hematology exam 1

What component of the erythrocyte is most responsible for its cytoskeleton and cellular integrity?

Cytoskeletal protein

If the lysosomal membrane ruptures, what is the consequence to the cell?

Damages internal cell structures.

Proper specimen collection and patient satisfaction are components of:

quality assurance.

Protein synthesis occurs in what part of a cell?

Ribosomes

What cellular component "directs traffic" for smooth functioning?

Golgi apparatus

a 15 guage needle is thicker than a 23gauge needle

true

hematology is the study of

blood cells

low white blood cell count

leukopenia

After birth, where does hematopoiesis predominantly occur?

Bone marrow

What cellular structures appear as granules with Wright stain?

Lysosomes

What is the Z-Score for Lizzy?

-0.909

What is the Z-Score for Bryan?

0.256

A patient's white blood cells (WBCs) are counted on an automated cell counter 10 times. The mean white count is 8000/mL, and the standard deviation (SD) is 300. What is the coefficient of variation (CV)?

3.8%

In what stage of the cell cycle does DNA replication occur?

s

A test that is positive in all patients who have the disease but also in some who do not have the disease is:

sensitive.

The control values for both controls for the prothrombin test were ranging between the mean and ±1 SD for the first 19 days of use. Starting on day 20, the values for both were consistently between +1 and +2 SDs. This is an example of a:

shift.

The precision limits of a method are defined by:

the SD.

a red tube should be collected for a test that requires serum

true

needle sticks are the most common cause of laboratory accidents

true

when identifying a patient before a phlebotomy, you should have the patient state their name and DOB

true

when performing a phlebotomy, the tourniquet should be removed before removing the needle

true

the morphology of blood cells is important to evaluate

when a profiling instrument result is abnormal

Where are surface markers that help in cell identification found?

Cell membrane

What cellular component is responsible for energy production and metabolic processes?

Mitochondria

The nucleolus of a cell is composed of:

RNA

Which of the MLT students listed have abnormal hematocrits, if any?

john

Which is true regarding reference ranges?

Are ranges of values for an analyte in normal healthy people

order of draw

Blood Cultures (yellow) / Sodium Citrate (light blue) / Serum (red or tiger strip) / Heparin (green) / EDTA (lavendar) / Glucose (gray)

Which morphologic characteristic is representative of apoptosis?

Cell shrinkage

The tubing that brings the lyse reagent to the hemoglobin cuvette on an automated cell counter is pinched and not delivering any reagent. All hemoglobin values are greater than 20 g/dL. This represents what type of error?

Constant systematic

How does the genetically active portion of the nuclear chromatin look when stained with Wright stain?

Diffuse, uncondensed and pale blue

type of tube/tst

Green top Heparin Purple (lavender) top EDTA Blue top 3.2% Sodium citrate Red top No anticoagulant Blood Cultures SPS Grey top Sodium fluoride

The following hemoglobin results, reported in g/dL, are obtained on a hospitalized patient on 3 consecutive days: Day 1Day 2Day 3 14.311.514.4 The SD for this hemoglobin method was calculated in Question 18. A delta check was obtained on day 2. Controls were run as appropriate each day and were all within limits for this procedure.What is the most probable reason for the day 2 result when compared with those for days 1 and 3?

It may represent an error in patient identification.

Erythropoietin is a growth factor affecting erythroid progenitors and is produced by what organ?

Kidney

A laboratory gets numerous complaints regarding the length of time it takes hematology results to get to the emergency department. What would be an appropriate response?

Make this a quality assurance project.

What cellular component of the erythrocyte is its control center?

Nucleus

upon centrifugation of a blood specimen, the layer between the red blood cells and plasma is called the

buffy coat

One of two controls that have been evaluated over the last 28 days gives a result on day 29 between 2 and 3 SDs of the mean; the other control is within 2 SDs of its mean. What is the correct procedure to follow?

Rerun the control and, if acceptable, continue with patients.

Which would most likely be associated with the situation described in Question 11?

Starting a new lot number of thromboplastin reagent

If the cytoplasm of a cell is very basophilic or dark blue when stained with Wright stain, it contains:

large number of ribosomes.

The antinuclear antibody (ANA) test is positive in almost all people who have systemic lupus erythematosus (SLE). It is also positive in some patients who do not have SLE. The antideoxyribonucleic acid (anti-DNA) test is positive only in people with SLE but not in all who do. Which of the following is true?

The ANA test is a good screening test, and anti-DNA test is a good confirmatory test.

A clinical laboratory scientist performs 30 replicate hemoglobin determinations on a single blood sample. When statistics are used to determine the precision of the method, the mean is 13.8 g/dL and 1 SD is 0.1 g/dL. This means that 95.5% of the results on this specimen lie:

between 13.6 and 14.0 g/dL.

A purchased hemoglobin standard is used to adjust a hemoglobinometer. This standard is being used as a:

calibrator

A laboratory comparing its results to those of other laboratories on the same specimen is an example of:

external quality assessment.

the primary function of plts is to

facilitate blood clotting

blood donor centers typically use 23 gauge needles to collect 450 mls of blood

false

blood specimens should be labeled when they arrive in the laboratory and not at the patient bedside

false

The best way to prevent errors in the laboratory is to:

hire professionals with integrity.

Lysosomes are found in the cytoplasm of many cells and contain:

hydrolytic enzymes.

A patient specimen is analyzed on an instrument known to be in control from previous assays performed on a calibrated instrument and gives a hemoglobin result of 13.2 g/dL. Two hours later it is evaluated on another instrument that is being evaluated for purchase by the laboratory. The result is 11.8 g/dL. This result, when compared with the first, is:

inaccurate

Students in an MLT class have their blood collected to determine the class' normal range for Hematocrit. The Hematocrit (HCT) is the percent volume of Whole Blood that is occupied by Red Blood Cells (RBCs). It is a common test for anemia and is included on all CBCs (Complete Blood Cell Counts). The unit of measurement for the HCT is per cent (%). Skylar 43.0 Caroline 41.0 Lizzy 35.0 Caliyah 45.0 Bryan 40.0 Kristin 39.0 Rob 41.0 Leonard 39.0 Tony 38.0 Lorena 35.0 John 29.0 Erika 42.0 Calculate the following values from this data: (2 pt each)

mean= 38.9 mediam=39.5 mode=35, 39, 41 range=16 SD=4.29 CV=11

who is ultimately responsible for determining the specimen integrity before analysis

medical lab professional

A cell that is actively synthesizing protein has:

more nucleoli.

hematocrit is also called

packed red cell volume

What does the CV calculated in Question 2 describe about the white cell counts?

precision

which of the following can be evaluated only through the microscopic examination of stained blood film

presence or absence of cytoplasmic inclusions