immunology( basic concepts)

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How many doses of the Hepatitis B vaccine (5µg HBsAg in 0.5mL intramuscular) are required to reach a protective level of antibody?

3

Match the stage of an adaptive (acquired) immune response with the description: Proliferation of cells with matching receptors

Activation phase

Which of the following types of antigen presenting cells (APCs) has immunoglobulin that functions as a receptor, then the antigen is internalized, degraded, and presented to T cells?

B cell

Which of the following types of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?

B cell

Humoral immunity is mediated by antibodies from____ and is involved in the elimination of____ pathogens. Cell mediated immunity is mediated by____ and is involved in the elimination of____ pathogens

B lymphocytes; Extracellular; T lymphocytes; Intracellular

Which of the following is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells?

Cluster of differentiation 4 (CD4+)

Cluster of differentiation 8 (CD8+)

Cluster of differentiation 8 (CD8+)

Which of the following is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?

Cluster of differentiation 8 (CD8+)

Match the stage of an adaptive (acquired) immune response with the description: Recognition of antigen

Cognitive phase

T cells are made in the____ and complete their differentiation in the____

D. Bone marrow; Thymus

Match the stage of an adaptive (acquired) immune response with the description: Eventual elimination of antigen

Effector phase

What stage of an adaptive immune response involves secretion of antibody from a large plasma cell with extensive endoplasmic reticulum?

Effector phase

In a resting lymphocyte, B cells and T cells can be distinguished from each other via a simple blood smear

False

Match the following innate immune system cell types with their function: Natural killer cells

Lysis of some virally infected cells

Which of the following types of antigen presenting cells (APCs) is specialized for degradation and presentation of particulate antigens to T cells?

Macrophage

Match the following innate immune system cell types with their function: Eosinophils

Passive immunity

Match the following innate immune system cell types with their function: Neutrophils

Phagocytosis and bacteriocidal mechanisms

Match the following innate immune system cell types with their function: Macrophages

Phagocytosis and bacteriocidal mechanisms, antigen presentation

Match the following innate immune system cell types with their function: Tissue mast cells

Phagocytosis and bacteriocidal mechanisms, antigen presentation

Which of the following produce large amounts of antibodies (Igs) and differentiate upon stimulation from CD4+ cells?

Plasma cells (activated B cells)

Antigen presenting cells (APCs) include macrophages and dendritic cells, which are found in lymphoid tissues and the____. These are critical in the uptake and presentation of antigen to T cells

Skin

Which of the following is NOT a major feature (characteristic) of the adaptive immune system?

Speed


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