puberty

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female peak height velocity chart

11y fastest growth (6mo before menarche)

male peak height velocity chart

14y fastest growth

what is menarche?

1st period usually 2.5y post-thelarche

how much of bone calcium is set pre-puberty?

50% in F 50-66% in M

what is adrenarche?

=pre-pubescent adrenal medulla activation = Tanner stage I -> adrenal androgen production -> goadarche/puberty

what part of the brain matures last?

DLPFC: executive thinking, planning, coord

what is considered delayed puberty?

F 13, M 14 wo Sx of puberty (>2SD from avg) common: constitutional, largely FHx rare: hypo/hypergonadotropic hypogonadism

when does premature thelarche occure?

F 6mo-3y

when does premature adrenarche occure?

F <6-7yo M <9yo

what is considered precocious puberty?

F<8, M<9 central: premature HPG axis activation periph: gonadarche/adrenarche wo HPG axis

what is gonadarche?

FSH, LH-stimulated gonad activation: puberty

what are the biochemical changes associated with puberty?

Hb: anemia in M/F, ^Hb in males (^testosterone) gynecomastia in 50% M acne psych changes: depression higher in F M/S injury, esp Osgood-Schlatter (patellar lig) gyn: DUB myopia scoliosis

what is Tanner stage IV?

M: genitals mature F: areola + papilla raised about breast

what is Tanner stage III?

M: penile growth F: breast growth

what is Tanner stage II?

M: testicular volume F: thelarche

what is the Tanner stage I?

adrenarche/prepuberty

which grow first: distal or proximal?

distal growth >> proximal

what are the 3 age stages of adolescence?

early 11-14: concrete thinking, same sex peers middle 15-17: abstract thinking, M/F, risk late 17-21: formal thinking, planning, partners

what is Tanner stage V?

full adult development of genital tissues

what may be the biochemical initiator of puberty?

leptin

how to calculate predicted height?

midparental F: (Father-13cm+Mother)/2 M: (Father+Mother+13cm)/2

what is thelarche?

the development of breast tissue 1st sign of puberty in females predates menarche by ~2.5y

what is pubarche?

the development of pubic hair


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