Oral Antihyperglycemic- Biguanide  

Adverse / Side Effects:

- Hypoglycemia - Diarrhea, - nausea/vomiting,

Adverse / Side Effects: pt 2

- flatulence - indigestion - abdominal bloating

Drug Names:

Generic Name - metformin Brand Name - Glucophage

Nursing Considerations/ Priority Assessments: pt 2

· Discontinue temporarily (typically 48 hours before and 48 hours after) in patients undergoing radiology involving intravascular contrast materials

Nursing Considerations/ Priority Assessments:

· Given in divided doses with meals · Contraindicated in patients with kidney disease (serum creatinine greater than 1.5)

Mechanism of Action:

· Improves insulin sensitivity by increasing peripheral glucose uptake and utilization, decreases hepatic glucose production, decreases intestinal absorption

Adverse / Side Effects: pt 3

· Lactic acidosis (rare, but serious)

Nursing Considerations/ Priority Assessments: pt 3

· Monitor glucose and HbA1c levels · Contraindicated in patients with metabolic acidosis

Indications for Use:

· Type 2 Diabetes Mellitus