ASCP Exam Simulator Missed Questions
Isoenzymes of alkaline phosphatase occur in
Kidney, bone, intestines, liver
Which type of lipoprotein transports the majority of cholesterol to cells for steroid hormone synthesis or cell membrane incorporation
LDL
Which spirochete is a causative agent of human disease and is acquired through contact with the urine of carrier animals
Leptospira interrogans sensu stricto
Which of the following drugs is used primarily for the treatment of manic-depression
Lithium
What are the two polypeptide chains that comprise the LD molecule
M and H
In the evaluation of a positive DAT, all of the following techniques can be used to dissociate the antibodies from the RBCs except
Saline replacement
Which of the following steps must be followed to prepare a platelets concentrate
Whole blood centrifuged at low speed - plasma separates then centrifuged at high speen
How many doses of RhIg should be administer if the calculated amount of fetal whole blood volume in maternal circulation was 28 mL
2 doses
Which of the following is least likely to interfere with the measurement of hemoglobin
Cold agglutinin
Which blood product should be shipped on dry ice
FFP
In essential thrombocythemia, the platelets are usually
Increased in number and functionally abnormal
A patient presents with an elevation of unconjugated bilirubin, normal serum alkaline phosphatase, normal liver enzymes, and no bilirubin in the urine. This combination would suggest
Increased rate of hemolysis
What blood alcohol concentration ha sheen established as the statuary limit for operation of a motor vehicle in US
80 mg/dL
Antibodies directed against granulocyte antigens have been implicated for all of the following except
Acute hemolytic transfusion reactions
What is the composition of the granules associated with basophilic stippling
Aggregates of ribosomes
Which of the following characteristics of hemolytic disease of the fetus and newborn is NOT different for ABO and Rh HDFN
Antibody is IgG
Prominent vacuolation involving the cytoplasm of abnormal lymphoblast-like cells seen in the peritoneal body fluid preparation is a distinctive feature of which disease
Burkitt Lymphoma
Which parasite are hermaphroditic in their adult phase
Clonorchis sinensis
Which of the following hemoglobins is known to migrate with HbS during electrophoresis when an alkaline gel, such as cellulose acetate, is used
D
Which of the following statements are true about anti-H? A. Anti-H does not react with group O cells B. Anti-H reacts more strongly with group A cells C. Anti-H never reacts with group A cells D. Anti-H reacts more strongly with group A2 cells than A1 cells
D. Anti-H reacts more strongly with group A2 cells than A1 cells
What changes in potassium and sodium serum results may occur with diuretic ise
Decrease in both
The number of patients correctly diagnosed for the disease or not having the disease is defined as
Efficiency
Which organism shows a characteristic "test tube brush-like" pattern at 22 degrees C
Erysipelothrix rhusiopathiae
The long, pencil-shaped, multi-celled, thin, and smooth-walled macroconidia is characteristic of
Exserohilum species
Which of the following is used to analyze risk and highlight aspects of a process that should be targeted for improvement
Failure method and effects analysis (FMEA)
Which of these methods measures fetal hemorrhage or D positive cells or both to evaluate fetomaternal hemorrhage
Flow cytometry
All of the following are true about fluorometry are true except
Fluorescence is indirectly proportional to the absolute being measured
Which of the following methods for long-term diabetic monitoring is recommended for patients with sickle cell anemia
Fructosamine
Which of the following is true of genotype screening in pharmagenomics
Genotype got does not take into account drug interaction a which can affect metabolism
Acute phase proteins generally fall into which category
Glycoproteins
Asaccharolytic use of glucose would be indicated by which of the following reactions in OF glucose tubes?
