MODULE 3 PRACTICE SET COMPILATION
136
A bottle of mouthwash cost P96.00. At what price must it be sold to yield a gross profit of 40% on the selling price? 186 160 130 148 136
7.5
A child weighing 25 lbs is to receive 4 mg of phenytoin per kg of body weight daily as an anticonvulsant. How many milliliters of pediatric phenytoin suspension containing 30 mg per 5 mL should the child receive? 5.5 7.5 1.5 6.5 3.5
210
A drug company uses the following formula to make 100 capsules Ephedrine sulfate 35 g Amaranth 1.25 g Lactose 225 g What is the weight in grams of Ephedrine sulfate needed to prepare 1.5 kg of the the formula? 210 120 225 233 150
Steven-Johnson's syndrome
A drug-induced hypersensitivity reaction caused by sulfonamides: Parkinson's disease Hypertension Steven-Johnson's syndrome Contact dermatitis
12
A patient has been instructed to take 15 mL of alumina and magnesium oral suspension every other hour for four doses daily. How many days will two 12-fluidounce bottles of the suspension last? 12 17 13 10 15
44,688
A pharmacist receives a bill of goods amounting to P48,000.00, less 5% discount for quantity buying and a 2% cash discount for paying the invoice within 10 days. What is the net amount of the bill? 44,640 44,688 4,800 3,360 33,600
25 mEq
A potassium supplement tablet contains 2.5 g of potassium bicarbonate (MW of KHCO3 = 100). How many milliequivalents of potassium are supplied by the tablet? 20 mEq 35 mEq 15 mEq 25 mEq 30 mEq
essential information is missing
A prescription should be refused when: there is no available delivery service patient is terribly sick it is not signed by the pharmacist essential information is missing
violative Rx
A prescription where the generic name is not written: impossible Rx yellow DDB Rx erroneous Rx violative Rx
potential toxicity
A primary disadvantage of ethylene glycol as a solvent in an oral preparation is its: very limited solubility high viscosity potential toxicity lack of solvent action
decreased effectiveness of the drug
A smoker was prescribed with Diazepam. What would likely happen if he continuously smokes while on drug therapy? enhanced effect of the drug no effectr delayed elimination decreased effectiveness of the drug
Boric Acid
A solution of Physostigmine salicylate which has lost potency should not be dispensed. To prevent this from occurring, what should be added in small amount? Sodium chloride Sodium hydroxide Sodium carbonate Boric acid
1:1250; 1:5000; 1:1000
A tetracycline syrup is preserved with 0.08% (w/v) of methylparaben, 0.02% (w/v) of propylparaben and 0.10% (w/v) of sodium metabisulfite. Express these concentrations as ratio strength 1:1250; 1:5000; 1:1000 1:1000; 13245; 1:0002 1:8000; 1:2000; 1:1000 1:0001; 1:1234; 1:14567 1:1000; 1:2500; 1:5000
160,000
A vitamin capsule contains 6.25 µg of Vitamin B12. How many capsules can be prepared from 1 g of Vitamin B12? 32,000 16,000 320 32 160,000
active alcohol drinkers
Acetaminophen should be used with caution in patients who are: active alcohol drinkers sensitive to GI disturbances caused by salicylates prone to bleeding disorders all of the above
decreased effectiveness of the antifungal agent
Administration of ketoconazole to a patient who is currently taking Ranitidine would likely result in: decreased effectiveness of the antifungal agent enhanced activity of antifungal agent decreased activity of the histamine H2 receptor antagonist increased activity of the antihistamine
adverse drug event
Any drug reaction which does not necessarily have a causal relationship with the treatment is called an: adverse drug event side effects adverse drug reaction therapeutic incompatibility
all of the above
Auxiliary and cautionary labels should be utilized for the purposes of: all of the above warning against concomitant use of certain drugs or foods informing of storage requirements ensuring proper usage
322.35
Calculate the weight in grams of two pints of a syrup, if its specific gravity if 0.975. 970.26 670.05 498.10 899.45 922.35
eutectic combination
Camphor, menthol, acetophenetidine, phenol will form: chemical incompatibility adverse drug reaction eutectic combination physical incompatibility
Type A
