Henrietta Lacks
Stanley Gartler discovered there was no contamination of HeLa cells in any of the 18 most commonly used cell cultures
false
The Lackses trusted the doctor's at Johns Hopkis
false
The Tuskegee institute became involved in the mass production of HeLa cells to use in the syphilis study.
false
The term "informed consent" first appeared in court documents in 1989
false
George Gey was diagnosed with liver cancer.
false Pancreatic
What reason does Deborah give for not wanting Skloot to type out Henrietta's records word-for-word?
family privacy???
What obstacle almost kept Deborah from going to see her mother's cells?
her son was caught by the police
What did HeLa cells allow scientists to do for the first time?
perform experiments that would have been impossible with a living human
How was Gartler able to link contamination of cell lines to HeLa cells?
the presence of glucose-6-phosphate dehydrogenase-A
How are different types of cancer cells categorized?
based on the cells they start from
George Gey's cancer cells were cultured to become the GeGe cell line
false
Why did Henrietta end up being raised by her grandfather?
Her father took her there after her mother died in childbirth
What stage of cancer was Henrietta at when she was diagnosed
1
What STD did Henrietta contract while receiving radiation treatments?
Acute gonorrhea
How old was Henrietta when she had her first kid with Day?
14
How old was Lawrence when Henrietta died?
16
What was Clover's population in 1998?
198
How was Cootie related to Henrietta?
1st cousin
What percentage of women initially diagnosed with carcinoma in situ later developed invasive carcinoma?
62%
Give three descriptors to demonstrate why it would be easy to believe the Marvel super villain, Hela, Goddess of Death, was based on Henrietta Lacks.
???
What causes the confrontation between Deborah and Skloot?
???
Why do you think Deborah tells Skloot that she "just witnessed a miracle?"
???
How does Deborah respond after Gary's prayer?
????
What did Henrietta's first doctor assume the source of the lump on Henrietta's cervix was?
A sore from syphilis
All of the following happened when the family started to bury Henrietta's body except
An earthquake
When was she born?
August 1, 1920
Who were the common ancestors of the White and Black Lackses? Choose all that apply.
Benjamin lacks and albert lacks
What important misunderstanding about HeLa does Lengauer clarify for Deborah?
Deborah didn't know that her mother's cells were mixed up with cancer cells.
What made Day change his mind and allow the autopsy to occur?
Doctor's told him it would possibly help his children
What advice did Pattillo give Skloot about dealing with Deborah?
Don't be clinical Don't talk down to her Don't be aggressive DO be compassionate
Who was Lillian
Hela's youngest sister
According to Laure Aurealian, George Gey never actually met Henrietta Lacks.
False
Cervical cancer cells normally grow from erythrocyte cells.
False
The hela cells Mary cultured all died?
False
The pap smear did not improve the survival rate of women diagnosed with cancer
False
In Baltimore county, what day is Henrietta Lacks Day
February 1
How did Bobette find out about HeLa
From Gardenia's Brother in law
How did Rogers discover Henrietta's real name?
From Walter Nelson-Rees
Who developed the Pap Smear?
George Papanicolauo
How are Gladys and Gary related to Deborah?
Gladys is Deborah's aunt and Gary is Deborah's cousin.
Cootie thinks Henrietta's cancer could have come from all of the following EXCEPT
Having multiple STDs
What does Zakariyya blame on Henrietta's cancer cells?
He blames the cells for him being the way that he is. He thinks that they made him "mean"
What is Gary's spiritual explanation for why Henrietta's cells lived on after her death?
He explained that Henrietta was an angel sent by God to the world to help
What does Cootie think about the reason the HeLa cells were used to develop a polio vaccine?
He had polio and Henrietta wanted to take care of him when she was alive, but couldnt
Explain how Davon's heroic actions saved Deborah's life.
He saved her by keeping her awake and not letting her become unconscious
What motivated Michael Rogers to find the Lacks family?
He thought the contamination problem would make a good story
What motivated Pattilo to organize the HeLa Cancer Control Syposium?
He wanted to honor her by holding a symposium in her name
All of the following facts about George Gey's life support the assertion that he never personally profited from the development of HeLa Except
He was sued and lost everything by the Lacks
Why did Franklin Salisbury Jr. contact Deborah?
He was the president of the National Foundation for Cancer Research. He wanted to hold a conference in Henrietta's honor and he wanted to Deborah the story
What was Cootie's real name
Hector Henry
How was Day related to Henrietta? Answer all that apply.
Husband and first cousin
HeLa cells were useful for the study of viruses because they reproduced slow enough to watch the process in real time.
false
Explain the Hayflick limit.
It essentially means that cells can only divide a certain amount of times before the telomeres get so short that they can't divide.
What does Howard Jones' findings about Henrietta's medical records suggest about her cancer?
It had grown at a terrifying rate
All of the following is true of the Supreme Court of California's decision regarding the Moore lawsuit EXCEPT
It was Moore's duty to dispose of his waste or it became the property of the hospital or lab
Why did David Lacks take Henrietta to the public wards at Johns Hopkins instead of a closer hospital?
