Chem 224 Ch. 19
Show how you would use direct alkylation to synthesize the following compounds.
19-16 a
Show how you would use direct alkylation to synthesize the following compounds
19-16 b
Show how you would use direct alkylation to synthesize the following compounds
19-16 c
Give the products expected from the following reactions
19-17 a
Give the products expected from the following reactions
19-17 b
Give the products expected from the following reactions
19-17 c
Give the products expected when the following tertiary amines are treated with a peroxyacid and heated
19-21 a
Give the products expected when the following tertiary amines are treated with a peroxyacid and heated
19-21 b
Give the products expected when the following tertiary amines are treated with a peroxyacid and heated
19-21 c
Give the products expected when the following tertiary amines are treated with a peroxyacid and heated
19-21 d
with sodium nitrile in dilute HCl
19-23 a
with sodium nitrile in dilute HCl
19-23 b
with sodium nitrile in dilute HCl
19-23 c
with sodium nitrile in dilute HCl
19-23 d
Convert aniline to following compounds
19-25 a
Convert aniline to following compounds
19-25 b
Convert aniline to following compounds
19-25 c
Convert aniline to following compounds
19-25 d
Convert aniline to following compounds
19-25 e
Convert aniline to following compounds
19-25 f
Convert aniline to following compounds
19-25 g
Convert aniline to following compounds
19-25 h
Show how to synthesize the following amines from the indicated starting materials by reductive amination.
19-26 a-b
Show how to synthesize the following amines from the indicated starting materials by reductive amination.
19-26 c-d
Show how to synthesize the following amines from the indicated starting materials by reductive amination
19-26 e-f
Which of the amines listed next is resolved into enantiomers? In each case, explain why interconversion of the enantiomers does or does not take place
19-4 b
Which of the amines listed next is resolved into enantiomers? In each case, explain why interconversion of the enantiomers does or does not take place
19-4 c
Which of the amines listed next is resolved into enantiomers? In each case, explain why interconversion of the enantiomers does or does not take place
19-4 d
Which of the amines listed next is resolved into enantiomers? In each case, explain why interconversion of the enantiomers does or does not take place
19-4 e
19-37
Complete the following proposed acid-base reactions, and predict whether the reactants or products are favored
19-32
For each compound, (1) classify the nitrogen-containing functional groups. (2) provide an acceptable name.
19-35
In each pair of compounds, select the stronger base, and explain your choice
19-38 a-g
Predict the products of the following reactions:
19-38 b
Predict the products of the following reactions:
19-38 c
Predict the products of the following reactions:
19-38 i-k
Predict the products of the following reactions:
19-39 a-f
Predict the products of the following reactions:
19-39 g-j
Predict the products of the following reactions:
19-46
Propose mechanisms for the following reactions.
19-33
Rank the amines in each set in order of increasing basicity
19-44
Synthesize Novocaine from benzene and any other reagents of four carbons or fewer.
19-45
Synthesize from benzene
19-43
The following drugs are synthesized using the methods in this chapter and in previous chapters. Devise a synthesis for each, starting with any compounds containing no more than six carbon atoms
19-47 a
The two most general amine syntheses are the reductive amination of carbonyl compounds and the reduction of amides. Show how these techniques can be used to accomplish the following syntheses.
19-47 b
The two most general amine syntheses are the reductive amination of carbonyl compounds and the reduction of amides. Show how these techniques can be used to accomplish the following syntheses.
19-42 a
Using any necessary reagents, show how you would accomplish the following syntheses.
19-42 b
Using any necessary reagents, show how you would accomplish the following syntheses.
19-42 g
Using any necessary reagents, show how you would accomplish the following syntheses.
19-36
Which of the following compounds are capable of being resolved into enantiomers?
19-34
Within each structure, rank the indicated nitrogens by increasing basicity
19-3
a
Which of the amines listed next is resolved into enantiomers? In each case, explain why interconversion of the enantiomers does or does not take place
a
19-6
c
19-10
d
19-12
e
19-20a
exhaustive methylation
19-20b
exhaustive methylation
19-20c
exhaustive methylation
19-20d
exhaustive methylation
19-20e
exhaustive methylation
19-20f
exhaustive methylation
19-14 a
f
19-15
g
19-27
i
19-29
j
19-30
k
19-31
l
19-40
the following compounds, using any necessary reagents.
