Bio Chem HW 1
Which type of interaction is commonly disrupted by the presence of detergents?
Hydrophobic interactions
which amino acid side chain can form an intramolecular hydrogen bond that stabilizes the alpha-helix structure?
Serine
.Which interaction is primarily responsible for the formation of protein dimers and higher-order oligomers?
Hydrophobic interactions
Which type of bond is formed during the primary structure formation of proteins
Peptide bond
Which of the following amino acids is most likely to be found in the interior of a globular protein?
Alanine
Which of the following amino acids has a basic side chain and is positively charged at physiological pH?
Arginine
Which of the following amino acids has a side chain capable of forming salt bridges?
Arginine
which amino acid side chain can form hydrogen bonds due to its carboxyl group?
Aspartic Acid
Which amino acid side chain is most likely to be involved in ionic interactions?
Aspartic acid
Which amino acid side chain can form disulfide bonds?
Cysteine
Which of the following amino acids has a thiol group in its side chain?
Cysteine
Which type of bond or interaction is formed between the side chains of cysteine residues in a protein?
Disulfide bond
Which amino acid side chain can participate in hydrogen bonding due to its amide group?
Glutamine
Which amino acid side chain contains a carboxamide group that can form hydrogen bonds?
Glutamine
Which of the following amino acids has a side chain capable of forming hydrogen bonds?
Glutamine
Which amino acid has a side chain that can act as a proton donor or acceptor in enzyme active sites?
Histidine
Which of the following interactions contributes most significantly to the stability of protein secondary structure?
Hydrogen bonds
Which of the following bonds or interactions is most likely to stabilize the core of a globular protein?
Hydrophobic interactions
Which of the following interactions is most sensitive to changes in pH?
Ionic bonds
Which of the following amino acids has a hydrophobic side chain and is often found in the interior of membrane proteins?
Leucine
Which amino acid side chain can form a covalent bond with the peptide backbone in protein cross-linking?
Lysine
Which amino acid side chain can form covalent cross-links in collagen, contributing to its tensile strength?
Lysine
Which amino acid side chain can form ionic bonds with acidic amino acids?
Lysine
Which amino acid side chain is positively charged at physiological pH and can participate in ionic interactions?
Lysine
Which amino acid has a side chain that can undergo oxidation to form sulfoxides and sulfones?
Methionine
Which type of interaction is responsible for the specificity of enzyme-substrate binding?
Non-covalent interactions
Which of the following amino acids has a hydrophobic side chain?
Phenylalanine
Which of the following amino acids has an aromatic side chain that can participate in pi-pi interactions?
Phenylalanine
Which type of non-covalent interaction occurs between aromatic side chains of amino acids?
Pi-Pi interactions
Which level of protein structure is least affected by changes in pH?
Primary structure
Which amino acid side chain can participate in non-covalent interactions due to its cyclic structure?
Proline
Which amino acid is involved in the catalytic triad of serine proteases?
Serine
Which amino acid side chain can form a covalent bond with the enzyme's active site through a nucleophilic attack?
Serine
Which of the following amino acids is most likely to participate in hydrogen bonding?
Serine
Which amino acid can form a covalent bond with a sugar molecule in glycoproteins?
Threonine
.Which amino acid has a side chain that can engage in van der Waals interactions due to its large aromatic ring?
Tryptophan
Which amino acid has a side chain that can participate in both hydrogen bonding and hydrophobic interactions?
Tryptophan
.Which amino acid side chain can participate in hydrogen bonds and has a hydroxyl group?
Tyrosine
Which amino acid is likely to be phosphorylated in signal transduction pathways?
Tyrosine
Which amino acid side chain contains a hydroxyl group and can be involved in phosphorylation?
Tyrosine
Which amino acid side chain is most likely to participate in hydrophobic interactions in the core of a protein?
Valine
Which non-covalent interaction is highly dependent on the distance between interacting molecules?
Van der Waals forces
Which of the following interactions is the weakest?
Van der Waals forces
