CH 57 GI Secretion Meds

A 75-year-old client is diagnosed with type 2 diabetes mellitus, hypertension, osteoporosis, and gastric ulcer disease. She is prescribed PPIs. The nurse is aware that long-term (greater than 1 year) administration of PPIs may increase the risk for which problem for this client? Liver cancer Peptic ulcer disease Hip fractures Hypercalcemia

Hip fractures

Which of the following best reflects the rationale for using histamine-2 receptor antagonists for stress ulcer prophylaxis? Reduces the overall acid level, promoting healing and comfort Blocks the overproduction of hydrochloric acid Decreases the acid being regurgitated into the esophagus Protects the stomach lining via acid blockage

Protects the stomach lining via acid blockage

A female client presents to the health care provider's office with increasing stomach acidity. She self-administers calcium antacids. She notes that she seems to be having more issues with stomach acid, so she has been taking the calcium antacids more frequently. The nurse suspects that this may have caused what to occur in this client? Hypocalcemia Rebound acidity Gastric reflux Hyperactive gastric mucosa

Rebound acidity

A 30-year-old nonpregnant patient is prescribed misoprostol. Which of the following should the nurse instruct the patient as part of the teaching plan? Swallow the tablet one hour before eating. Administer the drug one hour before travel. Do not chew, open, or crush the tablet. Use a reliable contraceptive.

Use a reliable contraceptive.

The nursing instructor is teaching students about proper administration of sucralfate. According to the instructor, sucralfate should be administered: with meals. with an antacid. an hour before meals. immediately after each meal.

an hour before meals.

prostaglandin

any one of numerous tissue hormones that have local effects on various systems and organs of the body, including vasoconstriction, vasodilation, increased or decreased GI activity, and increased or decreased pancreatic enzyme release.

proton pump inhibitor

drug that blocks the H+, K+-ATPase enzyme system on the secretory surface of the gastric parietal cells, thus interfering with the final step of acid production and lowering acid levels in the stomach

histamine-2 (H2) antagonist

drug that blocks the H2 receptor sites; used to decreased acid production in the stomach (H2 sites are stimulated to cause the release of acid from the parietal cells in response to gastrin or parasympathetic stimulation)

gastrointestinal protectant

drug that coats any injured area in the stomach to prevent further injury from acid or pepsin

digestive enzymes

enzymes produced in the gastrointestinal tract to break down foods into usable nutrients

peptic ulcer

erosion of the lining of the stomach or duodenum; results from imbalance b/w acid produced and the mucous protection of the GI lining or possibly from infection by H. pylori bacteria.

antacids

group of inorganic chemicals that neutralize stomach acid

acid rebound

reflex response of the stomach to lower-than-normal acid levels; when acid levels are lowered through the use of antacids, gastrin production and secretion are increased to return the stomach to its normal acidity