Ch 18 Blood Worksheet
Hematocrit blood value can indicate
blood doping
breakdown of hemoglobin
- Old RBC's rupture, releasing hemoglobin. - Hemoglobin is ingested by macrophages - Hemoglobin is broken down into a heme and globin - the globin group is broken down into amino acids that are metabolized or used to build more proteins - the heme is broken down into iron and biliverdin - biliverdin is converted to free bilirubin - iron is transported by transferrin in the blood to various tissues such as the liver or spleen for storage or to red bone marrow to make new hemoglobin (by erythropoiesis) - free bilirubin is transported in the blood by albumin and carried to the liver. - liver cells make conjugated bilirubin which is excreted as part of the bile into the small intestine. - intestinal bacteria convert bilirubin into bilirubin derivatives which contribute to the brown color of feces - Some bilirubin derivatives are absorbed in the blood and are excreted from the kidneys into the urine
Choose the correct statement(s) regarding the composition of plasma. Check all that apply.
1) Water represents 92% by weight.2) Albumin is 60% of the total protein portion.3) The most abundant nitrogenous waste is urea. Plasma is a complex mixture of water, proteins, nutrients, electrolytes, nitrogenous wastes, hormones, and gases. By weight, water represents 92%. Protein is the most abundant plasma solute by weight, totaling 6 to 9 g/dL. Albumin represents 60% of the total protein.
Differential WBC
A differential determines the relative amounts of each of the five types of WBC's which is more diagnostically valuable than just the total number of WBC's alone. - agranulocytes are the lymphocytes and monocytes - the granulocytes are the neutrophils eosinophils and basophils. -
Match the type of granulocyte in Column A with the description in Column B.
Basophil: Contain blue or purple cytoplasmic granules Neutrophil: Contain lavender cytoplasmic granules Eosinophil: Contain orange or red cytoplasmic granules
what white blood cell(s) is/are classified as an agranulocyte?
Lymphocyte and Monocyte
what white blood cell(s) is/are classified as a granulocyte?
Neutrophil, Basophil, Eosinophil
Hematocrit is a measurement of the percentage of blood volume composed of which formed element?
RBC's
Which of the following is/are classified as a formed element of blood?
RBC, WBC, and platelets
Blood types A, B, AB, and O form the ______ blood group.
ABO
Your ABO blood type is determined by the presence or absence of ____________ on your RBCs.
ANTIGNES
________ occurs when blood is mismatched during a transfusion.
Agglutination
Antibodies ____________ to antigens and mark them for destruction.
BIND
These antibodies react with ____________ RBC antigens.
foreign
What are the components of the circulatory system?
heart, blood vessels, blood
These complexes ____________ the antigens until immune cells can break them down.
immobilize
After binding, the antigens are ____________ together.
stuck
What determines a persons blood types
the presence of antigens on the RBCs
In addition to the ABO and Rh groups, there are at least 100 other known blood groups, but they rarely cause transfusion reactions.
true
T or F: hemolysis refers to the breakdown of RBCs
true
A hematocrit of ____% would be normal
45% Men: 42%-52% Women: 37%-48%
One method of destruction is called ____________ , in which each antibody binds two or more antigens.
agglutination
Hemoglobin Determination can indicate
anemia
Each antigen will have a different ____________ complex on the surface of the RBC.
carbohydrate
Blood typing can determine
compatibility for blood transfusions
Repetition of this process produces antigen antibody ____________ .
complexes
WBC smallest to greatest
neutrophils lymphocytes monocytes eosinophils basophils
The antibodies related to the ABO blood group are located
on the RBC membranes
Additionally, ____________ will contain antibodies.
plasma
