles, whereas in electrostatics you can just have a positive charge or a negative charge If you cut a magnet in half, each of these halves will reorient themselves into dipoles On a compass, the arrow will point "north" even though it's south because the arrow aligns itself with the field (moving from north to south)
What are retroviruses?
always contain RNA, therefore contain reverse transcriptase enzyme capable of translating RNA nucleotide sequence into DNA
What is Gibbs Free Energy, measurement, and value indications Equations for Gibbs Free Energy
amount of "free" or "useful" energy available to do work ∆G; measured in J Negative ∆G=spontaneous process, free energy available to do work Positive ∆G=non-spontaneous process, no free energy available, so energy is required ∆G=∆H-T∆S ∆G°=-RTlnKeq
Describe current
amount of charge "flowing" per unit time Amps=Q/t Current is denoted to flow from positive to negative in a circuit, even though electrons actually flow from negative to positive
What is heat of combustion
amount of energy released when a molecule is combusted with oxygen all covalent bonds are broken and reformed in radical reaction High energy of molecule= high heat of combustion
Function and characteristics of cholesterol (in reference to plasma membrane)
amphipathic molecule with a steroid region and a polar region. Inserted between phospholipids at very high concentrations in eukaryotic cells Adds rigidity and fluidity to the membrane
What are personality disorders?
an enduring pattern of personal experience and behavior that deviates noticeably from the expectations of one's culture, is pervasive and inflexible, has an onset in adolescence or early adulthood, is stable over time, and leads to personal distress or impairment
Describe meditation
an intentionally altered state of consciousness intended to improve focus or overall well-being. Part of many religious beliefs Not very well defined scientifically, but has been associated with a relaxed, slower wave state of arousal reproducible on an EEG
What is an electric field What do electric field lines do
an invisible influence that can exert a force on a mass or charge Field lines are drawn with tails at positive charge pointing away or toward the negative charge. Closer lines=stronger field
What is a specific phobia
an irrational and excessive fear of an object or situation. May be accompanied by dizziness, nausea, difficulty breathing, a sense of unreality, or a fear of dying. In extreme cases, it can induce a full scale panic attack
What is an ether, naming, IUPAC naming
an oxygen bonded to 2 R groups named with two R group and "ether" (methyl ethyl ether, diethylether) IUPAC: longer of two R groups is parent and other is substituent with suffix -oxy (1-ethoxyheptane)
What is fermentation
anaerobic glycolysis. This is the sole route of metabolizing glucose for most bacteria. Also used by animals only during oxygen debt and in ERYTHROCYTES
Analyte vs titrant
analyte=already in the beaker titrant=species being added dropwise for titration
How does animal breeding relate to genetically based behavior variation
animals can be bred to exhibit target behaviors, such as aggression being genetically-selected for in rodeo bulls, or hunting skills being genetically-selected in certain dog breeds
What are amines, naming, and bonding characteristics
any compound that contains a basic nitrogen atom Named by adding -amine to end (butanamine). If secondary or tertiary add N- and the shorter (N-ethylbutanamine or N-methyl-N-methylbutanamine) Primary and secondary act as nucleophiles, tertiary act as bases (too sterically hindered) Capable of H-bonding, but not as strong as alcohols Protein synthesis is the most common human body example of an amine acting as a nucleophile
What is epigenetics?
any heritable phenotype resulting from any process other than changing the DNA sequence itself
What is the iron law of oligarchy?
any large organization would develop a system of governance in which many people would come under the control of a few
What is Archimedes' Principle?
any object displaces an amount of fluid exactly equal to it's own volume, or the volume of whatever fraction of object that is submerged
What is patriarchy
any societal, political, cultural, or familial structure wherein men are thought to have greater power, authority, privilege, or rights than women. Historically it used to refer to family structure in which the father was thought of as the head of the household
What are cofactors
any species required by an enzyme to function (coenzymes or prosthetic groups)
Describe simple harmonic motion
anything that oscillates back and forth, represented by a sine wave graphically. T=2π√m/k (mass on a spring) T=2π√L/g (pendelum) T=period (inverse frequency)
What are glucocorticoids? Their effects?
are cortisol produced by adrenal cortex in response to ACTH from anterior pituitary They have a "glucagon-like effect on metabolism" in that they stimulate gluconeogenesis, glycogenolysis, and fatty-acid oxidation They also reduce inflammation
What is the spindle apparatus
array of microtubules that grows outwards from centrioles during mitosis to bind with centromere of chromosome during metaphase
Describe turbulence
at high speeds; although net flow is still in one direction, there are random eddies, changes in direction, velocity, etc
What is a leaving group
atoms that leave parent during reaction and take both electrons from the bond with them best leaving group=most stable after they leave
Electron donating/withdrawing in reactions
atoms with full/partial POSITIVE charges WITHDRAW from whatever they're attached to atoms with full/partial NEGATIVE charges DONATE to whatever they're attached to
What is the octet rule and what are the exceptions
atoms with low atomic numbers (<20) tend to gain or lose electrons to obtain exactly 8 electrons in valence shell (noble gas configuration) Exceptions: hydrogen and helium are stable with 2 Boron and Beryllium are stable with 6 (BF3) Atoms from 3rd period or higher can accept more than 8 (PCl5, SF6)
What is social cognitive theory of attitude change?
attitudes change because of observational learning. Not only about modeling, but looks at how observation, personal factors, and environment interact with one another to produce learning
Describe bacterial growth
bacterial colonies grow exponentially, doubling each generation. However, there is a limit to colony size as food resources decrease and waste accumulates
Describe the reactivity of alcohols
behave as either nucleophiles (lone pair on the oxygen acts as a lewis base) or as lewis acid when oxidized to carbonyl groups (oxygen accepts pair of electrons from the O-H bond as proton is abstracted)
Define reaction formation
behaving in ways that are in direct contradiction to one's true feelings Example would be a homosexual politician who actively pursues legislation to limit rights of homosexuals
What is altruism
behavior by an individual or group that benefits another individual or group at it's own expense Can still be selfish (i sacrifice now, but i get recognition or prestige)
What is aggression. Where is it associated in the brain
behavior intended to injure, harm, intimidate, or inflict pain on another. Threats prior to attack are common in humans and animals. Males are more aggressive than females because of testosterone. Caused by competition for food, resources, and reproduction Associated most closely with the hypothalamus and amygdala
What is the incentive theory of motivation
behavior is motivated by desire to obtain rewards or avoid punishment
What is the cognitive theory of emotion
behavior is motivated by thinking; including plans, goals, expectations, perceptions, and attributions Intrinsic motivation: purpose or drive is based on personal, internal, often unseen motives Extrinsic motivation: purpose or drive is based on external reward or stimuli
What are species-specific behaviors?
behavior observed only among members of the same species
What is familial concordance (in terms of genetically-based behavior variation)
behaviors shown to run in families or be more frequent among children of parents with that behavioral trait
Who is B.F. Skinner and what did he do?
best know for work on operant conditioning. Said that environment and reinforcement leads to behavior.
Bond length vs bond energy
bong length=distance between nuclei of atoms forming the bond Bond energy=amount of energy required to break a bond (same as bond strength). Stable molecules have high bond energy. If something is a "high energy molecule" molecule, then it has low bond energy
Describe coordinate covalent bonds
both the electrons in a covalent bond are donated by one atom
Where are actinides on periodic table
bottom row of bottom
What is reflection
bouncing of a wave off of an interface between two mediums
Define respiration in terms of carbohydrate metabolism What would aerobic vs anaerobic mean
breakdown of macromolecules into smaller pieces to harvest energy in the form of ATP aerobic=oxygen is the final electron acceptor anaerobic=molecule other than oxygen is final electron acceptor
Describe social-cognitive theory
broad psychological perspective that attempts to explain behavior, learning, and other phenomena includes observational learning, self-efficacy, situational influences, and cognitive processes Originally proposed by Albert Bandura
Describe the optic nerve
bundle of two separate fibers, one carrying information for left-half of visual field, one for the right half of the same visual field
What is dispersion
change in index of refraction based on frequency (or wavelength) Different frequencies/wavelengths are refracted at different angles Best example is white light through a prism
Habituation
changes in the level of one's attention. At a party with loud music and you barely notice it while talking to a friend because you shift your focus away from the music
What is somatic symptom disorder (SSD)?
characterized by physical symptoms of illness or injury that cannot be explained by a general medical condition or another mental disorder. Individuals often feel severe anxiety or distress about their undiagnosed condition and are preoccupied with its symptoms. The problem is not being fabricated by the patient, but is perceived by them as real
What is taste and what is the taste pathway
chemoreceptors on the tongue bind dissolved chemicals or ions Pathway: taste buds --> brain stem --> taste center in thalamus
What is an avoidant attachment childhood like and what are adults like
childhood: caregiver is absent or unresponsive to needs. Shows no preference to caregiver over strangers. Avoids their caregiver especially after a period of absence. Doesn't seek attention or comfort from caregiver adults: have problems dealing with intimate relationships. Don't invest emotionally in relationships and are unwilling to share feelings. Common to have promiscuous sexual relations
What is disorganized attachment childhood like and what are adults like
childhood: inconsistent caregiver, erratic, or abusive. Child displays a mix of unclear attachment behaviors. Often appears confused or dazed in presence of a caregiver. May assume role of caregiver at an early age adults: various negative social outcomes in avoidant or ambivalent disorders
Describe narcolepsy. Symptoms associated
chronic neurological disorder caused by autoimmune attack of the neurons that regulates hypocretin-the hormone that regulates the sleep wake cycle Sx include cataplexy and inappropriate daytime sleepiness. Will feel same tiredness all the time as normal adults after 24-48 hours. REM is entered after 5 minutes, while normal individuals enter REM after 90-120 minutes
Describe pitch of a sound
closely related to frequency an increased pitch sound has an increased frequency; decreased pitch=decreased frequency
Describe ion-exchange chromatography
column or stationary phase is coated with cations or anions. The mixture is passed through and oppositely charged ions adhere to the column Target molecules can be eluted by washing with a salt solution
Signal detection theory
combines sensory processing and decision making decides whether or not a stimulus or "signal" is present
Describe nervous system signaling
communication between two cells via electrical potential carried on neurons neurotransmitters bind to receptors on post-synaptic membrane which initiates a signaling cascade
Development effect on plasticity (describe) and what synaptic pruning does
compared to adult brains, infant brains contain approximately the same number of neurons, more synapses, and fewer glial cells Synaptic pruning: number of synapses is decreased through selective destruction of some synapses and strengthening of others. Weakest/least-frequently used are pruned while the strongest/most frequently used are strengthened
What is emotion
complex psychological state of mind involving one's mood, feelings, and reactions to circumstances
What is condosity
concentration of sodium chloride solution that will conduct electricity as well as the solution in question
Cones vs Rods in the human eye (characteristics)
cones=less sensitive than rods; perceive color, fine resolution of detail, and contain 3 pigments. They are located only in the fovea. Rods=highly sensitive. Perceive black and white only, have poor resolution of details. They contain only one pigment (rhodopsin). The relative number of rods=20X
What is belief perseverance
confronted with evidence that clearly contradicts our previously held belief, yet continue to hold onto it
Describe what is a buffer
contains a weak acid and weak base, often conjugates of each other resists changes in pH following the addition of acid or base the nearly horizontal area surrounding the half-equivalence point= "buffer region"
Function and characteristics of the rough ER
covered with ribosomes that actively translocates proteins into the ER lumen makes all proteins that are in the ER, golgi, lysosomes, endosomes, plasma membrane, or that are secreted out of the cell Post-translational modifications (disulfide bonds, glycosylations, etc.) are started here; continue in the golgi
Where is epithelial tissue found
covers the body of lines it's cavities epidermis of skin, endothelium of blood and lymph vessels, and mesothelium of thoracic cavity
Memory construction
creation, fabrication, or recall of FALSE memories
What is culture's role in attribution
culture impacts the kind of attributions one is likely to make. If a culture causes members to consider neighboring societies as enemies, then they will view their behaviors as negative and dispositional
What are the biological markers of depression
decreased monoamine levels in the brain (serotonin, dopamine, and norepinephrine). Increased cortisol level and glucose metabolism in the amygdala. The hippocampus of chronically-depressed patients atrophies (shrinks) compared to healthy individuals. Having a family member with depression is a risk factor
What is electrical potentials (E°), what are the units? What do positive and negative values indicate?
degree to which a species "wants electrons", or "wants to be reduced" Given in volts and represents half-reactions. Commonly shown for aqueous metals being reduced to their solid states (shown). All these values are compared to the hydrogen half cell reaction Positive E= More likely to gain electrons than hydrogen ions Negative E= less likely to gain electrons than hydrogen ions
What is self-identity
descriptive characteristics, qualities, and abilities that people use to define themselves "How i define myself; my idea of who i am"
What is sensation
detection of environmental stimuli by sensory receptors, conversion of those stimuli to an electrical impulse, and transmission of that impulse to the CNS
Function of juxtaglomerular apparatus
detects decreased blood pressure in afferent arteriole and then secretes Renin. This then sets into motion the Renin-Angiotensin pathway that increases blood volume and blood pressure
What is a calorimeter
device used to detect enthalpy changes (∆H) q=∆H for constant pressures
What is an epimer
diastereomers that differ at only one chiral center Many pairs of carbohydrates (glucose vs galactose)
Describe lipid absorption
digestion begins in the duodenum (SI) and is complete by the end of the small intestine. Cannot begin prior to small intestine because they will encounter bile and lipase in the SI Triacylglycerides are broken down into fatty acids, transported across membrane, and then reformed into triacylglycerides They will enter lacteals (Not blood stream). In order to travel, they must either bind to carrier proteins or be formed into a chylomicron or micelle
Describe carbohydrate absorption
digestion will begin in the mouth (from salivary amylase), and is complete by the time that food is passed through the small intestine Carbohydrates are broken down entirely to monomers (glucose, fructose, etc.) before absorption They will enter the blood stream and travel to the liver via hepatic portal vein
Characteristics of sigma bonds and what it looks like
directional head to head overlap of two orbitals Allow rotation, stronger, more stable, less reactive (than pi)
What is dispositional attribution vs situational attribution?
dispositional=explaining a behavior based on an individual's personality or disposition situational=explain a behavior as a function of context and circumstances in which behavior occurred.
What is paranoid personality disorder? What cluster is it a part of?
disruptive patterns of thought, behavior, and functioning. May be accompanied by pervasive distrust or suspicion, a feeling one is being lied to or exploited, a belief that friends and family are untrustworthy or unfaithful, attributing hidden meaning to everyday gestures and conversations Cluster A
Describe schizoid personality disorder? What cluster is it a part of?
disruptive patterns of thought, behavior, and functioning. May be accompanied by severe detachment from others, little to no desire to form relationships, a sense of indifference to praise, affirmation, criticism, or rejection, etc. These individuals rarely participate in fun or pleasurable activities and are described by others as cold, uninterested, withdrawn, or aloof Cluster A
What is schizotypal personality disorder? What cluster is it a part of?
distorted patterns of thought, behavior, and functioning. May be accompanied by eccentric perceptions, thoughts, or behaviors, "magical thinking", reported ability to read minds or foretell the future, talking to oneself, difficulty forming relationships, severe social anxiety, etc Cluster A
Define displacement (Freud)
diverting unacceptable feelings onto someone or something other than their source
Mitochondrial genetic code
doesn't use the same genetic code to translate their DNA as the normal DNA/RNA process
What is the lysogenic cycle?
dormant cycle of virus during which time DNA is incorporated into host's genome but new viruses aren't being assembled This would be HIV infection without AIDS symptoms
Role of vas deferens
duct that connects each testicle with urethra. Begins at epididymis and leads up inside scrotum, into pelvic cavity, past seminal vesicles, through prostate gland, and empties into urethra
Describe what a battery is. What are the indications in a circuit diagram
electron pump that push electrons onto negative terminal of battery. Electron flow is around the circuit toward the positive terminal longer line is the positive terminal, shorter line is the negative terminal
Functions of the amygdala
emotions Part of the limbic system also plays a role in sexual activity and libido
What are tumor suppressor genes?
encode proteins that in their normal state negatively regulate proliferation require 2 recessive alleles to lose function
1st Law of Thermodynamics
energy can neither be created or destroyed Work done on the system is (+) and work done by the system is (-) Total energy of an isolated system is always constant. The energy change in a closed system is the heat absorbed by that system and any work done on the system by it's surroundings ∆E=q+w
∆H(fusion)
enthalpy value associated with phase change from liquid to solid; reverse process is called melting
∆H(combustion)
enthalpy value for combustion of O₂ to CO₂ and H₂O High heat of combustion=unstable compound Low heat of combustion=stable compound
What are restriction endonucleases
enzymes that cut DNA at specific, pre-determined sequences
Describe the mismatched repair system
enzymes that scan newly copied DNA and locate, excise and replace mismatched pairs that are missed by DNA polymerase
Characteristics of erythrocytes
essentially just sacks of hemoglobin. immature RBCs start out with a nucleus and organelles but mature RBCs have NO organelles Therefore they do not undergo mitosis because of the lacking of cellular machinery.
What is prodromal phase of schizophrenia
essentially the early onset of schizophrenia. Mild, non-psychotic symptoms begin to surface. Individual may begin to show disinterest in things that once brought them pleasure or may begin to isolate themselves from others
What is stereotyping
establishing overgeneralized beliefs and expectations of a given group that may or may not match reality
Hormones released by the gonads (characteristics)
estrogen (ovaries), progesteron (ovaries), and testosterone (testes) Are steroids and lipid-soluble
What is the function of the excretory system
excrete liquid and solute waste (excess water, salts, nitrogenous waste, etc.) maintains pH, osmolarity, and blood pressure primarily involves the kidneys
Blind spot in eye
exists in each eye where the optic nerve passes through the retina
Culture and socialization influences
expectations and norms of one's culture along with socialization processes to which one is subject, provides strong driving force during identity formation. Certain identities may be encouraged/discouraged by different cultures
Describe how external chemicals and radiation can damage DNA
exposed to radiation, neighboring pyrimidines react with each other to form covalent dimers. Chemicals can cause alkylation of functional groups on DNA base Carcinogens, often polycyclic compounds, that bind to DNA make it a bulky side group
What is a stigma
extreme dislike or negativity toward a person or group (or some characteristic of that person or group) based on perceived deviance from social norms
Mirror focal point equation
f=1/2r (negative for convex; positive for concave)
Difference between feminism and feminist theory
feminism is a movement feminist theory is an area of study that explores psychological or sociological explanations for discrimination, inequality, and objectification
What is conflict theory?
focuses on how power differentials are created and how these differentials contribute to the maintenance of social order Marx is the father of conflict theory
Posterior pituitary (location and function) Derived from where?
forebrain secretes antidiuretic hormone (ADH aka vasopressin) and oxytocin Pituitary gland is derived from the ectodermal layer, the posterior portion is derived from the diencephalon
Pineal gland (location and function)
forebrain secretes melatonin, regulates sleep, receives input from retina regarding circadian rhythm
Hippocampus (location and function)
forebrain (part of the limbic system) memory consolidation (short-term to longer term) and explicit emotional memory
Microfilament characteristic and function
form "thin filament" portion of the sarcomere Also plays a role in the cytoskeleton
Describe Gabriel synthesis
form primary amines from primary alkyl halides. Avoids side products of regular alkyl synthesis
Difference between formal and informal social control
formal=laws, sanctions, or regulations enforced by an authority figure, often government informal=socialization, or any means used to encourage adherence to societal norms and values for acceptable behavior
What is speciation
formation of a new species from an existing one through evolution
Intermediate filament characteristic and function
general class of several proteins that polymerizes to form filaments that are intermediate in diameter (microfilaments=small; microtubules=large)
Neuronal Plasticity What 3 events/processes is plasticity closely associated with
general term referring to the brain and its neurons ability to physically change in response to various stimuli for various reasons. Synapses, dendrites, and glial cells all change 3 events: Development, Memory storage, and CNS injury
What are age cohorts
generational segments of society that share a common characteristic or life experiences because of the time period in which they were born Baby boomers, Gen X, Millennials, etc
Oncogenes
genes that cause cancer by blocking the normal controls on cell reproduction are generally gain-of-function alleles and only require one bad copy
What are regulatory genes
genes that code for a substance that regulates the transcription of another gene (up or down, promotion or inhibition)
What is anchoring and adjustment heuristic
giving higher priority to very first piece of information received and/or framing subsequent information around it
Progesterone: location, class, function
gonads (ovaries) steroid/lipid-soluble stimulates growth and maintenance of uterus during pregnancy
What are electrolytes
good electrolytes dissociate 100% in water (strong acids or bases) Ionic compounds that are soluble in water are always good
What is ethnicity
groups of people according to culture, religion, language, or national origin
Mitochondria function and characteristics
has it's own circular DNA and variations to nuclear genetic code pH of intermembrane space is lower than the matrix because of the H+ gradient
What is social perception
how we perceive other individuals or groups, form impressions of them, and make judgements about them. This is often inaccurate due to various bias'
What is cultural capital
ideas and knowledge people draw upon as they engage in social life. Example would be being able to speak in public to the correct use of utensils when eating
0th Law of Thermodynamics
if object A is in thermal equilibrium with object B, and object B is in thermal equilibrium with object C, then A and C must be in equilibrium with each other
Function of descending loop of Henle
impermeable to salts, but very permeable to water. So water flows out of filtrate which concentrates the urine
Insulator vs conductor
in a conductor, electron in material that conductor is made of can move around freely, whereas electrons in an insulator are fixed and don't move insulators can partially conduct by shifting the nucleus, but not the electrons charges added in a conductor will move to the outside edge of the material Glass, wood, plastic=insulator Gold, copper, silver=conductor
What is an in-group vs out-group
in-group=social groups that members feel an affinity for, loyalty to, and respect for out-groups=social groups that individuals feel conflict or competition toward
Define denial (Freud)
inability to accept some reality. Denying something despite the fact that there is an abundance of information on the contrary
Electronegativity trends
increasing going up and to the right F has largest (4.0) and Fr has smallest (0.7)
What is the familiarity effect
increasing level of familiarity with the example increases recall or verification rate (this will vary based on individuals familiarity) "Dog is a mammal" vs "Aardvark is a mammal"
Describe the strains associated with cycloalkanes
increasing strain the further you move away from cyclohexane (perfect at 109.5) Large rings (10+ carbons) have enough freedom to approximate tetrahedral angle and are therefore more stable as carbon numbers increase (not as stable as 6 still) Bicyclic rings typically have more strain than monocyclic would
Describe Galton's theory of intelligence
individual heritable characteristics contribute to intelligence as much as any gene gene contributes to physical traits Pioneered the nature vs nurture debate with monozygotic/dizygotic twin study Strongly in favor of the nature component and a strong proponent of eugenics
What is spatial inequality? Residential segregation?
inequality in some variable between persons living in geographic locations Residential segregation is physical separation of individuals with different characteristics or backgrounds into different neighborhoods. This is usually according to race, ethnicity, or SES
What is infrasound vs ultrasound
infrasound=sound of a frequency that is too low to be perceived by human ear ultrasound=sound frequency that is too high to be perceived by human ear
Heredity influence on cognitive development
inheritance of genetic predispositions, such as autism or down syndrome
Describe an irreversible inhibitor and give an example
inhibitor binds to the enzyme irreversibly, rendering the enzyme non-functional. Inhibitor binds the active site in some way that so that substrate can't ever attach again Aspirin binds the active sites of cyclooxygenase 1 and 2 and irreversibly prevents their inflammatory response
Characteristics of unitary/single-unit smooth muscles?
innervated by a single neuron and contract simultaneously as a single group Most common smooth muscle unit, found in most organs, blood vessels, digestive tract
Characteristics of multi-unit smooth muscle?
innervated by multiple neurons and doesn't act as a single unit Allows for more precise control These are rare, found in larger vessels such as aorta and in the retina of the eye
What are minerals used for?
inorganic molecules necessary for bone formation, ion gradients, oxygen transport, muscle contraction, ATP processing, and production of stomach acid
What are thermogenin channels
inserts in the inner mitochondrial membrane that allows an alternative pathway for H+ ions in the gradient. Results in a decreased production of ATP
What are the carbohydrate metabolism hormones
insulin, glucagon, glucocorticoids, catecholamines, T3 and T4
Describe voltage-gated potassium channels
integral membrane proteins that respond to a change in membrane potential. Much higher threshold than that of sodium channel. Only react to a very large change in membrane potential caused by depolarization Just before maximum depolarization is reached, Na+ channels begin to close and K+ channels begin to open
Describe the Stanford-Binet Intelligence Scale
intelligence follow a normal distribution (Gaussian) Mean is 100 and standard deviation is 15 Tests linguistic and logical-mathematical intellect IQ=Mental age/chronological age *100
Describe the difference between internalization and identification
internalization=process by which an individual accepts, as his/her own, a set of norms established by people or groups influential to that individual identification=process of incorporating the characteristics of a parent or other influential person by adopting their appearance, attitude, and behavior (tend to identify with persons are emotionally attached to and whom they perceive to be most similar to)
Describe REM sleep
intervallic period of sleep denoted by rapid or random eye movement at heightened sense of alertness that is greater than any of the sleep stages occurs between other stages, with several points of REM happening throughout the night First REM period are shorter and longest is typically in the morning right before waking Most vivid dreams are thought to occur during REM
Characteristics of smooth muscle
involuntary, non-striated, one nucleus controls gut, viscera, blood vessels, etc Not arranged in sarcomeres, so does not contract via the sliding filament model (but does have a similar system)
Characteristics of cardiac muscle
involuntary, striated only one nucleus Contains sarcomeres and thus use the same sliding filament model as skeletal muscles Contain large amounts of myoglobin and large amount of mitochondria to prevent fatigue Connected by intercalated discs containing gap junctions (ions for action potential pass through) These DO continue to divide after differentiation
Define projection (Freud)
involves attributing your own unwanted thoughts/feelings to someone else Example would be a teacher who doesn't like a student would insist that the student doesn't like them
Tubulin characteristics (how does it relate to microtubules)
is a globular protein that polymerizes to form microtubules alpha and beta subunit form a heterodimer and is assembled into a protofilament. 13 protofilaments surround a hollow core to make microtubule.
Isobaric vs isothermal system
isobaric=constant pressure isothermal=constant temperature (no heat exchange)
What does one equivalent added for acid/base titration mean
it is the amount of acid/base necessary to produce/consume one mole of [H⁺] ions 2 equivalents would be needed for H₂SO₄
What is ethnocentrism
judging another culture based solely on the values of own culture
What is cultural relativism
judging another's culture by it's own standards Something weird in another country may be normal based on their culture
What is the 2nd quantum number
l: the angular momentum (azimuthal quantum number) gives the subshell or orbital values of s,p,d,f (0,1,2,3 resp)
Describe the interactionist theory of language
language acquisition occurs in predictable fixed stages of development
Long-term memory and the 5 different types
lasting retention of information and skills; lasts a few minutes to a lifetime Procedural, episodic, explicit, implicit, and semantic
What is attitude
learned tendency to evaluate things in a certain way. Can be positive, negative, biased, or neutral. Possible to be uncertain --> "mixed feelings"
Describe the dual nature of light
light is both a particle and a wave (supported by the photoelectric effect)
What is plane-polarized light
light that exists in only a single plane
Characteristics of T-cells (Helper vs suppressor vs Killer)
lymphocyte mature in the thymus and participate in cell-mediated immunity. Recognize and bind antigens via a "T-cell receptor" (TCR) not found in B-cells Helper: T-cells that help other immune system cells such as B-cells and cytotoxic T-cells to perform their function Suppressor: AKA regulatory T-cells; suppress body's own immune system. Helps prevent severe allergic reactions or autoimmune disease and AIDs in turning off an immune response once an infection has been eliminated Killer: AKA cytotoxic T-cells; target infected and cancerous versions of the body's own cells and destroy them
What are cultural barriers
may occur when a person of one culture interacts with a person of another culture. Beliefs, attitudes, and customs may clash. Example of this would be accommodating religious preferences in the work place
What are semantics?
meaning of language and involve how meaning is changed as a function of relationship among the words that are used
What is entropy, measurement, and value indications
measure of randomness/disorder in a system ∆S; measured in J/K Positive ∆S= increased randomness, more energy available to do work Negative ∆S= decreased randomness, less energy available to do work
What is gauge pressure?
measured with respect to atmospheric pressure
What is absolute temperature
measurement with Kelvin. Absolute 0 (K) is the theoretical limit where all molecular motion ceases
What is the function of the digestive system
mechanical and chemical digestion of food into monomers and simple components for absorption and later use as source energy, carbon chains, and amino acids
What is the acromsome
membrane-bound structure on top of head of each sperm contains hydrolytic enzyme to break down impenetrable coating around ovum
Heightened emotional state on memory
memories encoded during heightened emotional states are usually remembered easier
Acetyl
methyl attached to a carbonyl
What is threshold (psych) Two different types
minimum magnitude of a stimulus, or difference in magnitude of two stimuli, that can be perceived by the CNS Absolute threshold- the lowest level of stimulus that na organism can detect Difference threshold- the smallest amount by which two sensory stimuli can differ in order for an individual to perceive them as different (The threshold of conscious perception is the lowest limit of sensibility)
Describe column chromatography
mixture separated passes through a column packed with charged glass beads, or some other polar matrix Solution is collected in fractions at the bottom of the column The most non-polar substances will elute first, and most polar will elute last
Molarity
mol/L
Describe how mass spectrometry works What is the parent/base peak?
molecules are bombarded with electrons causing them to break apart into smaller pieces. The fragments are then accelerated through flight tube. Graph will show the height of each peak (MW) relative to the abundance of that fragment. Parent peak=original molecule minus one electron. Is the furthest right on the spec. Labeled with M+ Base peak= most common fragment, usually most stable fragment. Exists as 100% relative abundance, with all other peaks compared.
What is a meso compound
molecules with 2 or more chiral centers that contain a plane of symmetry Symmetry will cancel out their optical activity A single molecule
Characteristics of monocytes/macrophages
monocytes mature into macrophages Macrophages phagocytize pathogens and cellular debris. Phagocytosis by macrophages is non-specific and a type of innate immunity but macrophages also present antigens from pathogens they consume for recognition by B and T cells --> An aspect of acquired immunity
What do monozygotic vs dizygotic twin studies examine
monozygotic twins= genetic influence is controlled; studies examine twins raised in different homes so that environmental influence is variable dizygotic twins=genetic influence is variable; studies examine twins in the same home, so that environmental influence is controlled
Describe the characteristics of the diaphragm
moves down when flexed and moves up when relaxed. When relaxed it has an upward-oriented convex shape. When flexed it is flat Moves down during inhalation, moves up during exhalation
What is myoglobin
muscles own oxygen storage molecule Is one subunit of hemoglobin, capable of holding one O2 molecule
Characteristics of arteries Characteristics of veins
muscular, thick-walled vessels that push blood through via rhythmic contraction thin-walled vessels with little to no musculature that rely on a valve system to move blood back toward the heart
What are fungi? Describe
mushrooms, yeasts, molds All are heterotrophs; most are saprophytic (live off dead, decaying matter), but a few are parasitic (live off host, killing it), or mutualistic Have walls made of chitin, spend most of life as haploid, grow via long intertwining branches called hyphae, and yeasts reproduce almost exclusively from budding
What is the 4th quantum number
m∨s: magnetic spin either +1/2 or -1/2; positive spin is half arrow up, negative is half arrow down
What are the 4 quantum numbers
n: principle quantum number, describes the shell and approximate energy l: azimuthal quantum number, describes the subshell/orbital (s,p,d,f) ml: magnetic quantum number, gives orbital orientation of -l to +l ms: magnetic spin, either +1/2 or -1/2
What is Secondary Active Transport
no direct coupling of ATP required, is instead carrier mediated Antiport or symport
What is genetic imprinting?
one specific gene is expressed differently depending on which parent it originated from
What is a non-zero sum game?
one's gain is not balanced by losses of others
Describe the role of group memberships
one's identity is tightly associated with the groups to which one belongs. Religion, nationalism, ethnicity
What is locus of control? Internal vs External
one's personal belief regarding the degree to which one can or cannot control life events or outcomes Internal= i believe i primarily control and determine outcomes External= i believe external events or influences beyond my control determine outcomes
What is depolarization
opening of voltage-gated sodium channels causes a sudden spike in membrane potential from -70mV to +40mV
Describe friction (Kinetic vs Static) and equation
opposition of sliding, NOT motion Kinetic= if object is sliding Static=if object is not sliding F(f)=µF(N) or F(f)=µmgcosθ
What is hydroxyapatite?
organic compound of calcium, phosphate, and hydroxide this is the mineral matrix responsible for a bone's strength and is form in which most all of body's calcium is stored
What would reliance on central traits be
our perception of others is affected by focusing on characteristics that are of particular interest to us
Probability assumption and how to find probabilities
outcomes are independent and are mutually exclusive if the probabilities say "and"-multiply the probabilities of individual events to get overall probability if the probabilities say "or"-add probabilities of individual events to get probability of ANY of the events
What is human subject research and what are the kinds?
outside the lab Drug trials Less control than basic science research Experimental-specific intervention controlled by investigator Observational-investigator observes data without direct control over variable
What is a schema
pattern of thought we use to create categories of information or behavior and to understand the relationship that exists among these categories. Help process tremendous amount of information we receive daily, but also bias the ways that we deal with new information We will assimilate things to fit the schema, but we can also amend our schemas
What is antisocial personality disorder? What cluster is it a part of?
persistent pattern of disregard for and violation of the rights of others. May be accompanied by cruelty to animals, lack of concern for others, difficulty feeling empathy for others, impulsivity, aggressiveness or irritability, failure to conform to social norms, etc. Symptoms usually begin in childhood and include such things as setting fires, legal trouble, and difficulty with authority. -Is never diagnosed before the age of 18 -Must include some symptoms before the age of 15 -Severe cases are further classified as a sociopath or a psychopath Cluster B
Describe trait personality theories
personality is the sum of broad, relatively stable characteristics or dispositions, called traits. More focused on unique differences between individuals, whereas psychoanalytical or humanistic focuses more on commonalities among all people
What is the elaboration likelihood model?
persuading someone to change their attitudes about a situation Central route: thoughtful consideration of information that is being presented. More likely to have a lasting change, but person being persuaded must have an open mind Peripheral route: when person being persuaded has very little interest in subject. Persuaded by the impressions of person trying to persuade. Can cause attitude change, but shorter-lived than central
What is a supercritical fluid
phase once the critical point on a phase diagram is hit. At this point, the liquid and gas phases are indistinguishable and are now known as a supercritical fluid Cannot go back from this phase
What is incomplete dominance?
phenotypes of the dominant and recessive alleles appear to be mixed or blended in the phenotype of a heterozygote (Red and white give pink flower)
Describe what vacuum filtration is
physical separation of a solid from a liquid by performance of a Hirsch or Buchner funnel Same process as used in gravity filtration, except it is faster
Sensory Adaptation
physiological phenomena that occurs when sensory receptors automatically become less sensitive to a repetitive stimulus over time First walk into a candle store and the smell overwhelms you, but you eventually adapt
Maslow's Hierarchy of Needs
physiological, safety, love/belonging, esteem, self-actualization
Describe the nucleophilicity of alkenes
pi electron in double bond will attack electrophiles forming a new bond with one of the carbons and leaving the other as a carbocation, which is then quenched by a nucleophile
What is polygyny vs polyandry?
polygyny= marriage between one man and 2 (+) women polyandry=marriage between one woman and 2(+) men. This is very rare Polygamy is more normal in lower income countries, whereas monogamy is the norm of the majority of countries today
What is absolute refractory period
portion of time during which an action potential cannot be initiated regardless of strength of stimulus Occurs during progression of previous action potential
ADH: location, class function
posterior pituitary peptide/water-soluble causes the collecting duct of the kidney to become highly permeable to water, concentrating the urine
Oxytocin: location, class, function
posterior pituitary peptide/water-soluble stimulates contractions during childbirth and milk secretion during nursing
What is mental set and how can it effect problem solving
predetermined mental framework for approaching a problem. Has the tendency to rely on approaches and solutions that have worked in the past Can lead to rigid thinking and lack of cognitive flexibility
Electronegativity in nucleophilicity and electrophilicity
predict nuc/elec based on partial positive/negative charges (nucleophile=partial or full negative; Electrophile=partial or full positive)
Definition of valence shell electron pair repulsion theory
predicts which shape molecules will take due to repulsion of lone pairs of electrons
What is the difference between prejudice and discrimination
prejudice is an attitude; whereas discrimination is an actual behavior
What is exocytosis
process by which a vesicle on the inside of the plasma membrane fuses with the plasma membrane, dumping it's contents into the extracellular matrix
What is ketogenesis
process by which ketone bodies are produced through the breakdown of fatty acids. Occurs during periods of starvation when blood glucose drops and there's no further source of carbohydrate
What is role exit
process by which people disengage from important social roles
What is modeling in learning
process of learning a behavior by watching others and mimicking their behavior only ONE way we can learn through observation observing can also result in us not modeling (brother touches hot stove so you dont)
What is solvation
process wherein solvent molecules surround a dissolved ion or other particles, creating a shell
Characteristics of integral proteins
proteins that have 1(+) moieties embedded within the bilayer (plasma membrane)
3rd Law of Thermodynamics
pure crystalline substances at absolute zero have an entropy of zero
Standard Deviation of mean (SEM)
quantification of how precisely the mean represents true mean of population SEM decreases as sample size increases
Describe characteristics of Hemoglobin
quaternary protein made of 4 protein chains; 2 alpha and 2 beta. Each has an Fe-containing "heme" group at its center so it can hold 4 O2 total.
