Biology 1st Test - Ch 22; 23; 24

In peas, a gene controls flower color such that R = purple and r = white. In an isolated pea patch, there are 36 purple-flowering plants and 64 white-flowering plants. Assuming Hardy-Weinberg equilibrium, what is the value of q for this population?

0.80

In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of allele a is 0.1. What is the frequency of individuals with AA genotype?

0.81

A population of organisms will not evolve if _____.

All individual variation is due only to environmental factors

Which statement about variation is true?

All new alleles are the result of nucleotide variability

(COME BACK TO) The following question(s) are based on information in Hopi E. Hoekstra, Kristen E. Drumm, and Michael W. Nachman, "Ecological Genetics of Adaptive Color Polymorphism in Pocket Mice: Geographic Variation in Selected and Neutral Genes," Evolution 58(6), 2004: 1329-41. Refer to the figure above. In their investigation of natural selection on Mc1r alleles (the gene that determines coat color) in Arizona pocket mice, Hoekstra et al. determined the frequency of the D and d alleles in each population. They also determined the frequency of alleles for two neutral mitochondrial DNA genes (genes that do not affect and are not linked to coat color). Why did the researchers include the mitochondrial DNA genes as part of their experimental design?

Allele change for the neutral mitochondrial genes serves as a control and gives information on any general background genetic difference among these populations.

You sample a population of butterflies and find that 56% are heterozygous at a particular locus. What should be the frequency of the recessive allele in this population?

Allele frequency cannot be determined from this information

Given what we know about evolutionary biology, we expect to find the largest number of endemic species in which of the following geological features, which have existed for at least a few million years?

An isolated ocean island in the tropics

Scientific theories _____.

Are supported by, and make sense of, many observations

Which variable is likely to undergo the largest change in value resulting from a mutation that introduces a new allele into a population at a locus for which all individuals formerly had been fully homozygous?

Average heterozygosity

Anopheles mosquitoes, which carry the malaria parasite, cannot live above elevations of 5900 feet. In addition, oxygen availability decreases with higher altitude. Consider a hypothetical human population that is adapted to life on the slopes of Mt. Kilimanjaro in Tanzania, a country in equatorial Africa. Mt. Kilimanjaro's base is about 2600 feet above sea level and its peak is 19,341 feet above sea level. If the incidence of the sickle-cell allele in the population is plotted against altitude (feet above sea level), which of the following distributions is most likely, assuming little migration of people up or down the mountain?

B

Of the following anatomical structures, which is homologous to the bones in the wing of a bird?

Bones in the flipper of a whale

If x indicates the location of fossils of two closely related species, then fossils of their most-recent common ancestor are most likely to occur in which stratum?

C

During a study session about evolution, one of your fellow students remarks, "The giraffe stretched its neck while reaching for higher leaves; its offspring inherited longer necks as a result." Which statement is most likely to be helpful in correcting this student's misconception?

Characteristics acquired during an organism's life are generally not passed on through genes

The role that humans play in artificial selection is to _____.

Choose which organisms reproduce

Which of these conditions are always true of populations evolving due to natural selection? Condition 1: The population must vary in traits that are heritable. Condition 2: Some heritable traits must increase reproductive success. Condition 3: Individuals pass on most traits that they acquire during their lifetime.

Conditions 1 and 2

Currently, two of the living elephant species (X and Y) are placed in the genus Loxodonta and a third surviving species (Z) is placed in the genus Elephas. Assuming this classification reflects evolutionary relatedness, which of the following is the most accurate phylogenetic tree?

D

Which of the following must exist in a population before natural selection can act upon that population?

Genetic variation among individuals

Structures as different as human arms, bat wings, and dolphin flippers contain many of the same bones, which develop from similar embryonic tissues. These structural similarities are an example of _____.

Homology

Evolutionary trees such as this are properly understood by scientists to be _____.

Hypotheses

If Darwin had been aware of genes and their typical mode of transmission to subsequent generations, with which statement would he most likely have been in agreement?

If natural selection can change gene frequency in a population over generations, given enough time and genetic diversity, then natural selection can cause sufficient genetic change to produce new species from old ones

A farmer uses triazine herbicide to control pigweed in his field. For the first few years, the triazine works well and almost all the pigweed dies; but after several years, the farmer sees more and more pigweed. Which of these explanations best explains what happened?

