pharm final

HIV antiviral

enfuvirtide indinavir nevirapine (rash) zidovudine use 2 or more of these to reduce viral load

linezolid

VRE and MRSA myelosuppression (WBC, RBC, platelets)

carbonic anhydrase inhibitors

diuretics monitor K

erythromycin

take around the clock do not take with grapefruit juice do not take within 2 hr of dairy products or antacids reduces effectiveness of oral contraceptives mess with emotions

thiazide

HCTZ diuretics monitor K

clindamycin

can cause C-diff

polyenes

amphotericin B Nystatin- swish and swallow anti-fungal

metronidazole

anerobic antimicrobial drug

loop

furosemide diuretics monitor K

triazoles

fluconazole (1 pill for yeast infection) anti-fungal

imidazole

ketoconazole anti-fungal

tetracyclines

democlocycline tetracycline doxycycline minocycline tigecycline tooth discoloration, do not take with milk, antacids, iron salts, avoid pt under 8

osmotic

mannitol diuretics monitor K

vancomycin

MRSA and C-diff redman syndrome renal failure and ototoxicity

Potassium-sparing

Spironolactone diuretics monitor K

aminoglycosides

gentamicin neomycin streptomycin amikacin nephrotoxicity and ototoxicity monitor drug level to maximize drug efficacy and minimize toxicity, peak and trough

non-HIV antiviral

oseltamivir/zanamivir ribavirin (inhalation to treat RSV in infants, category X, use 2 forms of birth control) sofosbuvir amantadine/rimandine (forgetfulness) acyclovir ganciclovir (prevention, bone marrow suppression)