What is racial formation
racial categories are not permanent or easily defined, but are constructed by various forces in history and society. Racial identities can be created, strengthened, and destroyed, and are always fluid
pH scale (describe and equations)
ranks solutions based on their influence to the equilibrium for ionization of water pH=-log[H⁺] pOH=-log[OH⁻] pH+pOH=14
Spontaneous recovery in classical conditioning
re-emergence of a previously extinguished conditioned response after a delay
Describe transesterification
reaction of an ester with an alcohol, to create a different ester
What is the area under the peak of an H-NMR graph show
relative representation of the number of hydrogen atoms account for by that peak. A higher peak signifies more chemically equivalent hydrogens in that area
What does volatile mean?
relative tendency of a substance to form a vapor. If "Substance A is more volatile than B", then A has a higher vapor pressure
Reliability vs validity
reliability= results are consistent and repeatable validity= test or experiment measures what it purports to measure and uses methods that meet scientific standards
What is the Thematic Apperception Test?
respondents are provided with a series of ambiguous pictures and are asked to come up with a dramatic story about the picture
What does the visual cortex do and where is it located
responsible for processing visual stimuli part of the occipital lobe
What is the isoelectric point (describe and how to find the values)
same as the equivalence point in acid base titration pH at which a molecule carries no net charge (zwitterion) pI=pKa1 + pKa2 / 2
Describe electric potential energy
same(ish) as gravitational PE How much energy that particle has when it is close to the charge source. Closer to the source of charge, the smaller the energy
Anterior pituitary function Derived from where?
secretes FSH, LH, ACTH, TSH, Prolactin, and GH (Mnemonic: FLAT PiG) Pituitary gland is derived from the ectodermal layer, the anterior pituitary is derived from the oral ectoderm region
Role of prostate gland
secretes a white milky fluid that is slightly acidic and contains proteases Plays protective role: sperm have longer survival rates and better protection of genetic material in presence of prostate secretions compared to without
Describe electric dipoles
separation of positive and negative charges of equal magnitude. When a dipole is exposed to an electric field it tends to align itself with field Dipole not aligned with electric field has potential energy because alignment with the field is a lower energy state than alignment against the field
Describe intracrine signaling
signal molecules (usually steroids) bind to receptors inside the same cell that produced them without ever being secreted out of the cell
Describe autocrine signaling
signal molecules secreted by a cell bind to receptors on the same cell
Describe paracrine signaling
signal molecules secreted by one cell bind to receptor on other cells in local area example would be neurotransmitter acting in synaptic gap
What are vitamins? Which are fat-soluble/water? Easier to OD on which?
small organic molecules that are essential nutrients required for proper metabolism Fat soluble= A,D,E,K Water soluble= B and C Easier to OD on fat soluble because they are stored in fat tissue, whereas water are excreted through urine quicker
What are morphemes? Morphology?
smallest unit of language that carries meaning. Can be used by combining one or more phonemes together Morphology involves focusing on how words are formed from combinations of morphemes
What is exchange mobility
social classes maintain a relatively static number of people Should a set number of people move up from middle class, an equal number of people is expected to move down from upper class
What is class consciousness (social class)
social condition in which members of a social class are aware of themselves as a class
What is conflict theory?
social life is characterized by inequality where groups and individuals compete for scarce resources. This results in various levels of wealth, power, and prestige across society. Effects everyday social interactions at the micro level and more macro phenomena. This theory is interested in how inequality is reproduced
What is social control
societal or political mechanisms used to regulate behavior of individuals to ensure conformity and compliance to established rules of that group
What is modernization?
societal transformation away from a traditional, rural, agrarian society, and toward a secular, urban, industrial society.
What is strain theory of deviance
society promotes deviant behavior. Puts pressure on individuals to achieve goals that may not be attainable, so they deviate
What is a precipitate
solid formed inside a solution as a result of chemical reaction. This is only formed when ion product exceeds solubility product constant
Describe phases in chemistry
solid, liquid, and gas forms Things are in the same phase if they are in the same state, have the same chemical composition, and are structurally homogenous
What is a supersaturated solution
solution contains more dissolved solute than predicted by solubility product constant without having precipitate formed. This usually only happens at high temperatures
Describe colloids
solvents containing undissolved solute particles that are too small to be separated by filtration, but larger than solute particles. Scatter light Are NOT solutions
What are feature detectors in vision
some cells in the visual system that are so sensitive to, and have the ability to discriminate very complex stimuli with only minute differences
What is culture lag
some cultural elements change more quickly than others, causing conflict with the cultural system. An example of this would be the use of drones, and how the technology outpaced public policy and laws
Aging and memory (describe the relationship)
some degree of mild memory loss is considered normal with aging; but a significant amount of forgetting is likely due to age-related physiological changes or disease Sharpest, most noticeable decline is in episodic and source memory There is little to no decline in semantic memory
Cohort study
some people are exposed to a risk factor, wait for a time period, and see who develops the disease. Draw conclusions about risk factor correlating with disease.
Define temperament
somewhat ambiguous term describing one's general emotional disposition has been shown to be established at birth and relatively persistent across the life span
Role of spleen in immune system
somewhat analogous to a lymph node that filters blood instead of lymph; High concentration of leukocytes and platelets Storage of a considerable amount of blood that can help combat hemorrhagic shock; breaks down and recycles parts of old erythrocytes
Describe how sound waves are produced
sound is always created by a vibrating medium. Vibrations propagate through liquids or solids and generate pressure waves that propagate through gases such as air. They are mechanical waves, so they cannot propagate through a vacuum
Hybridization shapes and bond angles (5)
sp= linear and 180 sp2=trigonal planar or bent; 120 sp3= tetrahedral, trigonal pyramidal, or bent; 109.5 sp3d=trigonal bipyramidal, seesaw, T-shaped, or linear; 90/120 or 180 sp3d2=octahedral, square pyramidal, or square planar; 90
What is a kinetochore
specialized group of proteins to which spindle fibers attach during mitosis
What are pheromones
specialized odors released by one individual that elicit behavior in another individual. These are more common in animals than in humans
What is standard state (with respect to enthalpy)
specific conditions chosen as the reference point =∆H° Given as a table value Elements in their standard state have a ∆H°(formation)=0 because there is no energy to create no ∆H° for graphite, but there is for diamonds
What is acquired immunity? What are the 2 types
specific response to one particular virus, bacteria, or other pathogen based upon prior exposure. Humoral immunity: AKA B-cell immunity or antibody mediated immunity. (When you see B-cell immunity think humoral). Antibodies and primary/secondary response Cell-mediated: AKA T-cell immunity; self attack of diseased cells
Spermatozoa characteristics
sperm produced in seminiferous tubules of testicles, stored and nurtured in epididymis Head is cell body, tail is flagellum; contains lots of mitochondria
Describe the ejaculation pathway
sperm leaves epididymis via vas deferens. Vas deferens arch back up into pelvis and then back down toward penis. Along the way, seminal vesicles, prostate gland, and bulbourethral gland (Cowpers) all secrete various lubricants and nutrients into the ejaculate. Vas deferens empty into the urethra at base of urinary bladder
Describe spin-spin splitting in H-NMR
spin-spin splitting is the result of the presence of neighboring hydrogen atoms. n+1 sub-peaks= the number of non-equivalent hydrogen neighbors
What is divided attention
splitting attention among multiple tasks would do this while driving and car and engaged in a conversation
Define metastasis
spreading of cancer from one tissue or organ to another
Define alertness
state of consciousness in which a person is awake, responsive, and capable of processing information
What is status? Achieved vs ascribed?
status=one's hierarchal position in society, inherently suggests inequality Achieved status=a status that is earned through personal effort and achievement Ascribed status=status assigned at birth or assumed involuntary based on race, ethnicity, lineage, etc
What is the function of the gall bladder? What is bile emulsification?
stores and concentrates bile, but does not produce bile (liver). Bile emulsifies fats (separates fats from each other, which increases surface area for enzymatic digestion) Bile emulsification is physical digestion because emulsifies them, and doesn't actually break bonds
Describe what a capacitor does
stores energy and charge by holding electrons on plates separated by a very small distance Capacitance will stay the same until fully charged to the amount of voltage C=Q/V (Capacitance is in Farads: C/V)
What is self-efficacy
strength of a person's belief in their own abilities Self-evaluation of one's ability; my ability
Characteristics of adherens junctions (ex of where found)
strong mechanical attachments Found in epithelial and cardiac muscle
Characteristics of desmosomes (ex of where found)
strongest of the cellular junctions weld cells together and protect against stress, but are NOT watertight Found in the epidermis
What is a dielectric
substance between two capacitor plates. Can be air, gels, composites, whatever. Increase the dielectric, increase the capacitance
What does optically inactive mean
substance that does NOT rotate plane-polarized light
Amphoteric species
substances that can be an acid or a base
Substrate level phosphorylation vs oxidative phosphorylation
substrate level= phosphate is transferred to ADP or GDP. This process is used by citric acid cycle step 5) Oxidative phosphorylation= in ATP synthase and ETC; combine ADP to Pi to generate ATP through proton gradient. Oxidizes NADH and FADH2 from Krebs for the protons
What is cataplexy?
sudden transient periods of muscle weakness or paralysis during which the patient remains fully conscious and aware
What is glycogenesis? Where?
synthesis of glycogen for storage in the liver This is stimulated by insulin
What does the parietal lobe control
tactile sensation, spatial reasoning, and some language (secondary to frontal)
What is groupthink
tendency of groups to make decisions that are incorrect or illogical based on desire to maximize group consensus and minimize group conflict Often results in the group ignoring conflicting information or evidence, or dismissing something without consideration
What is group polarization
tendency of groups to make decisions that are more extreme than the individual members would acting alone
What is chemical digestion
the breakdown of food that involves breaking of bonds with digestive enzymes
Describe Recrystallization process
the desired product (which contains impurities) is dissolved in minimum amount of hot solvent necessary to create a saturated solution. The solution is then cooled as slowly as possible. Pure substances usually crystallize at high temperatures than impure. So if temp is dropped just below melting point of product, crystals formed will be product and impurities will remain in solution A higher and sharper MP indicates better purity. Impurities lower and broaden the MP
What is relative deprivation
the experience of being deprived of something to which one believes to be entitled; it is said to be relative because it usually arises from comparing one's situations to that of others and feeling that one has less than what one deserves Considered a potential cause of social movements and deviance
What is the origin of replication? Bidirectional?
the location on the chromosome where replication begins. There are multiple in humans replication proceeds in both directions simultaneously from the origin of replication
What is carrying capacity?
the maximum number of organisms and environment or ecosystem can sustain.
What is osmotic pressure
the measure of tendency of water to move from one solution to another across semi-permeable membrane The side that receives the water via osmosis has the higher osmotic pressure Represented by π π=iMRT: i=# of ions formed in solution; M= solute molarity; R= gas constant; T=absolute temp
What is terminal velocity? Equation?
the object has stopped accelerating and the force of gravity and air resistance are now balanced mg=F(air)
Enzymes in saliva
the only enzyme is alpha amylase. This is the first enzyme to which food is exposed in digestive tract
What is gender segregation
the physical, legal, or social segregation of individuals according to sex. (separate gym classes for girls and boys, different legal treatments for men and women, encouraging young women to pursue traditional female careers such as teaching or nursing)
What is multiculturalism?
the presence of, or support for the presence of, several distinct cultural or ethnic groups within a society. This is in opposition to melting pot, in which everyone becomes like one another
Describe the resonance of the peptide bond and it's functionality
the resonance allows for a rigid peptide bond with limited rotation
What determines the shape possibilities and the exact shape of molecules
the shape possibilities is determined by hybridization. The exact shape is determined by the presence or absence of unpaired electrons
Describe the dominant hemisphere of brain
the side of the brain that is used in controlling the preferred arm or leg. Most individuals are right handed, and therefore are their dominant hemisphere is usually the left
What is social exclusion
the systematic blocking of a segment of society from the rights and opportunities available to others
What is the sick role? What would rights of a sick person be? Obligations?
theory that explains a sick person having a unique role in society that includes both rights and obligations. Being sick is seen as a temporary form of deviance that prevents a person from being a productive member of society during their illness. Rights of a sick person= exempt from normal social roles and expectations; not responsible or to be blamed for their condition Obligations of a sick person= attempt to get well as soon as possible; seek help and cooperate with medical professionals
T3 and T4: location, class, function
thyroid tyrosine derivative/lipid-soluble increases basal metabolic rate, effecting metabolism
Period of a wave
time for one full wavelength to pass a fixed point (in seconds)
Characteristics of platelets
tiny membrane bound drops of cytoplasm Are sticky when exposed to injured epithelium. If they encounter injured epithelium, they release chemicals that activate other platelets and clotting factors Are derived from megakaryocytes (in bone marrow). Mature megakaryocytes produce small fragments which they release into circulating blood which become platelets
Function of chromosomes
to efficiently package very long DNA so they can be easily stored and moved during division
Describe the formation of mesylates and tosylates
tosyl/mesylates make very good leaving groups that will react readily with most nucleophiles 1. alcohol will attack tosyl/mesyl halide via SN2 reaction, kicking off halide ion 2. Hydrogen is abstracted by halide, quenching the charge on oxygen
What is vital capacity
total volume of air the lungs can hold at maximal inhalation minus the residual volume
Describe auditory processing and the pathway
transmission pathway of auditory impulse hair cells of inner ear-->vestibulocochlear nerve --> brain stem --> medial geniculate nerve (MGN); part of the thalamus --> Auditory cortex (temporal lobe)
Characteristics of gap junctions (ex of where found)
tunnels between adjacent cells allowing exchange Found between cardiac muscle cells
What is phagocytosis
type of endocytosis specifically referring to engulfing large particles, bacteria, etc.
How are lipids metabolized
via β-oxidation of fatty acids occurs in the mitochondrial matrix; extra long chain fatty acids first enter a peroxisome and are catabolized into smaller pieces. These pieces are then oxidized in mitochondria Utilize carnitine shuttle because fatty acids can't cross inner mitochondrial membrane Carbons will be removed 2 at a time to form Acetyl-CoA NET RESULT= 1FADH2, 1 NADH, and 1 acetyl-coa
What is game theory
views social or group behaviors as a game with players, winners, losers, prizes, and other outcomes. Assumed that individuals or groups make decisions on outcomes, based on ultimate goal of winning
What is deviance
violation of cultural norms
What is a disease that inhibits the function of the large intestine likely going to be caused by
vitamin deficiency, diarrhea, or constipation
What is tidal volume
volume of air that enters and exits the lungs during an average, unforced respiration
Describe skeletal muscle
voluntary, striated, multinucleated attaches at tendons (muscle to bone) and ligaments (bone to bone) Joints formed by most muscles and bones in human body are hinges with poor lever systems that works at a mechanical disadvantage store large amounts of glycogen are suspended in G0 and don't divide
What are second-messenger systems?
water-soluble hormones bind to membrane receptors on external surface of plasma membrane. This will then most often initiate a cascade-event that magnifies the signal (G-proteins are a common second messenger system)
What is interpersonal attraction
we "like" other people because of similarities, complementary differences, etc
What is overconfidence bias
we're very unlikely to question the wisdom of our decisions
What is apparent weight
weight of submerged object is the actual weight minus buoyant force AW=aW(actual weight)-F(buoyant)
Describe heat of combustion
when molecules are combusted, all of the bonds are broken and reformed via a radical reaction The less stable a bond, the greater the heat of combustion The more stable the bond, the lesser the heat of combustion
How many radians in a circle?
~6 radians/circle
Difference between ∆G, ∆G°, and ∆G°'
∆G=Free energy change at some present, non-standard set of conditions ∆G°= Free energy change at standard conditions; 25°C, 1 atm, [1M] ∆G°'=Free energy change at standard physiological conditions; pH=7 Think of ∆G° and ∆G°' as same, but with pH specified
Equation to find ∆G°'
∆G=∆G°'+RTlnQ Think of ∆G°' as the a constant, given that it will not change. R=universal gas constant Q=reaction quotient OR ∆G°'=-RTlnKeq (∆G=0; Keq=Q)
What is the fundamental thermodynamic relationship? (Equation) What do each negative and positive values indicate for each?
∆G=∆H-T∆S G=Gibbs Free Energy H=Enthalpy S=Entropy T=Kelvin A negative G means the reaction is spontaneous. Positive G means the reaction is non-spontaneous. If G=0, then the reaction is at equilibrium A reaction is favorable if H is negative and/or S is positive
What is the relationship between free energy and chemical energy?
∆G°=-nFE° n= # of moles of electrons transferred F=Faraday's constant Therefore a +E°=-∆G°=spontaneous A positive Electrical potential means a negative change in free energy; indicating the process is spontaneous
Describe when ∆Hsolution values would be positive or negative
∆Hsolution >0 if new intermolecular forces are less than the sum of intermolecular forces broken. This is endothermic and heat must be added to make the solute dissolve ∆Hsolution < 0 if new intermolecular forces formed are greater than the sum of intermolecular forces broken. This is exothermic and heat is evolved
Tell the story of DNA replication
*Helicase* unzips double helix at the beginning. *Single-strand binding protein* coat individual strands to prevent re-annealing. They are then fed through replication complex that contains all necessary proteins for replication. *Primase* (RNA polymerase) then constructs short primers on both strands of DNA. Two DNA polymerase molecules then begin building new complementary DNA strands. They are read in the 3' to 5' direction, and build the new strands in 5' to 3' direction. *Sliding Clamp* is a protein that helps keep DNA polymerase tightly associated with the strand. Both enzymes move in opposite direction in the 3' to 5' direction. The enzyme working on the *Lagging Strand* must copy short segments downstream, release from strand, move upstream, and copy another short segment. *Leading Strand* requires only a single primer, while the lagging strand requires multiple primers, one for each of the *Okazaki Fragments*. *RNase H* removes all RNA primers after replication. DNA polymerase then fills in the gaps. *DNA Ligase* creates the last necessary phosphodiester bond.
Describe what NMR is and how it works
*must have an odd atomic number or odd atomic mass nuclei with odd atomic number/mass have nuclear spin. External magnetic field is applied to group of nuclei and they align their magnetic fields with the direction of external field. --> Then exposed to photons, and some of nuclei absorb and flip their orientation so they are aligned against external field. The absorbance is of this energy is observed by NMR Different nuclei will require different frequencies of photons to cause flip in orientation. The different results are caused by shielding.
What things create a magnetic field (4)
-nuclei with an odd atomic or mass number (nuclear spin) -Electrons (because they orbit and spin) -Current (because it is moving electrons) -Bar magnets (usually made of nickel, iron, or associated alloy
What are the steps of the citric acid cycle
1. Acetyl-CoA (2C) joins with oxaloacetate (4C) and forms citrate (6C) via citrate synthase; CoA is released 2. Aconitase converts citrate to isocitrate 3. Isocitrate is converted to α-ketoglutarate dehydrogenase by isocitrate dehydrogenase; NAD⁺ is reduced to NADH + H⁺ and CO₂ si released 4. α-ketoglutarate is converted to succinyl CoA by α-ketoglutarate dehydrogenase complex; NAD⁺ and CoA enter and NADH and H⁺ and CO₂ released 5. Succinyl CoA is converted to succinate by succinyl CoA synthetase; GDP and Pi converted to GTP and CoA released 6. Succinate converted to fumarate by succinate dehydrogenase; FAD to FADH₂ release 7. Fumarate and H₂O converted to malate by fumarase 8. Malate to oxaloacetate by malate dehydrogenase; NAD⁺ to NADH + H⁺ **DON'T worry about memorizing enzymes
What are the 3 primary components of attitude
1. Cognitive: how you think about something/somebody 2. Affective (emotional): how you feel about something/somebody 3. Behavioral: how you behave toward or with respect to something/somebody
What are the 4 stages of sleep, describe the EEG during each
1. Falling asleep, EEG is a mix of alpha and theta waves 2. Deeper sleep, EEG is theta waves mixed with sleep spindles and K complexes 3. Transitional, EEG is mostly theta waves, but delta waves begin to appear 4. Deep sleep, often called delta sleep because EEG contains slow low frequency delta waves
What are the 6 interactions between amino acids (briefly describe them)
1. H-bonding: non-covalent between amide and carboxyl or between R groups 2. Disulfide bonds: covalent bonds between sulfurs of 2 Cysteines 3. Hydrophobic/philic: in soluble proteins, hydrophobic AA collapse inward to protein core. In membrane proteins hydrophilic members are toward the outside 4. Ionic interactions: Salt bridges; formed by charged interactions between positively and negatively charged AA 5. Van der Walls Force: intermolecular force that repels aways from each other (steric hindrance) 6. Proline turns: first in alpha, and at turns in beta
What are the 3 functions that the functional attitude theory asserts?
1. Knowledge: attitudes give us valuable information about other people, events, and likelihood of outcomes 2. Ego-expression: attitudes are one route through which we express ourselves 3. Adaptive: socially acceptable attitudes provide an adaptive advantage in society much like certain random mutations provide an evolutionary advantage
What are the 4 types of stomach lining cell types and what do they do
1. Mucous neck cells: make and secrete mucus into gastric pits, which leads to the stomach. Mucus is alkaline, providing protection from acidic stomach 2. Chief Cells: make and secrete pepsinogen into gastric pits/stomach 3. Parietal Cells: secrete HCl into gastric pits. Keeps stomach pH ~2. Also converts pepsinogen to pepsin 4. G-Cells: Make and secrete gastrin, which enhances digestion.
Describe the role of the Pentose Phosphate pathway, and what they do
1. NADPH synthesis: important reducing agent in reductive biosynthesis (synthesize fatty acids and sterols) 2. Ribose-5-Phosphate (R5-P): synthesize nucleotides. It is the oxygen bearing ring of all nucleotides
Freud's stages of psychosexual development
1. Oral: mouth of an infant is primary erogenous zone 2. Anal: 18mo-3years; Anus is primary erogenous zone; pleasure derived from controlling bowel/bladder movements 3. Phallic: 3-6years; Genitalia is erogenous zone 4. Latency: Relative calm between phallic and genital stage 5. Genital: Strong sexual interest in people outside family
What are the 3 destinations of pyruvate
1. PDH complex: where they're converted to Acetyl-Coa for Krebs 2. Lactate dehydrogenase: gives rise to lactate 3. Pyruvate decarboxylase: gives rise to oxaloacetate
What are 4 mechanisms of DNA repair and describe them
1. Proofreading: DNA polymerase proofreads, catches, and repairs most mismatched pairs on the spot 2. Mismatched repair system: enzymes that scan newly copied DNA and locate, excise and replace mismatched pairs missed by DNA polymerase 3. Base excision: the base portion is only excised via DNA glycosylase; other enzymes will then remove sugar-phosphate backbone; the DNA polymerase and ligase replace the nucleotide 4. Nucleotide excision: excision of oligonucleotide that includes several bases, on either side of error. DNA polymerase and ligase replace
Describe the oxidation of a primary alcohol
1. R-CH2-OH oxidized to aldehyde (R-COH) 2. Then further oxidized to become carboxylic acid (R-COOH)
What are the 3 mechanisms of gene regulation?
1. Rate of transcription: RNA has short half-life, so gene products will only continue to be expressed if DNA is continually transcribed. 2. Activators and Repressors: Regulatory molecules may upregulate transcription (lactose in lac operon) or downregulate (glucose in lac operon). Often hormones, products of rxn cascade, byproducts that buildup, etc. 3. Permanent or semi-permanent suppression: methylation or other covalent modifications that prevents or dramatically decreases transcription
What are Piaget's stages of cognitive development (briefly describe them)
1. Sensorimotor: 0-2 years. Coordinate senses with motor responses, sensory curiosity about the world. Language is used for demands and cataloging. Object Permanence developed 2. Preoperational: 2-7. Symbolic thinking, use of proper syntax and grammar to express full concepts. Imagination and intuition are strong, but abstract thought is still difficult. Conservation is developed. 3. Concrete operational: 7-11. Concepts attached to concrete situations. Time, space, and quantity are understood and can be applied, but not as independent concepts 4. Formal operation: 11+. Theoretical. hypothetical, and counterfactual thinking. Abstract logic and reasoning. Strategy and planning become possible. Concepts learned in one context can be applied to another
What are the two main ways that ATP is formed and describe them
1. Substrate level phosphorylation: The formation of ATP from ADP. This usually occurs in the cytosol as a part of glycolysis, but sometimes can occur in the mitochondrial matrix. MUST BE COUPLED TO AN EXERGONIC REACTION TO PROCEED. 2. Oxidative Phosphorylation: Forms ATP out of ADP and Pi from the energy of the proton gradient across the inner mitochondrial membrane. (Protons from oxidation of NADH and FADH2)
How we think (information processing model 4 parts and describe them)
1. Thinking: perception of stimuli, encoding, and storage for later 2. Analysis of stimuli: stimuli is altered and analyzed by the brain, not just responded to automatically 3. Situational modification: stored decision-making and problem-solving experiences from past can be extrapolated to solve new problems 4. Obstacle Evaluation: Skill level in problem solving doesn't depend solely on cognitive development level, but largely on nature and context of problem/obstacle
What are the 3 types of encoding and describe them
1. Visual-encoding of an image or visualization 2. Acoustic- encoding of sound 3. Semantic- encoding of meaning, understanding, or interrelation with other previously stored information
Describe the SN1 reaction of forming an alkyl halide from an alcohol
1. alcohol acts as nucleophile, attacking electrophilic halide hydrogen, forms good leaving group water and halide ion 2. Good leaving group, water, spontaneously dissociates (rate-limiting) leaving a carbocation 3. Halide attacks carbocation, forming product
Describe the SN2 reaction of forming an alkyl halide from an alcohol
1. alcohol acts as nucleophile, attacking the electrophilic halide hydrogen and forming good leaving group water plus the halide 2. halide attacks the central carbon, kicking off water
Order of deprotonation in an amino acid
1. α-COOH (pKa ~ 2) 2. Acidic R group (pKa ~4): Asp=3.7; Glu=4.5 3. His R Group (pKa ~6) 4. α-NH₃⁺ (pKa ~9) 5. Basic R group (pka ~11-12): Lys=10.7; Arg=12
Erickson: Autonomy vs. Shame and Doubt
1.5 to 3 years Favorable: sense of self-efficacy Negative: self doubt
left ventricle
10
renal vein
10
Describe Freud's Id
100% unconscious Responsible for all instinctive and primitive behaviors the only one of the three components (Id, ego, and superego) that is present from birth Primary or most important component of personality, the "source of all psychic energy" Primary process and Wish Fulfillment
pico- femto- hecto- mega- giga- tera-
10^-12 10^-15 10^2 10^6 10^9 10^12
left pulmonary artery
14
right ventricle
14
left pulmonary veins
15
papillary muscle
15
coronary sinus
16
left ventricle
16
superior vena cava
17
pulmonary valve
2
renal cortex
2
What is the product of one single turn of the citric acid cycle
2 CO₂, 3 NADH, 1 FADH₂, and 1 ATP There are 2 CoA produced by each glycolysis cycle though; so each glycolysis gives 4, 6, 2, 2
Describe the anatomy of long bones
2 epiphyses cushioned by cartilage Ends are filled with spongy bone and shaft in between is made of compact bone Center is hollow cavity filled with yellow bone marrow
What is an isomer
2 molecules that have the same molecular formula but are actually different compounds Maximum number of isomers= 2^n (n=# of chiral centers)
What is the net result of glycolysis? What step does each come from?
2 pyruvates (after step 10 happens twice) 2 NADH (from step 5 happening twice) 2 ATP (NET; 2 lost in steps 1 and 3; 4 gained in steps 7 and 10) 2 H₂O (step 9 happens twice) 2H⁺ (**Step 4 will yield 2 Glyceraldehyde 3-Phosphate so all steps afterwards will yield double)
What are groups
2(+) people interacting and identifying with one another Primary and secondary=large impersonal group of members for a short period of time Family=most influential
Describe visible light (properties and values)
390-700nm ROY G BIV Red has lowest frequency and longest wavelength; Violet has highest frequency and shortest wavelength
Erickson: Generativity vs Stagnation
40 to 65 Favorable: Making contributions to society Negative: Unable to make contributions in meaningful ways
distal convoluted tubule
5
inferior vena cava opening
5
right pulmonary veins
5
Erickson: Industry vs. Inferiority
5 to 12 Favorable: Sense of competence and understanding Negative: Sense of inferiority
collecting duct
6
inferior vena cava
6
juxtaglomerular apparatus Where this distal tubule and afferent arteriole cells meet
6
left ventricle
6
Erickson: Integrity vs. Despair
65+ Favorable: Wisdom and integrity Negative: Dissatisfaction with life's outcomes
right ventricle
7
What is dipole moment? Equation and example of when it would be 0
A dipole moment occurs any time a charge is not evenly distributed through a bond µ=δd; δ=charge, d=distance, µ=dipole moment Molecules with 2(+) dipole moments can still have no net dipole if the geometric orientation cancels out (Carbon tetrachloride)
Characteristics of neutrophils
A granulocyte Phagocytes recruited to areas of inflammation and infection by chemotaxis. They live for only 5 days, but are the most abundant WBC's Pus at a wound is mostly dead neutrophils
What is a nucleotide and what are common nucleotide polymers
A phosphate (or group) bound by a phosphodiester bond to a sugar backbone and a nitrogenous base Common nucleotide polymers would include cAMP, NADH, FADH2, FMN, Coenzyme A, ATP, GTP, UTP, etc.
describe the nativist theory of language development
AKA biological or nature __Psycholinguistic__ Humans are prewired for language at birth and language will naturally emerge as we grow and interact with our environment
Describe the learning theory of language development
AKA environmental, behaviorist, nurture we were born without any knowledge of language and we learn language through classical learning mechanisms and through observational learning
What is fecundity? Total, crude, and age-specific?
AKA fertility rate the average number of children born to each woman in a given population Total fertility rate=the average number of children a woman give's birth to in her lifetime Crude birth rate=the number of live births given in a year for every 1000 people in a population. Crude because the population includes both men and women Age-specific fertility rate= number of births during a specific year or reference period per 1000 women of reproductive age in single or five year groups
Characteristics of lymphatic vessels
AKA lymphangions a lot like veins in that many contain one way valves. Backward flow is restricted when single cells overlap slightly, creating a trap that allows fluid in but not out The entire lymph system eventually drains into two main vessels; right lymphatic duct and thoracic duct--> both merge with large veins in lower portion of neck to dump back into the blood
Norepinephrine (found where, primary regulatory functions, and any correlates to disease or psych disorder)
AKA noradrenaline Found in both the CNS and PNS In CNS, noradrenaline is associated with attention and emotional processing. Anxiety disorders and depression are associated with decreased norepinephrine In PNS, norepinephrine contributes to stress response associated with activity of sympathetic division of the autonomic nervous system
What is social constructionism? What is life-world and how does it tie in
AKA phenomenology or phenomenological sociology This is the study of human experience in everyday life. Interested in how individuals perceive, think, and talk about social life. How individuals assign meaning to perceptions and experiences through interaction Life-world is a consequence, and it is the everyday routines and experiences that are taken for granted
Describe the fasting state
AKA post-absorptive state High glucagon, low insulin levels Higher relative rate of catabolism (vs anabolism) Glycogenolysis= immediate increase Gluconeogenesis=delayed increase (~12 hours)
Describe the well-fed state
AKA postprandial state occurs the first few hours after eating a meal High insulin, low glucagon levels High relative rate of anabolism (vs catabolism); high rate of glycogen and fatty acid synthesis
What is verification (in research methods)?
AKA replication should be able to repeat and verify. If it can't be replicated, then assumed to have some sort of error
What is Social Anxiety Disorder (SAD)
AKA social phobia an overwhelming feeling of anxiety and excessive self-consciousness in everyday social situations. It is characterized by a fear of being judged and feelings of inadequacy, inferiority, embarrassment, humiliation, and depression. May be accompanied by blushing, nausea, excessive sweating, trembling, difficulty speaking, etc
Describe the sodium potassium pump
ATP pump that actively pumps 3 Na+ ions out of the cell and 2 K+ ions into the cell per cycle. Net effect is a more positive charge outside of the cell and a progressively more negative charge inside the cell
Neuromuscular junction (chemical and process)
Acetylcholine (ACh) is the only neurotransmitter at NMJ. When ACh is released from motor neuron at NMJ, an action potential is initiated. Action potential then spreads along muscle cell sarcolemma and down specialized invaginations called T-Tubules (dive deep into muscle) The T-Tubule then interfaces directly with sarcoplasmic reticulum (specialized ER in muscles). Electrochemical impulse then spreads from T-Tubules to SR and the SR releases Ca2+ Ca2+ then initiates muscle contraction After muscle contraction, Ca2+ is actively transported back into the SR
What is the self perception theory
Actions influence attitude because people infer their attitudes by observing their own behavior
Describe the ERG theory of needs
Adaptation and categorization of Maslow's Hierarchs that distills it down to 3 categories: -Existence needs: physiological and safety needs -Relatedness needs: portions of love/belonging and esteem needs -Growth needs: Portions of esteem and self-actualization needs Individual can be motivated by needs from each category simultaneously, whereas Maslow's have to have lower level's satisfied before moving higher
Difference between afferent, efferent, and interneurons
Afferent (Sensory): receive sensory signals from sensory cells Efferent (motor): carry signals to a muscle or gland to respond to stimulus. Interneurons: connect afferent and efferent. Also transfer and process signals. The brain and 90% of all other neurons are interneurons
Where do Pancreatic secretions enter?
All secretions empty into the upper end of the duodenum. Just before emptying into the duodenum the pancreatic duct is joined by the bile duct.
