Pharmacology II Prep U Chapter 35: Hypothalamic and Pituitary Agents

Which hormone will be released in response to significant blood loss?

antidiuretic hormone (ADH)

A client is diagnosed with diabetes insipidus. The health care provider orders desmopressin, which the nurse knows is the synthetic equivalent of what hormone?

ADH

Pegvisomant is used to treat which disorder?

Acromegaly

The nurse is aware that somatropin is not appropriate for the person who exhibits growth impairment and what other condition?

Closure of the epiphyseal plate

Which would be used to diagnose adrenal function?

Corticotropin

After administering desmopressin to a client with diabetes insipidus, which would the nurse identify as indicating drug effectiveness?

Decrease reports of thirst

An instructor is preparing a teaching plan about hypothalamic agents. Which would the nurse include as a hypothalamic agonist?

Nafarelin

The nurse is caring for a patient who is receiving desmopressin, a posterior pituitary hormone. Why is it important for the nurse to read the instructions for use before administering this drug?

Pituitary hormones require special techniques of administration.

When describing desmopressin to a group of students, the instructor explains that it is a synthetic form of:

antidiuretic hormone

Deficiency of which hormone causes polyuria and polydipsia?

antidiuretic hormone (ADH)

What is the regulatory function of vasopressin?

water balance

What is true of the hormone vasopressin? (Select all that apply.)

• Vasopressin is secreted when body fluids must be conserved. • Vasopressin regulates the reabsorption of water from the kidney.

What effect do growth hormones (GH) have on homeostasis? Select all that apply.

* regulation of cell division * regulation of protein synthesis * stimulation of triglyceride synthesis

A client receives desmopressin intravenously at 10:00 AM. The nurse would expect the drug to begin working at which time?

10:30 AM

Somatropin would be prescribed for which of these patients?

A 5-year-old with short stature and Turner syndrome

Deficiency of which hormone causes excessive and frequent urination and excessive thirst?

ADH deficiency

A client is to undergo fertility treatment and is to receive an agent that induces ovulation because her ovaries are functioning. Which agent would this most likely be?

Chorionic gonadotropin

A child is receiving growth hormone therapy. The nurse suspects possible thyroid dysfunction based on which assessment?

Cold intolerance

Desmopressin is used to treat which endocrine disorders?

Diabetes insipidus

Lack of antidiuretic hormone (ADH) produces which disease process?

Diabetes insipidus

A head injury has resulted in the hospitalization of a client. Nursing assessments confirm that the client is producing substantial amounts of dilute urine and is consuming large amounts of liquids. Considering the history and assessment findings support the possibility of what metabolic disorder?

Diabetes insipidus (DI)

The pediatric nurse understands that growth hormone (GH) deficiency can cause which disorder?

Dwarfism

A client is diagnosed with syndrome of inappropriate antidiuretic hormone (SIADH) and has been prescribed a medication to affect the posterior pituitary gland's production of antidiuretic hormone (ADH). Which nursing assessment is critical to this client's safety?

Fluid balance

The nurse would know it is most important to monitor which laboratory test in a client who is receiving lanreotide?

Glucose level

The nurse would contact the health care provider prior to administering desmopressin to a client with a history of what condition?

Heart attack

A clinic nurse is following a 9-year-old boy who is taking somatropin. What will the nurse monitor periodically?

Height

What is the route of administration for bromocriptine?

Oral

A patient is experiencing a prolonged labor and her contractions are ineffective. Which agent would the nurse expect to be ordered?

Oxytocin

Antidiuretic hormone functions by causing all of the following EXCEPT:

Inhibiting secretion of thyrotropin.

A client is to receive nafarelin. The nurse would instruct the client in administering this drug by which route?

Intranasal

Which is a factor that inhibits the release of hormones?

Somatostatin

After teaching a group of students about growth hormone agonists and antagonists, the instructor determines that additional teaching is needed when the students identify which agent as a growth hormone antagonist?

Somatropin

Which agent would the nurse identify as a growth hormone agonist?

Somatropin

The nurse is preparing to administer octreotide. The nurse expects to administer this drug by which route?

Subcutaneous

A client's current drug regimen includes intranasal administration of desmopressin acetate. In this client's plan of nursing care, what is the most likely desired outcome of treatment?

The client's urine output will not exceed 80 mL/h.

A 13-year-old boy who is in the first percentile of height for his age has been referred for care. Which assessment finding would contraindicate the safe and effective use of somatropin to treat his growth deficiency?

The epiphyses of the boy's long bones have closed.

The nurse is assessing a child who is receiving growth hormone therapy. What would the nurse identify as suggesting glucose intolerance?

Thirst

An adult client diagnosed with human immunodeficiency virus (HIV) is prescribed somatropin (Serostim). The nurse should explain that this drug is primarily used in HIV clients for which purpose?

To stop severe muscle wasting

Which hormone is released in the presence of low blood volume?

antidiuretic hormone (ADH)

Which instructions would be an important component of teaching a patient to self-administer nasal spray?

Use a firm squeeze to deliver the drug.

What is the most effective method to determine a client's ability to self-administer their prescribed nasal desmopressin?

Watch them administer a scheduled dose of the medication.

Gonadotropins are classified in which pregnancy category?

category X

Which hormone stimulates the adrenal cortex to produce and secrete adrenocortical hormones?

corticotropin

What causes the release of adrenocorticotropic hormone in response to a client's psychological and physiological stress?

corticotropin-releasing hormone or factor (CRH or CRF)

Drugs administered to influence hypothalamic hormones typically have half-lives of:

days to weeks

A nurse is organizing the care of a child who takes somatotropin. The desired outcome the nurse should prioritize in the planning of this child's care is that the client will:

demonstrate in increase in linear growth.

Which hormone will be released in response to the increase in the size and number of muscle cells?

growth hormone

A 65-year-old client was involved in a motor vehicle accident and sustained a closed head injury. He is diagnosed with diabetes insipidus and is prescribed vasopressin for the management of this condition. Which condition would pose a risk for this client as a vasopressin recipient?

has a history of left ventricular enlargement

A 7.5-year-old female has received a diagnosis of precocious puberty from the pediatric endocrinologist. The nurse should prepare to educate the child and her parents on what drug?

leuprolide acetate

What medication is prescribed for the treatment of infertility?

mentotropins

Growth hormone (GH) hypersecretion is usually caused by:

pituitary tumors

The hypothalamus releases hormones that act as:

releasing factors

In light of the black box warning that accompanies desmopressin, the ICU nurse should prioritize the assessment of which of the client's laboratory values?

sodium

A critically ill client is being treated with desmopressin. When reviewing the diagnostic and laboratory findings of a client prescribed desmopressin, the nurse should prioritize what values?

sodium (Na)

Which hormones are responsible for the growth of the body during childhood, especially the growth of muscles and bones?

somatotropin

Which needs to be used in a child prior to the closure of the bone epiphyses in order to exert its effects?

somatropin

The control mechanisms for most metabolic functions of the body, as well as the maintenance of homeostasis, is the function of:

the hypothalamus and the pituitary gland.

Diabetes insipidus is treated with replacement of which hormones?

vasopressin

Which hormones are responsible for the regulation of reabsorption of water by the kidneys?

vasopressin

A diagnosis of precocious puberty primarily considers what client-focused factor? Select all that apply.

• age • race • secondary sexual characteristics