ASCP Exam Simulator Missed Questions

Isoenzymes of alkaline phosphatase occur in

Kidney, bone, intestines, liver

Which type of lipoprotein transports the majority of cholesterol to cells for steroid hormone synthesis or cell membrane incorporation

LDL

Which spirochete is a causative agent of human disease and is acquired through contact with the urine of carrier animals

Leptospira interrogans sensu stricto

Which of the following drugs is used primarily for the treatment of manic-depression

Lithium

What are the two polypeptide chains that comprise the LD molecule

M and H

In the evaluation of a positive DAT, all of the following techniques can be used to dissociate the antibodies from the RBCs except

Saline replacement

Which of the following steps must be followed to prepare a platelets concentrate

Whole blood centrifuged at low speed - plasma separates then centrifuged at high speen

How many doses of RhIg should be administer if the calculated amount of fetal whole blood volume in maternal circulation was 28 mL

2 doses

Which of the following is least likely to interfere with the measurement of hemoglobin

Cold agglutinin

Which blood product should be shipped on dry ice

FFP

In essential thrombocythemia, the platelets are usually

Increased in number and functionally abnormal

A patient presents with an elevation of unconjugated bilirubin, normal serum alkaline phosphatase, normal liver enzymes, and no bilirubin in the urine. This combination would suggest

Increased rate of hemolysis

What blood alcohol concentration ha sheen established as the statuary limit for operation of a motor vehicle in US

80 mg/dL

Antibodies directed against granulocyte antigens have been implicated for all of the following except

Acute hemolytic transfusion reactions

What is the composition of the granules associated with basophilic stippling

Aggregates of ribosomes

Which of the following characteristics of hemolytic disease of the fetus and newborn is NOT different for ABO and Rh HDFN

Antibody is IgG

Prominent vacuolation involving the cytoplasm of abnormal lymphoblast-like cells seen in the peritoneal body fluid preparation is a distinctive feature of which disease

Burkitt Lymphoma

Which parasite are hermaphroditic in their adult phase

Clonorchis sinensis

Which of the following hemoglobins is known to migrate with HbS during electrophoresis when an alkaline gel, such as cellulose acetate, is used

D

Which of the following statements are true about anti-H? A. Anti-H does not react with group O cells B. Anti-H reacts more strongly with group A cells C. Anti-H never reacts with group A cells D. Anti-H reacts more strongly with group A2 cells than A1 cells

D. Anti-H reacts more strongly with group A2 cells than A1 cells

What changes in potassium and sodium serum results may occur with diuretic ise

Decrease in both

The number of patients correctly diagnosed for the disease or not having the disease is defined as

Efficiency

Which organism shows a characteristic "test tube brush-like" pattern at 22 degrees C

Erysipelothrix rhusiopathiae

The long, pencil-shaped, multi-celled, thin, and smooth-walled macroconidia is characteristic of

Exserohilum species

Which of the following is used to analyze risk and highlight aspects of a process that should be targeted for improvement

Failure method and effects analysis (FMEA)

Which of these methods measures fetal hemorrhage or D positive cells or both to evaluate fetomaternal hemorrhage

Flow cytometry

All of the following are true about fluorometry are true except

Fluorescence is indirectly proportional to the absolute being measured

Which of the following methods for long-term diabetic monitoring is recommended for patients with sickle cell anemia

Fructosamine

Which of the following is true of genotype screening in pharmagenomics

Genotype got does not take into account drug interaction a which can affect metabolism

Acute phase proteins generally fall into which category

Glycoproteins

Asaccharolytic use of glucose would be indicated by which of the following reactions in OF glucose tubes?

Green in both tubes with a little blue at the of the open tube

Which organism is NOT apart of the HACEK group that is often associated with infective endocarditis

Haemophilus influenzae

Also as the "Right to know" law, which of these OSHA regulations first dealt with specific information related to the contents of chemicals used in the workplace

Hazard Communication 1910.1200

An increase in total bilirubin with a normal conjugated bilirubin is most likely indicative of

Hemolytic disease

The adult worms of which of which parasite resides in the human intestine

Heterophyes heterophyes

When evaluating a patient for a suspected Wilson's disease diagnosis, low values of plasma ceruloplasmin would be expected along with

Increase urine copper

Which of the following organisms is the leading cause of bacterial meningitis in infants, young children, and adults in the US

Streptococcus pneumonia

Contact dermatitis is mediated by

T lymphocytes

What is the parasite that resides in the human intestine

Taenia solium scolex

Which of the following statements is true for specific gravity measured by the urine chemical reagent strip method

The urine chemical reagent strip method is not affected by the presence of x-ray contrast media in the urine specimen