It was the only major hospital for miles that treated black patients.
What did Howard Jones note about Henrietta's lump? Select all that apply
It was unlike any he had seen Shiny and purple like grape jello bled at the slightest touch
Which of the following is not associated with the "town" of Clover?
Its in Northern Virginia
How did Deborah discover the truth about Keenan Kester Cofield?
Johns Hopkins?
What was Henrietta Lacks' birth name?
Loretta Pleasant
What string of events in 2009 suggest that if Skloot had not begun researching Henrietta's story a decade earlier, it may have been lost forever?
Lots of the family was dying and she wouldn't be able to get enough info.
Who discovered radium and its ability to kill cancer cells?
Marie and Pierre Curie
Where did the name HeLa come from?
Mary labeled all sample tubes with the first two letters of the patient's first and last name
When did George Gey die?
November 8 1970
When did Henrietta Lacks die?
October 4 1951
How long did Henrietta wait between first telling her girlfriends that "something didn't feel right" and going to the doctor?
Over a year
Henrietta Lacks' name became public knowledge after her family sued Johns Hopkins for taking her cells without them knowing
false
All of the following were used as test subjects for Southam's EXCEPT
People with Polio
Why did Deborah choose not to request a copy of her mother's medical records?
She was afraid what she might find and how it would affect her (Deborah).
How was invasive carcinoma treated?
Radium
Where was she born?
Roanoke, VA
Why was Deborah unable to attend the National Foundation for Cancer Research's Henrietta Lacks conference in New York?
She was unable to attend because her son was going on trial and Sept 11 happened and she had a stroke???
What specific things did Deborah ask Skloot to promise she would do?
She asked her to clarify that her mum's name was Henrietta and that she had five siblings.
What gift does Deborah give Zakariyya?
She gave him blankets and the picture of her mother's cells.
What did Howard Jones find "interesting" about Henrietta's medical history?
She had a term baby and 6-week check-up at the hospital but there was no mention of any abnormality of the cervix.
What does Pattillo tell Skloot about Elsie Lacks?
She had epilepsy and that she died age 15
Why wasn't Skloot excited about meeting Zakariyya?
She had heard that he was one of the angriest and most upset of the family about the whole situation
What can you infer about Elsie's treatment based on the description Skloot gives of the photograph of her?
She looked like she was mistreated because of the discoloration, bruises, and swollen skin.
What did Cootie say as Henrietta's body passed by
Sweet Jesus, let the poor woman rest. She's had enough
The lawsuit that set a legal precedent for patenting biological "products" such as cell lines was
The case of Ananda Mohan Chakrabarty
Explain the contribution that HeLa has made to research on the HIV virus and the AIDS epidemic.
The experiments performed with hela cells allowed scientists to figure out how the virus infected cells. It also helped them learn how to stop it.
Give two reasons you can tell that Elsie's photograph and autopsy are deeply troubling to Deborah?
The news was hard to believe. She was gritting her teeth and she didn't want to accept it.
Johns Hopkins built his hospital to serve the poor, but never intended for blacks and other minorities to receive free services.
false
What is the lacks position on suing over the use of HeLa?
There weren't really any laws governing the cells so they can't really sue. There wasn't enough money to start a lawsuit/ hire a lawyer.???
How did Deborah's death change the lives of her brothers?
They cared more about the science of Hela cells. Zakarayya also changed bc he learned about keeping his inner peace and he spent more time with the fam.
Why are HeLa cells able to live beyond the Hayflick limit?
They have an active version of telomerase during cell division. This prevents the incremental shortening of telomeres which causes aging and eventually death. This circumvents the hay flick limit.
Why did Deborah and Skloot travel to Crownsville?
They wanted to see Hela cells and they wanted to know how Elsie died.
According to Henrietta's cousin Cliff, what is "beautiful" about the idea of "slaveowning white Lackses being buried under their black kin?
They're spending eternity in the same place
Why did Ted Slavin start Essential Biologicals?
To allow people with valuable blood to profit from the research done
How did doctors justify using patients in public hospital wards as medical research subjects without obtaining their consent or offering them financial compensation?
To compensate for being treated for free
Why did researchers want DNA samples from Henrietta's family?
To test for Genetic markers to positively identify HeLa cells
Where does Skloot realize she needs to go after watching the BBC documentary and HeLa?
To visit he la's cousins in Clover
Cervical carcinomas are either invasive or noninvasive (TorF)
True
Dr. Telinde believed carcinoma in situ was an early stage of invasive carcinoma
True
Henrietta's doctor failed to tell her that the cancer treatments would leave her infertile.
True
The first time Rebecca spoke with Day he told her to let his old lady cells talk to her and leave him alone.
True
The pap smear allows for detection of precancerous cells
True
Gey sent Henrietta's cells to all of the following places except
Tuskegee
What was the biggest problem faint cell cultures?
bacteria and other microorganisms could contaminate the cultures
Explain how HPV causes cervical cancer.