Triazine-resistant weeds were more likely to survive and reproduce

Which of the following is a fitness trade-off (compromise)?

Turtle shells provide protection but are heavy and burdensome when moving.

Over long periods of time, many cave-dwelling organisms have lost their eyes. Tapeworms have lost their digestive systems. Whales have lost their hind limbs. How can natural selection account for these losses?

Under particular circumstances that persisted for long periods, each of these structures presented greater costs than benefits

Which of the following evidence most strongly supports the common origin of all life on Earth? All organisms _____.

Use essentially the same genetic code

Prior to the work of Lyell and Darwin, the prevailing belief was that Earth is _____.

a few thousand years old, and populations are unchanging

You are maintaining a small population of fruit flies in the laboratory by transferring the flies to a new culture bottle after each generation. After several generations, you notice that the viability of the flies has decreased greatly. Recognizing that small population size is likely to be linked to decreased viability, the best way to reverse this trend is to _____.

cross your flies with flies from another lab

The Dunkers are a religious group that moved from Germany to Pennsylvania in the mid-1700s. They do not marry with members outside their own immediate community. Today, the Dunkers are genetically unique and differ in gene frequencies, at many loci, from all other populations including those in their original homeland. Which of the following likely explains the genetic uniqueness of this population?

founder effect and genetic drift

A proficient engineer can easily design skeletal structures that are more functional than those currently found in the forelimbs of such diverse mammals as horses, whales, and bats. The actual forelimbs of these mammals do not seem to be optimally arranged because _____.

natural selection is generally limited to modifying structures that were present in previous generations and in previous species

When Cuvier considered the fossils found in the vicinity of Paris, he concluded that the extinction of species _____.

occurs, but that there is no evolution

Adult male humans generally have deeper voices than do adult female humans, which is the direct result of higher levels of testosterone causing growth of the larynx. If the fossil records of apes and humans alike show a trend toward decreasing larynx size in adult females and increasing larynx size in adult males, then _____.

sexual dimorphism was evolving over time in these species

Martin Wikelski and L. Michael Romero (Body size, performance and fitness in Galápagos marine iguanas, Integrative and Comparative Biology 43 [2003]:376-86) measured the snout-to-vent (anus) length of Galápagos marine iguanas and observed the percent survival of different-sized animals, all of the same age. The graph shows the log snout-vent length (SVL, a measure of overall body size) plotted against the percent survival of these different size classes for males and females. Examine the figure above. What type of selection for body size appears to be occurring in these marine iguanas?

stabilizing selection

Most Swiss starlings produce four to five eggs in each clutch. Starlings producing fewer or more than this have reduced fitness. Which of the following terms best describes this situation?

stabilizing selection

Whenever diploid populations are in Hardy-Weinberg equilibrium at a particular locus, _____.

the allele's frequency should not change from one generation to the next

Catastrophism was Cuvier's attempt to explain the existence of _____.

the fossil record

Soon after the island of Hawaii rose above the sea surface (somewhat less than one million years ago), the evolution of life on this new island should have been most strongly influenced by _____.

the founder effect

The inability of organisms to evolve anything that could be an advantage reflects _____.

the limits of historical constraints

If x indicates the fossils of two closely related species, neither of which is extinct, then their remains may be found in how many of these strata?

two strata

With what other idea of his time was Cuvier's theory of catastrophism most in conflict?

uniformitarianism

In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of the allele a is 0.3. What is the frequency of individuals that are homozygous for this allele?

0.09

In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of allele a is 0.2. What is the frequency of individuals that are heterozygous for this allele?

0.32

A large population of laboratory animals has been allowed to breed randomly for a number of generations. After several generations, 25% of the animals display a recessive trait (aa), the same percentage as at the beginning of the breeding program. The rest of the animals show the dominant phenotype, with heterozygotes indistinguishable from the homozygous dominants. What is the estimated frequency of allele A in the gene pool?

0.50

A large population of laboratory animals has been allowed to breed randomly for a number of generations. After several generations, 25% of the animals display a recessive trait (aa), the same percentage as at the beginning of the breeding program. The rest of the animals show the dominant phenotype, with heterozygotes indistinguishable from the homozygous dominants. What proportion of the population is probably heterozygous (Aa) for this trait?