Describe the dehydration of alcohols to form an alkene
An equilibrium reaction. Alkene favors hot, concentrated acid. Alcohol favors cold, dilute acid Major product=most stable, most substituted alkene
Describe barbiturates and benzodiazapenes
Are both depressants (along with alcohol) Agonize GABA neurotransmitter At low doses can result in minor mood changes, and at high doses can result in unconsciousness and death (for alcohol and barbiturates)
What are the basic diagnostic symptoms of bipolar disorder? (DSM)
At least one week of abnormally elevated or irritated mood during which the individual also experiences at least 3 of the following: inflated sense of self, decreased need for sleep, increased talkativeness, racing thoughts, increased distractibility, increased psychomotor activation, excessive involvement in pleasurable, yet risky, activities Change in mood significantly impairs work or family functioning or leads to hospitalization to prevent harm to self or others. Changes are not better explained by the use of some drug or some other medical condition
Automatic vs Controlled Processing
Automatic= no attention or conscious effort required (walking while talking on cell phone) Controlled=Effortful, requires active attention and effort (solving math problem or studying)
Autonomy and Justice in medical ethics
Autonomy- inform pts about and allow them to make decisions Justice-equal treatment of all people
Base dissociation equation
A⁻ + H₂O ⇌ OH⁻ + HA Kb=[OH⁻][HA]/[A-] Ka x Kb= Kw = 10⁻14
Cell Body
B
atrioventricular node
B
Describe boiling point and freezing point with non-volatile additions. Equations for each.
BP is elevated when a non-volatile solute is added (∆T=kbmi) FP is depressed with non-volatile solute is added (∆T=kfmi) kf and kb=constants; m=molality; i=# of ions formed per molecule
Cerebellum is responsible for
Balance and coordination
Tell the story of translation
Begins when small subunit attaches __mRNA__ strand at 5' end. Small subunit will begin scanning mRNA until it reaches start codon, AUG. The first __tRNA__, which will always carry methionine, will have the anticodon 3'UAC5' (complements 5'AUG3'. The process up to this point is considered __initiation__. Complete ribosome then begins moving along mRNA strand from 5' to 3'. There are aminoacyl (A), peptidyl (P), and exit (E) sites on the ribosome. New tRNA molecules carrying associate amino acid enter the A site driven by hydrogen bonding. A peptide bond then forms between the amino acid on the new tRNA and amino acid on the previous tRNA, adjacent to the P site. New tRNA shifts over the P site, and previous tRNA moves to the E site, dissociates from the protein, and exits the ribosome. Another new tRNA enters the A site and the process repeats. This process is called __elongation__. Finally at some point the ribosome will reach a stop codon, stimulating a release factor. This process is called __termination__
Describe the process of the menstrual cycle and the hormones involved
Begins with FSH stimulating the maturation of ovum and follicle in the ovary LH then stimulates cells in ovaries to secrete estrogen which signals the uterine wall to proliferate and prepare for potential pregnancy Just before ovulation, a surge in level of estrogen released causes a subsequent surge in levels of LH (Luteal surge), which signals ovulation and development of corpus luteum Corpus luteum then begins secreting estrogen and high levels of progesterone to signal uterine lining to prepare for implantation If no fertilization occurs, corpus luteum degrades and menstrual lining sloughs off If fertilization does occur, corpus luteum continues to secrete estrogen and progesterone, maintaining pregnancy
How do bacteria reproduce? How do they increase their genetic variability
Binary fission; NO mitosis or meiosis Increase by: 1. Conjugation: one bacteria has an F plasmid (F+); F plasmid is a plasmid containing the gene for a sex pilus. The recipient can be (F-) 2. Transformation: bacteria pick up DNA from the environment 3. Transduction: Viruses accidentally incorporate host genetic material into their nucleic acids
What are the 4 non-enzymatic functions of proteins (examples of them)
Binding: hemoglobin, calmodulin, troponin, tropomyosin, histones, transcription factors, cell adhesion molecules immune system: antigens and antibodies Structural proteins: actin (thin filaments, microfilaments), elastin (connective tissue, extracellular matrix), tubulin (microtubules), and Keratin (hair and nails, intermediate filaments) Motor: Myosin, Kinesins, Dyneins
What is innate immunity
Body's non-specific attack of pathogens. All forms of innate immunity are present at birth, not acquired in any way Immune responses are not specific to one particular virus, bacteria, pathogen, etc Example: skin, stomach acid, enzymes in mucus and saliva, digestive enzymes, blood chemicals, fevers, inflammation, non-specific phagocytosis
What kind of peak is seen at 3300cm-1 on IR?
Broad/Deep= O-H (Separate from C-H) Broad/Shallow= Amine (N-H) Broad/Deep= Amide (N-H connected to carbonyl)
Broca's area and Wernicke's area
Broca's= motor aspects of speech (moving mouth and tongue) Wernicke's= language comprehension Two area's communicate with each other via a bundle of axons called Arcuate Fasciculus. Connection allows integration of language comprehension and speech
Left Bundle Branch
C
Hormones released by the thyroid (characteristics)
Calcitonin Peptide and water-soluble
Describe the role of proline in secondary structure
Causes a kink/turn Usually the first residue at the end of alpha helices, but is rarely found on the inside of the helix Also desirable at the end of beta sheets to make the 180 degree turn to the next row
How is ATP produced by the mitochondria
Cellular respiration starts with glycolysis and results in NADH and FADH2 as the electron carriers. These electrons move down the electron transport chain (series of enzymes on the inner mitochondrial membrane). The H+ ions are then transferred out into the mitochondrial intermembrane space. An increased concentration gradient between the intermembrane space and the matrix forces the electrons through the ATP synthase enzyme channel (into the matrix) The turning of the ATP synthase enzyme results in the phosphorylation of ADP to ATP.
Describe the center of gravity vs the center of buoyancy
Center of gravity=located exactly at the center of mass Center of buoyancy= located at center of mass of fluid displaced, NOT at center of mass of submerged object
Define electron affinity and describe the trend
Change in energy when an electron is added to a neutral atom (How much does an atom want electrons) the numbers become more negative towards the top right (so there is greater electron affinity at top right)
What is Persistent Depressive Disorder (PDD)?
Characterized by Dysthymia, which is depressive symptoms that are not severe enough to qualify as a MDE, but persist most of the time for at least 2 years
What is obsessive-compulsive personality disorder? What cluster is it a part of?
Characterized by a chronic and significant preoccupation with perfection, control and order. May include rigid behaviors, resistance to change, inflexibility, stubbornness, and a sense of helplessness in uncontrollable circumstance Cluster C
What is histrionic personality disorder? What cluster is it a part of?
Characterized by attention-seeking, excessive but shallow emotions, inappropriately seductive behavior or flirtation, and excessive suggestibility. May be accompanied by fleeting moods, opinions, or beliefs. Individuals are often vivacious, dramatic, and have a desire for others to witness their emotional outbursts. Cluster B
What is avoidant personality disorder? What cluster is it a part of?
Characterized by extreme shyness, sensitivity to criticism and rejection, low self-esteem, and avoidance of social situations-including school and work. Individuals may desire closeness with others but have difficulty forming relationships outside of their immediate personality Cluster C
What is borderline personality disorder? What cluster is it a part of?
Characterized by pervasive instability in interpersonal relationships, self-image, and behavior. This instability often disrupts the individuals sense of self-identity and leads to extreme fears of abandonment. May be accompanied by self-destructive behavior, including self-harm or threats of suicide Cluster B
Define chemiosmosis and oxidative phosphorylation
Chemiosmosis: H+ passing though the special channels in ATP synthase and then spinning the axle making ATP from ADP and P+ Oxidative Phosphorylation: ADP being phosphorylated to ATP; happens because of the oxidation of NADH and subsequent enzymes in the ETC.
What is an ambivalent attachment childhood like and what are adults like
Childhood: inconsistent caregiver availability or response to needs. They are upset when caregiver leaves, and are not comforted when they return. May avoid or refuse comfort from parents Adult: reluctant to form relationships, worry partner doesn't reciprocate their love, and are devastated by breakups
What is the difference between a church, sect and a cult?
Church= attempts to appeal to everyone. Has a formalized worship style. Leaders will be educated, trained and ordained. It is long term established and organized. Attracts members that are mainstream Sect= Stands apart from the larger society. It holds rigid religious convictions and does not have a universal appeal. Has a spontaneous and emotionally charged style of worship. Leaders will be charismatic. Is less stable than a church, typically splitting off from other groups. Attracts social outsiders Cult= Also stands apart from larger society. It differs from a sect in that it is outside of society's cultural traditions. Cults can be seen as deviant.
Perchlorate
ClO₄⁻
What are coenzymes What are prosthetic groups
Coenzymes: non-protein species that are NOT permanently attached to the enzyme but are required to function (NAD is common coenzyme) Prosthetic groups: non-protein species that are permanently attached and are required to function
Cohesive vs Adhesive forces
Cohesive=intermolecular forces between the molecules of a liquid, binding the molecules to one another Adhesive=intermolecular forces between the molecule of a liquid and the molecules of a container Adhesive forces are greater than cohesive → seen in the meniscus in water
What is self-concept
Collection of beliefs and self-perceptions about one's own nature, unique abilities and typical behavior Self concept= self-schemas + self-esteem + self-image + self-identity + past self + future self Collective mental picture of self; my total concept of myself Carl Rogers said there are 3 components: self-image, self-esteem, and the ideal self (who i wish i could be)
Conductor vs resistor
Conductor=material that allows flow of electrons through it relatively unimpeded Resistor=material that impedes flow of electrons All conductors resist to some degree, and all resistors conduct to some degree
Cones vs rods
Cones are only in the Fovea. There is a high concentration of cones here and they detect COLOR Rods are found everywhere else in the retina except the fovea. They detect black and white, and are much more sensitive to low light
Describe confrontational tactics vs peaceful tactics in social movements
Confrontational tactics involve obstruction such as sit-ins, human-chain, blocking access, etc. They could also include property damage and violence Peaceful tactics include candlelight vigils, mass demonstrations, cultural politics (AIDs quilt, benefit concerts, etc), or political lobbying
Describe how infrared spectroscopy works
Creates oscillating electric field, which in turn causes dipolar bonds to oscillate at a specific vibrational frequency. Once the dipole bond is in resonance with the infrared radiation frequency, it absorbs some of the energy --> giving us the peaks (transmittance) that we see BONDS WITH NO DIPOLE WILL NOT BE DETECTED BY IR
Describe Snell's law
Describe's the index of refraction n=c/v n should always be >1 (because c is light) n shows the density of medium that is more dense than air
Describe the Yerkes-Dodson Law
Describes social facilitation optimal performance is associated with an intermediate level of arousal
What is identity?
Descriptive characteristics, qualities, and abilities that make a person unique or different relative to others, in relation to social context A combination of self-identities and group identities How i am defined by myself, others, and in various situations; Who i am
Detection bias vs performance bias vs experimenter bias
Detection= differences caused by inconsistency in detection or diagnosis Performance= differences in terms of care or treatment provided Experimenter= errors caused by expectations of investigation
Difference between displacement and distance
Displacement is path independent. The shortest distance between points A and B. Vector from start to end. Displacement can also be seen as the area under velocity vs time graph Distance is path dependent. A measurement of travel along any path, curved, linear A car drives around in a circle: Distance=X ; Displacement=0
Somatic vs Autonomic
Divisions of the peripheral nervous system Somatic: voluntary control; innervates skeletal muscle; contains both sensory and motor subdivisions Autonomic: involuntary control; innervates cardiac, smooth, and glands; contains both sensory and motor subdivisions
What are catecholamines
Dopamine, epinephrine, norepinephrine Dopamine is a CNS neurotransmitter Epi and Norepi are two metabolic hormones for carbohydrates; has a glucagon-like effect but causes more rapid mobilization of energy stores
What is Echolalia and Echopraxia?
Echolalia= individual automatically repeats anything that is said by others Echopraxia= imitate any movements made by others
Efferent vs Afferent vs Interneurons
Efferent: motor neurons; carry signals to a muscle or gland to respond to the stimulus Afferent: sensory neurons; receive signals from sensory cells Interneurons: connect afferent and efferent neurons. Transfer and process signals. The brain and 90% of all other neurons are interneurons
What is reserve volume
Either inspiratory reserve volume (IRV) or expiratory reserve volume (ERV) the volume of additional air that can be exhaled or inhaled after a normal unforced exhalation or inhalation
What are the 2 kinds of synapse? Describe them
Electrical: gap junctions between cells allow electrical signal to pass quickly from cell to cell. In humans they are found in retina, smooth muscle, cardiac muscle, and CNS Chemical: small gap between the terminal button and either 1.) Dendrite of subsequent neuron or 2.) Membrane of muscle or other effector
Periodic trends of Electron Affinity, Ionization Energy, Electronegativity, atomic radius, and metallic character
Electron affinity, ionization energy, electronegativity increase up and to the right Atomic radius and metallic character increase down and to the left
Electron withdrawing/donating effect on basicity
Electron donating= higher basicity Electron withdrawing= lower basicity
What is the endocrine function of the pancreas? Exocrine?
Endocrine: insulin and glucagon secretion Exocrine: digestive enzyme secretion
What is chemical energy
Energy contained within chemical bonds, or energy stored/released due to separation and/or flow of electrons Battery
What is the law of conservations of energy
Energy in an isolated system is always conserved Energy can be transferred back and forth between forms, but is never lost
Episodic memory (examples) vs Semantic memory
Episodic: Memory of autobiographical (self world) events; times, places, emotions Semantic: General world knowledge accumulated through our lives
What do exocrine glands do vs endocrine glands
Exocrine: release enzymes or other liquids into the external environment (including digestive tract and epithelial-lined orifices; substances released are sweat, oil, mucus, and digestive enzymes) Endocrine: release hormones into internal fluids of body (blood, lymph, etc)
Explicit memory vs Implicit Memory
Explicit: AKA Declarative; requires conscious, intentional recall Implicit: AKA Non-declarative; procedural type memories like riding a bike
Effects of external and internal locus of control
External: low-self esteem, depressed Internal: happier and higher self esteem
Bundle of His
F
Schwann Cell
F
What is the universal law of gravitation
F=Gm₁m₂/r² This is true everywhere in the universe
Hydraulic lift machine equation
F=mg(h₁/h₂) or F=mg(A₂/A₁) h₁=distance traveled by large plunger h₂=small plunger A₁=cross sectional area of large plunger A₂=small plunger
Force and normal force down an incline plane
F=mgsinθ Fn=mgcosθ
Newton's 2nd Law
F_net = ma A constant force will cause a constant acceleration, NOT increasing acceleration. Velocity will increase faster and faster, but acceleration won't You CANNOT accelerate a ball across the room by throwing it, to accelerate you must be in contact with the object creating force
Confabulation
Fabrication of false, but usually vivid and detailed memories to fill in the gaps in a coherent story or memory Often seen in Alzheimer's disease or Karsakoff's syndrome
Describe family, adoption, and twin studies in relation to nature vs nurture study methods
Family: compare the frequency of behavior/condition/trait among related individuals to the frequency of that same measure among non-relatives Adoption: compare the behaviors/conditions/traits of an adopted child to those of its adoptive parents; simultaneously compare that same child, on those same measures, to its biological parents Twin: compare concordance rates between monozygotic twins raised in the same family to dizygotic twins raised in the same family; or compare concordance rates for monozygotic twins raised in the same family to those raised apart
Absolute configuration of amino acids
Fischer projection (L=Left; D=Right) All native human amino acids have L-configuration All are S enantiomers except glycine (not a steroeocenter) and Cysteine (sulfur makes it R)
Fixed ratio vs fixed interval vs variable ratio vs variable interval
Fixed ratio: worker is paid every time he finishes a project Fixed interval: worker is paid every Friday Variable ratio: worker is paid after a various number of finished projects Variable interval: worker is paid at variable times
Describe Alpha Helices
Formed by a hydrogen between carbonyl oxygen and amide-hydrogens that are 4 residues apart A-B-B-A: the A's will share a H bond R groups are directed away from the helix core Keratin (hair and nails) is an example
Acetylcholine (found where, primary regulatory functions, and any correlates to disease or psych disorder)
Found in both CNS and PNS In CNS, acetylcholine is involved in both arousal and attention. Depletion of acetylcholine is associated with memory deficits that characterize Alzheimers In PNS, acetylcholine is the primary neurotransmitter of the neuromuscular junction and is found in both the sympathetic and parasympathetic system divisions of autonomic nervous system
Gem-/Vic-
Geminal=on the same atom Vicinal=on adjacent atoms
What is a gene? What is an allele?
Gene: segment of DNA that codes for a protein Allele: one of various alternative forms of the same gene
Generalization vs discrimination in classical conditioning
Generalization= tendency to respond in the same way to different but similar stimulus Discrimination= ability to perceive and respond to differences in stimuli
Describe population and it's relationship to industrialization and modernization
Generally population is inversely related to industrialization and modernization.
Describe Mendel's Law of Independent Assortment
Genes located on different chromosomes assort independently
Describe liver specific metabolism
Glucose in well-fed state; fatty acids during fasting; NO ketones used
What is the Hawk-Dove game?
Hawk Strategy: Fight until you are injured or the opponent gives up the resource. If battling a dove, always win; if battling another hawk will only win half of the time Dove Strategy: Act as though you are going to fight, but you will give up if the opponent attacks. If battling a hawk, will lose every time; if encountering another dove, they will split the resources
Functionality of hydrophobic/hydrophilic R groups
Hydrophobic R groups fold into the protein core Hydrophilic R groups are more common on the surface of proteins
What are the three major perspective on globalization (and describe)
Hyperglobalization perspective=globalization is a major new epoch in human history, national boundaries will be dissolved. Will ultimately cause economic logic of a global economy Skeptical Perspective=current globalization is fragmented and regionalized. The peak of globalization occurred in the 19th century and nationalism is now on the rise. Ultimately says that globalization isn't really occurring Transformationalist perspective= globalization may be occurring, but the degree to which it is, and its eventual outcomes is undetermined. There is not single cause for this
Hypertonic vs hypotonic cells
Hypertonic: cell is more concentrated, so water leaves the cell Hypotonic: cell is less concentrated, so water enters the cell
Describe the work-energy theorem
If a net force does work on a rigid object, work done on that object is equal to the change in kinetic energy of the object W=KE(final)-KE(initial)
Role of renin/angiotensin pathway in kidneys
If there is low BP, then the Juxtaglomerular apparatus detects and secretes Renin. This will set into motion the Renin-angiotensin pathway which increases blood volume and blood pressure Angiotensin also stimulates aldosterone release from adrenal cortex gland which will cause reabsorption of of Na and Cl, excretion of K, and water retention
Describe the phases of the cell cycle
In order: G1: first growth phase. Where most active cells live and function. Considerable growth S: DNA is replicated G2: continued cell growth and higher metabolic activity. Especially high production of microtubules for M phase G0: Coincides with G1 phase. The "non-proliferative" or "rest" phase. Home of fully differentiated neurons and cardiac muscle cells. M: mitosis phase Then back into G1. G1, S, G2, and G0 are all part of interphase
Describe how a photon is released
In the Bohr model, when a electron relaxes from higher, excited state to it's lower, ground state
Describe how to increase capacitance
Increase plate area, decrease distance Increase plate thickness will have no effect on capacitance because charge is stored on the edges of the plate
Independent vs Dependent variable
Independent-thing that is being manipulated and directly changed by investigator. Thought of as the "cause". Always on x-axis Dependent-variable measured as response to changes in the independent variable. "Effect" variable. Always on the y-axis
Describe the basic diagnostic symptoms of Schizophrenia
Individual must exhibit for at least one month two or more of the symptoms: hallucinations, delusions, disorganized speech, grossly abnormal psychomotor behavior, and negative symptoms; at least one of them has to be a positive symptom Have experienced significant impairments in ability to engage in day to day activities and in interpersonal relationships as a function of the onset of symptoms Alternative diagnoses have been ruled out (schizoaffective and mood disorders) Symptoms are not better explained by substances and/or other medical conditions Individuals with autism or another pervasive developmental disorder must present with prominent delusions or hallucinations for at least one month
Two theories of enzyme-substrate specificity
Induced fit: as the substrate binds, the affinity for the substrate increases (favored theory) Lock and key: active site is an exact fit for substrate. Unfavored because it is very rigid and inflexible active site
What is inductive reasoning vs deductive reasoning
Inductive= making generalizations from specific observations (bottom-up) Deductive= conclusions are based on assumed premises (top-down)
Newton's First Law
Inertia: an object in motion tends to stay in motion, an object at rest tends to stay at rest; unless acted on by a net external force
Describe a competitive inhibitor and the graphs associated
Inhibitor binds at the active site Vmax will not change Km will increase
Describe noncompetitive inhibitors and their graphs
Inhibitor binds away from the active site Vmax decreases Km doesn't change
Describe uncompetitive inhibitors and their graphs
Inhibitor binds only the enzyme substrate complex Vmax and Km decrease
Describe an uncompetitive inhibitor, its effects on variables, and an example
Inhibitor that binds ONLY w/ the enzyme substrate complex, not the active site. Uncommon because the time window is very small to bind before converted to product Vmax= decrease Km=decrease Lithium (manic depression) acts on phosphoinositide synthesis pathway, inhibiting inositol monophosphates and preventing inositol recycling in the brian
Describe a non-competitive inhibitor, its effects on variables, and an example
Inhibitor that binds away from the active site. Changes the shape of the enzyme. Has an equal affinity for both the E-S complex and just the enzyme Vmax=decrease Km=no change Alanine acts as non-competitive for pyruvate kinase enzyme. Alanine will bind to pyruvate kinase and prevent transfer of phosphate group from PEP to ADP
Describe a mixed inhibitor, its effects on variables, and an example
Inhibitor that has unequal affinity for E-S and the E, and favors one over the other. Mix of non-competitive and uncompetitive Vmax=decrease Km= (increase if higher affinity for E) (decrease if higher affinity for E-S) Palladium is mixed inhibitor for xanthine oxidase (enzyme that converts xanthine to uric acid)
Innate behavior vs learned behavior
Innate behavior is thought to be predominantly genetic and present regardless of environmental influences Learned behavior is thought to be predominantly environmental (learned via experience), and independent of heredity
Describe insomnia and sleep apnea
Insomnia=difficulty falling asleep or staying asleep Sleep apnea=difficulty breathing while asleep
Instinct vs arousal theory of motivation
Instinct= behavior is motivated by evolutionary instincts (migration) Arousal= behavior is motivated by desire to maintain an optimum level of physiological arousal. That optimum level varies among individuals. People will seek new interests, action, or stimuli when arousal is low to increase arousal. When hyper-stimulated, they seek to reduce with relaxation
Why is insulin released and what happens?
Insulin is released in response to high glucose levels. Insulin will stimulate glycogenesis in the liver, as well as the uptake of glucose from blood into cells
Difference between Jung's Cognitive Processes and Myer's-Briggs personality types
Jung's works with 3 sets of dichotomies: Extrovert vs Introvert, Sensing vs Intuition, and Thinking vs Feeling Myer's Briggs uses all 3 of these but adds a 4th: Judging vs Perceiving
Differences between Jung and Freud on Ego
Jung= Ego is the conscious mind only Freud= Ego is conscious, preconscious, and unconscious
Differences between Jung and Freud on unconscious?
Jung= unconscious is the storage place of repressed memories, both good and bad. Ego is not part of the conscious mind, it is 100% unconscious. There are two subdivisions of the unconscious: personal unconscious and collective unconscious Freud= unconscious is the storage place of unacceptable, repressed desires. Parts of the Ego and Superego are unconscious, as is all of the Id
What is hyperpolarization
K+ channels are somewhat slow to close as membrane potential approaches -70mV; so membrane potential actually dips to around -90mV before gradually returning to resting potential
Kinetic energy vs gravitational potential energy equation
KE=¹/₂mv² PE=-Gm₁m₂/r or PE=mgh Joules
Ketogenic vs Glucogenic AA synthesis
Ketogenic= degraded into acetyl-CoA or acetoacetyl CoA through ketogenesis. Their carbons are ultimately converted to CO₂ in the citric acid cycle. LEUCINE and LYSINE do only this Glucogenic= can be converted to glucose through gluconeogenesis. Are first converted to alpha keto acids and then to glucose in the liver. Isoleucine, Phenylalanine, Tryptophan, Tyrosine, and Threonine are BOTH ketogenic and glucogenic. The rest are just glucogenic
Kinesthetic sense vs vestibular sense
Kinesthetic: body position and movement of body parts relative to one another Vestibular: balance and orientations by responding to changes in linear and rotational acceleration detected by hair cells in vestibule and semicircular nerve
Classification levels in taxonomy (what are humans in)
Kingdom, Phylum, Class, Order, Family, Genus, Species Humans= Animalia, Chordata, Mammalia, Primates, Hominidae, Homo, Homo sapiens
What is the solubility product constant? How do you calculate? How do you change it
Ksp This can only be observed in saturated solutions. Leave out pure liquids and pure solids in calculations. Temperature is the only thing that can change the Ksp.
Systemic circulation
Left ventricle --> arteries --> arterioles --> capillaries --> venules --> veins --> vena cava --> right atrium
Lipid vs peptide hormones action at target
Lipid-soluble: act almost exclusively by binding to a receptor on or inside the nucleus and influencing transcription Peptide hormones: act at a variety of cell locations
Lipid vs peptide hormones on membrane permeability
Lipid-soluble: diffuse easily through lipid center of membrane and thus do NOT require a cell membrane receptor. They do require a receptor wherever they act inside the cell though. Peptide hormones: are hydrophilic and can't dissolve through the membrane, thus they require a membrane receptor
Lipid vs peptide hormone transport
Lipid-soluble: require a protein carrier or a micelle/vesicle Peptide hormones: are water-soluble and dissolve in blood readily
Sounds heard by the cochlea and where
Low frequency and low pitch are heard at the apex of the cochlea High frequency and high pitch are heard at the base of the cochlea
Aliphatic
Meaning "non-aromatic"
What is the difference between medical model of disability and social model of disability?
Medical model: Sees the illness or impairment as the problem. The illness or disability is the target of cure and individuals are the passive receivers of services. Diagnosis and treatment is the primary approach Social model: sees the structures within society as the problem. The ill or people with disability are active participants working in partnership with others. Prevention and integration are the primary approach rather than treatment. This approach benefits everyone and pushes society to evolve.
Superior Colliculi (subdivision, embryological origin, and function)
Midbrain from the mesencephalon controls visual motor reflexes
Manganate
MnO₄²⁻
Permanganate
MnO₄⁻
Morbidity vs mortality
Morbidity is another name for illness. Prevalence is a measure used to determine the level of morbidity in the population. Mortality is another name for death. Mortality rate is the number of deaths caused by a disease divided by the total population.
Describe protein metabolism
Most amino acids can be broken down into either pyruvate of acetyl-CoA and fed into the citric acid cycle. Others than can't can be transformed into various citric acid cycle intermediates and enter the cycle at appropriate points
Frontal lobe is responsible for
Motor control Smell Speech Concentration, planning, problem solving
Describe the basic diagnostic symptoms of obsessive compulsive disorder (DSM)
Must exhibit obsessions and or compulsions Obsessions= repeated occurrence of unwanted thoughts which generate significant anxiety such that the individual experiencing them will try to make these thoughts stop Compulsions= repeated patterns of behaviors or thoughts that the individual engages in to make the obsessions go away The purpose of these ritualized patterns is to reduce stress or avoid some feared situation. They are time consuming and represent a significant impairment to the individuals daily activities
What is mutualism? Commensalism? Parasitism?
Mutualism= symbiosis where both participants benefit equally Commensalism= symbiosis in which one participant benefits and the other is neutral Parasitism= symbiosis where one participant benefits at the expense of the other
Describe the structure of myosin
Myosin filaments=bundle of individual myosin molecules Each myosin has globular head, which binds to actin filaments to form "myosin cross-bridges" responsible for actual contractile mechanism Default, low-energy position of myosin heads is bent
What is the role of myosin in muscles
Myosin has 2 moieties (globular head and a tail) Two fibers intertwine to make up a myosin molecule (a dimer) Heads protrude from the myosin filament at an angle in relaxed conformation ("Bent" sliding filament model) Heads have a high affinity for actin and bind it unless binding sites are blocked by tropomyosin
How to find the pI of a neutral, acidic, and basic amino acid
N: pI= pKa(Amine) + pKa (Carboxyl) /2 A: pI=pKa (acidic R) + pKa (Carboxyl) /2 B: pI= pKa (Amine) + pKa (basic R) /2
Describe the malate-aspartate shuttle and why it's used
NADH cannot pass through the inner mitochondrial membrane, so NADH donates two of it's electrons to oxaloacetate, converting it to malate. Malate will then pass into the mitochondrial matrix via the malate-α-ketoglutarate antiporter and is converted back into oxaloacetate inside, releasing NADH
Describe the flow of NADH and FADH2 in the ETC
NADH will yield 3 ATP each. NADH flows through complexes I, III, and IV; pumping 4, 4, and 2 electrons FADH2 will yield 2 ATP each. FADH2 flows through complexes II, III, and IV; generating 0, 4, and 2 electrons each (complex II doesn't pump electrons because it doesn't span the entire membrane)
Name some of the common electron carrier molecules/redox reaction molecules in biological systems
NADH/NAD+ FADH2/FAD NADPH/NADP+ FMNH2/FMN semiquinone ubiquinone cytochrome
Ammonia
NH₃
Describe charge by induction
Negative material approaches a neutral material, and the neutral material orients it's negative charges away and positive charges toward. Then set up a grounding source to allow the negative charge to leave and cut the ground wire first, leaving with second material having a net (+) charge
Describe the characteristics of saturated triglycerides
No double bonds. Are usually very straight. Solid at RT because they have a higher MP Unhealthy (often associated with cardiovascular disease) because they are stored more easily Higher energy required to metabolize (generate more calories). Often come in handy in times of famine
Describe electromagnetic waves
No medium is required, capable of propagating in a vacuum. They transfer energy and momentum through space Includes visible light, microwaves, radiowaves, etc Are only transverse waves
Describe an SN1 reaction and the qualities around it
Nucleophilic substitution, first order 2 steps: dissociation of leaving group (slow); attack of carbocation by nucleophile (fast) Favored by poor nucleophiles, tertiary carbons, and polar protic solvents
Describe an SN2 reaction and the qualities around it
Nucleophilic substitution, second order single-step, backside attack of electrophile with simultaneous ejection of leaving group favored by good nucleophiles and primary or secondary carbons
What is the difference between an obligate and a facultative aerobe? Obligate vs facultative anaerobe?
Obligate: there is no other option. So obligate aerobes must use oxygen for respiration and cannot survive without. Facultative implies that the organism will use whichever respiration is available
What is an Oedipal complex? Castration anxiety? Penis Envy?
Oedipal: boy secretly wants to kill father and posses mother as own Castration: boy fears stronger father in Oedipal complex and challenging may result in castration, so boy identifies with father in a way to possess the mother vicariously Penis envy= same as above but for daughters to fathers
What are hallucinations?
Often a marker for schizophrenia Often auditory in nature
What is positive feedback in relation to the menstrual cycle
On approximately day 14, high estrogen levels stimulate a rapid increase in LH. This increase in LH is a good example of positive feedback
What is an open system? Closed system? Isolated system?
Open=both mass and energy can be exchanged with the surroundings Closed=energy, but not mass can be exchanged Isolated= neither mass nor energy can be exchanged
Describe Freud's Superego
Operates in the conscious, PRE-conscious, and Unconscious Responsible for judging action based on internalized moral standards obtained from parents and society. Often called the "perfectionist" portion of Freud's personality theory. Further suppresses impulses of the Id and influences the Ego to be more idealistic than realistic Develops around age five
Parts of the outer ear Parts of middle ear Parts of inner ear
Outer: pinna (earlobe) and auditory canal Middle: tympanic membrane (eardrum), and three middle ear bones malleus, incus, stapes Inner: cochlea, vestibule, semicircular canals, and vestibulocochlear nerve
Electrical potential energy equation
PE=kq₁q₂/r or PE=qEd or PE=qV k=9x10⁹ Nm²/C²
Phosphate
PO₄³⁻
Hormones released by parathyroid (characteristics)
PTH (parathyroid hormone) Are peptides and water-soluble
What is the ideal gas law, and what are the constant values
PV=nRT R=0.0821 L×atm/mol×K R=8.314 J/mol*K Follows the ideal gas assumptions
Glucagon: location, class, function
Pancreas peptide/water-soluble stimulates gluconeogenesis and release of glucose into the blood
What are the biological markers of Parkinson's disease?
Parkinson's is a neurodegenerative disease characterized by slow, halting movements, tremors, muscle rigidity, and a shuffling gait. Dementia and language difficulties are common, but not always present Decreased stimulation of the motor cortex by the basal ganglia due to a decrease in dopamine production by the substantia nigra. Basal ganglia is responsible for producing smooth motor movements. Parkinson's is often treated with L-Dopa, direct precursor for dopamine. Direct treatment with dopamine cannot pass the blood brain barrier
What is exchange theory?
People act rationally to get what they need by exchanging goods and services with others. Relationships continue with others based on a simple calculation of rewards minus costs equals outcome. If the outcome is neutral or positive, then the relationship is likely to continue. If the outcome is negative then this theory says that this relationship is likely to end.
Describe voltage
Potential energy per unit change (V=PE/q) Can multiply by charge to get potential energy volt=J/C
What is the serial position effect and how do the primacy effect and recency effect play in?
Presentation order, or positioning list impacts recall Primacy: first few concepts will be remembered at higher rate Recency: last few concepts will be remembered at higher rate
Pi bond characteristics and what it looks like
Prevents rotation, weaker, less stable, more reactive (than sigma) side to side overlap of 2 p orbitals As radius of either atom increases, the p orbitals are spread apart and the pi bond is weaker (C=N is weaker than C=O)
What is the primacy effect vs recency effect
Primacy is that we recall the first few items in a list more readily than other items Recency is recall of the most recent items in a list better than others
Primary/Conditioned Reinforcement/Punishment in Operant Conditioning
Primary Reinforcement= biological (drink, food, pleasure) Primary Punishment= punishment that is unpleasant (physical pain or discomfort) Conditioned Reinforcement (Secondary)= stimuli, objects or events associated with primary reinforcement Conditioned Punishment (Secondary)= stimuli that is associated with primary punishment
What is a primary group vs a secondary group
Primary=long-lasting, close interactions, tight bonds, and unlikely to dissolve Secondary=short-lived, superficial, weak bonds. Dissolve easily
What is primary socialization? Secondary socialization?
Primary=the most influential form of socialization. The most intense and has the longest term effects. Family (parents, siblings, spouse, children Secondary=wide variety of agents. Influential, but not as much as primary. Peer groups, eduction, mass media, religion
2 approaches for managing stress?
Problem solving approach: find solutions, obtain help, stress prevention plan, etc Emotional approach: change how you feel about the stressor through positive thinking, taking personal responsibility, internal locus of control, etc Proven tools for stress management= exercise, relaxation, spirituality
What is social reproduction
Process through which entire societies and their cultural, structural, and ecological characteristics are reproduced. Includes economic institutions, religious institutions, language, varieties of music, and other cultural products
Type A vs Type B personality
Proposed by 2 cardiologists to predict one's likelihood of developing CAD. Type A: Competitiveness, time-urgency, hostility Type B: More relaxed and reflective; lower anxiety levels and higher imagination/creativity
What are the 3 embryological regions of the brain and what do each of them give rise to?
