Exercise 32 GINGER MOUTHRINSE TABLET

Physical Flaws

1. Capping 2. Splitting 3. Mottling 4. Picking 5. Sticking 6. Chipping 7. Crumbling 8. Lamination

The menstruum for the extraction of the active ingredient

95% alcohol

Category

Anti-emetic/ Topical Drug

What is lamination?

Both sides nawala.

Upon putting the tablet in water, the solution produced must be _____.

Clear

Diluent

Dibasic Calcium Phosphate

It contains the active ingredient that is very potent.

Dried ginger

Molded tablets are usually made of the _____ and the _____.

Drug; diluent

Colorant

FDC green

The mixture of 95% alcohol and the dried ginger is macerated for 24 hours. Why?

For complete extraction.

Aqueous solutions frequently containing antiseptics, antibiotics, and/ or aesthetics used for treating the pharnyx and nasopharynx by forcing air from the lungs through the gargle that is held in the throat. It is subsequently expectorated.

Gargles

The active ingredient

Ginger Extract

Official Title

Ginger Mouthrinse Tablet (non-official)

_______ are used in putting the wet mass in the cavity mold as it is transparent allowing one to see if the mold is completely filled.

Glass plate

Appearance

Green tablets

Hardness or Resistance to Friability

Hard, not friable

Cavity mold (must or must not?) completely dried to ensure proper compression.

MUST

What is picking?

May nattering powdered material.

What is chipping?

May portion na nadurog.

Flavorant (2 answers)

Menthol and Peppermint Oil

Small, usually cylindrical, folded or compressed tablets containing small amounts of usually potent drugs.

Molded tablets or tablet triturates

Aqueous solutions often in concentrated form that are used by swishing the liquid in the oral cavity. It can be therapeutic to reduce plaque, gingivitis, dental caries, and stomatitis or cosmetic to reduce bad breath through the use of antimicrobial and/ or flavouring agents.

Mouthwashes

Synonyms

None

What is capping?

One side ay nawala.

Uses

Oral hygiene, Local antiseptic

Texture

Smooth

Disintegrant

Sodium Starch Glycolate

Do not use steel spatula. WHY? Why use plastic spatula instead?

Steel spatula affects the texture. Plastic spatula are more flexible

Packaging Req't

Store in tight containers, in places of low humidity and protected from extreme temperatures.

Preservative and the flavorant

Thymol

Label

Use only as directed. Do not swallow

Container

Wide-mouth amber bottle with cotton plug

Are colorants dependent of the flavour of the preparation?

YES

Are mouthwashes also used as gargles? Can it be used as is or diluted with water?

Yes, mouthwashes are also used as gargles. It can be used as is or diluted with water.

The mold must be _______ before use because different bases will have different densities.

calibrated

Tablet triturates' bases are rapidly soluble and they do not contain ______ or _____ that slow their rate of dissolution. A combination of _____ and ____ is usually the diluent.

lubricant; coating; sucrose; lactose;

The powder mix is _____ so that it will adhere while being pressed in the mold.

moistened

A moistened blend of the drug and the diluent is forced into a _____. The formed mass is then extruded and allowed to dry. The usual base used is lactose and sucrose but drugs that react with sugar require special bases such as _______.

mold; dibasic calcium phosphate

The Ginger extract contains ____ substances that are responsible for _____ property.

phenolic; antiseptic

Since tablet triturates must be readily and completely soluble in water, only a minimal amount of ______ is applied during their manufacture.

pressure

It must be properly compressed to ______

prevent crumbling

Sweetener

saccharin sodium

Many gargles must be diluted with ______ (prior or after?) to use.

water; prior