Cardiotoxicity caused by Doxorubicin is classified as what type of ADR? Type C Type B Type A Type D
alternative
Complementary list is a list of _____ drugs when there is no response to the core essential list. alternative substitute supplementary additional
preparation of the medicine
Compounding is concerned with: preparation and distribution of drugs order for medicine preparation of medicine supply of a medicine
0.50 mL
Digoxin injection is available in a concentration of 0.1 mg per mL. How many milliliters of the injection will provide a dose of 50 microgram? 0.50 mL 1.0 mL 5.0 mL 50.0 mL 10.0 mL
0.50 mL
Digoxin injection is available in a concentration of 0.1 mg per mL. How many milliliters of the injection will provide a dose of 50 microgram? 1.0 mL 5.0 mL 0.50 mL 50.0 mL 10.0 mL
pharmacokinetic interactions
Drug-drug interactions that occur when one drug alters the absorption, distribution, metabolism and excretion of the other drug: pharmacodynamic interactions adverse drug events pharmacokinetic interactions pharmacologic interactions
1:10,000
Express 0.01% as a ratio strength 1:1,000 1:10 1:100,000 1:10,000 1:100
0.025
Express 250 mcg/mL Warfarin sodium as percentage (w/v). 0.025 0.0001 0.10 0.25 0.0025
0.0005%
Express 5 ppm of iron in water in percentage strength. 0.05% 5% 0.05% 0.5% 0.0005%
type A
Extensive sedation caused by decreased clearance of a usual dose of a benzodiazepine is an example of what type of ADR? type E type B type D type A
Hyperthyroidism
Factors that tend to reduce stomach contraction and gastric emptying rate, except: consumption of meals high in fat depression patient lying on left side hyperthyroidism
physical incompatibility
Failure to mix or dissolve when two or more ingredients are combined may be termed as: adverse reactions physical incompatibility drug precipitation complexation
1.180
Five pints of HCl weigh 2.79 kg. Calculate its specific gravity 1.810 0.810 3.180 2.180 3.850
signa
For the guidance of the patient, the prescription needs inscription subsciption superscription signa
461.5 g
From the following formula, calculate the quantity of sodium carbonate required to make 1500g of the powder. Rx Calcium carbonate 5 parts Magnesium oxide 1 part Sodium carbonate 4 parts Bismuth subcarbonate 3 parts 235.6 g 346.2 g 576.9 g 115.4 g 461.5 g
1,000
How many grams of White wax should be added to 250 g of a 25% Zinc Oxide Ointment to make a 5% ointment? 100 1250 500 10,000 1,000
882.1
How many grams of sucrose must be dissolved in 475 mL of water to make a 65% (w/w) solution? 681.1 822.1 782.1 882.1 582.1
1000
How many mL of 1:500 (w/v) stock solution should be used to make 5 liters of a 1:2500 (w/v) solution? 1700 900 1000 1200 1500
120
How many mL of a liquid medicine would provide a patient with one teaspoonful thrice a day for 8 days? 240 480 360 120 60
700
How many mL of water should be added to 300 mL of a 1:750 (w/v) solution of benzalkonium chloride to make a 1:2500 (w/v) solution 800 1000 650 750 700
600
How many milligrams of procaine HCl should be used in preparing 120 suppositories each weighing 2 g and containing 1/4 % of procaine HCl? 240 120 60 0.25 600
40
How many milliliters if a 1:20 v/v solution of methyl salicylate in alcohol can be made from 100 mL fo 2% v/v solution? 40 25 60 38 30
725
How many milliliters of 50% w/v solution should be mixed with 2175 mL of 10% w/v solution to make a 20% w/v solution? 615 735 650 415 800
3125
How many milliliters of a 1:5000 (w/v) solution of phenyl mercuric nitrate can be made from 125 mL of a 0.5% solution? 1050 105 3125 5 80
48
How many wine gallons of 95% (v/v) alcohol would contain 91.2 proof gallons? 48 52 96 173 115
9.6 mg
How much Methylene Blue is needed to make 480 mL of a 1:50,000 solution? 5.2 mg 9.6 mg 7.1 mg 4.4 mg 4.8 mg
1
If 15 liters of Methylated Spirits is found to contain 15 mcL of Butanol, what is concentration of Butanol in ppm? 1 100 0.1 10 1000
10
If 5 mL of a 20% w/v aqueous solution of furosemide is diluted to 10 mL, what will be the final strength of furosemide? 5 20 15 10 30
30.0
If a cough syrup contains 0.24 g of codeine in 120 mL, how many milligrams are contained in each tablespoonful dose? 5.0 50.0 30.0 3.0 0.03
64.0