Prosencephalon (gives rise to the telencephalon and diencephalon) Mesencephalon Rhombencephalon (gives rise to the metencephalon and myelencephalon)
Psychoanalytical vs Humanistic perspectives
Psychoanalytical: Patients are "sick", repressed, or have other troubles in need of treatment. A person is DEFINED by their neuroses Humanistic: How healthy individuals strive toward self-realization; HOLISTIC view of the person, as more than the sum of their neuroses
Describe Bernoulli's Equation
P₁+pv₁²+pgh₁=P₂+pv₂²+pgh₂ Pressure + the kinetic energy (density times volume squared) + potential energy (density gravity height) is same on both sides of system Applies to both gases and liquids
Flow rate equation
Q=AV (A=total cross-sectional area; V=velocity) Often used for flow across cardiovascular system
What is absolute configuration
R and S (distinguish enantiomers) assign priority by molecular weight, with the lowest priority in the back R=Clockwise S=Counterclockwise
Resistor, Capacitor and battery in series
R=R₁+R₂+R₃ 1/C=1/C₁+1/C₂+1/C₃ Battery: add voltage, but not capacitance
Describe the differences between Galvanic, Electrolytic, and Concentration cells
RED CAT AN OX for Galvanic and Electrolytic cells In Galvanic cells, reduction will occur at the cathode. The port with the higher Eo will be the cathode In Electrolytic cells, reduction will occur at the cathode. The port with the lower Eo will be the cathode. This will always have a NET -E value Concentration cells will use the same metal in both beakers, but in different concentrations. The electrons will go from the smaller concentration to the larger concentration to have a balance. Follow OIL RIG for RED CAT AN OX, not Eo values
Differences between RNA and DNA
RNA has a 2' hydroxyl group, DNA doesn't RNA is normally single-strands, DNA is double RNA contains uracil bases instead of thymine RNA exits the nucleus into the cytoplasm; DNA always stays in the nucleus
What is the absorbance range of an H-NMR and what does the location of the peaks on the graph signal
Range is 0-12ppm. 12ppm is downfield/deshielded. If a peak is more downfield, then it has more stuff surrounding it (ie CH3Cl) 0ppm is upfield/shielded. If a peak is more upfield, then it has less stuff surrounding it (ie CH4) 0ppm is TMS, baseline.
What did Raymond Cattell do?
Ranked large sample on 171 character traits, and used factor analysis to reduce this to 16 traits Resulting in 16-personality factor questionnaire is widely used
What is Graham's Law?
Rate of effusion for first gas÷ second gas
Describe the decibel system and how to calculate
Rating system for intensity of sound within range of human hearing. Is similar to richter scale for earthquakes Intensity=10*log(I/I₀) (I₀=threshold for human hearing) 10x sound increase=10 decibel increase; 100x sound increase=20 decibel increase
What are the differences between real gases and ideal gases?
Real gases will differ the most from ideal gases when: 1. temperatures are extremely low (interaction between gas molecules is lower and produces smaller pressure than predict by ideal) 2. Pressure is extremely high (gas molecules occupy greater volumes)
What determines a cathode/anode
Reduction happens at the cathode Oxidation happens at the anode
Describe some of the ways to improve extraction (repetition, fractional, acid/base addition)
Repetition is used because very rarely is full separation obtained after just one cycle Fractional extraction is more efficient because extraction with 5mL 10 separate times is better than separating with 50mL once Addition of an acid or base to protonate/deprotonate products makes them more charged and thus would be more soluble in the aqueous layer
Order of Erickson' psychosocial development
0-1.5: Trust vs Mistrust 1.5-3: Autonomy vs shame 3-5: Initiative vs Guilt 5-12: Industry vs inferiority 12-18: Identity vs confusion 18-40: Intimacy vs isolation 40-65: Generativity vs Stagnation 65+: Integrity vs despair
glomerular capsule (bowman's capsule)
1
renal medulla
1
superior vena cava
1
superior vena cava opening
1
pulmonary artery
2 and 10
coronary sinus opening
4
descending limb of loop of Henle
4
pulmonary trunk
4
renal capsule
4
What is Field Theory?
Kurt Lewin Focuses on the state of mind of the patient as the sum of interactions between their individual personality and the total field (their environment)
Potential energy stored in a capacitor equation
PE=1/2CV²
What is a reducing sugar?
a sugar capable of of reducing another molecule. The sugar will then become oxidized Has to have a free aldose group (an R-OH on only one side of the ring oxygen). Can potentially be a ketose sugar, but it has to be able to isomerize to contain an aldehyde
What is the looking-glass self?
a theory suggesting that a person's self-concept is largely determined by how they believe others see them. Not what we are, but what we think we are
What is conversion disorder
characterized by the "conversion" of psychological stress into actual neurological deficits; usually numbness, paralysis, or blindness.
What is the Hawthorne effect
a study's results are affected by participant's knowledge that they are taking part in an experience or being treated differently than usual
What is rRNA
polymer of which ribosomes are constructed. Assembled in nucleolus. Ribosomes are a non-protein entity that act as enzymes in polymerization of proteins.
Automatic spreading activation
primer is a category name and target is an example within that category
Correlation coefficient
r² measure of how tightly data from "best fit line" fits 0 to 1.0 --> the closer the data is to the best fit line, the closer to 1 the r² value 1.0=perfect correlation
Function of proximal convoluted tubule
sodium reabsorption via secondary active transport. Filtrate will remain isotonic here because water and solutes are reabsorbed at the same rate
What is a diastereomer (3 kinds)
has the same formula, bonds, etc Is non-identical, non-superimposable, NOT mirror images Geometric isomers, epimers, anomers
Define amphipathic (which of the lipids would be so)
having both hydrophilic and hydrophobic parts fatty acid, phospholipid, sphingolipid, and glycolipid
Define amphipathic
having both hydrophilic and hydrophobic regions
Describe lactic acid fermentation
lactate is produced and is the final electron acceptor when oxygen isn't present This is important because NAD+ is regenerated again so that glycolysis can continue
Name the common disaccharides
lactose= galactose + glucose (β-linked) maltose= glucose + glucose sucrose= glucose + fructose
What is a beta linked carbohydrate?
linked through an oxygen atom on the SAME side of the plane
What are prostaglandins?
lipid mediators that have autocrine (self-target) and paracrine (target=cell in immediate vicinity) functions throughout the body HORMONE LIKE EFFECTS Produce and released throughout body, NOT just in specialized glands (like endocrine) Act locally, rather than traveling to distant targets via bloodstream (like endocrine)
What are the 3 primary contributors to the cytoskeleton of the cell
microfilament, intermediate filaments, and microtubules
What is mole fraction
moles solute/total moles of solution
Describe anxiety disorder frequencies
more frequent among women than men. Most common psychological disorders in the US
What is a phosphatid
most basic phospholipid 2 fatty acids and ONLY a phosphate group attached directly to a glycerol backbone
What are proto-oncogenes?
normal versions of oncogenes. They encode for proteins that stimulate normal cell growth & division. Usually regulate cell-growth, division, apoptosis, etc as their normal function
What is anomie
normlessness. a state of instability due to lack of social norms or breakdown of social standards or values Individuals in a state of anomie lack purpose and feel a sense of futility because acceptable goals or ideals are unclear
What are mores
norms that have moral significance and are widely observed by members of society (driving a care while drunk=violation of more)
What is hydration number
number of water molecules an ion can bind via solvation process
Lateral geniculate nucleus (LGN)
part of the thalamus; relay center between the optic nerve and the visual cortex of the occipital lobe
∆H(vaporization)
phase change from liquid to gas; the reverse process is called condensation
Role of bones
physical support and movement, protection of vital structure, mineral storage and regulation of blood mineral concentration and blood cell formation
What are recognition sequences
specific base sequences recognized by endonucleases
Describe Km
the Michaelis constant Km= [S] at 1/2 vmax Magnitude is inversely proportional to substrate-enzyme binding affinity A lower Km= stronger binding affinity
Sensory memory
the ability to retain impressions of sensory info after original stimuli has ended; it is stored just long enough to be transferred to short term memory
What is primary protein structure
the amino acid sequence
Define socialization
the lifelong process beginning in infancy, by which an individual acquires the habits, norms, and beliefs of society Also includes the ways in which society disseminates skills, knowledge, and behaviors
Describe the activation synthesis theory of dreaming
the limbic system is randomly active during sleep, mimicking incoming stimuli. Dreams are an attempt by the cerebral cortex to synthesize and interpret this activity in a logical way
What are sister chromatids
two strands of DNA in duplicated chromosomes attached by a centromere
What is attribute substitution
when faced with a complex mental task or judgment, we tend to substitute to a more simple scenario of problem This includes visual shortcuts that cause us to misinterpret an optical illusion
Embryology stages
-Cleavage=(mitosis without change in size) - Morula= 8-celled zygote - Gastrulation= at about week 2, cells migrate to form 3 germ layers - Neurulation= at about week 3, the notochord forms from mesoderm and induces the overlaying ectoderm to form the neural plate, which becomes neural tube and eventually the spinal cord
What are the 5 mechanisms for choosing a mate
-Direct phenotypic benefits -sensory bias (more choosy sex prefers certain characteristics) -Fisherian runaway hypothesis (peacocking) -Indicator traits (good overall qualities of individual) -Genetic compatibility
right pulmonary veins
20
Sp3d shapes (picture) and angles
90/120 or 180
What is genetic drift?
A change in allele frequencies caused by random events
What are the elemental symbols
A=Mass number; number of protons and neutrons Z=atomic number; number of protons
Area of a circle equation
A=πr²
Bowman's capsule
B
Describe the oxidation of a tertiary alcohol
Cannot be oxidized
What kind of peak is seen at 1700cm-1 on IR?
Carbonyl (C=O) bond. Sharp and deep
γ-Aminobutyric acid (GABA) (found where, primary regulatory functions, and any correlates to disease or psych disorder)
Chief inhibitory neurotransmitter of the CNS
Hypochlorite
ClO⁻
Electric potential energy equation
Constant electric field: PE=qEd (charge)(field)(distance) (PE=mgh) Point charge: PE=kq₁q₂/r (attractive if opposite, repulsive if like)
Voltage equation
Constant field: V=Ed (field)(distance) (V=gh) Point charge: V=kq/r
Converging vs diverging lens
Converging (convex, positive) usually produces PRI When object is inside the focal point it produces NVU Diverging (concave, negative)=always produces NVU
Lens of human eye has what lens and image
Converging lens and produces positive, real, inverted (PRI) image
Culture and evolution
Culture speeds up human evolution. Cultural change most directly drives evolution. The more dramatic the change, the more likely that change is to speed up evolution
What is the basic model of emotional expression (who)?
Darwin emotional expression is universal and expressed in similar ways across cultures
Right Bundle Branch
E
Terminal Button
E
What is the Nernst Equation? How is it used
E=E°-(0.06/n)×log[Lower]/[Higher] n=# of moles of electrons transferred Used for concentration cells. E° is always 0 for concentration cells
Describe the differences between exergonic and endergonic
Exergonic reactions are spontaneous and their ∆G is negative Endergonic reactions are non-spontaneous and their ∆G is positive
Exocrine vs excretory system
Exocrine= sebaceous or oil glands Excretory=kidneys
Where are noble gases on periodic table
Group 18
2nd Law of Thermodynamics
Heat can't be changed completely into work in a cyclical process Entropy in an isolated system can never decrease
Illness vs Disease
Illness= a person's subjective experience of a health problem Disease= a medical professional's scientific definition of a health problem based on signs and symptoms
Wavelength order (from low energy to higher energy)
Infrared-->ROYGBIV-->UV
Nearsightedness vs Farsightedness
Near (myopia): elongation or severe curvature of cornea, so image focuses too early. It is more difficult seeing things at a distance Far: eye is too short or the cornea doesn't curve enough. Difficult seeing things that are clsoe
Characteristics of granulocytes
Neutrophils, basophils, and eosinophils -Basophils are stained dark blue (due to basic nature) -Eosinophils are stained bright red (due to acidic nature) -Neutrophils are stained a "neutral" pale pink color They are called granulocytes because of appearance on light microscope when stained because they contain large cellular granules All are short lived, do NOT reside permanently in tissues, circulate in blood, and are recruited to areas of infection and inflammation
Granulocyte roles
Neutrophils: Common Basophils: Allergies, histamine Eosinophils: Parasites North Carolina Basketball Always Has Extra Players
Path of a photon into eye
Photon → Cornea → Aqueous Humor → Pupil → Lens → Vitreous Humor → Retina
What does polygenic mean? Pleiotropy?
Polygenic= When many genes contribute to one phenotypic trait? Pleiotropy= when once single gene contributes to multiple phenotypic traits
7 types of retrieval cues
Priming effect, Typicality Effect, Familiarity Effect, True-False Effect, Category Size Effect, Serial-Position Effect, Interference Effect
Goal of Punishments vs Reinforcements
Punishments DECREASE frequency and weaken behavioral response Reinforcements INCREASE frequency of behavior and strengthen response
3 types of retrieval
Recall: retrieval and active statement of, or correct application of, a memory Recognition: associating information with an existing memory (Re-cognition) Relearning: increased learning efficiency when reinforcing an existing memory
Where are non-metals on periodic table
Right side of the staircase starting with Boron
Sympathetic vs parasympathetic NS on BP and HR
SNS increases HR and BP PNS decreases HR and BP
Memory storage effect on plasticity (LTP vs LTD)
STM may result from temporary chemical or electrical traces that fade quickly. LTM traces are always the result of physical changes to the neuron itself LTP (long-term potential): persistent strengthening of a synapse based on increased activity at that synapse LTD (long-term depression): persistent weakening of a synapse based on decreased activity. Theoretical opposite of LTP
Describe feedback inhibition
Same as negative feedback product of a reaction acts as an antagonist for the reaction
What is the difference between social class and socioeconomic status
Social class is the separation of a society into hierarchical classes or divisions Socioeconomic status is indicated by occupational prestige, educational attainment, income and wealth
Describe class differences and healthcare disparities
Socioeconomic class is strongly correlated with overall health, access to healthcare, and healthy behaviors both in the US and worldwide The poorest people are the most sick, are more susceptible to disease and disease outbreaks, have less access to healthcare, and engage in more unhealthy behaviors at a much higher rate
What is Henry's Law?
Solubility of a gas in a liquid is directly proportional to the partial pressure of that gas over that liquid
Velocity equation
V=√2gh or V=√2ax
What is a zymogen
an inactive enzyme precursor. Often activated for something that is needed very quickly. Would be detrimental if it were active all the time Prothrombin: activated by prothrombinase which converts prothrombin to thrombin, a vital enzyme in blood coaglution
What is the halo-effect
bias by which positive appraisal, in one area will automatically generate positive appraisals in other areas. Ex. Apple viewed in high esteem -->even if they make an inferior item, their products will still be favored
Marijuana effects
can be a stimulant, depressant, or hallucinogen Acts on endocannibinoid neurotransmitter system. Report mild euphoria, sedation, and increased appetite
What is an enveloped virus
cold virus and HIV spherical membranes surrounding a protein capsid and nucleic acid
What are sanctions
consequences for not following norms
Who is Jean Piaget
considered father of developmental psychology and major contributor to cognitive theory. Developed 4 stages of cognitive development
Describe electric potential
depends on position How much more potential does this position have relative to other position J/C=Volts=KQ/d
What is the photoelectric effect
electrons are ejected from material when light of a sufficient frequency is used, but not until that threshold is met
Specific heat capacity (and equation and water)
energy absorbance for one individual substance only DOESN'T change with changes in quantity c=q/mΔt specific heat capacity of water= 1cal/g°C or 4.18 J/g°C
What is internal energy
energy of internal vibrations and random motions of atoms and molecules within a system. Created when non-conservative forces such as friction and drag act, by converting kinetic energy to internal (Virtually the same as heat energy)
What is work
energy transferred by a force W=Fd W=1/2mv² W=Fdcosθ Unit: Nm=Joule=kgm²/s²
What is the heat of vaporization
enthalpy change associated with transition between liquid and gas. This will be 0 at the critical point because there is no active change between phases
∆H(formation)
enthalpy of formation from elements in standard state a negative value=exothermic a positive value=endothermic
What is hematopoiesis?
formation and differentiation of blood cells in red bone marrow
Describe red blood cell specific metabolism
glucose in all states; always via anaerobic glycolysis
Overmatching
limited size of population to the point where it's no longer representative (depressed people kick ball, but only looking at depressed people who play soccer)
What is an alpha linked carbohydrate?
linked through an oxygen atom on OPPOSITE side of the plane from CH₂OH group
Characteristics of phospholipids
lipid molecule with non-polar tail region s and polar phosphate heads
What is atomic weight
mass of any one mole of any atom Same as molecular mass g/mol
What is the 1st quantum number
n: the principle number describes the shell and the approximate relative energy of electrons in that shell
Frequency of a wave
number of wavelengths that pass a fixed point each second
What is the foot-in-the-door phenomenon?
people are more likely to agree to larger or more difficult requests if they first agree to a smaller request. The behavior of the person making the request changes the attitude of the person being asked to do something
What is the relative refractory period
portion of time during which the membrane is hyperpolarized action potential can be generated, but requires a stronger than normal stimulus
What is actin
protein monomer that polymerizes to form microfilaments
What is libido
psychosexual energy that focuses on different erogenous zones at different stages
What is the category size effect
recall and verification rates increase if the category has few members, and decrease with many members "A poodle is a dog" vs "A poodle is a mammal"
Source-monitoring errors (and heuristic vs systematic judgements)
recall errors in which source of memory is inaccurately identified Heuristic: unconscious determination of source based on clues or short-cuts associated with the memory Systematic: conscious determination of source based on intentional logical evaluation of the details remembered
Describe the synthesis of Alkanes from Alkenes
reducing an alkene with H2 in presence of metal catalyst Syn addition=both of the bonds are formed on the same side Anti addition=new bonds formed on opposite sides
Neural pathway is controlled where? What term relates to loss of alertness
reticular formation of the brain stem stimulates prefrontal cortex to maintain alertness A COMA= loss of this function
Describe how drug addiction works
stimulation of dopamine-based reward pathway in limbic system of brain
What is a lichen?
symbiotic relationship between fungus and algae
Time in air equation
t=2V/g (round trip time, or total time spent in air)
What is adaptive value
the degree to which a behavior increases evolutionary fitness. Traits with high adaptive value are more likely to be represented in future generations, and because of natural selection these behaviors will eventually result in a change in the gene pool.
What is social capital
the expected collective or economic benefits derived from the preferential treatment and cooperation between individuals and groups Example would be being part of a sorority or fraternity and upon graduating being hired by an alumn
What is positive feedback
the product of a reaction acts as an agonist for the product
Describe what light rays do in the eye
they are bent primarily by the cornea and only are adjusted by the lens. Lasik surgery reshapes the cornea, not the lens
Describe suburbanization and urban decline
urban overcrowding leads to sprawling suburbs. As people migrate out of the urban centers what they leave behind becomes depressed, resulting in slums and ghettos
How to calculate center of mass
weighted average of mass distribution Cmass=(r₁m₁+r₂m₂+r₃m₃)/mtotal
Role of seminiferous tubules
where sperm is produced, then moves to the epididymis where sperm is nurtured, fully matures, and stored until ejaculation
What is flagella/found where?
whip-like projections from the cell body used for locomotion sperm is the only cell in the human body with flagella
Describe metabolism of a 14C lipid
will need 6 rounds of β-oxidation Yields 7 NADH, 7 FADH2, and 7 Acetyl-CoA
Describe ∆H(fusion) and ∆H(vaporization)
∆H(fusion)= amount of energy (J/mol) required to go from solid to liquid or energy removed to go from liquid to solid--> Melting and freezing ∆H(vaporization)= amount of energy (J/mol) required to go from liquid to gas, or energy removed to go from gas to liquid --> Evaporation and condensation
What is a heuristic
"rule of thumb". Can be helpful in problem-solving, but can also cause functional fixedness and lack of cognitive flexibility
What is somatosensation
"touch" includes touch, texture, pain, pressure, stretching, temperature, and vibration Somatosensory cortex is in the parietal lobe
What determines the strength of contraction of a muscle
# of motor units being used size of motor units frequency of action potentials (stimulation)
Function of ADH
(antidiuretic hormone) in kidneys acts on *collecting duct*, making it permeable to water. If not for ADH, the collecting duct is impermeable to water. NET EFFECT= water retention and increased blood pressure
Describe Kirchoff's 1st and 2nd rule
*Both of these are used as rule that electric systems must follow* 1: Total current into a node=total current out of a node 2: In any closed loop, sum of voltages is equal to zero
What are Irving Janis' eight symptoms of groupthink?
-Illusions of invulnerability -illusion of morality -rationalization -stereotyping -self-censorship -illusion of unanimity -pressure to conform -mindguards
Oligodendrocytes and Schwann cells
-Oligodendrocytes: CNS -Schwann Cells: PNS -Both cell types synthesize myelin to support neurons
Erickson: Trust vs Mistrust
0-1.5 years old Favorable outcome: Trust in world around us and hope for the future Negative: Distrust and fear
Describe thermoregulation by the skin
1. Blood vessels closer to the surface of the skin DILATE when heat needs released and CONSTRICT when heat needs retained; blushing is from dilation 2. Arrector Pili muscles cause erection of hair follicles (goose bumps) that traps an insulating layer of air next to the skin. Contraction of arrector pili also generates small amount of heat 3. Subcutaneous fat provides insulation 4. Sweating, followed by evaporation of water in sweat, carries away significant amount of heat due to high heat of vaporization of water and its specific heat capacity
Resistor, Capacitor, and battery in parallel
1/R=1/R₁+1/R₂+1/R₃ C=C₁+C₂+C₃ Battery: add capacitance, but not voltage
Focal point equation
1/f=1/di +1/do
Pulmonary artery
10
ascending aorta
18
Erickson: Intimacy vs. Isolation
18 to 40 Favorable: intimate relationships and love Negative: Loneliness
proximal convoluted tubule
2
Describe confidence interval
95% is standard
Simple definition of operant conditioning
A change in behavior based on past outcomes
Hormones located in the posterior pituitary (characteristics)
ADH and oxytocin Are peptides, water-soluble, regulated by hormones secreted from the hypothalamus
What are examples of childhood stressors? What do they lead to
Abuse, neglect, exposure to violence lead to increased risk of major psychological disorders Divorce/marital problems lead to increased life stress as an adult, more family conflict, lack of social support networks, increased prosperity for learned helplessness War/Terrorism leads to PTSD and depression as an adult
What are the 4 main denaturing agents and describe how to renature them
Acid, Heat, Urea, and Mercaptoethanol Often not possible to renature proteins unless there was a slow and mild denaturant used to break hydrogen and sulfide bonds, but not other covalent bonds To re-fold, need to slowly remove denaturant, but not possible to renature with extreme heat or pH
Acquisition vs Extinction in classical conditioning
Acquisition= learning or developing of a skill, habit, or quality Extinction= when a conditioned stimulus is presented alone, the conditioned response will eventually stop
Newton's 3rd Law
Action-Reaction; When one object exerts a force on a second object, the second object always exerts an equal and opposite reaction on the first
What is an allosteric enzyme
Activity of the enzyme is influenced by the reversible non-covalent binding of another molecule
Acute and chronic physiological responses to stressors
Acute: stimulation of SNS Chronic: ulcers, decreased immune response, increased risk of heart disease, high BP, etc
Four (DNA) nucleotide bases and describe their characteristics
Adenine pairs with thymine via 2 H bonds Guanine pairs with cytosine via 3 H bonds Adenine and guanine are *Purines*: hex and pent ring Thymine and Cytosine are *Pyrimadines*: just a hex ring (also Uracil)
Aldosterone: location, class, function
Adrenal cortex steroid/lipid-soluble increases Na+ reabsorption and K+ secretion at the distal convoluted tubule and the collecting duct; net increase in salts in the plasma, increasing osmotic potential and subsequently blood pressure
Describe the Bobo doll experiment
Albert Bandura exposed children to adults modeling aggressive and non-aggressive behavior. The aggressive adult models repeatedly punched, hit, kicked, and spoke violently to Bobo. Non-aggressive models played quietly with non-aggressive toys. Control group with no models Children were then allowed to play in a similar room after watching the models. Those exposed to the aggressive models mimicked the violent behavior toward Bobo, while those exposed to non-aggressive model did not. Boys were more aggressive than girls. Children were more likely to model the behavior of a same-sex model. Girls were more likely to model the aggressive language, and boys were more likely to model the physical violence.
Describe the stability of alkenes
Alkyl substitutions increase stability Tetra-substituted more stable than Tri-substituted >Di > Mono
What is the basic structure of bacteria?
All bacteria are prokaryotes Capsule, peptidoglycan cell wall, plasma membrane, no complex membrane-bound organelles, single circular DNA chromosome, tiny circular DNA molecules called plasmids
What is hematopoiesis?
All blood cells develop from stem cells (undifferentiated cells) in the bone marrow
Differences between enzymes and catalysts
All enzymes are catalysts, but not all catalysts are enzymes Both effect reaction rate and energy of activation. Have no effect on equilibrium, Keq, yield, or percent yield Enzymes are organic and catalysts can be inorganic. Enzymes are typically specific for a substrate or group of substrates whereas catalysts are typically more universal
L vs D sugars in human body
All sugars in the body are D. L sugars don't occur naturally in body
Role of bulbourethral glands
Also called Cowper's gland Don't release any fluid to ejaculate, but secrete the pre-ejaculate fluid that lubricates and neutralizes any acidic urine in the urethra prior to arrival of other semen components
Describe buoyant force
Always exactly equal to the weight amount of fluid displaced by the object F=pvg (v=volume of fluid displaced; p=density of fluid, not object)
Describe what an amide is. Naming, characteristics
Amine group attached to a carbonyl Name by replacing -oic acid with -amide (butamide) This is the most stable carbonyl because -NH2 is not a good leaving group Resonance (double bond characteristic) limits rotation
Amnesia, Anterograde and Retrograde
Amnesia is the inability to remember events for a period of time, often due to an injury or illness Anterograde: loss of ability to create new memories after the event that caused the amnesia. LTM from before event remains intact Retrograde amnesia: loss of memory-access to events that occurred or information that was learned before the event
Alkoxy
An alkyl group singularly bonded to oxygen
What is an apoenzyme
An enzyme alone. Doesn't contain any cofactors or substrates
What is telomerase
An enzyme that adds bases to the ends of telomeres. Are turned off in mature somatic cells because this adds a timeclock for apoptosis. Telomerase remains active in sperm and egg cells and are passed from one generation to the next.
What are proteases
An enzyme that breaks down proteins and peptides Assists proteasomes
Describe acid chlorides. Structure of formyl chloride, acetyl chloride, and benzoyl chloride
Any compound with a carbonyl attached to a chlorine substituent on carbonyl C. Also known as acyl chlorides. Named with -oyl chloride (propanoyl chloride) These are relevant because they are the most reactive of all carboxylic acid derivatives. This is caused by the withdrawing power of chlorine, and the fact the chloride is such a good leaving group Formyl chloride=CHClO Acetyl Chloride=CH3COCl Benzoyl Chloride=C7H5ClO
What are Jung's 4 archetype's (describe)
Are unique to Jung, nothing comparable for Freud -Persona: how one presents themselves to the world and is often represented by the symbol of a mask - Anima(Animus): The female in a male (animus=male in a female). Virgin Mary might represent Anima -Self: an archetype in which the entire mind (both conscious and unconscious) is unified. Circles, squares, trees, and holy figures all serve as representations of the self -Shadow: an archetype that embodies uncertainty and danger and it is often alluring in some way
Describe the MP and BP of alcohols
BP will increase with increase in MW and decrease with branching Increase MP with increasing polarity and hydrogen bonding. MP will vary with branching Alcohols will have much higher BPs and MPs compared to similar hydrocarbons due to hydrogen bonding
What is the drive reduction theory of motivation? Primary vs secondary
Behavior is motivated by desire to reduce or eliminate an undesirable or uncomfortable internal state Primary drives involve physiological needs for survival (food, water, sex) Secondary drives are motivating because of association with and or produce access to the basic needs of primary (money, social status, fame)
SN2 reaction of epoxides SN1 reaction of epoxides
Both give rise to alcohols SN2 on top, SN1 on bottom
CNS vs PNS
CNS: brain and spinal cord. Made of interneurons only PNS: al neurons outside of the CNS; includes both sensory and motor neurons
Cyanide
CN⁻
Carbonate
CO₃²⁻
Blood calcium levels via hormones
Calcium elevated above normal levels --> thyroid releases Calcitonin --> Osteoblasts stimulated to take up calcium Calcium levels drop -->Parathyroid releases PTH --> Osteoclasts stimulated to break down bone
Proline role in proteins folding
Can be thought of as disrupting secondary structure or contributing to tertiary structure. Neither alpha helices or beta sheets have them internally Can be thought of as outside of the alpha helices or beta sheets because they are either in the turns of beta sheets, at the beginning of alpha, or in kinks of alphas
Describe how to synthesize alcohols (reducing)
Can generally reverse oxidizing reactions of alcohols NaBH4 can reduce aldehydes and ketones (too weak for carboxylic acids and esters) LiAlH4 and H2/Pressure can reduce aldehydes, ketones, carboxylic acids, and esters
What is a phototroph
Capture energy from sun via photosynthesis
What kind of peak is seen at 3000cm-1 on IR
Carboxylic acid (O-H); broad and will overlap the alkanes
Describe esterification. Where is this done in biology
Carboxylic acid with an alcohol in heat and acid give an ester and water This is how triacylglycerols are formed. Glycerol undergoes esterification with 3 fatty acids
Describe cardiac specific metabolism; skeletal
Cardiac= fatty acids during well fed state; fatty acids and ketones if fasting Skeletal= glucose during well fed state; fatty acids and ketones if fasting. Creatine phosphate is also a very short-lived energy source for short-bursts of action. Glycogen is still main fuel source
Which region of the brain is responsible for automated motor learning?
Cerebellum
What is obedience
Change in behavior that is a function of command from some authority figure Focus is on the behavior, the underlying attitude may not be affected
Difference between a competitive, competitive, and uncompetitive inhibitors: Graphs and values
Competitive: Inhibition because competes with substrate for active site Non-comp: Can bind [E], [E+S], and [E+P] Uncomp: keep the conformation locked in the [E+S] complex
Describe Spearman's theory of intelligence
Concept of general intelligence or g factor General intelligence is the bedrock intellect from which all other forms of intelligence are developed
What is a conditioned response and an unconditioned response in classical conditioning
Conditioned response= automatic response established by training to an ordinarily neutral stimuli Unconditioned response= an unlearned response that occurs naturally in reaction to the unconditioned stimulus
Function of the corpus callosum
Connects the right and left hemispheres of the brain No corpus callosum would result in individuals having difficult transferring information between the two hemispheres and have difficulties with problem solving. Impaired social behavior, variety of sensory impairments, and problems in muscle tone and motor behavior
Constructive vs destructive interference
Constructive=regions where amplitudes of superimposed waves add to each other, amplitude increases Destructive=regions where amplitudes of superimposed waves subtract from each other and amplitude decreases
Describe the characteristics of unsaturated triglycerides
Contain at least one double bond. Cis are good. They introduce kinds into the chain. Liquid at RT (cis) Generate fewer calories when metabolized (cis) TRANS=bad. Are a result of food processing. Enzymes for metabolizing unsaturated fatty acids are just for cis, so trans will just accumulate in the blood
What is cultural transmission vs cultural diffusion
Cultural transmission= also known as cultural learning. It is the way a group of people within a society or culture learns and passes on new information. Cultural diffusion= spread of cultural beliefs and social activities from one group to the next.
Nodes of Ranvier
D
Purkinje fibers
D
Describe how proofreading repairs DNA
DNA polymerase proofreads, catches, and repairs most mismatched pairs on the spot
Describe the sliding filament mechanism for muscles
Default low-energy position of myosin heads is bent. Between contractions, ATP hydrolysis provides energy required to straighten these myosin heads into their straight positions They are always attracted to and bind readily with actin (regardless of straight or bent configuration) They are not bound because tropomyosin is covering myosin binding site on actin filament Tropomyosin is clamped down by troponin, and when Ca is released from the SR, it binds to Troponin, releasing the clamp and freeing the binding site The higher energy straight position binds to actin, and relaxes back to bent position: ultimately dragging actin filaments with them (This is the power stroke of contraction) After the power stroke, ATP binds to the myosin head again facilitating it's release from actin filaments; tropomyosin will rebind to binding site and the attached ATP is hydrolyzed providing necessary energy to put the head back in straight position
What are delusions? Delusions of grandeur? Delusions of persecution? Delusions of reference? Thought insertion? Thought broadcasting?
Delusions of grandeur= inflated sense of self-importance or power Delusions of persecution= a belief that others are plotting to hurt or control them Delusions of reference= seeing personal meaning in a variety of mundane events that occurs around them Thought insertion= believing others are placing thoughts in their minds Thought broadcasting= belief that others have access or can hear their thoughts
Describe alcohol
Depressant "Messy" drug with effects on all sorts of neurotransmitter systems. Agonizes GABA neurotransmitter
What is dextratory vs levoratory
Dextratory (+) rotation of plane polarized light clockwise Levoratory (-) rotation of plane polarized light counterclockwise
What are geometric isomers
Differ in their geometric orientations Cis vs trans (E/Z)
Diploid vs Haploid
Diploid= 2n chromosomes Haploid= n chromosomes
What is disorganized behavior? What is catatonia?
Disorganized behavior= engaging in bizarre, pointless behaviors Catatonia= remaining abnormally still for extended period of time
Describe the Citrate-Acetyl-CoA shuttle and why it's used
During periods of energy abundance, acetyl-CoA groups in the mitochondria are redirected from the citric acid cycle to fatty acid synthesis. However fatty acid synthesis occurs in the cytosol and acetyl-CoA cannot pass through the inner mitochondrial membrane Acetyl-CoA is combined with oxaloacetate to form citrate, which is able to pass through membrane
What is the difference between educational segregation and educational stratification?
Educational segregation= students tend to be segregated into groups or classes within a school, or even different schools, based on race, SES, or similar differences Educational stratification= students tend to be separated into different classes or schools that have stratified curriculum of unequal difficulty. Eg private schools have more difficult curriculum, but are mostly reserved for families of upper SES. In public schools, having remedial, gifted, special ed classes
Where does Acetyl-CoA come from?
Either from pyruvate in PDH complex or as primary product of β-oxidation of fatty acids
Energy during formation and breaking of bonds
Energy is released when a bond is formed and required when a bond is broken
What is heat energy
Energy that is dissipated as heat. Usually occurs from a collision or current-carrying wire (Virtually the same as internal energy)
What is self-serving bias?
Enhance self-esteem. Focus on strengths and praise we may receive and downplay our weaknesses and negative feedback
Portions of the skin
Epidermis: outermost layer is avascular and made of mostly dead of dying keratinized cells Dermis: contains blood vessels, hair follicles, sebaceous glands (oil), sudoriferous glands (sweat), and nerve endings. Dermis is a connective tissue
Hormones released by adrenal medulla (characteristics)
Epinephrine and Norepinephrine Are tyrosine derivates and water soluble
Essential vs Non-essential amino acids
Essential: your body canNOT synthesize these, and you must ingest them Non-essential: your body can synthesize on it's own
Difference between eukaryotic and prokaryotic flagella?
Euk: whipping motion with microtubules and is made of tubulin Pro: spinning/rotating motion. Simple helices made of flagellin
What are exons? Introns?
Exons exit the nucleus. They are the coding sequences in mature mRNA. Introns stay inside the nucleolus. They are the non-coding sequences that are spliced out.
