Oral Antihyperglycemic- Biguanide
Adverse / Side Effects:
- Hypoglycemia - Diarrhea, - nausea/vomiting,
Adverse / Side Effects: pt 2
- flatulence - indigestion - abdominal bloating
Drug Names:
Generic Name - metformin Brand Name - Glucophage
Nursing Considerations/ Priority Assessments: pt 2
· Discontinue temporarily (typically 48 hours before and 48 hours after) in patients undergoing radiology involving intravascular contrast materials
Nursing Considerations/ Priority Assessments:
· Given in divided doses with meals · Contraindicated in patients with kidney disease (serum creatinine greater than 1.5)
Mechanism of Action:
· Improves insulin sensitivity by increasing peripheral glucose uptake and utilization, decreases hepatic glucose production, decreases intestinal absorption
Adverse / Side Effects: pt 3
· Lactic acidosis (rare, but serious)
Nursing Considerations/ Priority Assessments: pt 3
· Monitor glucose and HbA1c levels · Contraindicated in patients with metabolic acidosis
Indications for Use:
· Type 2 Diabetes Mellitus