Ch 12

1) Lampbrush chromosome a) H1 histone 2) Histone b) Chromosome separation 3) Linker DNA c) Alu sequence 4) CEN region d) Polytene chromosome 5) VNTR e) Oocytes and spermatocytes 6) SINE f) Minisatellites 7) Chromosomal puff g) Lysine and arginine

1) e 2) g 3) a 4) b 5) f 6) c 7) d

2) In E.coli, the genetic material is composed of A) Circular, double-stranded DNA B) Linear, double-stranded DNA C) RNA and protein D) Circular, double-stranded RNA E) Polypeptide chains

A) Circular, double-stranded DNA

3) Eukaryotic chromosomes contain two general domains that relate to the degree of condensation. These two regions are A) Heterochromatin and euchromatin B) Uniform in the genetic information they contain C) Separated by large sketches of repetitive DNA D) Each void of typical protein-coding sequences of DNA E) Void of introns

A) Heterochromatin and euchromatin

6) Chromatin of eukaryotes is organized into repeating interactions with protein octomers called nucleosomes. Nucleosomes are composed of which class of molecules? A) Glycoproteins B) Histones C) Lipids D) H1 histones E) Nonhistone chromosomal proteins

B) Histones

4) In human chromosomes, satellite DNA sequences of about 170 base pairs in length are present in tandem arrays of up to 1 million base pairs. Found mainly in centromere regions, they are called A) Telomeres B) Primers C) Alphoid families D) Euchromatic regions E) Telomere-associated sequences

C) Alphoid families

1) Viral chromosomes exist in a variety of structures and can be made up of the following; A) Protein- or lipid-coding sequences B) DNA only C) DNA or RNA D) RNA only E) DNA, RNA or protein

C) DNA or RNA

7) Supercoiling relies on the enzyme A) Helicase B) DNAse C) Topoisomerase D) DNA polymerase I E) Primase

C) Topoisomerase

5) In addition to highly repetitive and unique DNA sequences, a third category of DNA sequences exist. What is it called and what types of elements are involved? A) Composite DNA, telomeres and heterochromatin B) Dominant DNA, heterochromatin and euchromatin C) Multiple gene family DNA, hemoglobin and 70s RNA D) Moderately repetitive DNA, SINEs, LINEs and VNTR E) Permissive DNA, centromeres and heterochromatin

D) Moderately repetitive DNA, SINEs, LINEs and VNTR

2) In contrast to euchromatin, heterochromatin contains more genes and is earlier replicating. T/ F

F

3) Viral genomes are always either double-stranded DNA or single-stranded RNA. T/ F

F

5) Presence of heterochromatin is characteristic of prokaryotic chromosome. T/ F

F

1) Telomerase is an enzyme involved in the replication of the ends of eukaryotic chromosomes. T/F

T

4) Polytene chromosomes are unique because they are composed of a large number of identical DNA strands. T/ F

T