Blood glucose homeostasis mechanism
Food/Eating: causes increase --> beta cells of pancreas release insulin --> liver stores glycogen and somatic tissues take up glucose Fasting/Starvation: causes decrease --> alpha cells of pancreas release glucagon --> liver stimulated to perform glycogenolysis
Hypothalamus (subdivision, embryological origin, and function)
Forebrain From the prosencephalon is in charge of hunger, thirst, emotion (secondary); major endocrine function via releasing hormones to the pituitary gland
Basal ganglia (subdivision, embryological origin, and function)
Forebrain from the prosencephalon controls voluntary motor control, procedural memory
Thalamus (subdivision, embryological origin, and function)
Forebrain from the prosencephalon is in charge of consciousness (sleep/wake), relay between subcortical areas and cerebrum
Limbic system (subdivision, embryological origin, and function)
Forebrain from the prosencephalon is in charge of emotion (primary), and memory
Describe acetoacetic ester synthesis
Formation of a ketone from a beta keto ester
Serotonin (found where, primary regulatory functions, and any correlates to disease or psych disorder)
Found in CNS Associated with homeostatic regulation of sleep and appetite. Also involved in regulation of mood. Lower serotonin levels are associated with depression
Describe the changes in frequency and wavelength as they pass through different mediums
Frequency is constant as they pass through different mediums, but wavelength will change in mediums with different densities
Describe the galactose metabolism feeder pathway for glycolysis
Galactose is turned into Glucose-1P and then phosphoglucomutase coverts it into Glucose-6P for 2nd step
Describe the order of the electromagnetic spectra and the relative values of each (what is their speed in a vacuum)
Gamma > X-ray > UV > Visible > IR > Micro > Radio (frequency and energy, wavelength is reversed) Longer wavelength=lower frequency, less energy All waves have the same velocity in a vacuum: v=λf (c=3x10⁸m/s)
Function of lymphatic system
Gather excess interstitial fluid and return it to the blood; remove from the interstitial spaces proteins and other molecules too big to be taken up by the capillaries; monitor the blood and lymph for infection.
Describe Isoelectric Focusing
Gel is created with a stable pH gradient. Proteins in regions of pH lower than pI will move toward toward cathode (higher pH than pI will move toward anode) The protein will move through the gel and stop where their pI=pH
Total energy given from glycolysis and krebs cycle
Glycolysis= 4 ATP from NADH, 2 ATP as byproducts Krebs= 24 ATP from NADH, 4 ATP from FADH2, and 2 GTP as byproducts TOTAL= 36 ATP
Basic definitions: Glycolysis, Gluconeogenesis, Glycogenolysis, Glycogenesis
Glycolysis= consume glucose from blood stream Gluconeogenesis= making glucose from non-carbohydrate carbon sources Glycogenolysis= breaking down glycogen (glucose released from cell) Glycogenolysis= making glycogen (storing glucose for future use)
Testosterone: location, class, function
Gonads (testes) steroid/lipid-soluble stimulates development of secondary sex characteristics and closing of epiphyseal plates
What is attenuation
Gradual loss of intensity as a wave passes through a medium
Describe Gram positive vs Gram negative
Gram Positive: -Stains purple -Very thick cell wall -Form endspores -Single cell membrane Gram Negative: -Stains pink -Relatively thin cell wall -Do NOT form endospores -Contain 2 cell membranes; one inside the cell wall and one outside the cell wall
Characteristics of basophils
Granulocyte least common WBC. Granules contain mostly histamine, which they release when activated These chemicals promote inflammation and are integral in allergic reactions Basophils --> ALLERGIES
Where are halogens on periodic table
Group 97 (F, Cl, Br, etc)
List strong bases
Group IA hydroxides (NaOH, KOH, etc), NH₂⁻, H⁻, Ca(OH)₂, Sr(OH)₂, Ba(OH)₂, Na₂O, CaO Will dissociate 100% in water
Describe alpha hydrogens
H on C adjacent to carbonyl C. Are acidic due to resonance stabilization of conjugate base. 2 carbonyls separated by a single carbon will have alpha hydrogen as even more acidic due to greater partial positive charge on carbonyl C
Allyl
H2C=CH-CH2-R
Habituation (describe) vs extinction Dishabituation (describe)
Habituation is decreased response to stimulus after the stimulus has been presented multiple times Habituation is reduced response rate for innate (unconscious behavior) Extinction is reduced rate to a conditioned behavior Dishabituation is increased response to stimulus after habituation has already ocurred. It usually occurs after a long period of stimulation, when habituation is becoming significant and a second stimulus is then introduced
Describe the cognitive theory of dreaming
Hall Dreams are a conceptualization of our experiences; they are visualizations of our thoughts and perceptions about 5 concepts: our self, others, the world around us, morals, and conflict
Describe decarboxylation
Have to start with 2 carboxylic acids in a group Base catalyzed Forms CO2 as a product and keto-enol tautomer
Emile Durkheim on division of labor
He said that division of labor is beneficial for society because it increases the reproductive capacity, the skill of workers, and it creates a sense of solidarity. Argues that a division of labor helps establish a social and moral order within a society
Describe the stimulations in response to high glucose levels
High glucose levels will stimulate beta cells in the pancreas to secrete insulin. Insulin then stimulates glycogenesis in the liver. Glycogenesis is the the synthesis of glycogen for storage in liver.
Define electronegativity and describe the trend
How strongly atoms attract bonding electrons Electronegativity increases up and to the right
Describe Beta sheets
Hydrogen bonding between all carbonyl oxygens in one row and amide hydrogens in the adjacent row All residues are involved in H-bonding R groups are perpendicular to the plane on both sides Assumes pleated conformation that allows each carboxyl and amide to participate in H-bonding Fibroin (molecule of silk) is an example
Hydrogen and alkenes: electron withdrawing/donating?
Hydrogen is considered neither electron donating or withdrawing Alkenes are weakly electron withdrawing
Nucleus
I
Imitation vs Role-taking
Imitation=especially in children, modeling of other influences identity formation Role-taking=adopting and acting out particular role ("Cops and Robbers" or "Put yourself in their shoes")
Immigration vs emigration Push vs pull factors
Immigration= movement into a nation or region Emigration= movement out of a nation or region Push factors= aspects of a society that encourage emigration. Examples could be low wages, low standard of living, lack of employment, religious persecution or war Pull factors= aspects of a society that attract immigrants. Examples would be higher wages, higher standard of living, employment opportunities, or political freedom
Describe voltage gated sodium channels
Integral proteins that change shape ("open") in response to a disturbance in the resting potential across the membrane. In open state they allow for more rapid flow of sodium back into the cell
What is the interference effect; what is proactive vs retroactive interference?
Interference: a new memory thats very similar to existing ones can cause interference, or increased difficulty recalling original memory. (difficulty memorizing a second phone number because of a previous one) Proactive: old memories interfere with the formation of new ones Retroactive: new memories interfere with recall of old ones
Golgi Apparatus function and characteristics
Is the cellular "post-office" for proteins: it organizes and distributes the proteins continue post-translational modifications, excretes vesicles bound for plasma membrane, ER, or cellular organelles
Difference between kinesins and dyneins
Kinesins: move along microtubules from (-) to (+) (center of the cell to periphery) Dyneins: move along microtubules from (+) to (-) (periphery of cell to center)
Hallucinogens types
LSD (lysergic acid diethylamide), peyote, mushrooms
Compare single/double/triple bond length, stability, reactivity, and stregth
Length: single>double>triple Stability: Triple>double>single (thermodynamically stable) Reactivity: Double> Triple> Single (alkenes have slightly less stable pi electrons than alkynes) Strength: Triple > Double > Single
Contents of blood
Leukocytes (WBCs), erythrocytes (RBCs), antibodies (immunoglobulins), clotting factors (fibrinogen), transport proteins (albumin), and platelets Blood is connective tissue
Describe the stimulations in response to low glucose levels
Low glucose levels will stimulate alpha cells in the pancreas to secrete glucagon. Glucagon stimulates glycogenolysis in the liver. Glycogenolysis breaks down glycogen stored in the liver to form free glucose for release into the blood
What is molarity vs molality
M (molarity)= moles solute/liter solution --> will change with temperature m(molality)= moles solute/kg solvent -->doesn't change with temp
Magnification equation
M=-di/do a negative magnification means that the image is inverted
What is mechanical energy
ME=KE+PE In the absence of non-conservative forces (friction, drag, air resistance, etc.), mechanical energy is always conserved
Melting point and Boiling point
MP=temp that substances change from solid to liquid (freezing point is the same temperature) BP=temp that substances change from liquid to gas. Liquids boil when vapor pressure=atmospheric pressure
What is macrosociology? Microsociology?
Macro=large group and social institutions Micro=small groups or individuals
Describe PCR and steps
Makes more copies of a DNA fragment 1. Denature DNA by heating, which will separate the two strands 2. Cool down, and primers come in to do what is called Primer Annealing 3. Then slightly reheat, and the primer extends, this is done by Taq polymerase 4. You will then have 2x as much as you started with 5. Heat back up to start again with step 1
What is false consciousness (social class)
Members of a social class are unaware of themselves as a social class. Produces distorted perceptions of the reality of class and its consequences
Lipid metabolism, production, and modification location
Metabolized for energy in the mitochondria Synthesized in the cytosol Modified at the smooth ER (Fatty acid synthesis in the cytosol stops at 16-C palmitic acid. Elongation and modification then occurs in the smooth ER)
Difference between metals and non-metals
Metals are larger atoms with loosely held electrons; like to lose electrons (+) Non-metals are smaller atoms with tightly held electrons; like to gain electrons (-)
What is Major Depressive Disorder? What is a major depressive episode? Seasonal Affect Disorder?
Mood disorder with at least one major depressive episode. A major depressive episode (MDE) is depressed mood or loss of interest in normally-enjoyable daily activities, that interferes with normal functioning, and lasts for at least two weeks. The MDE criteria are also an important part of diagnosing Bipolar disorder. Seasonal Affect Disorder is MDD that occurs only at a specific time of the year
Describe the movement of metabolites around the cell
Most metabolic substrates are able to move freely or be transported around the cell; However most enzymes are trapped in one location, often embedded in a membrane
Path of air in inhalation/exhalation
Mouth/nose --> pharynx --> larynx --> trachea --> bronchi --> bronchioles -->alveoli
Describe the doppler effect
Moving toward=increase in frequency, decrease in wavelength (blue shift) Moving away=decrease in frequency, increase in wavelength (red shift) ∆f/f(source)=v(relative)/v(speed of wave)
Describe the lens of a person that is near-sighted vs far-sighted
Myopia (near)=able to focus clearly on close objects, but not distant. The image is formed in front of the retina and the lens is likely too curved Hyperopia (far)=able to focus on distant, but not close. Image is formed behind the retina, lens is too flat
Hydrazine
N2H4
Ammonium
NH₄⁺
What is race
NOT genetic or directly measurable. It is inferred or determined subjectively based on a certain set of phenotypic traits, such as facial features and skin color
What are conformational isomers
NOT true isomers a molecule twists or rotates around it's bonds (butane twisting)
Nitrite
NO₂⁻
Nitrate
NO₃⁻
Describe what an anhydride is, naming, and their reaction properties
Named same as carboxylic acid, but replace -oic acid with "-oic anhydride" (butanoic anhydride) They are excellent electrophiles, because leaving group is a resonance stabilized carboxylate ion
Describe an ester, naming, and bonding characteristics
Named with -oate ending, with R portion of -OR in front (methyl butanoate picture) Act as H-bond recipients, but NOT donors. Slightly soluble in water with shorter chains but less than acids or alcohols
Where is nervous tissue found
Neurons of the central and nervous tissue. Also includes glial cells (Ependymal cells have both nervous and epithelial characteristics)
Norepinephrine function and characteristics
Neurotransmitter at effector neurons of sympathetic nervous system (post-ganglionic of sympathetic) tyrosine derivative (water-soluble) produced in the adrenal medulla. Similar to epinephrine (increase blood sugar and heart rate), but also has the effect of raising blood pressure Often linked to stress
Acetylcholine characteristics Receptor types and where?
Neurotransmitter in parasympathetic nervous system and pre-ganglionic in sympathetic Nicotinic receptors: in skeletal muscles. Are ion channels that open in response to acetylcholine binding (excitatory) Muscarinic receptors: in heart muscle. Are triggering signal pathways that inhibit firing of action potential (slows heart rate)
Describe what a neutron is vs a proton (for decay)
Neutron is a proton and electron Proton is a neutron and a positron
What kind of peak is seen at 2250cm-1 on IR
Nitriles (CtripleN); sharp/deep
Describe the reduction synthesis of Nitro groups, nitrile groups, imines, amides
Nitro: can be reduced with LiAlH4, NaBH3, or H2/catalyst Nitrile: Can be reduced to primary amines with all 3, but most commonly uses LiAlH4 Imines: can be reduced to primary amines with all 3, but most often uses NaBH3 or H2/Cat Amides: reduced to primary amines with LiAlH4 only
Define simple diffusion
No ATP is required. High concentration to low with to assistance
Define facilitated diffusion
No ATP is required. Movement from high concentration to low concentration. Is mediated by carriers or channels
Are our bodies at equilibrium?
No they are in a dynamic steady state. If we were in equilibrium, we would be dead, we must constantly work to maintain a steady state that is far away from equilibrium
What is an enantiomer
Non-identical, non-superimposable mirror images Two molecules that have opposite R/S configuration at every chiral carbon Rotates plane-polarized light to the same degree, but in opposite directions Have the same physical properties (bp, reactivity, etc.) Except for how they rotate light and the products that they form when reacted with another chiral compound
Properties of ethers (reactivity, polarity, solubility, BP)
Non-reactive, weakly polar Short R groups=slighly soluble in water Most non-polar species are soluble in ethers Lower BP EXCELLENT solvents because they seldom react with anything giving any byproducts and low BP makes it easier to separate
What is Raoult's Law?
Non-volatile: Vp=XVp° (X=mole fraction of pure solvent; Vp°=Vp of pure solvent) Volatile: Vp(total)=Vp(solvent)+Vp(solute) or Vp(total)=X(solvent)Vp°(solvent) + X(solute)Vp°(solute)
Describe nucleophiles in organic reactions
Nucleophiles attack carbons (or other central atoms) electron dense having full or partial negative charge
Describe P1 generation, F1, and F2
P1 is the parents F1 is the first offspring F2 is the offspring of F1
Equation for optical power. Describe it's relation to ciliary muscles
P=1/f (unit is diopter; 1/m) flexing of ciliary muscles will increase the lens curvature. As the curvature increases focal point decreases. A decreased focal point equates to an increase in optical power
What is electric power (equation)
P=IV Either DC or AC DC is directly from battery, AC is household wiring (polarity and direction of current periodically reverse)
What is power. Units?
P=∆E/t or P=W/t Units=Watts (J/s)
Describe paper chromatography or TLC. What are the calculations associated
Paper chromatography uses paper as the stationary phase. TLC is identical, but it uses manufactured glass or plastic sheets coated with silica, alumina, etc. Calculation: Rf=Distance traveled by component /distance traveled by solvent Rf=0.9 means highly non-polar; Rf=0.1 means polar
Describe what pepsin is and where it comes from
Pepsin is the enzyme in the stomach that breaks down proteins via hydrolysis. Pepsin will begin as pepsinogen, which is a zymogen
What is social identity
Person's sense of who they are based on groups that they belong to
Describe phosphorylation and dephosphorylation in regulation
Phosphorylation is catalyzed by protein kinases and works by transferring a phosphoryl group from ATP to another molecule. This will turn the molecule "on" or "off". Dephosphorylation also functions to turn a molecule "on" or "off", but dephosphorylation doesn't usually result in recreating ATP. This is done using phosphatases and releases a free Pi. Phosphorylation and dephosphorylation are NOT reverse reactions
Describe age-related cognitive changes (physically and memory)
Physically: Brain literally shrinks in size and neural plasticity Overall memory: declines Procedural memory: stable Working memory: significant decline Semantic memory: stable
Primary vs secondary immune response
Primary response= immune systems first exposure and reaction to a pathogen Secondary response= immune systems response to that same pathogen during subsequent exposures
Describe primary vs secondary stress appraisal
Primary: initial evaluation of potential threat. Judge as either: irrelevant, benign-positive (good), or stressful (bad) Secondary: if threat is determined to be stressful, individual next judges whether they have the resources to cope with the stres
Oxidation of alcohols (what are the products of primary, secondary, tertiary)
Primary: oxidized to aldehydes and then carboxylic acids Secondary: oxidized to ketones Tertiary: cannot be oxidized
Trypsin and Chymotrypsin function and mechanism
Protein hydrolysis cleave proteins at the carboxyl side of amino acids Trypsin cleaves at Arginine and Lysine Chymotrypsin cleaves at Phenylalanine, Tryptophan, and Tyrosine
What is a protein? Oligopeptide? Polypeptide?
Protein is amino acid polymers Oligopeptides=very small chain of amino acids Polypeptides=longer chain of amino acids
Pyranose vs furanose
Pyranose= 6-membered ring Furanose= 5-membered ring
What happens with the pyruvate after glycolysis? NADH?
Pyruvate: If O₂ available, pyruvate is oxidized all the way to CO₂ and many molecules of ATP are made NADH: If O₂ is present, NADH passes electrons to the ETC, and regenerates NAD+ for glycolysis again
What is the combined gas law?
P₁V₁/T₁=P₂V₂/T₂
Ketal
R2C(OR')(OR")
Acetal
RHC(OR')(OR")
Nitro
RNO2
What is relative vs absolute poverty
Relative= low income compared to other individuals Absolute=income too low to provide life necessities, persisting for a period long enough to cause harm or endanger life
What is the difference between religion and religiosity?
Religion= formal beliefs, values, or doctrines taught or associated with a specific church or group Religiosity= a more broad term encompassing any guiding belief or behavior by an individual regarding ultimate or transcendent issues (e.g. purpose of life, death, life after death, morality, ethics)
What is resonance structure and what exists
Resonance structures are snapshots of different arrangements of actual structure. The actual structure is a hybrid of all the resonances, with the most stable structure contributing the most to the actual structure The most common resonance will be the one that allows the most full octet and has the least formal charge More resonances in a species=more stable
Describe an electrolytic cell
Same as a galvanic cell, but an external voltage is applied, forcing the electrons to flow in opposite direction The species with the lower reduction potential will be reduced here, and the cell potential is always negative Cathode=negative; anode=positive (different than galvanic); but reduction still at cathode and oxidation at anode
Describe fractional distillation
Same as simple distillation, except a fractioning column is added The mixture is heated to slightly above boiling point of the more volatile liquid. The impurities in the mixture (those that are not in the more volatile) will condense on the column and fall back into the flask. Results in better separation and can be used for substances that have BPs less than 25 degrees C apart.
Describe vacuum distillation
Same as simple/fractional distillation, but the air inside of the apparatus is evacuated. This dramatically lowers the boiling point, and allows you to work at more manageable temperatures. Essentially drives down the atmospheric pressure to meet the vapor pressure
Where are alkaline earth metals on periodic table
Second column
Sensation vs perception
Sensation: physiological process involving sensory receptors and action potentials Perception: psychological process that makes sense of the signal, influenced by experience, bias, etc)
Describe skin temperature, skin conductivity, heart rate, and BP in response to emotion
Skin temp: decrease during fear, increase during anger Skin conductivity: indicator of general stimulation of SNS Heart rate: increase in anger or fear, decrease during happiness BP: increase during anger, fear, sadness, and happiness
What is an oligarchy?
Social system under the control of a small elite. People prefer to let other's make decisions for them, system is so complex that people can't possibly know enough to intelligently partake in the decision making, those in power tend to stay in power and are unwilling to give up any of that power
What is the difference between a sociopath and a psychopath
Sociopath= severe deficit of conscience Psychopath= complete lack of conscience
Somatic vs Autonomic nervous system
Somatic: voluntary, innervates skeletal muscles. Contain both sensory and motor subdivisions Autonomic: involuntary; innervates cardiac muscle, smooth muscle, and glands; contains both sensory and motor subdivisions Both are part of the PNS
What is a social construct
Something developed or created rather than directly observable or measurable. Constructs are thought of as more subjective than objective, more theoretical than empirical.
Where are post-translational modifications made
Start in the RER and continue in the golgi
What are the start codons? Stop codons?
Start: AUG; does code for Methionine Stop: UGA, UAA, UAG; doesn't code for anything
Describe the torque equation and the units involved
T=Fl (l=lever arm) T=Frsinθ rsinθ only used when the force being applied isn't perpendicular Units: N*m
Describe nucleophilic attack of carboxylic acids
TOP of picture
Describe step 4 of glycolysis and why it's significant
The aldolase will produce each of these, with step 5 transforming the dihydroxyacetone phosphate into glyceraldehyde 3-phosphate, giving double the products in the end
How to determine oxidation state/what it is
The apparent charge an atom takes on. The oxidation state must equal the net charge Determine by looking at periodic table and bonding (MgO = Mg 2+; O 2-) Fluorine=-1 Hydrogen=+1 Oxygen=-2 (Peroxide=-1)
What do Gestalt Principles do
They all explain some way in which our minds automatically: -group individual parts of a stimulus together to make it more organized/pleasing -organize individual parts of a stimulus into a familiar pattern -fill-in missing parts to create a more logical whole
How do hormones work?
They always act to return the system to homeostatic conditions. They never cause a drift away from normal.
Describe the difference between α-glucose and β-glucose
They are anomers Different stereochemistry at anomeric carbon
Describe the difference between D-glucose and L-glucose
They are enantiomers Same name still
Describe the difference between glucose and galactose
They are epimers Different molecules
Describe neural support cells
They are not neurons that conduct electrical potential, but rather provide support to neurons. Schwann cells (oligodendrocytes in CNS), cells lining cerebrospinal fluid cavities (ependymal cells) and structural support cells (astrocytes)
What is the true-false effect
True statements are verified quicker than false statements are negated
Describe aldol condensation
Two aldehydes will react in base to give an aldol (aldehyde attached to alcohol). They are then condense and give enal
What are post-translation modifications? Where do they occur?
Usually include addition of polysaccharides, lipids, or phosphates Occurs at ER and Golgi Apparatus
Occipital lobe is responsible for
Vision
What is Charle's Law?
V₁/T₁=V₂/T₂
Work equation and units/measurements
W=Fdcosθ or W=Fd Unit=Joules (N*m) Work is positive when work is done ON system Work is negative when work is done BY system (work is positive if force and displacement are in the same direction)
Automatic vs Rule-based processing
Ways to associate two events Automatic: unconscious, unintentional, and stimulus-driven; association is determined by the event (stimulus) experienced Rule-based processing: conscious and intentional. Driven by both the event (stimulus) experienced AND by language, cognition, or formal reasoning
What is the Venturi effect?
When there is a constriction in a tube, the velocity of the fluid will increase at that point while the pressure will be lower.
What is the function of the small intestine
Where the majority of all digestion and absorption occurs. Digestion primarily occurs in the duodenum, and absorption is primarily in the jejunum and ileum
Describe glycogen
a glucose polysaccharide branched, alpha-linked glucose polymer used for energy storage in animals
Describe starch
a glucose polysaccharide branched, alpha-linked glucose polymer used for energy storage in plants
What is the Rorschach Inkblot Test?
a projective technique in which respondents' inner thoughts and feelings are believed to be revealed by analysis of their responses to a set of unstructured inkblots
What is Generalized Anxiety Disorder (GAD)
a prolonged and exaggerated sense of worry that has few or no verifiable causes. May be accompanied by an exaggerated startle reflex, trouble sleeping, headaches, nausea, fatigue, excessive sweating, etc
Describe the combustion of alkanes
a radical exothermic chain reaction with oxygen HIGH energy of activation CH₄ + 2O₂ → CO₂ + 2H₂O + HEAT Stable molecules have low heat of combustion (cyclopropane>cyclobutane>cylooctane>cyclohexane)
What is meritocracy
a society in where advancement or opportunity is based on merit (ability or accomplishment). Term also refers to societies where government leaders are selected based on merit, as opposed to class (aristocracy) or pedigree (monarchy)
What is an aqueous solution
a solution where water is the solvent
What is evolutionary bottleneck
a sudden decrease in the number of individuals in a population
What is absolute pressure?
actual total pressure of atmosphere and gauge pressure
Percent yield
actual yield/theoretical yield
Describe the acid-base functionality of amino acids
all amino acids are WEAK ACIDS All have a minimum of 2 acidic protons (NH3+ and COOH); some have 3 Each amino acid therefore has 2 or 3 pKa values The amino acid will then act as a buffer when the pH is near the pKa of one of the acidic protons
Describe the characteristics of a steroid
all steroids are 4-membered ring structures (A,B,C,D)
Describe Mendel's Law of Segregation.
alleles segregate independently of one another when forming a gamete
What are networks
an established pattern of social relationships between individuals
What is culture shock
an experience of personal disorientation when confronted with an unfamiliar way of life. Most intense when traveling abroad.
What is a stressor (catastrophe vs life events vs daily hassles)
an external event, condition, or stimulus that leads to stress Catastrophe=animal attack, severe weather, war Life events=new job, marriage, divorce, death of loved one, increased responsibility Daily hassles=poor phone connection, waiting in traffic, long to-do list
What is a prion
an infectious protein results from misfolding
FSH: location, class, function
anterior pituitary peptide/water-soluble stimulates growth of follicle during menstrual cycle and production of sperm
hGH: location, class, function
anterior pituitary peptide/water-soluble stimulates growth throughout the body
Prolactin: location, class function
anterior pituitary peptide/water-soluble stimulates milk production in the breasts
TSH: location, class, function
anterior pituitary peptide/water-soluble stimulates release of T3/T4 from the thyroid
What is Eugenics
any belief, method, or practice designed to improve genetic makeup of human race. Usually by preventing birth, reproduction rate, or survival of individuals deemed to have less desirable genes
What is a polarimeter
apparatus that measures the rotation of plane-polarized light as it passes through sample
What is experimental research
basic science research highly controlled lab research not on humans. most reliable for causation
What is internal resistance
batteries all have an internal resistance due to internal components
Glycogenolysis (describe)
biochemical breakdown of glycogen to glucose (opposite of glycogenesis). Takes place in cells of muscle and liver cells
Where is connective tissue found
bones, cartilage, lymphatic tissue, fat, blood if a cell isn't one of the 3 other tissues, it is connective
How are pituitary hormones regulated
by hormones secreted from the hypothalamus hypothalamus hormones have similar naming pattern as pituitary, but have "releasing" in the name: Gonadotropin-releasing hormone
What is cAMP and where does it come from
cAMP is a common second messenger molecule. Loss of a phosphate transitions ATP --> ADP--> AMP -->cAMP The only difference between ATP and cAMP is the cyclization. Transition from AMP to cAMP is endergonic, whereas the other two transitions (ATP, ADP, AMP) are all exergonic cAMP is higher energy than ATP
Respiratory Acidosis
can't remove enough of the CO₂ increase in CO₂ → increase in Carbonic Acid (H₂CO₃ ↔ H⁺ + HCO₃⁻) → Decrease in blood pH Carbonic anhydrase converts CO₂ and H₂O to H₂CO₃ TYPICALLY: ↑CO₂→↑H⁺ and bicarbonate in RBCs → More O₂ released
What is an autotroph
capable of fixing CO2 and can use CO2 as carbon source for synthesizing molecules
Short-term memory
capacity for holding, but not manipulating, a small amount of information in the mind in an inactive, readily available state for a short period of time
Function of ascending loop of Henle
carries filtrate out of medulla and back into the cortex. It is impermeable to water, and actively transports ions out of the filtrate and into the medulla. At the top of the loop, the filtrate would be less concentrated
Describe what spontaneous hydrolysis does to DNA
causes DNA damage DNA reacts in solution without external stimuli or chemicals. Amine groups on DNA react with water to form a carbonyl; entire base replaced with a hydroxyl
What is endocytosis
cell takes up small particles by invagination of plasma membrane to form vesicle called endosome
What is the opponent process theory?
centered on homeostatic principles Addiction to drugs, the body "learns" to expect heroin to come onboard, and body mounts an opponent process the opposite way of heroin effects Stop taking heroin=body has dysphoria and withdrawal symptoms
Describe the E/Z convention
cis/trans Z= highest priority groups on on the same side E=highest priority on opposite sides
What is role conflict
clash between roles associated with 2 or more statuses
What does the frontal lobe control
conscious movement (motor cortex), executive functions, language (Broca's area), reasoning, judgment, problem solving, etc
What is the role of the PDH complex
converts pyruvate to Acetyl-CoA; the linkage between glycolysis and the citric acid cycle
Covalent vs ionic bonding
covalent bonds share electrons within the bond Ionic bonds have one atom taking from another due to electrostatic forces
What is observed rotation
degree to which a sample rotates plane-polarized light Not a constant, varies based on concentration, length of tube, etc
Function of cardiovascular system
deliver oxygen and nutrients to cells and tissues of the body pick up CO2 and waste products and deliver them to lungs and kidneys
Nucleus membrane characteristics
double bilayer; one of which is continuous with the ER
What is the charge of one electron
e-=1.6x10⁻¹⁹ C
What do the peaks in H-NMR represent?
each peak represents all of hydrogens in a molecule that share indistinguishable chemical environment. They are called equivalent
Biological Predispositions
every subject has biological instincts that predispose toward adaptive response rats associate pain with light or sound but not taste; and associate nausea with taste but not light or sound
What is functional fixedness and how can it effect problem solving
example of a mental set in which, when solving a problem, we can only visualize using an object in the ways we have seen it used previously Explained best by Dunker's candle problem
What is a self-fulfilling prophecy?
false, yet strongly held belief or prediction about an individual or group that is accepted as true. False belief will eventually elicit behavior that matches belief. Mary scores high on a test. Teacher tells her she's remedial. She then scores worse
What are the 4 major agents of socialization
family (generally considered most influential), mass media, peers, work place other agents include religion, school, government
Role of ovaries
female gonads. Develop and release ova on a regular 28 day cycle Function as endocrine glands that secrete estrogen and progesterone
Describe laminar fluid flow
fluid flows in concentric sheets, each with different velocities. Fastest flow is the exact center and slowest flow is at interface with walls
What is atmospheric pressure
fluid pressure due to Earth's atmosphere at that location
Define selective attention
focus on one aspect of our environment and ignore the other aspects can lead to inattentional blindness: a lack of attention to what is not being focused on
What is phonology
focus on the phonemes (sound units within a given language) and how they can be combined in meaningful ways
Describe the total internal reflection
for total internal reflection to occur, light must be passing from a higher index medium to a lower index medium (glass to air)
What is tension
force in a rope, string, cable. Can usually ignore by replacing with a force vector on object that the rope is attached
What is fluid pressure?
force per unit area at some point within a fluid P=pgh Average force of molecular collisions per unit area, or weight of column of fluid above the point of measurement
Spinal cord (embryological origin and function)
from the inferior neural tube controls reflexes, bundled tracts to and from peripheral nervous system
Compare Electric Field with Gravitational Field variables
g=E (strength of electric field) G=K (electric field constant) h=r or d (distance in or radius in electric field) m=q (charge) F=F gh=V (voltage or electric potential)
Function of the respiratory system
gas exchange Inhalation and exhalation are necessary functions to deliver air to alveoli where gas exchange can occur. Oxygen will diffuse down its concentration gradient into the blood and CO2 will diffuse down its concentration gradient out of blood and back into the lungs
Describe adipose tissue specific metabolism
glucose in well fed state; fatty acid if fasting
Name the common monosaccharides
glyceraldehyde, dihydroxyacetone, ribose, deoxyribose, glucose, fructose, galactose, mannose
Describe glycogen metabolism feeder pathway for glycolysis
glycogen=glucose polymer, mostly in the liver, also high in muscles glycogen phosphorylase will remove glucose residues from reducing ends of glycogen polymers and produce Glucose-1P. Phosphoglucomutase will then convert glucose-1P to glucose-6P with then feeds into the second step of glycolysis
What does the temporal lobe control
hearing/language (secondary to the frontal lobe, in the primary auditory cortex), memory (hippocampus)
What is prestige (social class)
honor or deference attached to a social class and distributed unequally as a dimension of social stratification Distributed according to 3 factors: possessions, quality, and performance
What is a phase of a wave
how close two waves are oriented to one another. They have to have the same frequency and wavelength to be in phase, but can have different amplitudes
Describe saponification
hydrolysis of an ester to alcohol and salt of carboxylic acid Salt of a carboxylic acid (RCOO- +Na) is called a Soap
What is saponification
hydrolysis of esters (e.g. triacylglycerides, phospholipids, etc) Once a fatty acid attachs to a glycerol, it becomes an ester
Gender differences in health
in developed countries, women have longer life-expectancy than males Men are more prone to heart disease, diabetes, asthma, and various other chronic illnesses. Are also more prone to injury, or as casualties of war
Function of aldosterone
in the kidneys acts on *distal convoluted tubule* causing an increase in Na uptake. Also causes a reabsorption of Na out of collecting duct via insertion of Na channels, K channels, and Na/K ATPases in cells that line the collection duct NET EFFECT= water retention and increased blood pressure
Describe the MP and BP trends for alkanes
increase BP with increasing chain length and/or molecular weight decrease BP with more branching Increase MP with increase chain length and/or molecular weight increase MP with more branching (straight chain alkanes have the highest MP)
What is respiratory acidosis
increase in H+ concentration in the blood
What is a field
invisible influence capable of exerting a force on a mass or charge
What is stem cell therapy
it was assumed for years that neurons never regrow; that once dead, a neuron could never be replaced. Recent research has shown that the brain of healthy individuals does occasionally form new neurons out of pluripotent stem cells in the CNS; cells similar to neurologically-bound fetal stem cells This has provided hope for treating diseases like Alzheimer's and Parkinson's and holds out the promise of some future ability to regrow or repair nervous tissue
What happens if you insert a H+ channel into the mitochondria membrane
it will decrease the production of ATP because of it presenting an alternate pathway for the H+ gradient
Describe gas chromatography
liquid is used as the stationary (paper) phase. Mixture is dissolved into a heated gas and then passed through the liquid. Will reach the exit port at different rates depending on boiling point and polarity (only consider polarity if the two liquids have almost identical BPs) There will be one peak for each unique compound in the mixture. The height of the peak in a gas chromatograph is relative to the abundance of that compound
Define contralateral
literally means opposite side In reference to the brain, it refers to the idea that sensory and motor functions on the left side of the body are processed on the right side of the brain and vice versa
Case control
look at the people with the disease (cases) and people w/o the disease (controls) and look backwards in time for risk factors Retrospective
Describe Asch's conformity study
looked at peer pressure (1952) Students were grouped (6-8) and all but one was told that their job was to put pressure on the remaining person to answer the wrong way Found that 1/3 of students would be willing to question their own beliefs/judgments in the face of disagreement with others
Describe alpha decay
loss of one He nucleus (2 protons and 2 neutrons)
What is deindividualization
loss of one's sense of themselves and personal responsibility when part of a large group Often is associated with Mob Mentality (violence and destruction) Also associated with charitable events (prosocial behavior)
Malignant vs benign
malignant= currently exhibiting uncontrolled growth and are likely to metastasize Benign= tumors that are slowly growing, have not invaded other tissues, but could become cancerous later on
What is ppm and mass percent
mass percent= mass solute/total mass of solution *100 ppm= mass solute/total mass solution x10⁶ (or multiply the mass percent by 10⁴
Where is physical digestion
mastication, churning in the stomach and breaking food into smaller pieces. This includes emulsification of fats by bile
What is an insulator
material with a very high resistivity. Cannot have an ideal insulator that allows zero current flow. Glass, wood, and teflon are good insulators
Count 1 to 10 with IUPAC prefixes
meth, eth, prop, but, pent, hex, hept, oct, non, dec
What is the half-equivalence point
mid-point of horizontal portion of graph pH=pKa; [HA]=[A⁻] Strong acids and strong bases don't have half-equivalence point
What is Weber's Law
minimum JND (just noticeable difference) for a stimulus is directly proportional to the magnitude of the original stimulus That is why a difference in temp from 25 to 27 is detected by 70 to 72 isn't "Requires an X% change"
Racial differences in health
minorities have poorer health, less access to healthcare, and are more prone to engage in unhealthy behaviors Race and class are different constructs, but are often considered together with regard to health disparities
What is the endosymbiotic theory and explain it's implications
mitochondria evolved from aerobic prokaryotes that were engulfed by a larger "host prokaryote" this results in mitochondria having it's own circular DNA like prokaryotes; the genes of the mitochondria are only passed down through the maternal line
What is tRNA
molecule that bridges gap between mature mRNA and assembled protein. Has an anti-codon on one end and other end is covalently bonded to amino acid associated with that anti-codon
What is the role of the musculoskeletal system
movement, support and stabilization, generation of heat, aid to circulation, and maintenance of homeostasis
What is the 3rd quantum number
m∨l: magnetic quantum number gives the orbital orientation and values of -l to l Describe area of the subshell that electron is most likely to be found in
What is the brush border
name of microvilli and collection of mucus and digestive enzymes intermingled within them in the small intestine
Naming system for ketones. What is the structure of acetone
named with -one ending. If must be named as a substituent , it is called an oxo- group (4-oxopentanal)
What is pinocytosis
non-specific endocytosis of extracellular fluid and very small particles; occurs in all cells
Where are proteins that are bound for the cytosol made
on free floating ribosomes in the cytosol
Microtubule function and characteristics? Found where?
one of 3 primary contributors to the cytoskeleton an alpha and beta tubulin will form a heterodimer that is assembled into long chains called protofilaments. 13 protofilaments then surround hollow core to make 1 microtubule Found in places that contain cilia (lungs, ependymal cells of brain, and fallopian tubes), flagella of sperm, and in all cells as part of cytoskeleton
Describe Freud's Ego
operates in the conscious, PRE-conscious and unconscious realms Responsible for helping the desires of the Id to be realized in a way acceptable in real-life scenarios. Also helps balance the perfectionist tendencies of the Superego NOT present at birth; develops from the Id
Pain killers (types and effects)
opiates and opioids Have pronounced analgesic (pain killing) properties, act on opioid system in the brain. Feelings of euphoria when smoking or IV usage Effect motility of smooth muscle, temperature regulation, HR, and RR
What is confirmation bias
overestimate of how "right" we are. Seek out and attend to information that agrees with our own perspective while ignoring counter information
What is confirmation bias
overestimating how "right" we are by seeking out information that agrees with our own perspective and ignoring information that might challenge previously held beliefs
Describe the levels of estrogen and progesterone through the various reproductive stages
ovulation requires a surge in hormone levels, whereas menstruation requires a chronic decline Persistent low levels leads to symptoms of menopause
What is a chemotroph
oxidize organic or inorganic molecules to harvest energy
Henderson-Hasselbalch equation
pH=pKa + log(base/acid)
Characteristics of mast cells
permanent resident cells within many tissues activated by allergens and other antigens to release histamine and other chemical mediators Usually associated with severe allergic reactions, including anaphylactic shock
What is compliance
person changes their behavior because they are asked to do so explicitly or implicitly an active attempt to alter one's behavior, but doesn't require changes in thought or attitude about the behavior
What is token economy
positive behavior is reinforced with tokens that can be exchanged later for prizes, treats, or other reinforcers.
