Exercise 32 GINGER MOUTHRINSE TABLET
Physical Flaws
1. Capping 2. Splitting 3. Mottling 4. Picking 5. Sticking 6. Chipping 7. Crumbling 8. Lamination
The menstruum for the extraction of the active ingredient
95% alcohol
Category
Anti-emetic/ Topical Drug
What is lamination?
Both sides nawala.
Upon putting the tablet in water, the solution produced must be _____.
Clear
Diluent
Dibasic Calcium Phosphate
It contains the active ingredient that is very potent.
Dried ginger
Molded tablets are usually made of the _____ and the _____.
Drug; diluent
Colorant
FDC green
The mixture of 95% alcohol and the dried ginger is macerated for 24 hours. Why?
For complete extraction.
Aqueous solutions frequently containing antiseptics, antibiotics, and/ or aesthetics used for treating the pharnyx and nasopharynx by forcing air from the lungs through the gargle that is held in the throat. It is subsequently expectorated.
Gargles
The active ingredient
Ginger Extract
Official Title
Ginger Mouthrinse Tablet (non-official)
_______ are used in putting the wet mass in the cavity mold as it is transparent allowing one to see if the mold is completely filled.
Glass plate
Appearance
Green tablets
Hardness or Resistance to Friability
Hard, not friable
Cavity mold (must or must not?) completely dried to ensure proper compression.
MUST
What is picking?
May nattering powdered material.
What is chipping?
May portion na nadurog.
Flavorant (2 answers)
Menthol and Peppermint Oil
Small, usually cylindrical, folded or compressed tablets containing small amounts of usually potent drugs.
Molded tablets or tablet triturates
Aqueous solutions often in concentrated form that are used by swishing the liquid in the oral cavity. It can be therapeutic to reduce plaque, gingivitis, dental caries, and stomatitis or cosmetic to reduce bad breath through the use of antimicrobial and/ or flavouring agents.
Mouthwashes
Synonyms
None
What is capping?
One side ay nawala.
Uses
Oral hygiene, Local antiseptic
Texture
Smooth
Disintegrant
Sodium Starch Glycolate
Do not use steel spatula. WHY? Why use plastic spatula instead?
Steel spatula affects the texture. Plastic spatula are more flexible
Packaging Req't
Store in tight containers, in places of low humidity and protected from extreme temperatures.
Preservative and the flavorant
Thymol
Label
Use only as directed. Do not swallow
Container
Wide-mouth amber bottle with cotton plug
Are colorants dependent of the flavour of the preparation?
YES
Are mouthwashes also used as gargles? Can it be used as is or diluted with water?
Yes, mouthwashes are also used as gargles. It can be used as is or diluted with water.
The mold must be _______ before use because different bases will have different densities.
calibrated
Tablet triturates' bases are rapidly soluble and they do not contain ______ or _____ that slow their rate of dissolution. A combination of _____ and ____ is usually the diluent.
lubricant; coating; sucrose; lactose;
The powder mix is _____ so that it will adhere while being pressed in the mold.
moistened
A moistened blend of the drug and the diluent is forced into a _____. The formed mass is then extruded and allowed to dry. The usual base used is lactose and sucrose but drugs that react with sugar require special bases such as _______.
mold; dibasic calcium phosphate
The Ginger extract contains ____ substances that are responsible for _____ property.
phenolic; antiseptic
Since tablet triturates must be readily and completely soluble in water, only a minimal amount of ______ is applied during their manufacture.
pressure
It must be properly compressed to ______
prevent crumbling
Sweetener
saccharin sodium
Many gargles must be diluted with ______ (prior or after?) to use.
water; prior