When infected with HPV, the body generally prevents the body from doing serious harm. However, the virus can survive and eventually convert some of the normal cells of the cervix into cancerous cells.
What is a basic rule about biology with regards to cells?
a normal cell can only divide a finite number of times before dying
After witnessing the amount o physical and emotional anguish that Deborah is in, Gary begins to preach and lay hands on Deborah. a. What burdens does he ask to be lifted from Deborah? b. Where does he ask the burden to be placed?
a) The burdens of the cells, and just everything that came along with it. b) Onto miss rebecca
As Henrietta's cancer progressed, tumors could be found every where except her
brain
Somatic cell fusion happens when one cell eats and digest another one.
false
According to State Attorney General Louis Lefkowitz, what do people have an "inalienable" right to?
determine what shall be done with his or her own body
A second sample of cells taken from Henrietta survived in culture just like the first despite her body being contaminated with toxins normally removed in urine.
false
What is informed consent?
full disclosure of facts regarding procedures
How did prison change joe?
he became muslim and less angry
What does Zakariyya believe about his birth?
he believed his birth was a miracle
What was Chester Southam concerned that HeLa cells might do?
infect the people working with them
Why did Henrietta's doctors need to ask for permission from her family to remove tissue sample after death?
it was illegal to do so w/o consent on a corpse
Explain the significance of the gift that Skloot delivered to Deborah at their first meeting?
it was the first time she was given a picture of her mother's cells
Which of Henrietta's Children did Ethel beat the most
joe
Deborah did all of the following to Cheetah because he was abusive EXCEPT
kill him
All of the following are effects of radium EXCEPT
kills bacteria
How did Henrietta tell Margaret and Sadie she was feeling towards the end of her radiation treatments?
like the blackness was spreading inside of her
What was Henrietta's final request?
make sure her children were taken care of
Why were the hospital records from the 1950s and earlier disposed of?
most papers were contaminated
What crime did Joe commit?
murder
What obstacle kept Deborah from realizing her dream of returning to school?
not enough money, poor health?
An immortal cell line is capable of all of the following EXCEPT
prolonging the life of a human being
What did Lillian "convert" to?
puerto rican
How did Deborah react after reading about her mother's death?
she basically lost it
All of the following are true of Henrietta's decline according to Sadie EXCEPT
she became bitter
How did Bobette respond to Deborah;s pregnancy?
she cried
What information about her mother was Deborah unwilling to share with Skloot?
she didn't want to share her mother's medical records so that her mum would have privacy
Why did doctors stop giving Henrietta blood transfusions?
she had to make up her deficit
What did Mary, Gey's assistant realize when she saw Henrietta's painted toenails?
she was a real person
What did Cofield do when he realized that the Lacks family had blocked his access to their family records?
started a lawsuit against the family
How did Skloot finance the research for her book?
student loans/ credit cards
What unique qualities did HeLa cells have that allowed it to contaminate cultures without researchers being aware? Choose all that apply
they could travel through the ventilation system they could travel on unwashed hands and testubes they could float on dust particles
All of the following are characteristics of HeLa cells made them ideal for use in the polio vaccine>
they dont need a glass surface to grow on they lack anchorage dependency they are more susceptible to the virus than any cell ever cultured before
Why specifically did the Jewish doctors at the Jewish Chronic Disease Hospital object to Southam's cancer study? Select all that apply
they knew of what the Nazi's had done to Jewish prisoners He wanted it done without consent They knew about the Nuremberg trials
HeLa Cells were like normal cells in all of the following ways EXCEPT
they obey cell checkpoints
Why did Zakariyya decide to participate in research studies at Johns Hopkins?
to get a place to stay and to get money
What was the purpose of the Nuremberg code?
to govern all human experimentation worldwide
Why did the Lacks family think the doctors were taking their blood
to test for the cancer gene
Henry Harris and John Watkins discovered internal signals that regulated genes of cells in 1965 by using cell fusion.
true
Howard Jones realized that Henrietta Lacks had been misdiagnosed on her type of cancer when he reviewed her medical records.
true
In outer space, HeLa cells grew more powerful and divided faster
true
It was first and incorrectly reported that the HeLa cell line came from Helen Lane and the cells were cultured after she had died.
true
Neutralization test is used to determine a vaccine's efficacy by mixing blood serum from newly vaccinated children's w/live polio virus and cells in culture.
true
Scientist fused human and animal cells to study what genes do and how they work.
true
Sonny Lacks believed his mother's cells will be used to help other's because she was always and taking care of others when she was alive.
true
The American Type Culture Collection was created to create pure, uncontaminated cell cultures
true
Viruses reproduce by injecting bits of there genetic material int a living cell and reprogramming that cell to produce the virus.
true
What was the official cause of Henrietta's death?
uremia
Why did Deborah decide to go back to school?
wanted to learn more about the science of hela cells
What is benevolent deception?
when doctor's withheld fundamental information from their patients