Positive vs Negative memory recall
positive memories are usually remembered more easily and negative memories are forgotten more easily. People with depression often remember positive and negative equally. Older adults show stronger recall bias fo positive vs negative Positive memories usually encode more detail than negative
Describe the effects of chronic insomnia
positively correlated with decreased cognitive functioning, depression, and multiple chronic disease including heart disease, htn, obesity, and dm
How is a chemical transmission signal stopped
post-synaptic membrane will be continuously stimulated as long as neurotransmitter is present. Specialized enzymes in synaptic cleft must break down the neurotransmitter to interrupt its action Most common is acetylcholinesterase
Misinformation effect
presentation of inaccurate post-event information can cause an accurate memory to be altered or recalled inaccurately
What is the priming effect
presenting a related word first increases recall or verification rate If DOCTOR (primer) is presented before NURSE (target), it speeds the recognition of the word nurse
Characteristics of dendritic cells
professional antigen-presenting cells. They efficiently phagocytize pathogens and present antigens on their surface to stimulate other immune cells Are WBC's (leukocytes), but are not lymphocytes Can form from monocytes or independently in own cell line from blood cell precursor
Define apoptosis
programmed cell death featuring autolysis of cell contents by lysosomes. It is initiated in cells exposed to extreme heat, radiation, viral infection, DNA damage, etc. or to remove healthy unwanted cells (digits in embryological development)
Role of integumentary system
protects against abrasion, physical barrier to pathogens, vitamin D synthesis, insulation/cushioning (due to subcutaneous fat), prevention of water-loss, and temperature regulation Hair, skin, nails and oil/sweat glands located within the skin
What is a proteasome
protein complex that degrades unneeded or damaged proteins by proteolysis (chemical reaction that breaks peptide bonds)
Describe electron capture
proton is changed to a neutron via capture of an electron
Describe positron emission
proton is changed to neutron with expulsion of a positron
Describe the Bohr model
protons and neutrons are roughly the same size; electrons are 1/2000 the size There is a central nucleus with shells/orbitals surrounding it Contains energy levels that electrons can jump from one level to another in: When they relax back to lower leave, release a photon
What are polymorphisms
random variations in DNA sequence among individuals. Random, due to mutations. May or may not increase in future generations depending on whether or not that mutation provides an evolutionary fitness advantage
What is power
rate at which something does work P=Work/time J/s=Watt
What is specific gravity?
ratio describing how dense something is compared to water SG=D(substance)/D(water) If floating, fraction of object submerged=ratio of density of object to density of liquid
Define ipsilateral
refers to the same side for example the temporal portion of each hemiretina projects ipsilaterally because it receives information from the contralateral visual field
Function of distal convoluted tubule
regulates calcium, sodium, and hydrogen concentrations sodium reabsorption here is regulated by aldosterone hormone (ADH stimulates increased sodium reabsorption at DCT and collection duct) Also reabsorbs calcium in response to PTH
Describe mechanical waves
require a medium to propagate; cannot propagate in a vacuum. Transfer energy in direction of propagation, but don't transfer matter Can be transverse (strings on guitar) or longitudinal (sound waves)
What is a peer review?
research submitted and first reviewed and critiqued by colleagues prior to publication
Define regression
reverting to patterns of behavior that were used in earlier stages of life in order to deal with stress
Pulmonary circulation
right ventricle --> pulmonary arteries --> lungs --> pulmonary veins --> left atrium
What are biological and sociocultural motivators
root of many behaviors we exhibit regularly hunger, sex-drive, substance addiction
What are norms
rules and expectations by which members of society are expected to follow
What are folkways
rules for casual social interaction (everyone faces forward in an elevator)
What is syntax
rules that govern how words are ordered into meaningful sentences "Rules of grammar"
What are stereoisomers
same formula, same bond-to-bond connectivity, but different 3-D arrangement of their substituents (enantiomers and diastereomers)
Describe how extraction works
separates 2 compounds (or removes a desired product from a rxn mixture) by combining 2 immiscible liquids (polar and non-polar/organic). The separation is dependent on the target molecule have a different solubility in the 2 solvents. Generally the organic (non-polar) will be less dense than the aqueous (polar) so it will be on top
What is a nucleosome
set of 8 histone proteins in a cube shape with DNA coiled around it
Describe juxtacrine signaling
signaling that requires direct contact between two cells
What are standing waves
simultaneous constructive and destructive interference between 2 waves with identical frequencies, moving through same medium but in opposite directions Exhibits no net transport of energy and does not itself propagate
Nucleolus characteristic
site of rRNA transcription and ribosome assembly
Where is muscle tissue found
skeletal, cardiac, or smooth muscle
Describe Young's double slit experiment
slits are observed on a 3rd screen after shining through a single slit in 1st screen and double slit in 2nd screen x=λL/d Showed the dual nature of light
What is peer pressure
social influence exerted by a peer or peer group
Describe the 1st Law of Thermodynamics
some energy is lost to heat. Work and heat are the only ways energy can be transferred into or out of a system ∆E=W+Q
What is the adaptive role of emotion?
some evolved via natural selection. Disgust has scrunching nose and mouth, limiting intake of food and foul odors. Fear has widening of eyes, allowing more light in to identify threat.
What is mass hysteria
spontaneous, socially contagious, irrational behavior of a large group of people in response to an event (reading of war of the worlds over the radio)
What is cognitive dissonance theory
state of unpleasant psychological tension experienced when one holds 2 attitudes or beliefs that are in conflict with one another. Ease tension by changing attitude or belief to remove the conflict People are most likely to behave in a way that matches their attitudes i.e. There will be no cognitive dissonance when a person holds the attitudes as result of personal experience, is an expert in the subject, frequently expresses the attitude, expects a favorable outcome, has a risk of gaining/losing something based on outcome
Describe why water is a stronger acid than alcohol
strength of acidity depends on the stability of conjugate base and resonance stabilization
What is role strain
stresses among the roles associated with one particular status
What is the law of conservation of charge
sum of all charges remains constant in a closed system True for all collisions of particles. Relevant for tracking the decay of particles
What is social support
support provided to an individual by a social group or network Family, friends, coworkers who provide financial, emotional, advice, etc. These are also called support networks
What is mycorrhizae?
symbiosis between fungi and plant roots
Working memory
temporarily holds information available for processing; it is important for reasoning and guidance of decision-making behavior
What is McDonaldization?
tendency of a large organization to standardize operations, even when standardization would be non-sensical, in an attempt to achieve consistency and efficiency
Instinctive Drift in operant conditioning
tendency of a subject of operant conditioning to revert from a conditioned response to an instinctual response
Describe base excision repair of DNA
the base portion only is going to be excised via DNA glycosylase; other enzymes will then remove sugar-phosphate backbone. The DNA polymerase and ligase will then replace the nucleotides
What is Faraday's constant
the charge on one mole of electrons F= 9.6x10⁴ C/mol --> (1.6x10⁻¹⁹ ÷ 6.022 x 10²³ Different than a Farad, which is the amount of a capacitance necessary to hold 1 C of charge on a capacitor with a potential of 1V
What is the sentence completion test?
the client is asked to complete a sentence. clients can't figure out what the best or prefect answer is and it is difficult to fake an answer
Vasopressin regulates the insertion of aquaporins into the apical membranes of the epithelial cells of which renal structure?
the collecting duct
What is medicalization?
the process by which all human illness, disability, discomfort, or related problems, are assumed to have a medical or clinical cause and/or solution
What is assimilation
the process by which minorities gradually adopt patterns of the dominant culture. Second and third generation immigrants become less like the first generation family members
What is attribution in social thinking?
the tendency to infer that the behavior we see in others can be attributed to specific causes. Generally assumptions made ourselves without actual knowledge of the root cause
Calcitonin: location, class, function
thyroid peptide/water-soluble decreases blood calcium by inhibiting osteoclasts
Roles of hair cells in inner ear
transduce mechanical displacement caused by sound waves into neural impulses. These differ from other cilia because they do not have any motor capabilities
Describe the protein folding system
translated proteins assume secondary system almost instantaneously, then will fold into globular/tertiary states
What are fads
unconventional social patterns that are embraced briefly and enthusiastically by large number of people (tattoos and body piercings)
Describe the conservation of charge
universe always has zero net charge. Charge is created by separation
What is ketolysis
utilization of ketone bodies (from ketogenesis) by converting them to acetyl-CoA for energy. Occurs mainly in heart and brain, but NOT in liver
How to calculate wave speed (rules)
v=fλ Rules: 1. Wave speed is determined by the medium 2. Frequency never changes when moving form medium to medium 3. Wavelength does change when moving from medium to medium
What is verbal vs non-verbal communication
verbal=language of any kind (speaking, sign language, braille) non-verbal=eye-contact, gestures, body-language, etc (tone of voice is a common non-verbal communication)
What is a niche
very specific status or role an organism plays in its ecosystem
What is the lytic cycle
virus period during which viral genes are actively transcribed and new viruses are assembled. Infected cells usually burst to release large number of new viruses Examples would be active cold sores (herpes) or AIDS
What does the occipital lobe control
vision (primary visual cortex)
What is the Malthusian Theory of Population
was developed in response to a spike in population growth. Thomas Robert Malthus was an English economist who warned that unbridled population growth would lead to chaos. Said population would increase by a geometric progression (2,4,8,16,32) and population would eventually soar out of control. Food production would increase in a geometric (2,3,4,5,6) because of a limit of farmland People will reproduce beyond what that planet can sustain, leading to starvation and conflict over limited resources
End point of titration
when the indicator causes the color change no causal relationship between end point and equivalence point
What is a dihybrid cross
when two traits are being considered. Should always draw out two independent punnett squares, one for each trait. Then to calculate probability of having two traits, multiply the individual probabilities for each trait.
Role of ciliary muscles in eye
when you look at something near to your face, the ciliary muscles in your eye contract, causing the lens to become more curved and thick
right pulmonary artery
19
aortic arch
7
Medulla oblongata (subdivision, embryological origin, and function)
Hindbrain From the rhombencephalon Controls breathing, heart rate, and digestion
Pons (subdivision, embryological origin, and function)
Hindbrain From the rhombencephalon Controls sensory and motor tracts between the medulla and the cortex
Reticular formation (subdivision, embryological origin, and function)
Hindbrain from the rhombencephalon controls states of consciousness (sleep --> wake)
Cerebellum (subdivision, embryological origin, and function)
Hindbrain rhombencephalon Controls balance, refined motor movements
Define ionization energy and describe the trend
Amount of energy required to remove an electron It is hardest to remove from smaller shelled, noble gases than Cesium (Cs 2+)
Describe how a C13NMR is read. What is the range?
Analogous to IR, where functional groups will have a unique peak. Range of 0-220ppm, all peaks will be singlets. The area under the curve is not indicative of the relative number of carbons, given that there is no set ratio for the number of C13 present always
Describe a carboxylic acid (naming system, BP, and solubility)
Any compound with a carbonyl and hydroxyl substituent. Named -oic acid. (butanoic acid). Carboxylate anion (COO-) named -ate. Higher BP because of the dimer formation with the two H-bonds Short chain carboxylic acids are soluble in water and relatively non-polar solvents. Because of the dimer they form, they have no net dipole
Describe hormone regulation in terms of bones
Calcitonin= "tones your bones"; inhibits osteoclast activity, while osteoblasts continue. NET INCREASE PTH= stimulates osteoclasts. NET BREAKDOWN of bone matrix
What is Client Centered Therapy?
Carl Rogers One of the most widely-used psychotherapeutic approaches. It CCT, therapists should not direct the therapy or offer solutions. This is a MAJOR DEPARTURE from psychoanalysis, in which the therapist actively drives the interpretation of patients behaviors, dreams, etc. Therapist must always be empathetic, genuine, and show unconditional positive regard for the client, regardless of circumstance
Chemical properties of cis vs trans compounds
Cis=dipole moment and steric hindrance, higher heat of combustion, higher energy, less stable Trans= no dipole, no steric hindrance, lower bp
What is a phage
abbreviated "bacteriophage" virus that infects bacteria has a capsid head, a tail, and tail fibers
Characteristics of natural killer cells
lymphocyte recognize infected or cancerous cells and release cytotoxic granules that destroy the cell
What is melting, freezing, evaporation, condensation, sublimation, deposition
melting=solid to liquid freezing=liquid to solid evaporation=liquid to gas condensation=gas to liquid sublimation=solid to gas deposition=gas to solid
Describe information processing theory of dreaming
memories and information accumulated during the day are consolidated during sleep, dreaming is the cerebral cortex associating images or meaning with this consolidation process
Optic chiasm
part of the brain where the optic nerves partially cross
What is the word association test?
participants are provided a word and are asked to provide a word they associate with it
Bronsted-Lowry
acids donate protons, bases accept protons Always think of this definition when referring to acids/bases unless otherwise stated
Arrhenius Acid
acids produce H⁺ ions in solution; bases produce OH⁻
What is the learning theory of attitude change
attitudes are changed by learning. Classical conditioning, operant conditioning, and observational learning
What are dissociative disorders?
characterized by an apparent escape from one's identity as a means of avoiding stress (Dissociative identity disorder, Dissociative amnesia)
What is a test cross
crossing an organism with a dominant phenotype with one that has a recessive phenotype
Functional theory of deviance
deviance is not necessarily negative and is in fact necessary for social order. Deviance helps to clarify boundaries of social norms and can also play a positive role in initiating social change
Describe what chemiosmotic coupling is
direct coupling of the energy inherent in electrochemical gradient across inner mitochondrial membrane to phosphorylation of ADP to form ATP
Schachter-Singer theory of emotion
emotions are composed of 2 factors: a physiological component and a cognitive component. Physiological arousal is interpreted in context, which leads to emotional experience
James-Lange theory of emotion
emotions arise from physiological arousal. We only experience fear because of activation of sympathetic nervous system upon encountering a threat
What is the self-determination theory
emphasizes the motivational importance of 3 basic needs: 1. Autonomy: sense that one is in control of one's own lie choices 2. Competence: feeling capable at a task; ability to excel at something 3. Relatedness: sense of being accepted in social settings or relationships
Describe the rotation of plane-polarized light
enantiomers will rotate plane-polarized light R and S rotate light to the same degree, but in opposite directions Dextratory= (+) rotates light clockwise Levoratory= (-) rotates light counterclockwise
Function of Bowman's capsule
encloses glomerulus and catches filtrate as its formed and funnels it into the proximal tubule
What are the four types of tissue
epithelial, connective, muscle, nervous
Characteristics of lymph nodes
filled with lymphocytes These immune system cells monitor the blood for foreign antigens and fight infections
Function of blood
transport nutrients, gases, waste products and hormones to and from cells Regulate the extracellular environment; help maintain homeostasis; repair injuries; protect body from foreign entities (antigens)
Velocity of a wave
how fast a wave moves in space v=fλ
What is an aromatic compound How does Huckels rule apply to this
a conjugated unsaturated ring system that exhibits greater stability than expected from resonance or conjugation alone In order to be aromatic, a ring must have 4n + 2pi electrons
Cytoskeleton structure and function
a scaffolding-like network of microfilaments, microtubules, and intermediate filaments provides structure to the cell and creates a highway for intracellular transport
What is menopause
caused by persistent low levels of estrogen and progesterone characterized by hot flashes, vaginal dryness, atrophy of breast tissue
What is cartilage? Characteristics?
connective tissue composed mostly of collagen There are no perfusions or innervations Found in appendages such as nose and ears, at the end of long bones, between vertebrae, and at almost any joint or articulation
Epoxide
cyclic ether; 3 atom ring; highly reactive
Describe protein absorption
digestion begins in the stomach and is complete by the end of the small intestine. Proteins are broken down into small peptides and amino acids before absorption They will enter the bloodstream and travel to the liver
Describe longitudinal waves
disturbance is parallel to direction of travel (sound waves)
Characteristics of the uterus
elastic, muscular pouch that receives a fertilized egg via implantation and provides nourishment for developing fetus Muscle contraction of uterine wall stimulated by oxytocin facilitates childbirth
Authorhythmic process in heart
electric impulse originates in SA node, not from a nervous system signal Nerves do innervate heart, but only regulate rhythm up or down Vagus nerve slows HR, sympathetic nerves increase HR
Describe resistance
electrical equivalent of "drag" in fluids or friction in solids R=pL/A (p=resistivity, L=length, A=cross-sectional area) Resistivity will increase linearly with temperature in good conductors.
What is the social construction model of emotional expression
emotional response isn't biologically predetermined and all emotional response is based entirely on experience and context
Enthalpy
energy contained within chemical bonds measured with ∆H (Joules)
What are the accessory organs involved in digestion
Liver: manufactures bile Gall Bladder: concentrates and stores bile Pancreas: secretes bicarbonate into duodenum to neutralize acidic chyme from stomach. Also secretes 6 pancreatic digestive enzymes
Describe Poiseuille fluid flow
how real, viscous fluids actually flow. Exhibit laminar flow, have leading edge that is parabolic shape
Describe vaccines
inactive forms of virus are delivered to a person so that their immune system can develop antibodies Upon exposure, immune system will create memory B-cells. If later infected these memory B-cells will differentiate into plasma cells that rapidly produce and release antibodies for the virus.
What is social loafing
people will exert less effort towards a common group task because others are engaged in completing the task
What is situational personality theory?
personality (and behavior generally) is the result of external situational factors rather than internal traits or unconscious motivations.
An intrinsically disordered protein is an example of what
proteins with low hydrophobicity that do not fold into a stable structure, but can retain their function
Observational learning
generalized term describing any learning that results from observation of the behaviors of others
What is simultaneous move game? Sequential move game?
simultaneous=players act at the same time or in ways to make it impossible to know how other's act sequential=moves made in sequence with later players having some knowledge of previous players actions
What are the biological markers of schizophrenia
strongly associated with increased dopamine levels in the brain. Most anti-schizophrenic drugs are competitive antagonists that bind dopamine receptors. Having a family member with schizophrenia is a risk factor
What is a substrate
the molecule that is acted on by the substate and that is converted to product by the enzyme
Describe the Heisenberg uncertainty principle
the more we know about an electron's position, the less we know about the momentum
What are taboos
the most morally significant. Violating brings out a strong negative response (having consensual relations rather than forcing another to have sex)
What is adaptive radiation
the rapid formation of a variety of species from one ancestral species. Usually characterized by a strong environment-species connection
What is bioenergetics?
the thermodynamics of biological systems. Similar to how biochemistry is the chemistry of biological systems
left atrium
10
coronary sulcus
2
Magnetic force equation
F=Q(v*B)sinθ B=magnetic field=Tesla=N*s/C*m
Describe the Gabriel Synthesis
Alkyl halide and potassium phthalamide form a primary amine
Lever machine equation
F=mg(L₁/L₂) L₁=lever arm for mass L₂=lever arm for applied force
Ramp machine equation
F=mg(h/d) h=height of ramp, d=distance along ramps hypotenuse
What is normality
# of moles of equivalents/liter of solution 1M of H₂SO₄=2N 1M of H₃PO₄³=6N
What are macrophages role
engulf microbes and present antigens from those microbes on MHC proteins
What are the 3 germ layers and what do they give rise to
1. Ectoderm= epidermis, nails, tooth enamel, lens of eye, pituitary gland, central and peripheral and autonomic nervous system 2. Mesoderm= dermis, muscle, bone, connective tissues, kidneys, genitalia, and most internal organs except liver and pancreas 3. Endoderm= entire digestive tract, thyroid, parathyroid, urinary bladder, the lining of lungs, liver and pancreas
Explicit vs implicit memory
2 components of emotional memory Explicit: conscious memory of having experience the emotion (hippocampus) Implicit: unconscious encoding and storage of the actual feeling. May be retrieved and emotion "felt again" when encountering a similar experience, or during explicit recall (amygdala)
What is the hydrogen half cell reaction and how is it used
2H⁺ + 2e⁻ --> H₂ E°= 0V
ascending aorta
3
ascending limb of loop of Henle
3
renal column
3
right atrium
3
right ventricle
3
Erickson: Initiative vs Guilt
3 to 5 Favorable: sense of purpose and self-motivation Negative: guilt and inadequacy
What is Planck's constant?
6.626 x 10^-34 Js
What is a Zwitterion
A dipolar amino acid where the positively and negatively charged functional groups cancel each other out, resulting in a neutral ion All amino acids are zwitterions at physiological pH (7.4), except Asp, Glu, Lys, Arg, and His (Basic and Acidic Rs)
Area of a triangle equation
A=½bh
What are the 3 irreversible steps of glycolysis
All 3 are irreversible because of the large -∆G Step 1: phosphorylation of glucose by hexokinase Step 3: Phosphorylation of Fructose-6-Phosphate by phosphofructokinase Step 10: Transfer of phosphate from phosphoenolpyruvate to ADP by pyruvate kinase
Strength of electric field equation
E=F/q Electric field=electric force/charge g=F/m Point charge: E=kq/r²
Anti-bonding vs bonding orbitals
Anti-bonding orbitals have higher energy than bonding orbitals. Out of phase and repulsive Bonding orbitals are in-phase and attractive.
What are the 6 most common psychological disorders
Anxiety disorders (GAD, SAD, Phobias, Panic Disorder) ~18% Depressive Disorders (MDD, Bipolar, Dysthmyia) ~10% Substance Use Disorders ~7% PTSD ~3.5% Antisocial Personality Disorder ~1.5% Schizophrenia ~1%
What are neuroses?
Anxiety or mental disorders that result from fixations
Describe industrialization and urban growth
As society and the economy become more industrialized, people migrate to the urban centers
Difference between beneficence and non-maleficence
Beneficence=do go. Pt welfare is always primary consideration. End a study because of positive results and let others have treatment Non-maleficence=Do no harm. End a study because of negative results
What is Bipolar I vs Bipolar II
Bipolar I= individuals have full blown manic episodes Bipolar II= individual experiences less intense mania (hypomania)
What are coordinate covalent bonds
Both electrons shared in a bond are donated by one atom alone If an atom doesn't have a lone pair of electrons, it cannot be a coordinate covalent bond
What is closure, continuity, and common fate (Gestalt)
Closure: brain tends to perceive forms and figures in their complete appearance despite one or more parts being absent Continuity: when there is an intersection between two or more objects, people perceive as a single unit Common fate: when a stimulus is seen moving in the same direction, it is perceived as the same stimulus
What is torque (equation)?
Determined by the weaker of two forces T=Fd
Describe blood typing
Either A, B, AB, or O this describes the antigen that is present on blood membrane (O=neither) this is a co-dominant system because both A and B antigens can be present
Hormones located in anterior pituitary (characteristics)
FSH, LH, ACTH, hGH, TSH, Prolactin Are peptides, all water-soluble, regulated by hormones secreted from the hypothalamus
What are the 7 universal emotions
Fear, anger, happiness, surprise, joy, disgust, and sadness
What are the three types of joints
Fibrous= skull Cartilaginous= pubic symphysis, intervertebral discs Synovial= knee, elbow, etc
First way to think about work? Second way?
First always think of work as a change in energy Second think of work as Force x distance Always in J
Where are alkali metals found on periodic table
First column except H
Describe halogenation fo aldehydes/ketones
First they will tautomerize, and then Cl2, Br2, or I2 will halogenate in alpha position. Other halogen radical will take excess hydrogen from carbonyl
Bachmann's Bundle
G
Globule vs Molten
Globule=fully folded protein Molten Globule= partially folded protein Molten= fully unfolded/ DENATURED
Axon hillock
H
Over The HILL acronym and what each do
Increasing energy of activation Oxidoreductases= redox reactions Transferases= transfer functional groups (kinases, aminotransferases) Hydrolases= hydrolysis (breakdown with reaction of water) Isomerases= rearrangements (phosphoglucose isomerase, epimerases) Lyases= AB ↔ A + B (cleavage/synthesis with no water involved) Ligases= addition or synthesis of large molecules, usually ATP-dependent (DNA ligase)
What happens if you increase the percent saturation of Hb What happens if you decrease
Increasing= decreased [H+], [CO2], temperature and BPG Decreasing= increased [H+], [CO2], temperature, and BPG
Equation for kcat
Kcat = Vmax / [E]
What is the life course? What are transition and trajectory in relation?
Life course is a theoretical approach to studying human experience, aging or development. It considers an individual's entire lifetime as a whole and pays particular attention to life transitions and trajectories Transition= a significant, discrete change or event in one's life (first day of school, graduation, first marriage, first real job) Trajectory= a stable, long-term sequence of linked states, roles, or experiences (education, career, parenthood)
Describe sulfur linkages and the mechanism
Linkage between 2 cysteine residues
Hydroxide
OH⁻
What is the tissue organization hierarchy?
Organ systems > Organs > Tissues > Cells
Difference between osteoclasts, osteoblasts, and osteocytes
Osteoclasts= bone cells that break down and resorb bone matrix, releasing the component minerals (Ca2+ and P) back into the blood Osteoblasts= immature bone cells that secrete collagen, organic compounds, and mineral forming bone matrix around themselves. Once completely enclosed by matrix they differentiate into osteocytes Osteocytes= mature bone cells surrounded by a mineral matrix
Difference between the outer and inner mitochondrial membrane
Outer: lipid bilayer that is permeable to small molecules Inner: lipid bilayer that is NOT permeable to small molecules. Also has cristae (small folds) that increase the surface area for the ETC.
Describe oxidation vs reduction
Oxidation: Lose electrons, increase in O bonds, decrease in H bonds Reduction: Gain electrons, decrease in O bonds, increase in H bonds OIL RIG (Oxidation it loses electrons, Reduction it gains electrons)
Describe the oxidation of a secondary alcohol
Oxidized to become a ketone
What is the dissonance theory of attitude change
People change their attitudes because they feel cognitive dissonance, and change as a method to reduce discomfort
What is Boyle's Law?
P₁V₁=P₂V₂
What is paradoxical sleep
Phase used to describe ironic fact that during REM sleep, alertness, heart rate, breathing, and EEG patterns are nearly that of wakefulness, but muscles are paralyzed
How to calculate range
Range=Vt (V=horizontal velocity)
Role of red bone marrow vs yellow bone marrow
Red= where hematopoiesis occurs. Fills cavities of spongy bone Yellow= fills medullary cavity of long bones. Consists mostly of fat.
What is a period on the periodic table
Row going horizontal
Surface area of a sphere equation
SA=4πr²
SN1, SN2 vs E1, E2
SN1 competes with E1; SN2 competes with E2 SN vs E is determined by electrophile, steric hindrance, and strength of nucleophile/base Tertiary carbons can ONLY react via SN1 or E1
Sulfate
SO₄²⁻
What kind of peak is seen at 2800cm-1 on IR
Saturated alkanes (C-H); sharp/deep
What is a saturated solution? Unsaturated?
Saturated=contains maximum amount of dissolved solute it can hold. Ion product=Ksp Unsaturated=solution contains less than maximum amount of dissolved solute. Ksp> Ion product
What are sticky ends
Staggered fashion that restriction endonucleases leave (one side of helix is longer)
Describe surface tension
The intensity of intermolecular forces per unit length at the surface of a liquid
Volume of a sphere equation
V=4/3πr³
Describe Ohm's Law
V=IR Voltage=volts Current=Amps Resistance=ohms R remains the same (relatively, unless expressly changed). So an increase in voltage will result in an increase in current proportionally
What is vapor pressure
Vp is partial pressure of the gaseous form of a liquid that exists over that liquid when the liquid and gas phases are in equilibrium For every molecule that transfers to gas phase, one molecule transfers to liquid phase. Higher temperature=higher vapor pressure A liquid will boil when the vapor pressure of that liquid is equal to atmospheric pressure
Describe Binet's contribution to intelligence
Was the first to develop the intelligence scale (Binet-Simon intelligence scale) and concept of mental age vs chronological age. Designed to identify children who needed extra educational help and attention in school
What is the function of the large intestine
Water and vitamin absorption Absorbs vitamins from food as well as vitamins from beneficial symbiotic E. Coli in large intestine
Power units
Watts J/s (P=PE/time)
How to calculate distance (formula)
X=1/2at²
What is agoraphobia?
a persistent fear of any place or circumstance from which escape might be difficult. Individuals are usually fearful of being outside of their homes, traveling in a car, in a crowd, or in public places. May be accompanied by depressed mood, anxiousness, fearful behaviors, or panic attacks
What is residual volume
amount of air that is left in the lungs after a forced, maximal exhalation
What is a zymogen
an inactive enzyme precursor
What is a plasmid
bacterial DNA sequence used as a vector
What is a heterotroph
can't fix CO2 and must ingest organic molecules such as carbohydrates as their carbon source
Function of stomach
food storage and mixing. First stage of protein digestion. Slows passage of food through digestive tract, allowing time for complete digestion and absorption The proteins in the stomach will undergo hydrolysis catalyzed by PEPSIN
estrogen: location, class, function
gonads (ovaries) steroid/lipid-soluble stimulates female sex organs; causes LH surge in menstruation
Axial vs equatorial
in chair figure Axial=rise vertically Equatorial=extend horizontally
What are the biological markers of bipolar disorder?
increased monamine levels in the brain. Increased risk for persons with multiple sclerosis or who have a family member with bipolar disorder.
Describe histones
protein around which the DNA helix is wrapped during the first step of DNA condensation
What is disturbance of affect? Flat, inappropriate, blunted?
refers to emotional irregularities that can occur in individuals who suffer from schizophrenia Inappropriate affect= inappropriate emotions Blunted affect= significant reduction in emotional response Flat affect= complete lack of emotional response
What is the fluid mosaic model
refers to the dual-layer model of a phospholipid membrane two-opposite facing leaflets wit polar tails toward the center
What is temperature, relation to KE equation, and Kelvin equation
temperature is the average kinetic energy of molecules KE=3/2kB(T) --> kB is the Boltzmann constant Kelvin=°C+273.15
What is egalitarianism?
the doctrine that all people are equal and deserve equal rights and opportunities. In reality does not occur anywhere in the world, and never has in history
What does hydration mean
water molecules attached to ionic units in a solid
Risk factors for Alzheimer's disease?
women are at higher risk than men. A family history of Alzheimer's is a major risk factor
Describe the functionality in the enzyme pocket
works with the chemistry of the R groups A stabilizing feature of an enzyme may attract a substrate with opposite charge (a positively charged enzyme would stabilize a negatively charged substrate)
Sin of 45, 60, 90 Cos of 45, 60, 90
√2/2, √3/2, 1 √2/2, 1/2, 0
What are the 5 elements of culture
-Beliefs (religion, politics) -Language -Rituals (ceremonies, religious rites of passage, symbolic acts) -Symbols (flags, emblems) -Values (individualism, patriotism, communalism, Judeo-Christian values in the US)
3 kinds of heat exchange and what they are
1. Convection-fluid movement by hotter portions rising and cooler portions sinking 2. Radiation-electromagnetic waves emitted from a hot body to surrounding environment (light colors radiate and absorb less than dark) 3. Conduction-molecular collisions carry heat along a conduit; high energy molecules collide with neighbors, which collide with neighbors, etc.
What are Kohlberg's 3 stages of moral development
1. Pre-conventional: (pre-adolescence) obedience and self-interest 2. Conventional: (adolescence to adult) conformity, law and order 3. Post-conventional: (adulthood) social contract, universal human ethics
What are the 3 components of emotion?
1. Subjective experience: (AKA cognitive response) subjective interpretation of the mood or feeling experienced by the individual 2. Physiological response: physiological changes in HR, BP, breathing, and skin temp observed in the individual experiencing the emotion. 3. Behavioral response: facial expressions or body language that accompany emotional expression
renal pelvis
12
Erickson: Identity vs Confusion
12 to 18 Favorable: True sense of self and uniqueness Negative: Identity confusion
chordae tendineae
13
right atrium
13
interventricular septum
14
What is relative configuration
2 molecules will have the same relative configuration if their spatial arrangement is identical, but they have only one non-identical substituent
What are homologues
2 related but non-identical chromosomes (one from each parent)
inferior vena cava
21
tricuspid valve
6
Describe the later steps of glycolysis (6-10)
6. Glyceraldehyde 3-Phosphate → 1,3-Bisphosphoglyerate (via glyceraldehyde 3-phosphate isomerase; Pi and NAD+ converted to NADH) 7. 1,3-Bisphosphoglycerate → 3-Phosphoglycerate (via phosphoglycerate kinase; ADP to ATP) 8. 3-Phosphoglycerate → 2-Phosphoglycerate (via phosphoglycerate mutase) 9. 2-Phosphoglycerate → Phosphoenolpyruvate (via enolase; get H₂O) 10. Phosphoenolpyruvate → Pyruvate (via pyruvate kinase; turn ADP to ATP)
glomerulus
8
left atrium
8
Describe Gardner's theory of multiple intelligence and list
8 types of intelligence. Challenges the concept that all children learn in the same way, and says that IQ only examines, and wester culture only favors, linguistic and logical-mathematical 1. Visual-spatial: good with directions, maps, charts, videos, pictures 2. Body-kinesthetic: excellent hand-eye coordination and dexterity 3. Musical: Strong appreciation for music and often good at performance and composition 4. Interpersonal: Skilled at assessing emotion, motivation, desires, and intentions of those around them 5. Intrapersonal: self-reflection, daydream, exploring relationships with others, personal strengths 6. Naturalistic: highly aware of subtle changes to the environment 7. Linguistic: good at writing stories and memorizing information and reading 8. Logical-mathematical: think conceptually about numbers, relationships, and patterns
coronary sulcus
9
glomerular capsule
9
left pulmonary artery
9
left pulmonary vein openings
9
renal artery
9
What is ∆G°' for ATP hydrolysis
<<0 (~-30.5kJ/mol or -7.3kcal/mol)
Pressure volume work (describe)
=P∆V Work is energy transfer or change in volume at a constant pressure The area under the curve of a pressure vs volume graph=pv work REQUIRES CONSTANT PRESSURE
Dendrites
A
Sinoatrial node
A
Describe phosphorylation using ATP
A major human body regulatory mechanism. Many regulatory proteins, enzymes, and signaling molecules are turned "on" or "off" by phosphorylation via phosphoryl group transfer. Protein kinases are the enzymes that catalyze phosphorylation couple to ATP cleavage
Describe cell-mediated immunity
AKA T-cell immunity Involves T-lymphocytes (T-cells also made in the bone marrow but mature in the thymus) T-cells have receptor proteins embedded in their cell membrane, but unlike B-cells, they never produce free antibodies; instead they are "tested" in the thymus against host's own membrane proteins (self-antigens). All T-cells matching a self-protein are destroyed, leaving only cells that will recognize invaders. CELL-MEDIATED IMMUNITY= SELF-ATTACK of DISEASED CELLS
Epinephrine (found where, primary regulatory functions, and any correlates to disease or psych disorder)
AKA adrenaline Found primarily in the PNS associated with stress response elicited by activation of the sympathetic nervous system
Describe hydrolysis of ATP
ATP + H₂O → ADP + Pi + energy Almost always coupled to another reaction or process, such that the resulting energy can be used to drive that process (e.g. cocking the myosin head)
Where is ATP required/produced in glycolysis? NAD+/NADH?
