immunology( basic concepts)
How many doses of the Hepatitis B vaccine (5µg HBsAg in 0.5mL intramuscular) are required to reach a protective level of antibody?
3
Match the stage of an adaptive (acquired) immune response with the description: Proliferation of cells with matching receptors
Activation phase
Which of the following types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells?
B cell
Which of the following types of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?
B cell
Humoral immunity is mediated by antibodies from____ and is involved in the elimination of____ pathogens. Cell mediated immunity is mediated by____ and is involved in the elimination of____ pathogens
B lymphocytes; Extracellular; T lymphocytes; Intracellular
Which of the following is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells?
Cluster of differentiation 4 (CD4+)
Cluster of differentiation 8 (CD8+)
Cluster of differentiation 8 (CD8+)
Which of the following is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?
Cluster of differentiation 8 (CD8+)
Match the stage of an adaptive (acquired) immune response with the description: Recognition of antigen
Cognitive phase
T cells are made in the____ and complete their differentiation in the____
D. Bone marrow; Thymus
Match the stage of an adaptive (acquired) immune response with the description: Eventual elimination of antigen
Effector phase
What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?
Effector phase
In a resting lymphocyte, B cells and T cells can be distinguished from each other via a simple blood smear
False
Match the following innate immune system cell types with their function: Natural killer cells
Lysis of some virally infected cells
Which of the following types of antigen presenting cells (APCs) is specialized for degradation and presentation of particulate antigens to T cells?
Macrophage
Match the following innate immune system cell types with their function: Eosinophils
Passive immunity
Match the following innate immune system cell types with their function: Neutrophils
Phagocytosis and bacteriocidal mechanisms
Match the following innate immune system cell types with their function: Macrophages
Phagocytosis and bacteriocidal mechanisms, antigen presentation
Match the following innate immune system cell types with their function: Tissue mast cells
Phagocytosis and bacteriocidal mechanisms, antigen presentation
Which of the following produce large amounts of antibodies (Igs) and differentiate upon stimulation from CD4+ cells?
Plasma cells (activated B cells)
Antigen presenting cells (APCs) include macrophages and dendritic cells, which are found in lymphoid tissues and the____. These are critical in the uptake and presentation of antigen to T cells
Skin
Which of the following is NOT a major feature (characteristic) of the adaptive immune system?
Speed