AP PSYCH 2 cont.
The Synaptic vesicles contain
neurotransmitters. they are fluid filled sacs
Serotonin
a neurotransmitter found in the lower part of the brain that can have either an excitatory or inhibitory effect, depending on the particular synapses being affected.
reuptake
process by which neurotransmitters are taken back into the synaptic vesicles
synaptic knob
rounded areas on the end of the axon terminals
Because molecules of various drugs, if similar enough in shape to the neurotransmitter, can fit into the receptor sites on the receiving neurons just like the neurotransmitters do, drugs can affect what happens in the synapse in two ways
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If acetylcholine receptor sites on the muscle cells are blocked in some way, then the acetylcholine can't get to the site and the muscle will be incapable of contracting-paralyzed in other word. This is what happens when the drug, curare, gets into the nervous system. Indians used for blow darts.
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It is not the neurotransmitter itself that is excitatory or inhibitory, but rather it is the effect of that neurotransmitter that is either excitatory or inhibitory at the receptor sites of a particular synapse
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So, if the original neurotransmitter was excitatory, the effect of the agonist will be to INCREASE that inhibition.
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effect of alcohol is to enhance the effect of GABA. This makes alcohol an agonist for GBA
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chemical substances that mimic or enhance the effects of neurotransmitters on the receptor sites of the next cell, which can result in an increase or decrease in the activity of the receiving cell, depending on what effect of the original neurotransmitter (Excitatory or inhibitory) was going to be.
Agonists
Chemical substances that block or reduce a cell's response to the action of other chemicals or neurotransmitters
Antagonists
GABA is involved in _____ and ____ _____
GABA is involved in sleep and inhibits movement
Endorphins
Inhibitory neural regulators; involved in pain relief. natural pain killers.
Too little dopamine
Parkinson's disease. tremor, muscle rigidity, etc..
When the neuron's action potential occurs, ____ ions are rushing into the axon through openings on the membrane
Sodium
branches at the end of the axon
axon terminals
GABA can help to
calm anxiety. (Drugs and alcohol)
a strong message received by a neuron will
cause the neuron to fire immediately, in a faster fashion.
Antagonists
chemical substances that BLOCK or REDUCE a cell's response to the action of other chemical neurotransmitters.
agonists
chemical substances that mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, INCREASING or DECREASING the activity of that cell.
low levels of serotonin results in
depression
When people take heroin or morphine, their bodies neglect to produce ____
endorphins. Thus, they want more drugs because everything hurts because the are left with no protection against pain at all.
Acetylcholine has an
excitatory effect on the synapse
Acetylochine
excitatory or inhibitory; involved in arrousal, attention, memory, and controls muscle contractions. MAAC
dopamine
excitatory or inhibitory; involved in control of movement and sensations of pleasure
Acetylcholine- neurotransmitter
found at the synapses between neurons and muscle cells. Serves to stimulate the skeletal muscles to contract but actually slows contractions in the heart muscle.
Nervous system's most excitatory neurotransmitter
glutamate
receptor sites
holes in the surface of dendrites or certain cells of the muscles and glands, which are shaped to fit only certain neurotransmitters.
myelin
insulates axons and speeds up transmitting of neural message
When an antagonist drug affects an inhibitory neurotransmitter...chem stubstance released by the end of a nerve fiber (ntransmitter) half of def
it increases the activity of the cell
Glutamate plays an important role in
learning, memory formation, and nervous system development
vesicle means
little blister or fluid-filled sac. latin
Norepinephrine
mainly excitatory; involved in arousal and mood. MA. NO MA
synapse/synaptic gap
microscopic fluid-filled space between the synaptic knob of one cell and the dendrites or surface of the next cell
GABA (neurotransmitter)
most common neurotransmitter producing inhibition in the brain.
neurotransmitters are inside a
neuron
the field of study that deals with the structure of the brain and components of the nervous system
neuroscience
Inside synaptic vesicles are chemicals suspended in fluid, which are molecules of substances called
neurotransmitters
chemical found in synaptic vesicles that, when released, has an effect on the next cell.
neurotransmitters
When the action potential reaches the end of the axon terminals, it causes the release of
neurotransmitters that excite or inhibit the next cell
oligodendrocytes
produce myelin in the central nervous system
Schwann cells
produce myelin in the peripheral nervous system
synaptic vesicles
saclike structures found inside the synaptic knob containing chemicals
Too much dopamine
schizophrenia
Which neurotransmitter is associated with sleep, mood, and appetite?
serotonin
Serotonin is associated with
sleep, appetite, and mood (SAM-serotonin)
excitatory synapse
synapse at which a neurotransmitter causes the receiving cell to fire. Neurotransmitter tells receiving cell to fire. starts pain. turn cells on.
inhibitory synapse
synapse at which a neurotransmitter causes the receiving cell to stop firing. Neurotransmitter tells receiving cell to stop firing. stops pain. turn cells off.
When the action potential, or electrical charge, reaches the synaptic vesicles, the synaptic vesicles release their neurotransmitters into the
synaptic gap
What would happen if the neurons released too much acetylcholine?
the bite of a black widow spider does just that. Its venom stimulates the release of excessive amounts of acetylcholine and causes CONVULSIONS and POSSIBLE DEATH. Black widow spider venom is an agonist for acetylcholine. Acetylcholine is also found in the hippocampus which responsible for forming new memories. Low levels of this causes Alzheimer's disease, the most common type of dementia.
Neurotransmitters ____
transmit a message
all-or-none
when a neuron fires, it fires in an all-or-none fashion. Neurons are either firing at full strength or not firing at all