If a gallon of 30% (w/v) solution is to be evaporated so that the solution will have a strength of 60% (w/v), what will be its volume in fluidounces? 74.8 76.8 64.0 32.0 70.8
0.2%
If a patient is determined to have a serum cholesterol level of 200 mg/dL, express the cholesterol level in percentage. 2% 0.02% 0.2% 20% 200%
3.237
If a solution weighs 84.62 g in air and 58.48 g when immersed in water, what is its specific gravity? 4.327 2.327 3.237 3.732 7.323
2.4%
If five gallons of lotion contains one pound of talc, what is its percentage strength? 2.4% 3.6% 8.3% 6.7% 10.5%
3.75
If the usual adult dose of paregoric is 15 mL, what is the dose in milliliters for a child 4 years old 0.25 3.75 4.25 1.25 2.75
8
If two pints of guaifenesin elixir is present in the inventory, how many 4-fluid ounces prescription can be filed? 6 8 12 5 10
I and II
In a prescription: I. The full name and address of the patient are necessary for identification purposes II. The date is important to the pharmacist in filling prescriptions for controlled substances III. The name of the physician is necessary mainly for litigation purposes. I and III I only I, II, and III I and II
I, II, and III
In aqueous solutions, alcohol may precipitate in: I. agar II. Tragacanth III. acacia I, II, and III I and II II and III I and III
II and III
In filling the prescription, the pharmacist may select a container from among various shapes, color, sizes, mouth openings and composition. Which of the following are true regarding his selection? I. Prescription bottles are used to dispense viscous liquids II. Dropper bottles are used for dispensing ophthalmic, nasal, otic, or oral liquids to be administered by drop. III. Sifter-top containers are used for powders to be applied by sprinkling I and III I, II, and III I and II II and III
I only
In the stomach, In the stomach, which of the following would exist in its non-ionized form? I. aspirin II. Dextroamphetamine III. Chlorpheniramine I, II, and III III only I only I and II
8:5
In what proportion should 95% alcohol be mixed with 30% alcohol to make 70% alcohol? 45:30 8:5 25:40 2:3 3:7
hospital pharmacy
Institutional pharmacy is basically departmental pharmacy hospital pharmacy manufacturing pharmacy extended care pharmacy
on an empty stomach
Mineral oil as a laxative should be given: to children less than 6 years old Two of the choices dysphagic patients on an empty stomach
I only
Multivitamins if taken concomitantly by a patient on Tetracycline therapy would likely result to: I. decreased effectiveness of the antibiotic II. increased effectiveness of the antibiotic III. increased metabolism of the multivitamins I only I and II II and III II only
specialty hospital
National Children's Hospital is an example of a specialty hospital custodial hospital 2 of the choices general hospital
1962
PSHP was established in what year? 1942 1930 1962 1970
Ethanol
Patients taking chlorpropamide should avoid products containing: Acetaminophen Vitamin A Penicillin Ethanol
both physical and chemical incompatibility
Precipitation can be: chemical incompatibility physical incompatibility adverse drug reaction both physical and chemical incompatibility
4.8
Rx Salicylic acid 4% Menthol ½% T alc ad 120g How many grams of salicylic acid should be used in compounding the prescription? 3.0 4.0 4.8 3.8 5.0
4.848 g
Subtract 2.5 mg from 4.850g 48.48 g 2.35 g 4.848 g 2.53 g 4.8525 g
all of the above
Teratogenic drugs cause physical defects in developing fetus and this risk is highest during the first trimester. Which of the following is/are teratogenic drug/s? ACE inhibitor Tretinoin All of the above Warfarin
Type D ADR
Teratogenicity is a/an: Type A ADR Type B ADR Type C ADR Type D ADR
sorption
Term migration of the drug into the container. sorption leaching permeation vaporization
quality of drug therapy
The MAJOR reason for D.U.R. patient drug history quality of drug therapy drug cost drug administration
hydrolysis
The degradation reaction of ASA involves: hydrolysis oxidation photolysis racemization
Jonathan Roberts
The first person recognized as a hospital pharmacist: Jonathan Roberts Martin I Wilbert Charles Rice Robert Price
I, II, III, and IV
