blood

What organ serves as the control center for the regulation of erythropoiesis?

kidney

Through the microscope, you notice a very large leukocyte with a U-shaped nucleus but no granules. What type of leukocyte have you observed?

monocyte

Patient MK's blood-typing chart showed agglutination with the Anti-A, Anti-B and Anti-Rh sera. What is the patient's blood type?

AB+

universal recipient blood type

AB+

People who have the B antigen on the surface of their red blood cells have ________ antibodies in their plasma.

anti-A

White blood cells that have an S-shaped nucleus and large dark-staining granules are the __________.

basophil

Neutrophils are most effective at:

fighting a bacterial infection

plasma

- fluid portion of blood - made of water with diffused proteins, ions, gases, and waste

acceptable donors for type AB+

A+, A-, B+, B-, AB+, AB-, O+, and O-

acceptable donors for type A+

A+, A-, O+, and O-

acceptable donors for type A-

A- and O-

acceptable donors for type AB-

A-, B-, AB-, and O-

what blood type is compatible with B during a transfusion?

O

acceptable donors for type O+

O+ and O-

acceptable donors for type O-

O-

leukocyte

- nucleus has many granules in the cytoplasm - helps attach pathogens in body

thrombocyte

- tiny pieces of a larger cell that plug damaged vessels - stops blood loss

eryhtrocytes

- transport oxygen on hemoglobin - anucleate - red blood cell

What is von Willebrand factor?

a clotting protein important in platelet plug formation

During a transfusion, if incompatible antigens are introduced, antibodies can bind to foreign antigens, causing them to clump together, or:

agglutinate

what solute is a plasma protein?

albumin

People who have both A and B antigens on the surface of their red blood cells have neither ___________ and _________ antibodies in their plasma.

anit-A or anti-B

Like the ABO blood group, the Rh blood group is important in determining blood transfusion compatibility. Which of the following statements is true regarding the Rh blood group?

anti- Rh (D) antibodies are found in Rh- individuals who have been exposed to Rh+ blood

People who have neither A nor B antigens on the surface of their red blood cells have ________________ and ___________ antibodies in their plasma

anti-A and anti-B

People who have the A antigen on the surface of their red blood cells have _________ antibodies in their plasma.

anti-B

What protein is responsible for tagging foreign particles, pathogens, or blood for destruction?

antibodies

ABO blood group is based on what anitgen?

antigens A and B

Nora was exposed to radiation that caused her red bone marrow to make fewer red blood cells. This condition is known as __________

aplastic anemia

what might trigger erythropoiesis?

blood oxygen levels fall below normal

During a tapeworm infection, you would expect to see increased numbers of:

eosinophil

If a patient had a parasitic infection, you would expect an elevated __________ count.

eosinophil

what formed element contains hemoglobin?

erythrocyte

The hematocrit is the percentage of blood composed of______

erythrocytes

formed elements of blood are...

erythrocytes, leukocytes, and platelets

true or false Erythropoiesis operates on a positive feedback loop maintained by erythropoietin.

false

true or false: Type B- agglutinates in anti-B and anti-Rh sera.

false

All leukocytes arise from:

hematopoietic stem cells (HSCs)

Bilirubin comes from the breakdown of:

heme molecules of hemoglobin that lack iron

What organ secretes most of the plasma proteins?

liver

Which type of leukocyte may produce antibodies?

lymophocyte

Platelets are cell fragments formed from:

megakaryocytes

Platelets form from large cells called __________.

megakaryocytes

Which leukocyte becomes a macrophage when it moves into connective tissue?

monocyte

What is the most common type of leukocyte in a healthy adult?

neutrophil

Type O blood has what ______ antigen

none

Jerry is an alcoholic and does not eat enough food. He has been diagnosed with a vitamin deficiency. What blood disorder is the most likely a result of this deficiency?

pernicious anemia

the majority of blood is ________

plasma

what forms the majority of blood?

plasma

When blood is centrifuged, what is found in the buffy coat?

platelets and leukocytes

All red blood cells in an adult originate in the ________

red bone marrow

What do platelets do to aid coagulation?

release chemicals that stimulate clotting

Which organ traps older erythrocytes so they will be removed from circulation?

spleen

what formed element functions in blood clotting?

thrombocyte

what is the function of red blood cells?

transport oxygen and carbon dioxide

true or false: Agglutinogens are only found on the surface of red blood cells.

true

true or false: If the Rh antigen is lacking, the blood is Rh negative.

true

true or false: The most common cause of abnormal hemoglobin is an inherited condition known as sickle-cell anemia

true

true or false: The most common leukocyte is the neutrophil while the least common leukocyte is the basophil.

true

true or false: Thrombin converts fibrinogen into fibrin, a mesh that glues together the platelet plug and helps seal the damaged vessel.

true

true or false: Type O- does not agglutinate in anti-A, anti-B, or anti-Rh sera.

true

How do vascular spasms contribute to the process of hemostasis?

vascular spams limit blood loss

In the beginning of of platelet plug formation, the chemical produced by endothelial cells at the site of injury is called __________.

von Willebrand factor

true or false: Antibodies are responsible for agglutination of blood cells.

true

how much blood does the average adult have?

5 L

what is normal blood pH?

7.40

Type AB blood has ______ antigen

A and B antigen

Type A blood has ______ antigen

A antigen

Type B blood has ______ antigen

B antigen

What antigen is present on the surface of B+ erythrocyte?

B antigen and +Rh antigen

acceptable donors for type B+

B+, B-. O+, and O-

acceptable donors for type B-

B- and O-