Blood Types, Antigens, & Antibodies
Agglutination
-clumping of RBCs & hemolysis due to having both antigens and antibodies in the blood (lock & key)
Rh- means...
-do not have antigen
Where was the Rh antigen first discovered?
-in the blood of the rhesus monkey
Antibodies
-produced by immune system (lymphocytes)(WBCs) -*marks cells to be destroyed* -*keys*
Antigen
-protein on the surface of RBC -have specific shape -surface markers for the cell -*locks*
Which blood type is the universal receiver?
-type AB
Which blood type is the universal donor?
-type O-
Transfusions
-worry only about A, B, & Rh antigens -if incompatible the antigens will cause hemolysis of recipients to RBCs -(you don't want both the lock and the key)
Rh+ means...
-you have the antigen
If neither antigen is on RBCs of type O blood...
-you will have antibodies A & B in plasma -universal donor
If you have antigen B on RBCs of type b blood...
-you will have antibody A in plasma
If you have antigen A on RBCs of type A blood...
-you will have antibody B in plasma
If you have antigen A & B on RBCs of type AB blood...
-you will have neither antibody in plasma -universal acceptor
What two antigen types is blood type based on?
-A & B