ATP is required in steps 1 and 3 ATP is produced in steps 7 and 10 NAD+ is required in step 6 and NADH is produced in the same step
What is Active Transport
ATP is required to move across cell Always required to move something against it's concentration gradient or against an electrical potential
Describe how phosphoryl group transfers work in the consumption of ATP
ATP → ADP + energy Similar to ATP hydrolysis, except instead of a free phosphate being released (Pi), it is transferred onto another molecule Example: Glucose + ATP → Glucose-6-Phosphate + ADP (during glycolysis)
Accuracy vs precision
Accuracy= how close it is to the standard or known value Precision= how close two measurements are to one another
Describe the process of signal transmission starting with presynaptic membrane
Action potential arrives at presynaptic membrane --> triggers voltage-gated calcium channels to open --> Calcium ions flow into the cell --> Calcium initiates cascade of exocytosis of vesicles filled with neurotransmitters to fuse with presynaptic membrane and dump contents into synaptic cleft --> neurotransmitter molecules the diffuse across gap --> bind to receptors on postsynaptic membrane --> receptors usually associated with sodium channels --> if enough flows into the cell the threshold is reached
Purines vs Pyrimadines
Adenine and Guanine and purines (2 cyclo) Thymine (Uracil) and Cytosine are pyrimidines (1 cyclo)
Describe alcohol protection with TMS
Alcohol is treated with TMS(Cl) Reaction occurs Then treated with acid to remove the TMS and reattach the hydrogen to the oxygen
Describe alcohol protection with MOM
Alcohol treated with a base to remove the hydrogen Then treated with MOM which attaches to the negative oxygen Reaction occurs Then treated with acid to remove the MOM and reattach the hydrogen on the oxygen
Naming system for aldehydes. What is the structure of formaldehyde, benzaldehyde, and acetaldehyde
Aldehydes are named with -al ending (methane --> methanal)
Carbonyl
Aldehydes or ketones (not carboxylic acids)
Aldose vs Ketose
Aldose= aldehyde sugar Ketose=ketone sugar
What are the common always soluble? Always insoluble?
Always soluble: nitrate, ammonium, and group IA (alkali) metals Always insoluble: carbonate, phosphate, silver (Ag), Mercury (Hg), and Lead (Pb) Unless these are paired with something on the soluble list
Describe the relationship between attitude and behavior
Attitude influences behavior: absent of strong external influences, attitude generally guides behavior. The more strongly held the attitude, the more directly and quickly it will determine behavior Behavior influences attitude: our behavior can change our attitudes significantly. People tend to have a positive attitude toward behaviors they exhibit themselves, or towards things in which they personally participate
Why is hemophilia more common in males?
Because it is an X-linked recessive disorder. All X-linked recessive disorders are easier for males to get than females because they only need a single "bad X". There is no such thing as a male-carrier for an X-linked disease.
Basicity vs nucleophilicty
Basicity=function of thermodynamics; how much the molecule "wants" to react (not how quickly) Nucleophilicty=function of kinetics; how easily/readily a molecule will react (nothing about stability of new bond). Best nucleophile is one that reacts fastest with electrophile
What is repolarization
Because there are more K+ inside the cell (due to Na+/K+ pump), opening of the potassium channels causes K+ to flow out of cell This causes a sudden decrease from +40mV to -70mV
Describe sulfide bonds
Between two Cysteine residues Two oxidized cysteine residues (R-S-S-R) bond. Strongest protein folding interaction Between Keratin α-helices, more disulfide bonds =curlier hair
What is the biological personality theory vs the behavioral personality theory?
Biological personality theory=personality is predominantly the result of the expression of genes. Personality traits are the result of heritable biological characteristics. Behavioral= personality is the sum of those behaviors that have been reinforced over time.
What is the biomedical vs the biopsychosocial approach to psychological disorders
Biomedical approach= psych disorders caused by biological or chemical dysfunction (e.g. genetic predisposition, abnormally low hormone or neurotransmitter levels); treatments are primarily biochemical (surgery, drugs). Considered more narrow by psychologists, focused more on relieving symptoms Biopsychosocial approach= psych disorders caused by a combination of biochemical (genetic defect, low hormone level), psychological (personality, unhealthy behaviors), and sociological factors (culture, peer pressure). Treatments should include interventions in all three of these areas to be most effective
What is dependent personality disorder? What cluster is it a part of?
Characterized by a chronic, pervasive pattern of dependent, submissive, and needy behavior. Individuals may seek excessive approval, advice, or encouragement. May include sensitivity to criticism or rejection, low self-esteem, low self-confidence, an inability to make decision without others, feelings of helplessness, and extreme devastation when close relationships end-with the need to immediately begin a new relationship Cluster C
What is narcissistic personality disorder? What cluster is it a part of?
Characterized by an excessive sense of self-importance, an extreme preoccupation with oneself, and a lack of empathy for others. May be accompanied by a constant need for attention, affirmation, or praise, a belief that one is "special" and should only associate with others of the same caliber, fantasies about success and power, a sense of entitlement, or expectations of special treatment Cluster B
What is illness anxiety disorder (IAD)?
Characterized by heightened bodily sensations and intense anxiousness about the possibility of an undiagnosed illness. Individuals may devote excessive time and energy to health concerns, often obsessively researching them
Compact vs spongy bone
Compact= dense bone surrounding outside of all bones and constitutes the shafts of long bones. Organized in orderly units called osteons Spongy= interiors of flat and irregular bones, as well as bulbous ends of long bones. Contain many open spaces formed by interwoven trabeculae. Fill with red bone marrow
What is dissociative identity disorder? Dissociate amnesia? (DSM)
Disruption of identity with 2 or more distinct personalities Recurrent periods of amnesia for both everyday events and important personal experiences Disturbances fall outside of cultural/religious practices and imaginary play of children Disturbances have caused significant impairment of occupational or social functioning Disturbance not better explained by drugs or other medical condition
Distress vs Eustress
Distress= negative/unpleasant aspects of life (poor performance in school, losing job, divorce) Eustress= positive/pleasant aspects of life (graduating, getting married, new job)
What is a holoenzyme
a conjugated protein (protein that is associated with it's cofactors)
Describe the enzyme-substrate complex
E + S ↔ ES →EP ↔ E + P Occurs at the active site
Electric field, and equation
E=KQ/d² K is constant, Q is the charge and d is the distance from that charge
What is an empirical formula vs molecular formula
Empirical= lowest possible number of moles of each element that is allowed for the reaction (CH₂O) Molecular= actual number of moles found in the compound (C₆H₁₂O₆)
What are the 6 types of cellular communication
Endocrine, paracrine, autocrine, intracrine, juxtacrine, nervous system
What is cognitive bias and how can it effect problem solving
Error in thinking that leads to inaccuracy, illogical thought, lack of objectivity, failure to consider all available options or consequences, or prejudice toward one approach or outcome
Spring equation and how to use? Restorative vs Compressive Work to compress a spring
F=-kx (F=force on a spring; x=distance compressed) Restorative: F=-kx Compressive: F=kx W=1/2kx²
Pulley machine equation
F=mg/# of vertical ropes directly lifting mass
How are fats, carbs, and proteins absorbed in the small intestine
Fats are absorbed into the lymph system via Lacteals. Carbs and proteins are absorbed into the blood
Describe the Carnitine shuttle and why it's used
Fatty acids cannot pass through the inner mitochondrial membrane, where they need to be to go through β-oxidation Carnitine acyltransferase attaches fatty acyl group from acyl-CoA to hydroxyl of Carnitine
What is availability heuristic
Favoring the most easily recalled or imagined solution as a shortcut to making a decision or judgment
Dopamine (found where, primary regulatory functions, and any correlates to disease or psych disorder)
Found in CNS Associated with sensorimotor integration and in reward processing Parkinson's disease, Huntington's chorea, Tourette's syndrome, and schizophrenia are all associated with abnormal dopamine
Describe the psychoanalytical theory of dreaming
Freud Dreams are expressions of unconscious desires, thoughts, and motivations. Dreams can serve as a virtual form of wish fulfillment
Describe Freud's defense mechanisms
Freud theorized that as the Ego attempts to resolve anxiety between the Id (instinctual) and the Superego (idealistic), it resorts to unconscious falsifications or distortions called defense mechanisms.
What was George Herbert Meads I vs Me
George Herbert Mead was a symbolic interactionist that said that "I": is the active, spontaneous, autonomous self "Me": is socialized, sense of self is derived from others
What is Personal Construct Theory?
George Kelly Personality is composed of the various mental constructs through which each person views reality
Hormones released by pancreas (characteristics)
Glucagon and insulin Are peptides and water-soluble *Pancreas also releases digestive enzymes, but this is an exocrine function
Acid dissociation equation
HA + H₂O ⇌ H₃O⁺ + A⁻ Ka=[H⁺][A⁻]/[HA] -logKa=pKa 10⁻⁶ 6
Bicarbonate
HCO₃⁻
What is the difference between health disparity and healthcare disparity
Health disparity= higher burden of illness, injury, disability, or mortality experience by one population group relative to another Healthcare disparity= differences between groups in terms of health care coverage, access to care, and quality of care
What happens to the vapor pressure when a volatile liquid is added? Non-volatile liquid?
If a non-volatile liquid is added, then it will lower the Vp because it has a lower vapor pressure Adding a volatile liquid will also lower the Vp because it will now clog up all of the "exit ports" that the liquid has
What is the outcome of adult stressors
Life stress leads to depression, anxiety, increased substance abuse Traumatic events lead to PTSD and acute stress disorder (ASD)
What is positive cooperativity?
Ligand affinity increases with the binding of each subsequent ligand (hemoglobin) Binding affinity of first O2 molecule is low, but each subsequent O2 has an increased affinity
What is secondary protein structure
Local 3-D configuration of the peptide chain Alpha Helices and Beta Sheets
Describe the Glycerol-3-Phosphate shuttle and why it's used
NADH cannot pass through inner mitochondrial membrane into matrix, so NADH donates 2 electrons to DHAP so that it becomes G3P, which allows it to cross inner mitochondrial membrane
Describe the neutral stimulus, conditioned stimulus, and unconditioned stimulus in classical conditioning
Neutral stimulus= stimulus which initially produces no specific response. Will eventually become the conditioned stimulus Conditioned stimulus= previously neutral stimulus that has become the trigger to a conditioned response Unconditioned stimulus= one that unconditionally, naturally and automatically triggers a response
Null hypothesis vs Alternative hypothesis
Null-Lack of relationship or group difference When testing for correlation or causation, the Null is that there is NO relationship Alternative-opposite of Null. There is the presence of a relationship or group difference
Intensity of a wave
Power per unit area I=P/A (W/m²) I≈Amplitude²frequency² A=4πr⁴ (starting at a source and moving outwards) Only for sound, not light
What is a neuron and what are the 4 characteristics to know about it
Specialized cell that can carry electrochemical signal 1. Frozen in G0 phase (doesn't divide) 2. Depend entirely on glucose for energy 3. Don't require insulin fo glucose uptake 4. Have low glycogen and oxygen storage capacity, thus require high perfusion (blood flow)
What is neural plasticity (changes with age)
The brains ability to change structure and function to accommodate new memories, make new connections, create new motor skills etc. As we age, we have a loss of neurons. The frontal lobe and corpus callosum lose neurons at the fastest rate. The cerebellum eventually loses ~25% of it's neurons
Tell the story of transcription
__RNA Polymerase__ binds to the __promoter__ region. Helicase unwinds DNA, which forms transcription bubble. RNA polymerase reads in 3' to 5' direction, creating __Pre-mRNA__ transcript that matches the coding strand, but with U subbed for T. Termination factor release mRNA transcript. Post-translational modifications will splice out non-coding __introns__, leaving just the __exons__. A __poly-A tail__ is added to the 3' end, along with a 5' cap. This is then the mature mRNA that will be translated at a ribosome
What would chemiosmotic uncoupling do
a drug may uncouple at the ETC or electrochemical gradient. This means that the gradient is no longer directly driving ATP production and ATP synthase. This could be because the drug inserted proton channels into inner mitochondrial membrane that would continue pumping protons across matrix, but they have an alternative route back so it is no longer "coupled"
Describe cellulose
a glucose polysaccharide a beta-linked glucose polymer used for energy storage in plants. Is ingestible by animals without help from symbiotic bacteria
What is a motor unit? How are delicate vs gross movements performed?
a group of muscle cells innervated by a single motor neuron Delicate movements are done by small motor units; Gross movements are done by larger motor units
Describe the difference between a loose organization social movement and a social movement organization (SMOs)
a loose organization usually has little organization. There is rarely centralized, recognized organization that officially represents or speaks for the movement as a whole. "Leaders" are often unofficial or self-appointed Social Movement Organizations are formal organizations that constitute a sub-component of the movement. For example, environmentalism is a movement in the US that includes many SMOs
What is myosin
a motor protein; not a microfilament
What is self-image
a persistent mental picture of one's appearance and personality. Includes observable traits (height, weight, hair color, gender) and self-knowledge. Is derived from experience or internalization of the judgements of others ("People think I'm fat/nice/handsome") "My mental picture of my own personal characteristics/my appearance"
What are parasomnias? Give 2 examples
abnormal movements, behavior, perceptions, or emotions during sleep -Sleep walking (somnambulism) -Night terrors (pavor nocturnus)=severe anxiety, dread, or terror during first few hours of stages 3-4 (non-REM) sleep. Most common in children
CNS injury effect on plasticity
after a traumatic brain injury, brain has shown to have the ability to reassign some functions from the injured portion of the brain to other brain regions
What is ATP synthase
an embedded protein in inner mitochondrial membrane. Allows protons to flow down the gradient (back into the mitochondrial matrix) ADP is lodged in the ATP synthase protein, and the axel will spin and jam phosphate groups into ADP creating ATP and are then released back into the matrix
Describe Strecker synthesis
an α-aminonitrile is treated to form an amino acid
Characteristics of membrane receptors
any protein that specifically binds a signaling molecule that initiates cellular response
What is racialization
ascribing a racial or ethnic identity to a group that does not self-identify as that race or ethnicity
Quaternary protein structure and describe hemoglobin
association of multiple folded proteins into a multi-subunit complex hemoglobin is common, with 4 subunits (2 alpha and 2 beta). Each has heme capable of binding one O2 molecule (4 total)
Reaction quotient
at any time not at Keq If Q > Keq →reaction goes left If Q < Keq →reaction goes right
Describe radioactive decay
atoms change their chemical composition over time. The nucleus either gains or loses electrons, protons, or neutrons
Characteristics of the ovum? Define oocyte
begins meiosis and is arrested at prophase I at birth; not until puberty and menstruation is meiosis I completed Meiosis II is completed after sperm fertilizes the ovum Oocyte= an immature egg
Karsakoff's Syndrome (describe)
brain syndrome resulting from severe Vitamin B (thiamine) deficiency, most often from chronic alcohol abuse alcohol inhibits conversion of thiamine to it's active form; increased vomiting->inflammed GI -> poor eating -> deficiency
Psychophysics
branch of psychology interested in using precise, quantitative measurement of physical stimuli to understand the relationship between external stimuli and the sensations and perceptions they elicit
What is hydrolysis
breakdown of all nutrient molecules into their monomers
What are mirror neurons and where are they located
class of neurons that are active when we watch someone else perform a behavior, and fire again when we do that behavior located in the primary cortex and somatosensory cortex They also fire when we feel an emotion and when we observe someone else experiencing that emotion
What is the inflammatory response?
done by macrophages, mast cells, and dendritic cells. All are residents of nearly all tissues. When damage is caused, these cells are activated to release chemicals such as histamines, leukotrienes, and prostaglandins Chemicals increase blood blood to site, gives heat and redness Also increase permeability of veins and lymph vessels, which causes plasma and interstitial fluid to flood to infection site and gives swelling
What is ketoacidosis
excess acidity of blood Caused by increased number of ketone bodies found in the liver after prolonged periods of fasting (byproducts of fatty acid metabolism) 2/3 of ketones are used as energy for heart and brain, but cannot be used by the liver because it lacks enzyme Ketoacidosis can also be caused by DM because lack of insulin available for sugar uptake from blood causes liver to switch to fatty acids like you were fasting
Describe nucleotide excision repair
excision of oligonucleotides that includes several bases on either side of error. DNA polymerase and ligase will replace
Confounding variable
extraneous variable influencing variables being studied. Not part of expected correlation or causal pathway "Placebo effect"
Describe Hemiacetals/acetals and hemiketals/ketals and what they would be used for
hemiacetal and hemiketal have an -OR group and and -OH. Acetals and ketals have 2 -OR groups. They are primarily used as protecting groups for aldehyde/ketone functional groups (prevent reduction). After the desired reaction, treat with acidic conditions and they will return to original aldehyde/ketone
How are radicals formed
heterolytic cleavage of bonds during reactions that results in one electron from a pair on one species and the other electron from a pair on the other species
Role of lymph nodes in immune system
high concentration of B and T lymphocytes. Filters blood for pathogens
Sensitization
increased response to a stimulus after the stimulus has been presented multiple times. The conceptual opposite of habituation
Characteristics of transport proteins
integral proteins that span the entire width of the lipid bilayer. essentially create tunnels through the hydrophobic core
What is globalization
integration of individual economies and cultures into a more unified global economy and culture This would include things like free trade between nations, economic interdependence, ease of travel, and access to technology that tend to blur national boundaries and encourage globalization
Describe operant conditioning
learning to associate a behavior with a consequence using reinforcement or punishment of a voluntary behavior Everything in this hinges on consequences whereas in classical conditioning everything hinges on instincts
Describe classical conditioning
learning to associate one stimulus with one another instinctual responses depend on the automatic nature of some other reflex, instinct, or biological response
Describe brain waves, what their frequencies are, and what each of them relate to
level of consciousness on an EEG Alpha: (9-13Hz) very relaxed or meditation Beta: (14-40Hz) awake and alert Theta: (4-8Hz) light sleep Delta: (0.5-3.9Hz) Deep sleep
Characteristics of B-cells (memory and plasma)
lymphocytes that mature in bone marrow and lymph tissue and participate in humoral immunity. B-cells produce antibodies, T-cells DON'T Plasma cells: formed when a B-cell binds its matching antigen and is activated (with help of help T-cells) to undergo mitosis. Essentially act as "Antibody factories" making and secreting soluble copies of that antibody Memory: remain in the body, allowing immune system to mount a more efficient secondary immune response if there is a later infection by the same pathogen
What does the term heterotrophs mean
must eat the carbon that is needed to build macromolecules humans are heterotrophs
What are carcinogens
mutagenic chemicals that cause or promote cancer
What happens if there is no ATP present for sliding filament
myosin heads can't detach from actin and muscle is stuck in the contracted position This is called rigor --> Rigor Mortis
Characteristics of Leukocytes (2 subtypes)
normal cells with all organelles Granulocytes: neutrophils, eosinophils, basophils (live for hours to days) Agranulocytes: monocytes (macrophages) and lymphocytes --> live for months to years
Where does translation occur?
occurs in the cytoplasm on free floating ribosomes and on RER
Describe fatty acid synthesis
occurs primarily in the cytosol of liver cells Always occurs with the construction of 16C palmitic acid, which is the only fatty acid the human body can synthesize from scratch Then moves to smooth ER Is a source of acetyl-CoA via the citrate shuttle
What is base rate fallacy
occurs when representativeness heuristics are used in error Fail to take into account general information when dealing with specific cases
What do the suffixes ol, oic acid, and oate mean
ol=alcohol oic acid=carboxylic acid oate=ester
Olfactory pathway
olfactory sensory neurons (located in olfactory epithelium of upper nasal cavity) --> Olfactory Nerve (CNI) --> Olfactory bulb (forebrain) --> Higher-order brain centers (amygdala, hippocampus, orbitofrontal cortex, etc)
Describe trial and error approach to problem solving
only effective when relatively few options
What is fundamentalism?
religious movements focused on "returning to" or "preserving" pure, original, or unchanged values, teachings, or behaviors. Often a direct reaction to social change, especially modernization or secularization.
Prospective memory
remembering to perform a planned action or recall a planned intention at some future point in time
What is symbolic interactionism?
sees society as the product of everyday interactions among individuals. This differs from functionalism and conflict theory in that it focuses more on micro interactions. Says that humans will act towards things on the basis of the meanings they have for them; the meanings arise from the interactions with others; and the meanings are changed through interaction
What is the neighborhood effect
segregation of the elderly, disabled, minorities, or the poverty-stricken into neighborhoods or housing projects can lead to social exclusion and even social isolation, an extreme case where a person has no contact or nearly no contact with society
Describe static equilibrium compared to dynamic equilibrium
static equilibrium is objects at rest dynamic equilibrium is an object moving at constant velocity They both result in a net force of 0
What is ageism
stereotyping or discrimination based on one's age
Function of glomerulus
strains blood, allowing fluid, ions and molecules about the size of glucose or smaller to pass through to Bowman's capsule
What is maximum static friction
the friction created before an object begins to slide "breaking point"
Describe chromatin
the general term for DNA and protein together. Chromosomes are made up of chromatin
What is a social group
two (+) persons who interact with on another, share similar characteristics, and feel a sense of unity
What is hybridization
two complementary fragments cut by the same endonuclease join together
How does endocrine cellular communication function?
via hormone signaling: hormones are manufactured and secreted by cells in the endocrine system and then transported via bloodsteam to receptors on the cell surface (water-soluble) or inside the cell (lipid-soluble)
What is incomplete penetrance?
when various individuals all have identical genotypes and yet some have the disease phenotype and others do not
Describe mitosis and the phases
yields two genetically identical diploid daughter cells, which are also identical to the mother that produced them. Centromeres split. Prophase: nuclear membrane degenerates and chromosomes condense Metaphase: chromosomes line on the metaphase plate and the spindle apparatus is formed Anaphase: separation of chromosomes and migration toward opposite poles of cell Telophase: nuclear membranes begin to re-form and chromosomes unwind
What is intuition
"Gut feeling". Often based on previous experience, in which case, it is an example of unconsciously applying a heuristic or mental set
What are inorganic esters. Where are they found
Esters of acids (phosphoric acid, sulfuric acid, nitric acid) Inorganic triphosphates= ATP, GTP, UTP, etc Inorganic diphosphates=FADH2 and NADH Inorganic monophosphates=DNA, RNA, FMN
Electric force equation
F=qE (q=charge(mass); E=electric field strength(gravity)) Point charge: F=kq₁q₂/r²
Describe gas solubility
For gases dissolved in liquids: increasing temperature=decrease in solubility decrease temp=increase solubility Increasing the vapor pressure of a gas over a liquid will increase the solubility of the gas in that liquid (why soda is pressurized with CO₂
Many physiological processes have positive ∆G's, why?
For many anabolic and metabolic reactions, ∆G is positive. But this is due to reaction coupling in which the negative G of some steps will outweigh the positive G of other steps
Cerebral cortex (subdivision, embryological origin, and function)
Forebrain from the prosencephalon Is in charge of executive functions, complex perceptions and cognition
Myelin Sheath
G
List strong acids and what the breaking acid is
HI, HBr, HNO₃, HCl, HClO₄, HClO₃, H₂SO₄ The breaking acid is H₃O⁺; anything stronger is a strong acid and anything weaker is a weak acid Will dissociate 100% in water
What are the ideal gas assumptions
Ideal gas molecules have no volume and they have no intermolecular forces The identity of the gas doesn't matter if it is ideal, and the pressure is based on moles, NOT g or anything else
Describe significance levels
If p < 0.05=95%, confident results are real rather than the result of chance
What is the -ose suffix What does deoxy- mean
-ose is the suffix for all sugars deoxy= normal location of an -OH group is replaced with a Hydrogen
Intergenerational vs intragenerational social mobility
Intergenerational= change in social class by one or more members of a family between generations Intragenerational= change in social class by an individual within their lifespan
Mesyl/Tosyl
Intermediate added so there a functional group can be added later Tosylate has the benzene ring
Invasive and non-invasive methods of brain studying
Invasive= direct electrode stimulation (open cranium, during brain surgery), human brain injury case studies, extirpation of brain regions in lab animals Non-invasive= electroencephalography (EEG), transcranial direct current stimulation (TDCS), and regional cerebral blood flow (rCBF)
Maintenance Rehearsal vs Elaborative Rehearsal
Maintenance= repetitive rehearsal of new information without thinking about it (repeating, re-writing, re-reading) Elaborative=semantic rehearsal. Rehearsal of new info by thinking about its meaning, purpose, and relationship to previously known concepts
What is mass media and how does it effect cultural values
Mass media is the methods or instruments of conveying information that allow for communication with large numbers of people at once (television, radio, internet) Cultural values influence what the media presents; and what the media presents influences cultural values Cultural values↔Mass Media
Material vs Symbolic culture
Material culture is all symbolic artifacts created by members of a society. Anthropologists and archaeologists are primarily interested in studying material culture. Chairs, tables, smart phones, tablets. Symbolic culture is the ideas created by members of a society. Sociologists are primarily interested in studying non-material culture. Symbols, language, norms, values, and beliefs.
What is Gestalt therapy?
Max Wertheimer a humanistic approach to therapy emphasizing the treatment of the individual as a whole, rather than reducing a person to the sum of their individual behaviors, drives, or neuroses
Difference between memory and learning
Memory= storage and retrieval of information Learning= relatively long-lasting changes in behavior resulting from experience
Inferior Colliculi (subdivision, embryological origin, and function)
Midbrain from the mesencephalon controls auditory center, hearing reflexes
What is Dalton's Law of partial pressures? Describe how it would be used
P(total)=P₁+P₂+P₃.... If we add more gas (P₁) to existing mix of 3 gases, we increase partial pressure of gas 1 and total pressure, but have NO EFFECT on partial pressure of other gases
What is the general pressure formula. What are the units and conversions for pressure?
P=F/A 1x10⁵Pascals=1atm=760mmHg=760Torr
Elastic potential energy equation
PE=1/2kx²
What is the difference between personal unconscious and collective unconscious
Personal unconscious= part of our minds that we are not consciously aware of but that affect our behavior and can be revealed to us in our dreams Collective unconscious= portion of the unconscious that is inherited and contains universal themes through all of our lives
What is the trait theorist view of personality
Personality characteristics are part of a larger continuum of personality
What is the type theorist view of personality
Personality characteristics exist as discrete, fixed categories. Most people will fit into one category or another.
Phenotype vs. Genotype
Phenotype is the expression of the gene in terms of its visible or observable characteristics. Genotype refers to the specific alleles held by that individual
What is semi-conservative replication? Semi-discontinuos?
Semi-C: each newly formed daughter consists of one original strand paired with one newly replicated strand Semi-D: one strand is synthesized continuously and the other (lagging strand) is synthesized in Okazaki fragments
Describe the human memory flow
Sensory= <2 sec ST/Working= <30 sec
Describe Gel Electrophoresis and the two types used
Separates proteins based on size. Gel is placed in buffer with different ions that will conduct electricity DNA has a negatively charged backbone, so it will flow toward cathode (+) The smaller the fragment, the further down the gel it will run Agarose: used for separating bigger pieces of DNA (>50bp) SDS-PAGE: used for separating smaller DNA and proteins SDS= a detergent that denatures the protein and places negative charges
Difference between sex and gender
Sex is a biological matter. People are divided into two groups, either male or female. Biological differences are found in chromosomes, anatomy, and hormones. Gender is the personal traits and social positions that members of a society attach to being male or female. Gender is seen as being more socially constructed
Shaping vs extinction in operant conditioning
Shaping= form of an existing response is gradually changed across successive trials towards desired target behavior Extinction= when operant behavior that has been previously reinforced no longer produces reinforcing consequences the behavior gradually stops occurring.
Smooth ER function and characteristics
Site of lipid synthesis and modification; NOT metabolism (lipids are metabolized by the mitochondria)
What is bond dissociation energy?
The same as bond energy Stable molecules have high bond energy. If something is a "high energy molecule" molecule, then it has low bond energy
Describe the order of macromolecule metabolism in a healthy individual
Will burn carbohydrates first, then fats, then proteins Carbohydrates= 4kcal/g Fat=9kcal/g Proteins= 4kcal/g
General definition for a lipid give examples
a biomolecule that is hydrophobic includes fats, oils, waxes, sterols, fat-soluble vitamins, glycerides, phospholipids, and terpenes
Describe a peptide bond formation
a dehydration synthesis and acyl substitution the amine nitrogen (nucleophile) from the new amino acid attacks the carbonyl carbon (electrophile) on the C-terminus of the growing peptide chain Aided by enzymatic function of the ribosome
What is totalitarianism?
a government that takes total, centralized, state control over every aspect of public and private life. Most extreme form of authoritarianism. North Korea.
What is of Gastrin and its function?
a peptide hormone. Stimulates secretion of gastric juices and is secreted into the blood stream in response to food It is soluble in blood without a carrier, but does require a membrane receptor
What is the role playing effect
a person acting out a role is likely to internalize the attitudes associated with that role; shows that your behavior directly impacts the attitudes that you hold Best exhibited in the Zimbardo (Stanford) prison experiment
What is a subculture
a secondary culture existing within a mainstream culture that has its own set of values and norms, but is generally able to co-exist with mainstream culture
What is counterculture
a secondary culture that is antagonistic toward mainstream culture and has the overt goal of changing it. Countercultures are often political in nature because they are focused on enacting change.
What is the stereotype threat
a self-confirming concern that one will be evaluated based on a negative stereotype, or that their behavior will confirm the negative stereotype
What is a role in society
a set of expectations and norms that define how a person in a given status should behave
What is a social movement
a social movement is a large alliance of individuals who share a common interest in creating or blocking social or political change
What is a plutocracy?
a social system where the wealthy rule, in other words power by wealth. Could be considered some of the United States
What is secularization?
a societal transformation away from close identification with religious values or institutions, and toward non-religious, secular values or institutions
What is environmental justice
a state in which the benefits and burdens of interacting with the environment are equally distributed among all people independent of race, ethnicity or class. Lack of environmental justice is cited when wealthy segments are thought to primarily benefit from use of environmental resources while those of lower SES primarily bear the burdens of using those resources
Describe PTSD
a stressor-induced disorder developed after experiencing or witnessing a traumatic event such as a natural disaster, violent crime, or war. May include hyper-vigilance, reliving the event, anxiety, or avoidance
What does optically active mean
a substance that rotates plane-polarized light
Cannon-Bard theory of emotion
activation of SNS looks similar regardless of encountering threat or love of our life, so physiological arousal and emotional experience occur at the same time
Cortisol: location, class, function
adrenal cortex steroid/lipid-soluble a stress hormone; increases gluconeogenesis in the liver and thus blood glucose levels; stimulates fat breakdown
Hormones released by adrenal cortex (characteristics)
aldosterone and cortisol Are steroids and lipid-soluble
What is the work function in quantum terms?
amount of energy that is required to eject an electron from the surface of a solid metal KE=E-Φ E=hf (h=plancks constant; f=frequency)
Heat capacity (and equation)
amount of energy to be absorbed to give a unit change in temperature measured in J/K or cal/°C C=q/∆t (q=heat in J)
What is solubility
amount of solute that will dissolve in a given solution at a given temperature given in g/mL or mol/L
What is half-life
amount of time for exactly one half of the mass to disappear due to radioactive decay
What is a hydrate
an inorganic compound in which water molecules are permanently bound into crystalline structure
LH (location, class, function)
anterior pituitary peptide/water-soluble a surge in LH causes ovulation; stimulates the secretion of the sex hormones estrogen and testosterone
ACTH (location, class, fx)
anterior pituitary peptide/water-soluble stimulates adrenal cortex to release stress hormones called "glucocorticoids" NET EFFECT=increases blood glucose and inhibits glycolysis
What is a mutation? Point, missense, silent, frameshift, and neutral?
any change in DNA sequence Point: single base pair substitution Missense: mutation changes sequences so that a different codon is read Silent: any mutation that doesn't alter amino acid sequence Frameshift: mutation that alters the reading frame Neutral: doesn't alter the fitness of the individual
What is a reference group
any group to which a person normally compares themselves
Describe ideal, non-viscous fluid flow
assumed no friction between fluid and walls. Fluid near wall flows with the same velocity as fluid at the center of the pipe. Always assume this is the flow unless otherwise specified
How are magnetic fields created
by changing electric field and by current (moving charges) Any movement, velocity, rotation, etc of a charged particle causes a change in electric field, and thus the magnetic field as well Electric fields are also created by changing magnetic fields
Define sublimation (Freud)
channeling unacceptable thoughts or urges into something that is more acceptable. might be used by some artists who use some personal tragedy to energize them to create a new work of art
Define rationalization (Freud)
creating excuses to justify something that is unacceptable. A student who fails a class claims that the professor was impossible to understand
Weak acid/base characteristics
don't dissociate readily in solution pK >0 or K<1 Percent dissociation of weak acid/bases decreases in the presence of salts
Characteristics of surface proteins
don't enter hydrophobic core of bilayer, but instead are contained only on the polar surface of the plasma membrane AKA peripheral proteins
Describe what allosteric control is
downstream product inhibits an upstream enzyme. The eventual target molecule is often a major inhibitor that downregulates upstream products
Describe the problem-solving theory of dreaming
dreams are a way for mind to solve problems encountered while awake. Some proponents suggest the unconscious dreaming mind is better suited or more capable of solving problems than the awake mind. Unrestricted by reality or more sensitive to subtle clues
Role of fallopian tubes
ducts that utilize ciliated epithelium to transport egg from ovary to the uterus Fertilization usually occurs in one of the fallopian tubes
What are dyads, triads, and large groups
dyad=the smallest group size you can have. tend to be emotional and unstable. Dissolved if one person leaves triad=added stability from dyad. 3rd person often mediates disputes, and this is more likely to survive as group size increase, stability and longevity increase, but intimacy, loyalty, bonding, sense of responsibility, level of individual contribution and consensus all decline.
