RQ 4-4

Which of the following best describes "alternative splicing?" a) It occurs when different combinations of exons are kept in the processed mRNA b) It occurs when different combinations of introns and exons are kept in the processed mRNA c) It occurs when no introns are kept in the processed mRNA d) It occurs when different combinations of introns are kept in the processed mRNA

a) It occurs when different combinations of exons are kept in the processed mRNA

What is a "coding region" (or "Open Reading Frame") of a gene or mRNA? a) The part that codes for protein from the first 5'AUG3' to the stop codon b) The 3' end of the gene c) The 5' end of the gene d) The parts of the gene that are transcribed but are not translated

a) The part that codes for protein from the first 5'AUG3' to the stop codon

Roughly what percent of human protein-coding genes are thought to be alternatively spliced? a) 2% b) over 90% c) 50% d) 30%

b) Over 90%

What does the "spliceosome" consist of? (Choose ALL correct answers) a) Polysaccharide b) Protein c) RNA d) Lipids

b) Protein c) RNA

Which part of the spliceosome actually catalyzes the breaking of phosphodiester bonds between exons and introns? a) The lipids b) The snRNA c) The carbohydrates d) The proteins

b) The snRNA

Which parts of a processed eukaryotic mRNA are also found within the DNA that the mRNA was transcribed from? (Choose ALL correct answers) a) The poly-A tail b) The m7G cap c) 5' untranslated region (5' UTR) d) Exons

c) 5' untranslated region (5' UTR) d) Exons

Which of the following will have a polyadenylation (PolyA) signal sequence (Choose ALL correct answers) a) Primary rRNA transcript b) Primary tRNA transcript c) Primary mRNA transcript

c) Primary mRNA transcript

What happens to nucleic acid strands that are spliced out of an mRNA? a) They are translated into protein b) They are transported out of the nucleus c) They are degraded down into individual nucleotides d) They are combined with other strands of RNA

c) They are degraded down into individual nucleotides

What do the 5' Me-G Cap and the 3' poly-A tail do? a) Make the mRNA form a circle b) Help RNA polymerase transcribe faster c) Tell the spliceosome where to splice the mRNA d) Protect the mature mRNA from degradation by ribonucleases

d) Protect the mature mRNA from degradation by ribonucleases

If the mRNA from a gene is alternatively spliced in different cell types... a) The mature (processed) mRNA in each cell type will be the same b) The proteins in each cell type will be the same c) The primary mRNA in each cell type will be different d) The proteins in each cell type will be different

d) The proteins in each cell type will be different