The following are risk factors for ADR I. Age II. Gender III. Co-morbidities IV. Genetics V. Patient Compliance I, II, IV, and V I, II, III, and IV I, II, and III only I, II, III, and V
indicated for Fe poisoning
The following are true about Dimercaprol except: British anti-Lewisite Indicated for Fe poisoning Chemical antagonist Indicated for As poisoning
64
The loading dose of chloramphenicol in enonates is 20 mg/kg of body weight. If the neonate weighed 7 lbs, what is the loading dose (mg)? 76 64 87 73 56
aplastic anemia
The most serious drug-induced blood disorder: leukemia agranulocytosis thrombocytopenia aplastic anemia
dispensing
The supply of medicine to an individual patient in accordance in the prescription given by the physician. formulation compounding dispensing manufacturing
antioxidants
These are added to drug formulations to prevent or reduce oxidation: complexing agents additives surfactants antioxidants
I, II, and III
These are factors responsible for the higher prevalence of ADRs in the geriatric populations: I. polypharmacy II. multiple disease states III. reduced drug elimination I, II, and III I and III I and II II and III
side-effect
These information should be indicated on the label of an extemporaneously compounded prescription, except name and quantity of ingredient direction for use side-effect date of filling
homodynamic
This describe drugs that elicit the same quality of effect and are mutually interactive, regardless of whether there is anything in common between the separate response systems. homodynamic homergic heterergic synergistic
tolerance
This is a phenomenin in which the physiological and/or psychological response to a substance is decreased with continuous use of the same dose od that substance. dependence withdrawal insanity tolerance
motion sickness
Transdermal Scopolamine is a drug used to prevent: coronary insufficiency motion sickness hypertension diabetes
patient compliance
Type F ADRs can occur as a result of the following, except: antimicrobial drug resistance drug instability patient compliance counterfeit drugs
concurrent
Type of DUR that uses current data retrospective none of the choices prospective concurrent
amber bottle
UV light-sensitive substances are best protected using: carbon box amber bottle plastic container flint glass
alkaloids
Water is most likely to cause instability on the following, except: benzodiazepines cephalosporins penicillins alkaloids
security
What is the most important storage condition for NARCOTIC DRUGS? moisture and light temperature sanitation security
5.25
What is the percentage of iodine in a mixture of 3 liters of 7% (w/v) iodine solution, 10 pints of 5% (w/v) solution and 2270 mL of 3.5% (w/v) solution? 5.0 6.17 5.25 10.0 7.15
Castor oil
Which laxative should be recommended to pregannat patients? mineral oil castor oil psyllium bisacodyl
rashes due to sudden change in temperature
Which may not lead to an adverse drug reaction? rashes due to sudden change in temperature overdose error in compounding use of wrong drug
paracetamol
Which of the following analgesics is safe and effective for pregnant patients? ibuprofen naproxen narcotic analgesics paracetamol
I, II, and III
Which of the following drugs are more than 90% bound to plasma proteins? I. Warfarin II. Phenylbutazone III. Penicillin I and II I, II, and III I and III II and III
Narcotic analgesic and drugs with anticholinergic properties
Which of the following drugs most commonly cause/s constipation? Drugs with anticholinergic properties narcotic analgesics ampicillin Narcotic analgesic and drugs with anticholinergic properties
I and III
Which of the following is/are true of a prescription? I. Inscription: Amoxicillin 500mg capsule II. Subscription: Amoxil 1 bottle for infection III. Transcription: 5mL once a day for 5 days I, II, and III I and II I and III I only
I, II, and III
Which of the following substances or compounds would tend to form a liquid or soft mass when brought in contact with camphor? I. Chloral hydrate II. Phenol III. Salicylic acid I and III II and III I, II, and III I and II
Riopan
Which one of the following antacid products is not a chemical combination of aluminum and magnesium hydroxides? Mylanta Gelusil Riopan Maalox