Describe brain specific metabolism
glucose during well fed state; glucose if fasting; ketones if prolonged fasting or starvation
Describe Triacylglycerol (kinds)
glycerol backbone with 3 fatty acids attached via an ester linkage AKA triglycerides Saturated: no double bonds Unsaturated: at least one double bond
Characteristics of eosinophils
granulocyte Recruited to areas of parasitic invasion, particularly multicellular parasites, where they release their granules containing peroxidases and other enzymes that digest tissue --> This destroys pathogens but also host tissue
Dementia
group of symptoms affecting memory, thinking, and social ability
Hormones released by the embryo/placenta (characteristics)
hCG (human chorionic gonadotropin) Peptide and water-soluble
What is chirality
handedness any atom attached to 4 different substituents=chiral
Describe simple distillation
heat mixtures in a flask. The liquid with the lower boiling point will evaporate first, and enter the collecting arm/condenser, where it is cooled (by the water flowing through), and then will drip into collecting flask. For this to work, the two substances must have boiling points that are at least 25 degrees C apart.
Emotional interference in memory
heightened emotions with respect to one memory can simultaneously increase the strength of LTM trace and decrease the strength of other memories occurring before, at the same time, or after that event
What is the bystander effect
help to a victim is withheld in situations in which there are other people around (Kitty Genovese: attacked and murdered with multiple people watching)
Things to remember for projectile motion
horizontal velocity never changes, and horizontal acceleration=0 Vertical acceleration always=10m/s² ↓ Vertical behavior is exactly symmetrical Time in the air depends only on the vertical component
What is Pascal's Law?
pressure is transmitted in all directions, undiminished, through a contained, incompressible fluid If pressure increases at any point, it increases same amount everywhere
Describe ethanol fermentation
primarily happens in yeast and a few bacteria. EtOH is produced and is the final electron acceptor. Pyruvate (3 Carbons) is changed into ethanol (2 Carbons) and CO₂
Describe Hoffman degradation
primary amides will react in strong, basic solution of Cl2 or Br2 to form primary amines. This shortens the length of carbon chain
Describe the differences between primary, secondary and tertiary amides
primary and secondary can H bond and are water soluble as long as they lack long alkyl chains tertiary amides cannot H bond
What are neuropeptides. Compare to neurotransmitters
neuro-active peptides whose function is similar to that of neurotransmitters. Endorphins are one example Neurotransmitters are faster and have more short-lived effects Neuropeptides are slower and have longer lasting effects
Describe beta decay
neutron is changed into proton with the ejection of an electron
Describe the Pauli exclusion principle
no 2 electrons can have the exact same 4 quantum numbers
What is a zero-sum game
one's own gain is balanced by the losses of another
What is antigen presentation
process by which a cell that has engulfed an antigen or microbe via endocytosis or phagocytosis takes protein segments of that microbe, and "presents" them on major histocompatibility complex (MHC) proteins
Describe what the Grignard synthesis is
production of an alcohol with extension of carbon chain by adding an organometallic (R-MgX) Can also be done with other electrophilic double bonds (C=N, S=O, N=O)
Cilia characteristics and function. Found where?
protrusions on lumen-facing side of epithelial cells lining various cavities in the body is NOT used for locomotion, but rather to move fluid or extracellular materials past the cell Exclusively in respiratory system (lungs), Nervous System (ependymal cells that line ventricles of brain), and reproductive system (cells that line the fallopian tubes)
Describe a simple machine and the types
reduce the amount of force necessary to perform a given amount of work. NEVER reduce or change the amount of work Ramps, levers, pulleys, hydraulic lifts,
What is a centromere
region of the chromosome that joins the sister-chromatids
What is kinship? What are the 3 levels?
relationships derived from descent and marriage. Can be both voluntary and involuntary Primary kin= a person belonging to the same nuclear family as the ego (father, mother, sister, brother, wife, husband, son, daughter) Secondary kin= primary kin of ego's primary kin. 33 potential, just think about them Tertiary kin= primary kin of secondary kin. 131 possibilities including great-grandparents, first cousins, spouses of nieces nephews aunts and uncles
Role of seminal vesicles
release a majority of fluids that make up semen, including fructose and alkaline fluids that make semen basic
What is civil unrest in relation to globalization
results from globalization because some theorists propose that globalization creates global inequality by making the entire world a single capitalist market. Globalization can also make previously isolated groups aware of their relative deprivation compared to others around the world, leading to uprising
What are structural isomers
same formula but different bond-to-bond connectivity 2-methylpentane vs 3-methylpentane (C6H14)
What is specific rotation
takes variable factors from the observed rotation (concentration, tube length) into account by dividing rotation by tube length and concentration "observed rotation per length, per concentration unit)
What is urbanization
tendency of a population to move away from rural or agricultural settings and be concentrated in urban settings, usually because of the lure of economic opportunity. Global trade and economic exchange is often centralized in one particular city within each country, resulting in hyperurbanization of cities such as New York City, Tokyo, or Hong Kong
What is difraction
tendency of light to spread out as it goes around a corner of through a slit
What is the just-world hypothesis
tendency to believe that people get what they deserve
What is Libido
the "psychic energy" created by the survival and sexual instincts. It is part of the Id, and is considered by Freud to be the driving influence of all behavior
What is tertiary protein structure
the geometric, 3-D folding of alpha helices, beta sheets, and other moieties to form functional globular or structural protein
Hydrophobic vs Hydrophilic parts of protein folding
the hydrophobic R groups fold into the interior of globular protein to escape water. Will also bring smaller polar groups with them to interior The majority of R groups on the surface of globular protein are either polar or uncharged
Experience-based influence on behavior
the influence of experience on behavior would include EVERYTHING that is not genetic; learning, conditioning, socializing, one's environment, and any other experience you in encounter in life
What is valence (C, N, O, F)
the number of bonds that an atom "normally" makes Carbon= tetravalent, N=trivalent, O=divalent, F=monovalent
What is mortality rate? Total, crude, age-specific?
the number of deaths per unit time Total mortality rate=number of deaths in a year within a given population Crude mortality rate= total number of deaths per year per 1000 people Age-Specific mortality rate= total number of deaths to residents of a specified age or age group in a specified geographic area divided by the population of the same age or age group in the same geographic area for a specified period of time multiplied by 100,000
What is global inequality
the same inequalities already discussed, but applied to a global scale. Countries are stratified according to resources, economic strength, and wealth (GDP)
Hybridization and how to calculate
the sp numbers calculate by counting the number of sigma bonds and the number of pairs of unbonded electrons and adding. The number will be the sum of the superscripts. (2 sigma bonds and 2 lone pairs [water]=sp3)
What is the illness experience?
the ways in which individuals define and adapt to a perceived lack of good health
Black body radiator
theoretically absorbs all energy and emits 100% of it's energy as electromagnetic radiation
What is the World Systems theory? Core, peripheral, and semi-peripheral countries?
theory emphasized a global inequality that is similar to the stratified inequality present in individual societies. Core countries dominate and exploit peripheral countries for labor and raw material. Peripheral countries are dependent on core countries, especially for capital Semi-peripheral countries feature characteristics of both core and peripheral countries
What happens if there is no Ca during sliding filament model
there is an inability to contract. This is called flacidity
What is the general diagnostic rule of psychological disorders
to be diagnosed affirmatively, the symptoms of almost any disorder must cause clinically significant distress OR impairment in normal functioning (familial, social, occupational, etc)
What are collectives (examples)
unplanned activity among large number of people that may result in social change often controversial; examples include Fads, Mass Hysteria, and Riots
Describe algorithmic approach to problem solving
uses mathematical formulas, or step-by-step flowchart-like approach
How to protect alcohols
using TMS (trimethylsilyl) or MOM (methoxymethyl ether) to preserve the single Oxygen bond
What is the typicality effect
using a typical example of a concept increases recall or verification rate over using a less-typical example "A robin is a bird" vs "a penguin is a bird"
Describe gamma emission
usually emitted as a byproduct of the types of other types of decay; doesn't change the number of nucleons
Describe second messenger systems
usually occur via a cascade: one hormone activates another hormone, enzyme, or signaling molecule. This then activates another, etc. G-proteins are a prime example
Describe the process of fertilization
usually occurs in fallopian tubes. Sperm and egg are traveling toward one another generally meet here Implantation normally occurs in the uterus but can occur in the fallopian tubes, leading to ectopic pregnancy
What are the 7 senses tested about on the MCAT
vision, hearing, somatosensation, taste, smell, kinesthetic sense, vestibulocochlear sense
What is parallel processing (vision)
visual system processes different aspects of the visual world in separate stream of information motion and color are processed in different areas
What is the fundamental attribution error?
we are generally more likely to make dispositional attributions about undesirable behavior observed by others, rather than situational That person cut across the lane because he is a bad driver, not because he was in a bad situation
What is the prisoner's dilemma
will you turn the other prisoner in to get off free. If both deny, they both get a short sentence. If they both betray, they both get a long sentence. One denies and one betrays= one does a long time, the other goes free
Define acceleration
how quickly a velocity is changing. If there is no net force, there can never be acceleration ∆v/t
What is self-presentation? Impression management?
how we present or display ourselves to society impression management is "presenting oneself", and implies that the representation of ourselves is not always genuine. Individuals will attempt to shape, manipulate and manage how they are perceived (front stage vs back stage self)
Describe how two lens systems work
image formed by the first lens becomes object for second lens (binoculars, telescope) Magnification: M=m₁m₂ Power: P=P₁+P₂
Lysosome function and characteristics
pH of 5 digests cell parts and fuses with phagocytotic vesicles. Participates in cell death They are formed by budding from the golgi
How does pH, temperature, substrate concentration, and enzyme concentration effect enzyme reaction rate?
pH: changes in either direction will disrupt the H-bonding of enzyme and enzyme substrate complex Temp: mild increases will increase rate, but too much will denature Substrate Conc: at low conc, reaction rate will increase rapidly, but as it becomes saturated the rate will drop off Enzyme Conc: same as substrate
Henderson-Hasselbalch Equation
pH=pKa-log[HA]/[A-]
Insulin: location, class, function
pancreas islet cells peptide/water-soluble stimulates uptake and storage of glucose from the blood (causes cells to uptake glucose)
Parathyroid hormone: location, class, function
parathyroid peptide/water-soluble increases blood calcium by stimulating proliferation of osteoclasts, uptake of Ca2+ in the gut, and reabsorption of Ca2+ in the kidney
Describe the parts of a carbonyl functional group that are distinctive
partial positive charge on carbonyl carbon (makes carbon a good electrophile) Alpha hydrogens (on the C immediately adjacent) In sp2 planar, which allows the carbonyl C to be attacked from either side (allows for R and S enantiomers)
What is rational choice theory?
see's all actions as fundamentally rational and people ascertain the costs and benefits of any action prior to acting. Actions are rationally motivated despite appearing otherwise. Similar to the exchange theory in the cost benefit analysis, but differs with an emphasis on the individual action rationally
What is a structural functionalists view
sees society as a complex system whose parts work together to promote solidarity and stability
What is a vector
segment of DNA used to transfer a desired sequence to another
Peroxisomes function and characteristics
self-replicate detoxify hydrogen peroxide using catalase into water and oxygen participate in lipid metabolism
Semiconductor vs superconductor
semiconductor= material right in the middle of an insulator and conductor superconductor=under very precise conditions is thought to exhibit zero resistance to electron flow
Describe how chromatography (generally) works
separation of 1 or more compounds by dissolving them in a mobile phase, and passing that phase across the stationary phase The first substance out/ the substance that moves the furthest is the LEAST POLAR
What is conformity
individuals alter their behaviors or attitudes to "fit in" a social context passive influence that others have on our behavior
What is social identity theory?
individuals derive pride and self-esteem from group memberships As a result, individuals always strive to increase the status of the group they belong and will discriminate against out-groups
What is social facilitation?
individuals will perform better on simple tasks when being observed by others (simple=tasks in which one is already proficient) Will perform worse on complex tasks when being observed by others (complex= tasks that are still new or difficult)
Procedural memory (examples)
knowing how to do things (motor skills) walking, talking, riding a bike
Intracellular receptors (endocrine): describe
lipid-soluble hormones (steroids) don't require plasma membrane surface receptor; they dissolve through the membrane and bind targets in the cytosol instead. In most cases the activated target acts inside the nucleus on promotor region of a gene
role of thymus in immune system
location where T-lymphocytes acquire immunocompetence, differentiate, and mature
What are telomeres
long sections of repetitive DNA nucleotides found at both ends of each chromosome they are the buffer regions of non-coding DNA so that repetitive losses in length don't affect a gene sequence ~50 replication cycles will consume all of telomere; then there starts to be some loss of gene sequence
What is the expectancy-value theory of emotion
magnitude of motivation to engage in a behavior is a function of an interplay between an individuals expectation of success and perception of relative value of rewards associated with success
Role of the tesicles
make, nurture, and store sperm
Memory vs learning
memory is encoding, storage, and retrieval of information Learning is relatively stable changes in behavior based on experience
Alzheimer's Disease (describe)
memory loss, impaired cognition, and language deterioration. Onset is usually ~65 or > β-amyloid peptides accumulate outside the cell and Tau proteins aggregate into insoluble neurofibrillary tangles inside the cell
Biological influences on cognitive development
metabolic or other biological conditions can alter cognition or cause brain damage
What is the threshold potential
minimum stimulus that must be exerted on membrane to initiate full action potential. Is usually somewhere around -55mV. If a stimulus depolarizes membrane above this threshold, the entire action potential will follow; if not it will return to -70mV
What is an anomer
molecules that differ only in spatial orientation at the anomeric carbon of a ring structure
What is a secure attachment? What are childhoods like and what are adults like
most developmentally healthy form of attachment childhood has a constant caregiver present. Prefers their caregiver but can be comforted by strangers. They are going to be visibly upset when their caregiver leaves, and comforted when they return Adults are going to be trusting, have lasting relationships, high self-esteem, and comfortable with sharing feelings
aortic valve
11
What is mRNA
complementary RNA strand copied from DNA template
aortic arch
12
bicuspid valve (mitral)
12
What is the difference between Active Transport and Secondary Active Transport
Active transport requires ATP, secondary does not require ATP to be coupled
Group/family in period table
The vertical column (similar qualities)
What are purines vs pyrimidines? How many bonds between each?
There are 2 hydrogen bonds between adenine and thymine or uracil There are 3 hydrogen bonds between guanine and cytosine
What is the appraisal model of emotional expression
There are cognitive appraisals of a given event that result in emotional response similar to the basic model (universality) in that they both suggest biologically programmed emotional responses
Role of R groups in amino acids
They are what participate in chemistry: combination of R groups almost exclusively determines chemistry and folding patter
What is refraction
bending of light at an interface between 2 medium with different indices of refraction
What is a phenyl group
benzene attached directly to a primary chain
Culture influence on cognitive development
different expectations and traditions will reward different behaviors because of different values
Environmental influence on cognitive development
different parents styles can reward different behaviors; exposure to environmental chemicals or toxins can effect; fetal environment (fetal alcohol syndrome)
What are dyssomnias?
difficulty falling asleep, staying asleep, or avoiding sleep
Describe transverse waves
disturbance is perpendicular to direction of travel (waves on a string)
What is a manic episode
experience marked by dramatically elevated mood, decreased need for sleep, increased energy, inflated self-esteem, increased talkativeness, and irresponsible behavior. In bipolar disorder, this is the main criteria; whereas depression is not included in the DSM criteria
Amygdala (location and function)
forebrain (part of the limbic system) emotion, motivation, implicit emotional memory
What are plane mirrors
Regular mirrors; image and object will always be equal distance on either side of the mirror
Describe the reaction of alcohols with PBr3
Removes the alcohol group and replaces with Br
Describe reaction of alcohols with SOCl2
Removes the alcohol group and replaces with Cl (occurs in pyridine)
What is resting potential
-70mV Voltage across membrane when action potential is NOT present
What are the 4 bone types
Long= femur, humerus Short= tarsals, carpals Flat= skull, sternum Irregular= hip, vertebrae
Describe the first steps of Glycolsysis (1-5)
1. Glucose → Glucose 6-Phosphate (via hexokinase; Uses ATP, gives off ADP) 2. Glucose 6-Phosphate → Fructose 6-Phosphate (via phosphoglucose isomerase) 3. Fructose 6-Phosphate → Fructose 1,6-Bisphosphate (via phosphofructokinase; uses ATP, gives off ADP) 4. Fructose 1,6-Bisphosphate→ Glyceraldehyde 3-Phosphate OR Dihydroxyacetone Phosphate (via Aldolase) 5. Dihydroxyacetone Phosphate → Glyceraldehyde 3-Phosphate (via triose phosphate isomerase)
Sin of 0, 30 Cos of 0, 30
0, 1/2 1, √3/2
Steps of cellular respiration
1. Glycolysis: in the cytoplasm. Splits glucose into 2 pyruvate 2. Pyruvate dehydrogenase complex: converts pyruvate to acetyl-CoA; happens in the mitochondrial matrix 3. Acetyl-CoA converted to NADH and FADH2 (via many steps). NADH and FADH2 are going to then be used as the electron carriers. Occurs in the mitochondrial matrix 4. Electron Transport Chain: happens on the inner mitochondrial membrane. Ultimately makes ATP from electrons of NADH and FADH2
What are the 3 stages in response to stress
1. Alarm stage 2. Resistance stage 3. Exhaustion stage
left pulmonary veins
11
Describe a Galvanic Cell
AKA Voltaic cells Convert chemical energy into electric energy using difference in reduction potentials in 2 metals to create a current along a wire Requires a salt bridge that allows sulfate to flow to Zn area to neutralize (+) charge and allow K+ and Cu2- area to neutralize negative buildup Cu side will become more reduced (gain electrons) because it is more electronegative than Zn Can be created with any two metals, regardless of reduction potential Cathode=positive; Anode=negative
What is the difference between aldose and ketose sugars?
Aldose sugars have an R-OH on ONLY one side of the ring oxygen (glucose, ribose, deoxyribose) Ketose sugars have an R-OH on only one side of the ring oxygen (fructose)
Stimulates (subclasses and effects)
Amphetamines, cocaine, ecstasy Stimulates CNS. Feel euphoria and high levels of energy. Have a higher HR and RR Amphetamine and coke act as agonists of monoamine neurotransmitters with their effects on dopamine activity receiving the most attention. Both will block dopamine reuptake, but amphetamine causes additional release
Describe a competitive inhibitor, its effects on variables, and an example
An inhibitor that binds at the active site. The inhibitor will resemble the substrate in shape. Can be overcome by increasing concentration of substrates Vmax= no change Km= increase Statin Drugs: HMG-CoA reductase inhibitors that occupy HMG-CoA reductases active site and preventing HMG-CoA from entering and being converted to mevalonic acid.
Describe an oxidation-reduction reaction. What does oxidized mean? Reduced?
Any reaction where 1(+) electrons are transferred from one atom to another Oxidized= atom that loses electrons; reducing agent Reduced= atom that gains electrons; oxidizing agent
Fluid flow through capillaries (arterial vs venous side)
Arterial side: higher hydrostatic pressure, lower osmotic pressure. Hydrostatic force essentially pushes the fluid like a pump from the heart Venous side: Higher osmotic pressure, lower hydrostatic pressure. Acts like a vacuum and pulls water from interstitial fluids back into the veins
Characteristics of arteries and veins
Arteries leave the heart, veins return to the heart doesn't matter if if they are carrying oxygenated or deoxygenated blood
Describe the fructose metabolism feeder pathway for glycolysis
At the muscle and kidneys: Hexokinase converts Fructose to Fructose-6P, which then feeds into the 3rd step of glycolysis At the liver: Fructokinase converts fructose to Fructose-1P. Fructose-1P Aldolase then converts Fructose-1P to Gylceraldehyde-3P and Dihydroxyacetone-P (DHAP). Triose phosphate isomerase then converts DHAP to glyceraldehyde-3P, which then feeds into step 5 of glycolysis
Describe how acquired immunity from a B cell works
B-cells will mature in bone marrow or lymph tissue. Each produces only one kind of protein receptor on it's membrane called an "antibody"; Each antibody will recognize and bind only one foreign particle (antigen) If antigen binds to B-cells antibody, the B-cell will undergo differentiation into a plasma cell and a memory B-cell Plasma cell's manufacture free antibodies and release them into the blood; whereas memory B-cells multiply and remain in blood, preparing body for a second response
Acid derivates: what are the best leaving groups, and what are the most stable
Best leaving: :-Cl > -OCOR > -OH > -OR > -NH2 Stability: Amides > Esters > Carboxylic acids > anhydrides > acid chlorides
What is co-dominance?
Both phenotypes are fully expressed at the same time in a heterozygote (Red and white give red and white striped flower)
Bottom-up vs Top-down processing
Bottom-up: taking individual elements and putting them together to make a whole (looking at a picture and just seeing irregular dark spots based on perceiving the visual stimulus) Top-down: involves cognitive factors influencing the way in which components are processed (seeing the spots after being told it's a dog)
Describe the organization of skeletal muscles
Bundle of many __fasciculi__ make up a muscle group. Each fasciculi is a bundle of many long tubular cells called __muscle fibers__. Around each muscle cell is a specialized cell membrane called __sarcolemma__. __Myofibrils__ are long bundles of proteins composed primarily of actin and myosin fibers. __Sarcomeres__ are repeating units of actin and myosin fibers The __sarcoplasmic reticulum__ is bundles of interwoven myofibrils. The SR stores and releases Ca2+ ton initiate contraction sequence.
Axon
C
What are common oxidizing agents
O₃ (ozone), Cr₂O₇ (dichromate), CrO₄ (chromate), KMnO₄ (potassium permanganate), Jones Reagent, Collins reagent, PCC, PDC
Equation for capacitor in circuit and potential energy of a capacitor
C=Q/V (C=farad) PE: U=1/2CV²
Circumference of a circle equation
C=πd or C=2πr
Benzyl
CH2 directly attachd to a benzene ring with an R off of the CH2
Amino Acid stereocenter characteristics
Called the α-carbon all have a stereocenter except for glycine (2H). Contain 4 substituents: R, H, Carboxylic acid, and amine All amino acids are S except Glycine (no stereo) and Cysteine (Sulfur makes it R)
Describe a 1,3 dicarbonyl and it's keto-enol properties
Can act as an H-bond donor (whereas normal aldehydes/ketones cannot be H-bond acceptors). Th H bond between the alcohol and carbonyl O stabilize the enol form
Difference between cation and anion
Cation has fewer electrons than protons (+ charge): Corresponds to metals Anion has more electrons than protons (- charge: Corresponds to non-metals Cations are smaller, because less cloud space; Anions larger
What is nondisjunction and examples
Chromosomes fail to separate during anaphase. This can occur during meiosis I or II or mitosis, but is most common during meiosis I This will result in daughter cell having too many/too few chromosomes Turner's Syndrome: monosomy X chromosome Down Syndrome: Trisomy 21
Chlorite
ClO₂⁻
Chlorate
ClO₃⁻
Describe the difference between controlled processing and automatic processing
Controlled processing requires attention, whereas automatic processing does not Driving a car: first learning, requires a lot of attention, but as tasks become more well-learned process becomes more active and requires less active attention. Leads to being able to drive a car and hold a conversation at the same time
What is the DSM-5? Describe how it's used
Diagnostic and Statistical Manual of Mental Disorders Volume 5 the official reference manual mental health professionals and physicians use to diagnose mental disorders in the United States Is based on symptoms ONLY, not causes or treatments. Most disorders are a list of possible symptoms and the exact criteria for diagnosis are predetermined (e.g. three or more of the following, persisting for a period of at least 6 months)
What is mosaicism?
Different cells in the same individual contain non-identical phenotypes
What is effusion? Diffusion?
Diffusion=process by which gas molecules spread from high concentration to low concentration due to random motion imparted as kinetic energy and collisions with other molecules Effusion=Diffusion of gas particles through a pin hole
Energy of a photon equation
E=hf (h=plancks constant) E=hv/λ (derived)
Describe an E1 reaction and the qualities around it
Elimination, first order 2 steps: dissociation of leaving group forms carbocation (slow); abstraction of proton with collapse of electrons to form double bond (fast) Favored by basic nucleophile and tertiary carbons only; polar protic solvents
Describe an E2 reaction and the qualities around it
Elimination, second order single-step abstraction of proton with the collapse of electrons to form a double bond and ejection of leaving Favored by strong and/or bulky bases
Two reactions to Negative Reinforcement in Operant Conditioning (and what they are)
Escape Learning- Subject adopts behavior to reduce or end and unpleasant stimulus Avoidance Learning- subject adopts a behavior to avoid an unpleasant stimulus in the future
Properties and description for ∆H(rxn)
Essentially the bond energy: If a bond is broken=(+)H because energy is required; If a bond is formed=(-)H because energy is released switch signs if a reaction proceeds in opposite direction, and multiply if stoichiometric numbers appear
Temporal lobe is responsible for
Hearing and facial recognition
Incidence vs Prevalence
Incidence= measure of a disease that allows a person's probability of being diagnosed with a disease during a given period of time. Incidence rate is number of new cases of a disease divided by number of persons at risk for the disease Prevalence= measure of a disease that allows us to determine a persons likelihood of having a disease. Prevalence rate is the total number of disease in an existing population divided by a total population
Differences between Jung and Freud on libido
Jung= Libido is generalized psychic energy, not exclusively sexual Freud= Libido is the driving psychic energy of the Id that is primarily sexual
Differences between Jung and Freud on behavior?
Jung= behavior is caused by past experiences (from childhood or adulthood) and future aspirations Freud= behavior is caused by repressed desires from childhood
Difference between phosphorylase, kinase, and phosphatase
Kinase transfers a phosphate from a high energy molecule like ATP to other molecules Phosphorylase transfers a phosphate group from inorganic phosphate to another molecule Phosphatase removes a phosphate group from a molecule
Left hemisphere vs right hemisphere
Left is thought to be more important for linguistic processing in most people Right is considered non-dominant for most individuals. Is more important in visuospatial processing and in the processing of certain kinds of emotional information
Solubility, BP, and bonding characteristics of Aldehydes/Ketones
More soluble in water than alkanes. More polar than alkanes, less polar than alcohols Higher BP than alkanes, lower BP than alcohols Aldehydes and ketones can act as hydrogen bond acceptors, NOT donors Function as electrophiles (Carbonyl C attacked by nucleophile) Also function as lewis acids, accepting electrons when a base extracts an alpha H *Aldehyde Alpha H is more acidic than ketone
Describe alpha vs beta anomers
OH/OR group and CH2OH are on same side=beta Opposite sides=alpha
What is a representative heuristic
Reliance on prototypes or stereotypes as a shortcut to making a decision or judgement
Describe the roll of the limbic system and where it is
Region of the brain most directly tied to emotion Ventral and prefrontal cortex is also involved; left processes positive emotion and right processes negative emotions LIMBIC= EMOTION and MOTIVATION
Positive/Negative Reinforcement/Punishment in Operant Conditioning
Positive Reinforcement= addition of reinforcing stimulus Positive Punishment= presenting negative consequences after undesired behavior Negative Reinforcement= removing, stopping, or avoiding negative outcome Negative Punishment= removing a favored item or stimulus from individuals life
Describe IQ correlations (based on outside factors)
Positive correlation with higher level of parent expectation Positive correlation with higher level of socioeconomic status Positive correlation with early education intervention Positive correlation with adequate nutrition
Power without consent vs Power with consent
Power without consent is force, coercion, and tyrannical forms of government such as totalitarianism. Are said to have little or no legitimacy. Power with consent are authority dependent uses of power, such as democratic forms of government that require the consent of the governed. Are said to have a high level of legitimacy.
What is the difference between power and authority
Power= the ability to attain one's desires or goals, even in the face of opposition Authority= the legitimate, approved use of power by a leader over person's who recognize, or have granted, that power to the aforementioned leader.
What are self-schemas
Pre-existing, organized patterns of thought about oneself that is used to categorize or process information. Can be helpful, but can cause bias or omission My cognitive framework about myself; how my ideas of who i am are used to categorize new information
What is the role of the immune system
Protect the body from infection and disease; destroy pathogens invading the body
What is proximity, similarity, and good Gestalt (Gestalt)
Proximity: objects/shapes close to one another appear to form groups Similarity: perception sees stimuli that physically resemble each other as part of the same object Good Gestalt: elements of objects are perceptually grouped together if they form a pattern that is regular, simple, and orderly.
What are the types of reversible inhibition? Irreversible?
Reversible= competitive, uncompetitive, non-competitive, and mixed Irreversible= inhibitor that binds covalently to enzyme and/or active site, disabling enzyme for prolonged time or permanently
What is a southern blot? Northern? Western?
Southern: used to verify the presence/absence of specific DNA sequences. Also indicates the relative size of restriction fragments Northern: identical to southern, but used on RNA instead of DNA Western: Used on protein segments instead of nucleotide segments. Probes used are radiolabeled antibodies rather than nucleotide sequences. Eastern: same as western, but used to verify post-translational modifications
What are the 4 stages of demographic transition
Stage 1. Pre-industrial society (high fertility, high mortality) Stage 2. Still pre-industrial (decreasing mortality rate as a result of societal improvements like sanitation, healthcare, and nutrition) Stage 3. Shift from agricultural toward industrial (decreasing fertility rate as a result of contraception, women's rights, and smaller family size) Stage 4. Industrial society (low fertility, low mortality)
What does non-volatile mean?
Substance does not form a vapor, or has an extremely low vapor pressure at RT
What is cell potential (EMF or E°cell)?
Sum of electrical potentials for the two half reactions that make up an electrochemical cell (half reactions will always come in pairs, with on oxidation half and one reduction half. --> the reduction half is the only one given, the oxidation is just the reverse) Stoichiometry doesn't apply here. 1 mol of Cu2+ has the same reduction potential as 2 mol Cu2+
Superordinate links vs modifier links in semantic networks
Superordinate: connect the concept to a category name, indicating that the concept is a member of a larger class (Cat-->mammal) Modifier: connect a concept to it's properties (Cat--> whiskers)
What is symmetry, past experience, and convexity (gestalt principle)
Symmetry: elements that are symmetrical tend to be perceived as a unified group Past experience: this is the weakest; conclusions are drawn based on observer's past Convexity: smaller of two overlapping objects is commonly interpreted as figure
2 divisions of the motor nervous system (describe)
Sympathetic: fight or flight. Cell bodies are located far from effectors. Neurotransmitters are acetylcholine at ganglia and norepinephrine at effector Parasympathetic: rest and digest. Cell bodies are located very close to, or inside, the effectors. Neurotransmitter is acetylcholine at both ganglia and effector
Hormones released by thyroid (characteristics)
T3 (triiodothyronine) and T4 (thyroxine) Are tyrosine derivatives and lipid soluble
What is the psychological construction model of emotional expression
Takes into account the universal responses, but also looks at a host of psychological factors including previous experience, mood, and language
What is the function of the liver
The "metabolic brain" of the human body. Regulates blood concentration of many different solutes. -Produces bile -Filters blood to remove toxins, drugs, bacteria -Produces blood plasma proteins (albumin, prothrombin, and fibrinogen) -Regulates amino acid levels in blood -Produces cholesterol and lipoproteins and packages them for transport (LDL, HDL, etc)
Describe G0 phase and it's characteristics
The "non-proliferative" or "rest" phase Fully differentiated neurons and cardiac muscle cells are frozen here as they dont divide anymore. Multi-nucleated skeletal muscles can also be considered in G0 phase. Also called "quiescent" which means that they are stable, unchanging, and unlikely to change.
Compare filtrate from the beginning to the end of the loop of henle
The beginning: more concentrated The end: less concentrated but also has much less volume (saves water) Loop of henle ultimately saves water
Describe Coulomb's Law
The electrostatic (gravitational) attraction between 2 charges F=Ke|q₁q₂|/r² Ke≈9x10⁹N(m²)/C²
Definition of glycolysis
The first step in the breakdown of glucose to extract energy for cellular metabolism
Is the human body an open or closed system?
The human body on a macro level is considered to be an open system. However on the cellular level, it is considered to be a closed system because the cells can exchange energy but not mass with the surroundings
Where are transition metals on periodic table
The middle, below stairs
Why doesn't the stomach digest itself?
The stomach wall is protected by large amounts of mucus from mucus cells
What is the dynamic steady state?
The system will stay in a constant state over time, but this requires continual work. Not in equilibrium with surrounding. Your body maintains a constant 98.6°F, despite the air temperature being at 75°
Describe alpha-beta unsaturated carbonyls
They will rearrange, acting as an electrophile. There will be a (+) charge on the beta carbon and a (-) on the carbonyl O, allowing it to become an oxygen
Describe the sarcomere (Thick, thin, A, I, H, Z, M)
Thick filaments: made of myosin Thin filaments: microfilaments and polymers of actin. Feature troponin and tropomyosin A band: runs the length of the myosin filament; does NOT change during contraction I band: distance between the ends of myosin filaments in one sarcomere to ends in next sarcomere. WILL shorten during contraction. H Zone: distance between ends of actin filaments. Shortens during contraction Z Lines: appear as zigzag lines that define the edges of each individual sarcomere unit. Actin filaments are anchored here by protein connection and stretch out in both directions. During contraction, distance between Z-lines shortens as sarcomere shortens M Line: center of myosin filaments. Distance between M lines between 2 sarcomeres will decrease during contraction
T3 and T4 roles in carbohydrate metabolism
Thyroid hormones increase basal metabolic rates; both secreted by thyroid in response to TSH from anterior pituitary
Describe hypnosis
Trance-like state under which a person becomes highly suggestible. Induced by a therapist and can serve to recall repressed memories, control pain, or stop undesirable behavior (weight loss, addictions)
What is fixation (freud)?
Unable to resolve issues at any given stage. Oral fixation could lead to seeking oral stimulation as an adult (smoking, overeating)
Describe oxidative phosphorylation
Uses ATP synthase to create ATP from proton gradient Uses protons from NADH and FADH2 in Krebs cycle. The Krebs cycle occurs in the mitochondrial matrix and the ETC occurs crossing the inner membrane to the intermembrane space; via proteins embedded in the inner membrane H+ are pumped out and NAD+ stays in the mitochondrial matrix, giving a proton gradient built up in the inner membrane space
Describe a virus
acellular, can't grow, survive or reproduce on own; require a host contain some form of DNA or RNA (not both) plus proteins
Lewis acid/base
acids accept a pair of electrons, bases donate a pair of electrons
What is inertia?
ability of an object to resist change to it's velocity; mass is a measure of an object's inertia
What is the cocktail party effect
ability to attend to only one thing with attention, but suddenly shift to something that was previously ignored because of a cue that draws our attention "Having a conversation at a cocktail party and drowning out all other conversations, but quickly shifting our focus because we hear someone else say our name"
What are pragmatics?
ability to competently use language appropriately in any given social context
What is power (social class)
ability to control others, events, or resources To make happen what one wants despite having obstacles or opposition
Function of collecting duct
carries filtrate through medulla toward renal pelvis. Is very permeable to water in presence of ADH from posterior pituitary. If ADH is present, the filtrate will become further concentrated as water flows out into the salty medulla.
Describe what mismatched pairs do to DNA
cause damage mismatched pairs result from errors during replication or methylation of guanine (methylated guanine pairs with thymine instead of cytosine)
Density (of water)
d=m/v 1g/cm³
hcG: location, class, function
egg/placenta peptide/water-soluble prevents degeneration of the corpus luteum, maintaining pregnancy
Define repression
ego defense mechanism by which information is unconsciously pushed out of conscious awareness.
Describe electron flow in organic reactions
electron dense species (bases or nucleophiles) always attack electron poor species (electrophiles)
What is collective behavior
social processes or "collectives" that do NOT reflect stable social structure but emerge in a spontaneous way Neither normative or deviant Exists when social norms are absent, unclear, or conflict with one another
What would damage to the dominant hemisphere result in (assuming they are right handed)?
would likely result in language difficulties and loss of control of movement to the right side of the body. Damage to non-dominant hemisphere would result in some control of movement to the left side and possible difficulties with spatial reasoning and emotional processing