0.50

In some jacana species, males take care of the eggs and young, and females compete among themselves for territories that contain one to several males. Female jacanas are significantly larger than males. Which of these statements would you predict to be true of this bird species? 1. Male jacana fitness is primarily limited by ability to take care of eggs and raise young. 2. Female jacana fitness is limited by the number of males in her territory with which a female mates. 3. Variation in reproductive success should be greater in male jacanas than in females. 4. Variation in reproductive success should be greater in female jacanas than in males. 5. Males and females have equal variation in reproductive success.

1, 2, and 4

Given a population that contains genetic variation, what is the correct sequence of the following events under the influence of natural selection? 1. Well-adapted individuals leave more offspring than do poorly adapted individuals. 2. A change occurs in the environment. 3. Genetic frequencies within the population change. 4. Poorly adapted individuals have decreased survivorship.

2 → 4 → 1 → 3

Arrange the following in order from most general to most specific. 1 natural selection 2. microevolution 3. intrasexual selection 4. evolution 5. sexual selection

4, 2, 1, 5, 3

Rank the following one-base point mutations (from most likely to least likely) with respect to their likelihood of affecting the structure of the corresponding polypeptide. 1. insertion mutation deep within an intron 2. substitution mutation at the third position of an exonic codon 3. substitution mutation at the second position of an exonic codon 4. deletion mutation within the first exon of the gene

4, 3, 2, 1

Suppose 64% of a remote mountain village can taste phenylthiocarbamide (PTC) and must, therefore, have at least one copy of the dominant PTC taster allele. If this population conforms to Hardy-Weinberg expectations for this gene, what percentage of the population must be heterozygous for this trait?

48%

Researchers studying a small milkweed population note that some plants produce a toxin and other plants do not. They identify the gene responsible for toxin production. The dominant allele (T) codes for an enzyme that makes the toxin, and the recessive allele (t) codes for a nonfunctional enzyme that cannot produce the toxin. Heterozygotes produce an intermediate amount of toxin. The genotypes of all individuals in the population are determined (see chart) and used to determine the actual allele frequencies in the population. If, on average, 46% of the loci in a species' gene pool are heterozygous, then the average homozygosity of the species should be _____.

54%

Many crustaceans (for example, lobsters, shrimp, and crayfish) use their tails to swim, but crabs have reduced tails that curl under their shells and are not used in swimming. This is an example of _____.

A vestigial trait

Which of the following is the best modern definition of evolution?

Descent with modification

Cotton-topped tamarins are small primates with tufts of long white hair on their heads. While studying these creatures, you notice that males with longer hair get more opportunities to mate and father more offspring. To test the hypothesis that having longer hair is adaptive in these males, you should _____.

Determine if hair length is heritable

A researcher discovered a species of moth that lays its eggs on oak trees. Eggs are laid at two distinct times of the year: early in spring when the oak trees are flowering and in midsummer when flowering is past. Caterpillars from eggs that hatch in spring feed on oak flowers and look like oak flowers. But caterpillars that hatch in summer feed on oak leaves and look like oak twigs. How does the same population of moths produce such different-looking caterpillars on the same trees? To answer this question, the biologist caught many female moths from the same population and collected their eggs. He put at least one egg from each female into eight identical cups. The eggs hatched, and at least two larvae from each female were maintained in one of the four temperature and light conditions listed below. In each of the four environments, one of the caterpillars was fed oak flowers, the other oak leaves. Thus, there were a total of eight treatment groups (4 environments × 2 diets). Refer to the accompanying figure. Which one of the following is NOT a plausible hypothesis to explain the differences in caterpillar appearance observed in this population?

Differences in air pressure, due to differences in elevation, trigger the development of different types of caterpillars

A researcher discovered a species of moth that lays its eggs on oak trees. Eggs are laid at two distinct times of the year: early in spring when the oak trees are flowering and in midsummer when flowering is past. Caterpillars from eggs that hatch in spring feed on oak flowers and look like oak flowers. But caterpillars that hatch in summer feed on oak leaves and look like oak twigs. How does the same population of moths produce such different-looking caterpillars on the same trees? To answer this question, the biologist caught many female moths from the same population and collected their eggs. He put at least one egg from each female into eight identical cups. The eggs hatched, and at least two larvae from each female were maintained in one of the four temperature and light conditions listed below. In each of the four environments, one of the caterpillars was fed oak flowers, the other oak leaves. Thus, there were a total of eight treatment groups (4 environments × 2 diets). Refer to the accompanying figure. In every case, caterpillars that feed on oak flowers look like oak flowers. In every case, caterpillars that were raised on oak leaves looked like twigs. These results support which of the following hypotheses?