The term pharmacokinetics best describes

What the body does to the drug

All of the following are characteristics of Burkholderia pseudomallei except

Non-motile

Which best describes an A1 individual

A and A1 antigens on RBCs and anti-B antibodies in serum

What marker is most useful for detection of gestational trophoblastic disease

hCG

Which of the following drug examples would be a good candidate for therapeutic drug monitoring

A drug that has a narrow therapeutic window

Which of the following is the most important factor in deterring the immediate outcomes of kidney transplants

ABO compatibility

What is the cause of iron overload in HH

Absorption of excessive amount of iron in the small intestines

When preparing platelet concentrates from whole blood, after the second spin and excess plasma has been expressed from the platelets, what is the next step in platelet preparation

Allow the platelets to rest for 1-2hrs at 20-24C

For which of the following antibodies is the DAT most likely to be negative when testing a newborn for possible HDFN

Anti-A,B

Glycine-HCL/EDTA treatment of red cells can destroy which of the following antigens, allowing for confirmation of a suspected antibody and detecting additional antibodies

Bg and Kell

All of the following factor would cause an increase in ESR except

Blood drawn into sodium citrate anticoagulant

All of the following are characteristics of CRP except

Bonds with factor H to initiate alternate complement pathway

Which of the following statements best describes the mean and median as the relate to a normal "Gaussian" distribution curve

Both are equal

Which probe type is used to detect translocations?

Break-apart probes

8-hydroxyquinoline and Ortho-Creaolphthalein (CPC) reagent is commonly used in the determination of

Calcium

The most immature neutrophil found in normal peripheral blood is

Neutrophil band

Which of the following statements is true regarding lymphocyte cytoplasmic granules

Lymphocytes May contain a few azurophilic granules in the cytoplasm

Which of the following cells is the most common uncleared cell in normal adult bone marrow

Metamyelocyte

All of the following are UA findings associated with nephrotic syndrome EXCEPT

Mild proteinuria

Which of the following best describes the benefits of the RPR or VDRL tests

Monitoring course of treatment

Characteristic of Type I cryoglobulins include which of the following characteristics

Monoclonal IgG, IgA, or IgM

What is the term used to describe inadequate blood supply that decreases availability of oxygen to the myocardium

Myocardial ischemia

What is the primary oxygen-carrying protein found in muscle

Myoglobin

Which of the following is the earliest biochemical market of myocardial infarction

Myoglobin

What type of lymphocyte appears as a large cell with abundant cytoplasm and a few azurophilic granules

NK lymphocytes

Which of the following parasites are considered as atrial ameba

Naegleria fowleri

The property most responsible for the migration proteins is an electrical field is

Net surface charge

What is NOT a method for measuring specific gravity of urine

Osmolality

All of the following test must be performed before calling the species Bacillus anthracis except

Oxidase

Of the following anticonvulsant medications, which one does not rely solely on the liver to metabolize it for excretion

Phenobarbital

What procedures utilizes leukapheresis to collect the buffy coat from whole blood

Photopheresis

A patient has a history of repeated spontaneous abortions. Coagulation studies reveal an elevated APTT, normal PT, normal platelet function, and normal thrombin time. Schistocytes were seen on the PBS. Which test should be performed to determine if the patient has lupus anticoagulant

Platelet neutralization test

Which of the following is NOT an acute phase protein

Protein S

Within a run, one control is above 2+ SD and the other is 2- SD units from the mean. What do the results indicate

R4S rule is violated due to random error

Which absorption technique removes cold (IgM) antibodies, particularly anti-I specificities

Rabbit erythrocyte storms (RESt)

Which of the following terms could be used to describe an analyzer that can test specimens out of sequence

Random access

Which of the following evaluation tools for documenting direct observations is the least subjective

Rating scale with detailed descriptions of traits

What is a typical regimen for long-term maintenance therapy of individual with hereditary hemochromatosis (HH)

Removal of 2-6 units of blood yearly

Acridine orange is used for

Visualization of bacteria in specimens where debris may be present

What is successful molecular identification of MRSA based upon

The detection of S. aureus genes (orfx, nuc, or coa) gene and the mecA gene

When distinguishing megaloblastic from non-megaloblastic macrocyclic anemia, which of the following is a key difference in red blood cell morphology

The presence of round macrocytes in non-megaloblastic anemia

The type of hypersensitivity reaction associated with macrophage activation, cytokine-mediated inflammation is

Type IV Cell mediated hypersensitivity (T-cell dependent)

A tech is working with a small, GNCB that may be Brucella spp., which of the following tests could the tech use to rule out this organism

Urease negative

The ultimate end product of both epinephrine and norepinephrine metabolism is

Vanillylmandellic acid (VMA)