LG 1 - Metabolism: Rapid, Short, Intermediate & long acting insulins

A diabetic patient is waiting to undergo a gastrectomy that will take place in 8hrs. The patients A1C's were at 7%, and fasting BG levels were at 180 mg / dL. The patient needs to lower their blood glucose levels before surgery, but cannot be on any insulin that has a duration longer than 6 hours. You know the nurse made the correct choice when she gives the patient: A) Lispro B) Regular C) NPH D) Glargine

A) Lispro Lispro is the only insulin that has a duration lasting up to 6hrs Lispro duration: 3 - 6hrs Regular insulin duration: 6 - 10hrs NPH duration: 16 - 24hrs Glargine duration: 18 - 24hrs

What is an example of a long acting insulin?

Glargine

What type insulin has an onset of 1 - 2hrs and a peak of 6 - 14 hrs? What is an example of this?

Intermediate acting insulin - NPH

What is an example of a rapid acting insulin?

Lispro (Humalog)

What type of insulin has an onset of 70min and no peak? What is an example of this?

Long acting insulin - e.g. Glargine

What is an example of an intermediate acting insulin?

NPH

What is the peak, onset, and duration for NPH?

Onset: 1 - 2hrs Peak: 6 - 14hrs Duration: 16 - 24hrs

What is the onset, peak, and duration of Lispro?

Onset: 15 - 30min Peak: 30min - 2.5 hr Duration: 3hr - 6 hr

What is the onset, peak, and duration of rapid acting insulins?

Onset: 15min - 30min Peak: 30min - 2.5hr Duration: 3-6hr Example: Lispro

What is the peak, onset, and duration of intermediate acting insulin? Example?

Onset: 1hr - 2hrs Peak: 6hrs - 14hr Duration: 16hrs - 24 hrs Example: NPH

What is the peak, onset, and duration of regular insulin?

Onset: 30min - 1hr Peak: 1hr - 5hr Duration: 6hr - 10hr

What is the peak, onset, and duration of short acting insulin? Example

Onset: 30min - 1hr Peak: 1hr -5hrs Duration: 6hrs - 10hrs Example: Regular

What is the onset, peak and duration for glargine?

Onset: 70min Peak: none Duration: 18 - 24 hrs

What is the peak, onset, and duration for long acting insulin? Example?

Peak: 70min Onset: none Duration: 18 - 24hrs Example: Glargine

What are four types of insulin? What are examples of each?

Rapid acting - Lispro Short acting - Regular Intermediate acting - NPH Long acting - Glargine

What is an example of a short acting insulin?

Regular insulin

What type of insulin has an onset of 30min - 1hrs and a peak of 1 - 5hrs? What is an example of this?

Short acting insulin - e.g. Regular

A patient is told by their doctor they should have their breakfast prior to their insulin peaking. The insulin this patient is prescribed will peak around 1-5 hrs after injection. What type of insulin in this patient taking? What is an example of this type of insulin?

Type: Short acting insulin Example: Regular Regular insulin- Onset: 30min - 1hr Peak: 1 - 5 hrs Duration: 6 - 10 hrs