Differences in diet trigger the development of different types of caterpillars

Which of the following, if discovered, could refute our current understanding of the pattern of evolution?

Diverse fossils of mammals in Precambrian rock

Mutation is the only evolutionary mechanism that _____.

Does little to change allele frequencies

Which statement about the beak size of finches on the island of Daphne Major during prolonged drought is true?

Each bird's survival was strongly influenced by the depth and strength of its beak as the drought persisted

How many distinct species, both living and extinct, are depicted in this tree?

Eleven

Swine are vulnerable to infection by bird flu virus and human flu virus, which can both be present in an individual pig at the same time. When this occurs, it is possible for genes from bird flu virus and human flu virus to be combined. If the human flu virus contributes a gene for Tamiflu resistance (Tamiflu is an antiviral drug) to the new virus, and if the new virus is introduced to an environment lacking Tamiflu, then what is most likely to occur?

If the Tamiflu-resistance gene involves a cost, it will experience directional selection leading to reduction in its frequency.

The horizontal axis of the cladogram depicted below is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V-Z) represent various common ancestors. Let's say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species. Starting from the wild mustard Brassica oleracea, breeders have created the strains known as Brussels sprouts, broccoli, kale, and cabbage. Therefore, which of the following statements is correct?

In this wild mustard, there is enough heritable variation to permit these different varieties

It has been observed that organisms on islands are different from, but closely related to, similar forms found on the nearest continent. This is taken as evidence that ____.

Island forms are descended from mainland forms

The greatest number of endemic species is expected in environments that are _____.

Isolated and show little ecological diversity

What must be true of any organ described as vestigial?

It must be homologous to some feature in an ancestor

In the mid-1900s, the Soviet geneticist Lysenko believed that his winter wheat plants, exposed to increasingly colder temperatures, would eventually give rise to more cold-tolerant winter wheat. Lysenko's attempts in this regard were most in agreement with the ideas of _____.

Lamarck

Which pair of scientists below would probably have agreed with the process that is depicted by this tree?

Lamarck and Wallace

Fossils of Thrinaxodon, a species that lived during the Triassic period, have been found in both South Africa and Antarctica. Thrinaxodon had a reptile-like skeleton and laid eggs, but small depressions on the front of its skull suggest it had whiskers and, therefore, fur. Thrinaxodon may have been warm-blooded. The fossils of Thrinaxodon are consistent with the hypothesis that _____.

Mammals evolved from a reptilian ancestor

The restriction enzymes of bacteria protect the bacteria from successful attack by bacteriophages, whose genomes can be degraded by the restriction enzymes. The bacterial genomes are not vulnerable to these restriction enzymes because bacterial DNA is methylated. This situation selects for bacteriophages whose genomes are also methylated. As new strains of resistant bacteriophages become more prevalent, this in turn selects for bacteria whose genomes are not methylated and whose restriction enzymes instead degrade methylated DNA. Over the course of evolutionary time, what should occur?

Methylated and nonmethylated strains should be maintained among both bacteria and bacteriophages, with ratios that vary over time.

Genetic variation _____.

Must be present in a population before natural selection can act upon the population

In 1986, a nuclear power accident in Chernobyl, USSR (now Ukraine), led to high radiation levels for miles surrounding the plant. The high levels of radiation caused elevated mutation rates in the surviving organisms, and evolutionary biologists have been studying rodent populations in the Chernobyl area ever since. Based on your understanding of evolutionary mechanisms, which of the following most likely occurred in the rodent populations following the accident?

