Ch.14
The host defenses include_____ immunity which is present at birth, and ________immunity which is acquired over time and specific in its action.
innate and adaptive
What are small protein molecules that are produced by certain leukocytes and tissue cells in response to viral infection called?
interferons
Which of the following is NOT a main function of inflammation?
lead to allergic reaction
Filtration of lymphatic fluid occurs primarily in the
lymph nodes
A system of vessels and organs that serve as sites for the development of immune cells, immune surveillance, and immune reactions is the __ system.
lymphatic
Lymph is transported through a system of Blank______ vessels.
lymphatic
The spleen, thymus, lymph nodes, and GALT are all components of the system.
lymphatic
The second most predominant type of leukocyte in circulation is the
lymphocyte
The group of leukocytes that includes B cells, NK cells, and T cells, are known generally as Blank______.
lymphocytes
Which cell type is NOT one of the major phagocytic cells of the immune system?
lymphocytes
A large, phagocytic white blood cell, derived from a monocyte, that leaves the circulation and plays a role in specific immune reactions while residing in tissues is called a(n) Blank______.
macrophage
Monocytes may leave the circulation and differentiate into
macrophages
Organs lined with mucous membranes contain a discrete population of lymphocytes and other white blood cells known as Blank______ to respond to the constant influx of microbes through theses portals of entry.
malt
A large agranulocyte that differentiates into macrophages and dendritic cells is a(n) .
monocyte
Which large agranulocytes are the precursors to macrophages and dendritic cells?
monocyte
All organs and tissues contain a network of fibers and macrophages called the Blank______ system.
mononuclear phagocyte
The body compartments that participate in the immune system, after the formation of immune cells, are the Blank______.
mononuclear phagocyte system, bloodstream, lymphatic system, and extracellular fluid
Leukocytes that circulate in the blood in high numbers but spend most of their life in the tissues serving as phagocytes are
neutrophils
Leukocytes that circulate in the blood in high numbers but spend most of their life in the tissues serving as phagocytes are .
neutrophils
Which type of leukocytes have conspicuous, lobed nuclei and fine, pale lavender granules?
neutrophils
White blood cells carry a variety of _______ _______receptors that allow them to detect foreign substances.
pattern and recognition
In addition to phagocytosis and initiation of inflammation, white blood cells have the capacity to discover foreign substances using surface receptors known as Blank______.
pattern recognition receptors
The system that functions in the immune system by providing a passageway within and between tissues is the mononuclear ___________system.
phagocyte
Body compartments that participate in immune function are the mononuclear _____system, fluid, the _____, and the lymphatic system .
phagocyte, extracellular, and bloodstream
What is the main role of neutrophils?
phagocytosis
Inborn, nonspecific defenses include ____ ____ ____
physical, chemical, and genetic
The fluid portion of the blood that carries proteins, nutrients, and clotting factors, and in which blood cells are normally suspended, is
plasma
The clear fluid from blood that contains clotting proteins is_______ , whereas the clear fluid from clotted blood that does not contain clotting proteins is ._______
plasma and serum
Readily distinguished from cells by their small size, __ are formed elements in the blood that are involved in blood clotting and hemostasis.
platelets
formed elements in the blood that are involved in hemostasis and blood clotting are
platelets
What is/are the role(s) of the lymph nodes?
provision of immune cells filitration of lymphatic fluid provding sites for immunne reactions
Which of the following are functions of the spleen?
remove worn out rbs from circulation filtration of pathogens from the blood
The host inflammatory response is a component of the Blank______ line of defense.
second
what is the clear fluid from clotted blood often used in immune testing and therapy
serum
An organ that is similar in function to a lymph node except it filters blood instead of lymph is the
spleen
what the funtion of the thymus gland
the maturation of t cells
The main important role of the mononuclear phagocyte system in immune function is:
the provision of a passageway within and between tissues.
Secondary lymphoid organs, where encounters with microbes and immune responses occur, include the Blank______.
thymus gland and bone marrow
The main fluid in plasma is
water
If a sample contains erythrocytes, leukocytes, and platelets suspended in plasma, the sample is called Blank______.
whole blood
The liquid connective tissue that consists of cells such as erythrocytes and leukocytes, along with platelets suspended in plasma, is
whole blood
The complement system is composed of at least Blank______ proteins.
30
Which of the following is NOT a nonspecific host defense?
Antibody production
A lymphocyte that matures in the bone marrow and is involved in the production of antibodies for humoral immunity is called a
B
When viewing leukocytes under a light microscope, staining with a hematologic stain produces some cells with granular structures in the cytoplasm. Leukocytes that do not have visible cytoplasmic granules under these conditions are called
agranulocyte
White blood cells with an unlobed, rounded nucleus and the absence of tiny inclusions in their cytoplasm are referred to as
agranulocytes
Plasma contains globulin proteins, which include
antibodies
Histamine-releasing granulocytic leukocytes include mast cells and
basophil
Which motile granulocytes function in inflammatory events and allergies by releasing histamine?
basophils
Which of the following are granulocytes?
basophils, eosinophils, and neutrophils
Hematopoiesis is the process by which all cells are formed in bone marrow.
blood
Granulocytes that are distinguished in a stain preparation by their larger, orange to red granules and bilobed nucleus are Blank______.
eosinophils
red blood cells are called
erythrocytes
White blood cells that make up 1% to 3% of the total WBC count, and that contain granules with lysozyme, peroxidase, and other digestive enzymes, are
esosinophils
Which of the following is not found in blood plasma?
formed elements
Which of the following are characteristics of B lymphocytes?
free movement between lymphoid organs and connective tissue maturation in the bone marrow production of antibodies when activated
The associated lymphoid tissue that includes the appendix and Peyer's patches is
galt
Mucosal-associated lymphoid tissue (MALT) responds to microbes entering through the Blank______ systems.
gastrointestinal respiratory urinary tract
All three interferons bind to cell surface receptors and induce a change in expression in the target cell, resulting in the production of antiviral proteins.
gene
Neutrophils, eosinophils and basophils all belong to which type of leukocytes?
granulocytes
What is the process by which blood cells are formed in bone marrow?
hematapoiesis
The study of all features of the body's second and third lines of defense is
immunology
A reaction to any traumatic event in the tissues that attempts to restore homeostasis is
inflammation
Substances that are released by cells in an injured area that act on endothelial cells and smooth muscle cells are called Blank______
chemical mediators ctyokines
The circulatory system consists of the organs and tissues of both the Blank______ and Blank______.
circulatory system proper and lymphatic system
A system of blood proteins that enhances the ability of antibodies and phagocytic cells to clear pathogens from an organism is the system.
complement
A chemical substance produced by blood cells and tissue cells that regulates development, inflammation, and immunity is a(n)
cytokine
The main functions of the inflammatory response are:
destroy microbes and block their further invasion mobilization and attraction of immune components to the sites of infection of trauma repair of damaged tissues