PATHO WEEK 3 QUIZ

A patient presents to the physician's office with pinpoint hemorrhages on the skin. The patient is most likely between the ages of _____ years

4 and 7

Which type of leukemia primarily affects children? A. ALL B. CLL C. AML D. CML

A. ALL acute lymphoid leukemia

Hapten mechanisms are found in which medications? (Select all that apply.)

- penicilin - cephalosporin - tetracycline

Patients who experience anemic episodes when exposed to certain drugs most likely have___________. A. thalassemia B. spherocytosis C. sickle cell anemia D. glucose 6 phosphate dehydrogenase deficiency

D. glucose 6 phosphate dehydrogenase deficiency

What laboratory finding is usually found in aplastic anemia? A. leukocytosis B. thrombocythemia C. neutrophilia D. pancytopenia

D. pancytopenia

The most common primary immune deficiency that affects only B cells is A. DiGeorge B. Bruton agammaglobulinemia C. Wiskott-Aldrich D. selective IgA

D. selective IgA

Burkitt lymphoma is most closely associated with

Epstein-Barr virus

Which of the following does not belong to a Myeloid neoplasm?

Hodgkin disease

In Myasthenia gravis, the neutrophils bind to target cells; and block receptors from normal functioning, causing injury to or malfunctioning involved tissue.

false

A patient is diagnosed with CML (chronic myeloid leukemia). The patient may experience which of these symptoms? (Select all that apply.)

fatigue, weight loss, abdominal discomfort, sweats

Red blood cells differ from other cell types in the body, because they

have no cytoplasmic organelles

Which condition is associated with an elevated reticulocyte count?

hemolytic anemia

The final step in clot formation is___________ A. conversion of prothrombin to thrombin B. platelet degranulation and adhesion C. conversion of fibrinogen to fibrin D. clot retraction

D. clot retraction

Which is correct about Hairy Cell Leukemia?

(these are correct) - rare chronic type of leukemia - 2% of adult leukemia but highly treatable - median age of presentation: 55 years; 5:1 predominance of males - B cell phenotype - peculiar cells with hairlike projections on their surface

Which is false about Vascular Purpura?

(these are true) - abnormality of the vessels or supportive tissues - purpura (patches of petechiae) present - allergic pjrpura: autoimmune process - ehlers-danlos syndrome: deficient collagen and elastin - vitamin c deficiency: defective collagen synthesis - aging: loss of subcutaneous fat and changes in connective tissue

Which is false about Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Disease)?

(these are true) - autosomal dominant trait - family history in both sexes - dilated, torturous small blood vessel that easily bleeds - vessel wall composed of single layer of endothelium - multiple elangiectases, repeated episodes of bleeding - treatment is supportive

Which is false about Hodgkin's Disease?

(these are true) - represents about 30% of malignant lymphoma - occurs across life span; half of cases between 20-40 years - higher incidence in males; also have worse prognosis - overall 5 year survival rate for all stages treated Hodgkin disease: 85%

Which is false about Disseminated Intravascular Coagulation (DIC)?

(these are true) - acquired hemorrhagic syndrome in which clotting and bleeding occur simultaneously. - causes may include: trauma, malignancy, burns, shock, and abruption placentae - widespread clot formation in small vessels; clotting factors and platelets consumed resulting in bleeding

Which are the primary functions of the circulatory system? (Select all that apply.)

- absorption and delivery of nutrients - oxygen uptake and delivery - removal of waste products

Which is false about Lymphoma (Non-Hodgkin)?

- do not have reed sternberg cells - majority arise from lymph nodes, but can originate in any lymphoid tissue - 95% occur in older adults - males somewhat higher risk than females - incidence increasing, especially in AIDS populations - most arise fro B cells, T cells, or NK cells

Treatment for hemophilia A includes........ A. heparin administration B. factor IX replacement C. factor VIII replacement D. platelet transfusion

C. factor VIII replacement

A deficiency of von Willebrand factor impairs__________ A. activation of the coagulation cascade B. platelet aggregation C. platelet adhesion to injured tissue D. platelet production

C. platelet adhesion to injured tissue

What is the correct definition of complete remission (CR) of leukemia?

CR is less than 5% blasts in marrow and normal CBC values

Which clinical finding is indicative of compartment syndrome?

absent peripheral pulses

This enzyme in the RBC helps to form carbonic acid.

carbonic anhydrase

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristics of which type of anemia?

iron deficiency

The cause of the most common form of anemia is

iron deficiency

Which characteristic is indicative of hemolytic anemia?

jaundice

Which causes vasoconstriction?

norepinephrine

The common complication of both disease process and diagnostic/treatment protocols of hematologic neoplasms is _________

pain

A patient is diagnosed with stage IIA Hodgkin disease. This patient's clinical stage was most likely determined by (Select all that apply.)

patient history, CT scan, physical examination

The megakaryocyte is a precursor to

platelets

The goal of long-term heparin for the management of a deep vein thrombosis is to

prevent further clot formation

The _________ means a normal total red cell mass with disturbances in the regulation of plasma volume.

relative anemia

What is the effect on resistance if the radius of a vessel is halved?

resistance increases by a factor of 16

The Lymphoma (Non-Hodgkin), can provoke two serious oncologic emergencies, and they are ______________ and ___________

superior vena cava obstruction and spinal cord compression

The activated partial thromboplastin time (aPTT) is a measure of the integrity of

the intrinsic pathway

This type of Hypersensitivity reaction is also known as the immune complex reaction

type III hypersensitivity

A newborn has melena, bleeding from the umbilicus, and hematuria. The newborn most likely experiencing

vitamin k deficiency bleeding