Mutation led to increased genetic variation

In 1983 a population of dark-eyed junco birds became established on the campus of the University of California, San Diego (UCSD), which is located many miles from the junco's normal habitat in the mixed-coniferous temperate forests in the mountains. Juncos have white outer tail feathers that the males display during aggressive interactions and during courtship displays. Males with more white in their tail are more likely to win aggressive interactions, and females prefer to mate with males with more white in their tails. Females have less white in their tails than do males, and display it less often. (Pamela J. Yeh. 2004. Rapid evolution of a sexually selected trait following population establishment in a novel habitat. Evolution 58[1]:166-74.) The UCSD campus male junco population tails are about 36% white, whereas the tails of males from nearby mountain populations are about 40-45% white. The founding stock of UCSD birds was likely from the nearby mountain populations because some of those birds overwinter on the UCSD campus each year. Population sizes on the UCSD campus have been reasonably large, and there are significant habitat differences between the UCSD campus and the mountain coniferous forests; UCSD campus has a more open environment (making birds more visible) and a lower junco density (decreasing intraspecific competition) than that in the mountain forests. Given this information, which of the following evolutionary mechanisms do you think is most likely responsible for the difference between the UCSD and mountain populations?

Natural Selection

Darwin and Wallace were the first to propose _____.

Natural selection as the mechanism of evolution

For a biologist studying a small fish population in the lab, which Hardy-Weinberg condition is easiest to meet?

No gene flow

For biologists studying a large flatworm population in the lab, which Hardy-Weinberg condition is most difficult to meet?

No mutation

Currently, two extant elephant species (X and Y) are classified in the genus Loxodonta, and a third species (Z) is placed in the genus Elephas. Thus, which statement should be true?

Species X and Y share a greater number of homologies with each other than either does with species Z

Which of Darwin's ideas had the strongest connection to his reading of Malthus's essay on human population growth?

Struggle for existence

Researchers studying a small milkweed population note that some plants produce a toxin and other plants do not. They identify the gene responsible for toxin production. The dominant allele (T) codes for an enzyme that makes the toxin, and the recessive allele (t) codes for a nonfunctional enzyme that cannot produce the toxin. Heterozygotes produce an intermediate amount of toxin. The genotypes of all individuals in the population are determined (see chart) and used to determine the actual allele frequencies in the population. Refer to the figure above. Is this population in Hardy-Weinberg equilibrium?

No; there are more homozygotes than expected

DDT was once considered a "silver bullet" that would permanently eradicate insect pests. Instead, DDT is largely useless against many insects. Which of these would have prevented this evolution of DDT resistance in insect pests?

None of the insect pests would have genetic variations that resulted in DDT resistance

Pseudogenes are _____.

Nonfunctional vestigial genes

Researchers studying a small milkweed population note that some plants produce a toxin and other plants do not. They identify the gene responsible for toxin production. The dominant allele (T) codes for an enzyme that makes the toxin, and the recessive allele (t) codes for a nonfunctional enzyme that cannot produce the toxin. Heterozygotes produce an intermediate amount of toxin. The genotypes of all individuals in the population are determined (see chart) and used to determine the actual allele frequencies in the population. The higher the proportion of loci that are "fixed" in a population, the lower are that population's _____.

Nucleotide variability and average heterozygosity

HIV's genome of RNA includes the code for reverse transcriptase (RT), an enzyme that acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR), an enzyme that acts later in infection by cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR. Every HIV particle contains two RNA molecules. If two genes from one RNA molecule become detached and then, as a unit, get attached to one end of the other RNA molecule within a single HIV particle, which of these is true?

One of the RNA molecules has experienced gene duplication as the result of translocation

Which of the following represents an idea that Darwin learned from the writings of Thomas Malthus?

Populations tend to increase at a faster rate than their food supply normally allows

The horizontal axis represents time (present time is on the far right) and the vertical axis represents morphological change. Logically, which of these should cast the most doubt on the relationships depicted by an evolutionary tree?

Relationships between DNA sequences among the species did not match relationships between skeletal patterns.

In a hypothetical environment, fishes called pike-cichlids are visual predators of large, adult algae-eating fish (in other words, they locate their prey by sight). The population of algae-eaters experiences predatory pressure from pike-cichlids. Which of the following is least likely to result in the algae-eater population in future generations?

Selection for larger female algae-eaters, bearing broods composed of more, and larger, young

Parasitic species tend to have simple morphologies. Which of the following statements best explains this observation?