Green in both tubes with a little blue at the of the open tube
Which organism is NOT apart of the HACEK group that is often associated with infective endocarditis
Haemophilus influenzae
Also as the "Right to know" law, which of these OSHA regulations first dealt with specific information related to the contents of chemicals used in the workplace
Hazard Communication 1910.1200
An increase in total bilirubin with a normal conjugated bilirubin is most likely indicative of
Hemolytic disease
The adult worms of which of which parasite resides in the human intestine
Heterophyes heterophyes
When evaluating a patient for a suspected Wilson's disease diagnosis, low values of plasma ceruloplasmin would be expected along with
Increase urine copper
Which of the following organisms is the leading cause of bacterial meningitis in infants, young children, and adults in the US
Streptococcus pneumonia
Contact dermatitis is mediated by
T lymphocytes
What is the parasite that resides in the human intestine
Taenia solium scolex
Which of the following statements is true for specific gravity measured by the urine chemical reagent strip method
The urine chemical reagent strip method is not affected by the presence of x-ray contrast media in the urine specimen
The term pharmacokinetics best describes
What the body does to the drug
All of the following are characteristics of Burkholderia pseudomallei except
Non-motile
Which best describes an A1 individual
A and A1 antigens on RBCs and anti-B antibodies in serum
What marker is most useful for detection of gestational trophoblastic disease
hCG
Which of the following drug examples would be a good candidate for therapeutic drug monitoring
A drug that has a narrow therapeutic window
Which of the following is the most important factor in deterring the immediate outcomes of kidney transplants
ABO compatibility
What is the cause of iron overload in HH
Absorption of excessive amount of iron in the small intestines
When preparing platelet concentrates from whole blood, after the second spin and excess plasma has been expressed from the platelets, what is the next step in platelet preparation
Allow the platelets to rest for 1-2hrs at 20-24C
For which of the following antibodies is the DAT most likely to be negative when testing a newborn for possible HDFN
Anti-A,B
Glycine-HCL/EDTA treatment of red cells can destroy which of the following antigens, allowing for confirmation of a suspected antibody and detecting additional antibodies
Bg and Kell
All of the following factor would cause an increase in ESR except
Blood drawn into sodium citrate anticoagulant
All of the following are characteristics of CRP except
Bonds with factor H to initiate alternate complement pathway
Which of the following statements best describes the mean and median as the relate to a normal "Gaussian" distribution curve
Both are equal
Which probe type is used to detect translocations?
Break-apart probes
8-hydroxyquinoline and Ortho-Creaolphthalein (CPC) reagent is commonly used in the determination of
Calcium
The most immature neutrophil found in normal peripheral blood is
Neutrophil band
Which of the following statements is true regarding lymphocyte cytoplasmic granules
Lymphocytes May contain a few azurophilic granules in the cytoplasm
Which of the following cells is the most common uncleared cell in normal adult bone marrow
Metamyelocyte
All of the following are UA findings associated with nephrotic syndrome EXCEPT
Mild proteinuria
Which of the following best describes the benefits of the RPR or VDRL tests
Monitoring course of treatment
Characteristic of Type I cryoglobulins include which of the following characteristics
Monoclonal IgG, IgA, or IgM
What is the term used to describe inadequate blood supply that decreases availability of oxygen to the myocardium
Myocardial ischemia
What is the primary oxygen-carrying protein found in muscle
Myoglobin
Which of the following is the earliest biochemical market of myocardial infarction
Myoglobin
What type of lymphocyte appears as a large cell with abundant cytoplasm and a few azurophilic granules
NK lymphocytes
Which of the following parasites are considered as atrial ameba
Naegleria fowleri
The property most responsible for the migration proteins is an electrical field is
Net surface charge
What is NOT a method for measuring specific gravity of urine
Osmolality
All of the following test must be performed before calling the species Bacillus anthracis except
Oxidase
Of the following anticonvulsant medications, which one does not rely solely on the liver to metabolize it for excretion
Phenobarbital
What procedures utilizes leukapheresis to collect the buffy coat from whole blood
Photopheresis
A patient has a history of repeated spontaneous abortions. Coagulation studies reveal an elevated APTT, normal PT, normal platelet function, and normal thrombin time. Schistocytes were seen on the PBS. Which test should be performed to determine if the patient has lupus anticoagulant
Platelet neutralization test
Which of the following is NOT an acute phase protein
Protein S
Within a run, one control is above 2+ SD and the other is 2- SD units from the mean. What do the results indicate
R4S rule is violated due to random error
Which absorption technique removes cold (IgM) antibodies, particularly anti-I specificities
Rabbit erythrocyte storms (RESt)
Which of the following terms could be used to describe an analyzer that can test specimens out of sequence
Random access
Which of the following evaluation tools for documenting direct observations is the least subjective
Rating scale with detailed descriptions of traits
What is a typical regimen for long-term maintenance therapy of individual with hereditary hemochromatosis (HH)
Removal of 2-6 units of blood yearly
Acridine orange is used for
Visualization of bacteria in specimens where debris may be present
What is successful molecular identification of MRSA based upon
The detection of S. aureus genes (orfx, nuc, or coa) gene and the mecA gene
When distinguishing megaloblastic from non-megaloblastic macrocyclic anemia, which of the following is a key difference in red blood cell morphology
The presence of round macrocytes in non-megaloblastic anemia
The type of hypersensitivity reaction associated with macrophage activation, cytokine-mediated inflammation is
Type IV Cell mediated hypersensitivity (T-cell dependent)
A tech is working with a small, GNCB that may be Brucella spp., which of the following tests could the tech use to rule out this organism
Urease negative
The ultimate end product of both epinephrine and norepinephrine metabolism is
Vanillylmandellic acid (VMA)