Anatomy ch. 5 bone remodeling steps
2nd step of bone remodeling
activation phase; the pre-osteoclasts become fused and form multinucleated osteoclasts
5th step of bone remodeling
after the pit is completed, the osteoclasts disappear
4th step of bone remodeling
as the pit is being dug out calcium can be released into the blood for use by the body
1st step of bone remodeling
during the activation phase, the pre-osteoclasts are attracted to the remodeling sites
8th step of bone remodeling
during the formation phase, the pre-osteoblasts mature into osteoblasts at the surface of the burrow pit
3rd step of bone remodeling
during the resorption phase, the osteoclasts dig out a cavity called a resorption pit
6th step of bone remodeling
in the reversal phase, mesenchymal stem cells appear along the burrow or pit
7th step of bone remodeling
the cells along the pit increase in number and become specialized into pre-osteoblasts
9th step of bone remodeling
the osteoblasts busy themselves by releasing osteoid (a soft, nonmineralized bone matrix)
11th step of bone remodeling
the remodeling site (now new bone tissue) remains resting/quiescence until the next bone remodeling cycle begins
10th step of bone remodeling
this phase must be called the formation phase because the new matrix becomes mineralized with calcium and phosphorus thus creating new bone