Simple morphologies convey some advantage in most parasites

A biologist studied a population of squirrels for fifteen years. During that time, the population was never fewer than thirty squirrels and never more than forty-five. Her data showed that over half of the squirrels born did not survive to reproduce, because of both competition for food and predation. In a single generation, 90% of the squirrels that were born lived to reproduce, and the population increased to eighty. Which inference(s) about this most recent surge in the population size might be true?

The amount of available food may have increased and/or the predators that prey upon squirrels may have decreased

A researcher discovered a species of moth that lays its eggs on oak trees. Eggs are laid at two distinct times of the year: early in spring when the oak trees are flowering and in midsummer when flowering is past. Caterpillars from eggs that hatch in spring feed on oak flowers and look like oak flowers. But caterpillars that hatch in summer feed on oak leaves and look like oak twigs. How does the same population of moths produce such different-looking caterpillars on the same trees? To answer this question, the biologist caught many female moths from the same population and collected their eggs. He put at least one egg from each female into eight identical cups. The eggs hatched, and at least two larvae from each female were maintained in one of the four temperature and light conditions listed below. In each of the four environments, one of the caterpillars was fed oak flowers, the other oak leaves. Thus, there were a total of eight treatment groups (4 environments × 2 diets). Refer to the accompanying figure. Recall that eggs from the same female were exposed to each of the eight treatments used. This aspect of the experimental design tested which of the following hypotheses?

The differences are genetic. A female will either produce all flowerlike caterpillars or all twig-like caterpillars

Claytonia virginica is a woodland spring herb with flowers that vary from white to pale pink to bright pink. Slugs prefer to eat pink-flowering over white-flowering plants (due to chemical differences between the two), and plants experiencing severe herbivory are more likely to die. The bees that pollinate this plant also prefer pink to white flowers, so that Claytonia with pink flowers have greater relative fruit set than Claytonia with white flowers. A researcher observes that the percentage of different flower colors remains stable in the study population from year to year. Given no other information, if the researcher removes all slugs from the study population, what do you expect to happen to the distribution of flower colors in the population over time?

The percentage of pink flowers should increase over time

A large population of laboratory animals has been allowed to breed randomly for a number of generations. After several generations, 25% of the animals display a recessive trait (aa), the same percentage as at the beginning of the breeding program. The rest of the animals show the dominant phenotype, with heterozygotes indistinguishable from the homozygous dominants. 27) What is the most reasonable conclusion that can be drawn from the fact that the frequency of the recessive trait (aa) has not changed over time?

The two phenotypes are about equally adaptive under laboratory conditions

Members of two different species possess a similar-looking structure that they use in a similar way to perform about the same function. Which of the following would suggest that the relationship more likely represents homology instead of convergent evolution?

The two species share many proteins in common, and the nucleotide sequences that code for these proteins are almost identical

About thirteen different species of finches inhabit the Galápagos Islands today, all descendants of a common ancestor from the South American mainland that arrived a few million years ago. Genetically, there are four distinct lineages, but the thirteen species are currently classified among three genera. The first lineage to diverge from the ancestral lineage was the warbler finch (genus Certhidea). Next to diverge was the vegetarian finch (genus Camarhynchus), followed by five tree finch species (also in genus Camarhynchus) and six ground finch species (genus Geospiza). If the six ground finch species have evolved most recently, then which of these is the most logical prediction?

Their genomes should be more similar to each other than are the genomes of the five tree finch species

If the bacterium Staphylococcus aureus experiences a cost for maintaining one or more antibiotic-resistance genes, what would happen in environments that lack antibiotics?

These bacteria would be outcompeted and replaced by bacteria that have lost these genes

HIV's genome of RNA includes the code for reverse transcriptase (RT), an enzyme that acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR), an enzyme that acts later in infection by cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR. Which of the following represents the treatment option most likely to avoid the evolution of drug-resistant HIV (assuming no drug interactions or side effects)?

Using moderate doses of NA and two different PIs at the same time for several months

The horizontal axis represents time (present time is on the far right) and the vertical axis represents morphological change. Which of these is the extant (that is, living) species most closely related to species X?

V

Which of the five species, labeled V-Z, is the common ancestor of the fewest number of species?

V

The horizontal axis represents time (present time is on the far right) and the vertical axis represents morphological change. Which species is most closely related to species W?

V is most closely related to species W

Researchers discovered that a new strain of bacteria that cause tuberculosis (M. tuberculosis) taken from a dead patient has a point mutation in the rpoB gene that codes for part of the RNA polymerase enzyme. This mutant form of RNA polymerase does not function as well as the more common form of RNA polymerase. A commonly used antibiotic called rifampin does not affect the mutant rpoB bacteria. A researcher mixes M. tuberculosis with and without the rpoB mutation and adds the bacteria to cell cultures. Half the cell cultures contain only standard nutrients, while the other half of the cell cultures contain rifampin and the standard nutrients. After many cell generations, the researcher finds that _____.

Very few M. tuberculosis in the standard nutrient cell cultures carry the rpoB gene mutation, but almost all of the M. tuberculosis in the cell cultures with rifampin carry the rpoB mutation

Which of the following scientists argued that variation among individuals allows evolution to occur?

Wallace

(COME BACK TO) The following question(s) are based on information in Hopi E. Hoekstra, Kristen E. Drumm, and Michael W. Nachman, "Ecological Genetics of Adaptive Color Polymorphism in Pocket Mice: Geographic Variation in Selected and Neutral Genes," Evolution 58(6), 2004: 1329-41. The figure above shows the distribution of pocket-mouse coat colors in several Arizona populations found either on light-colored granite substrate or on dark volcanic rock (dark substrate). The Melanocortin-1 receptor (Mc1r) alleles, D and d, differ by four amino acids. Mice with DD and Dd genotypes have dark coats, whereas mice with the dd genotype are light colored. What sort of genotype frequencies might you expect to find in the Xmas, Mid, and O'Neill populations?

Xmas-high dd frequency; Mid-high DD frequency, O'Neill-high Dd frequency

Which of the five common ancestors, labeled V-Z, is the common ancestor of the greatest number of species, both living and extinct?

Y

In 1983 a population of dark-eyed junco birds became established on the campus of the University of California, San Diego (UCSD), which is located many miles from the junco's normal habitat in the mixed-coniferous temperate forests in the mountains. Juncos have white outer tail feathers that the males display during aggressive interactions and during courtship displays. Males with more white in their tail are more likely to win aggressive interactions, and females prefer to mate with males with more white in their tails. Females have less white in their tails than do males, and display it less often. (Pamela J. Yeh. 2004. Rapid evolution of a sexually selected trait following population establishment in a novel habitat. Evolution 58[1]:166-74.) Refer to the paragraph on dark-eyed junco birds. The UCSD campus male junco population tails were, on average, 36% white, whereas the tails of males from nearby mountain populations averaged 40-45% white. If this observed trait difference were due to a difference in the original colonizing population, it would most likely be due to _____.

a founder effect

An earthquake decimates a ground-squirrel population, killing 98% of the squirrels. The surviving population happens to have broader stripes, on average, than the initial population. If broadness of stripes is genetically determined, what effect has the ground-squirrel population experienced during the earthquake?

a genetic bottleneck

The horizontal axis of the cladogram depicted below is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V-Z) represent various common ancestors. Let's say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species. The cow Bos primigenius (which is bred for meat and milk) has a smaller brain and larger eyes than closely related wild species of ungulates. These traits most likely arose by _____.

artificial selection, because changes in these traits co-occurred with human selection for high milk output and high muscle content

Martin Wikelski and L. Michael Romero (Body size, performance and fitness in Galápagos marine iguanas, Integrative and Comparative Biology 43 [2003]:376-86) measured the snout-to-vent (anus) length of Galápagos marine iguanas and observed the percent survival of different-sized animals, all of the same age. The graph shows the log snout-vent length (SVL, a measure of overall body size) plotted against the percent survival of these different size classes for males and females. Currently the only predators of Galápagos marine iguanas are Galápagos hawks. Iguana body size is not correlated with risk of hawk predation, although small iguanas can sprint faster than large iguanas. If predators (for example, cats) that preferably catch and eat slower iguanas are introduced to the island, iguana body size is likely to _____ in the absence of other factors; the iguanas would then be under _____ selection.

decrease; directional

Which of the following is the most predictable outcome of increased gene flow between two populations?

decreased genetic difference between the two populations

In a very large population, a quantitative trait has the following distribution pattern. If there is no gene flow, the curve shifts to the left or to the right, and the population size consequently increases over successive generations, which of the following is most likely occurring?

directional selection

In those parts of equatorial Africa where the malaria parasite is most common, the sickle-cell allele constitutes 20% of the β hemoglobin alleles in the human gene pool. In the United States, the parasite that causes malaria is not present, but African-Americans whose ancestors were from equatorial Africa are present. What should be happening to the sickle-cell allele in the United States, and what should be happening to it in equatorial Africa?

directional selection; stabilizing selection

Darwin and Wallace's theory of evolution by natural selection was revolutionary because it _____.

dismissed the idea that species are constant and emphasized the importance of variation and change in populations

A biologist doing a long-term study on a wild spider population observes increased variation in silk thickness. Which of the following could the spider population be experiencing?

disruptive selection

Three-spined stickleback fish (Gasterosteus aculeatus) show substantial heritable variation in gill-raker length related to differences in their diets. Longer gill rakers appear to function better for capturing open-water prey, while shorter gill rakers function better for capturing shallow-water prey. Which of the following types of selection is most likely to be found in a large lake (open water in the middle and shallow water around the sides) with a high density of these fish?

disruptive selection

After the drought of 1977, researchers on the island of Daphne Major hypothesized that medium ground finches that had large, deep beaks, survived better than those with smaller beaks because they could more easily crack and eat the tough Tribulus cistoides fruits. If this hypothesis is correct, what would you expect to observe if a population of these medium ground finches colonizes a nearby island where Tribulus cistoides is the most abundant food for the next 1000 years? Assume that (1) even the survivors of the 1977 drought sometimes had difficulty cracking the tough T. cistoides fruits and would eat other seeds when offered a choice; and (2) food availability is the primary limit on finch fitness on this new island.

evolution of yet larger, deeper beaks over time

Cystic fibrosis is a genetic disorder in homozygous recessives that causes death during the teenage years. If 9 in 10,000 newborn babies have the disease, what are the expected frequencies of the dominant (A1) and recessive (A2) alleles according to the Hardy-Weinberg model?

f(A1) = 0.9700, f(A2) = 0.0300

The restriction enzymes of bacteria protect the bacteria from successful attack by bacteriophages, whose genomes can be degraded by the restriction enzymes. The bacterial genomes are not vulnerable to these restriction enzymes because bacterial DNA is methylated. This situation selects for bacteriophages whose genomes are also methylated. As new strains of resistant bacteriophages become more prevalent, this in turn selects for bacteria whose genomes are not methylated and whose restriction enzymes instead degrade methylated DNA. The outcome of the conflict between bacteria and bacteriophage at any point in time results from _____.

frequency-dependent selection

When imbalances occur in the sex ratio of sexual species that have two sexes (that is, other than a 50:50 ratio), the members of the minority sex often receive a greater proportion of care and resources from parents than do the offspring of the majority sex. This is most clearly an example of _____.

frequency-dependent selection

Over time, the movement of people on Earth has steadily increased. This has altered the course of human evolution by increasing _____.

gene flow

In the formula for determining a population's genotype frequencies, the "2" in the term 2pq is necessary because _____.

heterozygotes can come about in two ways

In the formula for determining a population's genotype frequencies, the "pq" in the term 2pq is necessary because _____.

heterozygotes have two alleles

After the drought of 1977, researchers hypothesized that on the Galápagos island Daphne Major, medium ground finches with large, deep beaks survived better than those with smaller beaks because they could more easily crack and eat the tough Tribulus cistoides fruits. A tourist company sets up reliable feeding stations with a variety of bird seeds (different types and sizes) so that tourists can get a better look at the finches. Which of these events is now most likely to occur to finch beaks on this island?

increased variation in beak size and shape over time

On the Bahamian island of Andros, mosquitofish populations live in various, now-isolated, freshwater ponds that were once united. Currently, some predator-rich ponds have mosquitofish that can swim in short, fast bursts; other predator-poor ponds have mosquitofish that can swim continuously for a long time. When placed together in the same body of water, the two kinds of female mosquitofish exhibit exclusive breeding preferences. If one builds a canal linking a predator-rich pond to a predator-poor pond, then what type(s) of selection should subsequently be most expected among the mosquitofish in the original predator-rich pond, and what type(s) should be most expected among the mosquitofish in the formerly predator-poor pond?

less-intense directional selection; more-intense directional selection