Water Soluble Vitamins Quiz

High intakes of pyridoxine greater than 100 mg/d may cause ________.

neuropathy

NADPH produced in the hexose monophosphate shunt is a reduced form of one of the coenzyme structures of which vitamin?

niacin

Tryptophan catabolism diverts about 3% of dietary intake to the liver synthesis of which vitamin?

niacin

Vitamin C is important in collagen synthesis because it acts:

to restore iron to a reduced state.

Beriberi is a symptom of deficiency of which vitamin?

thiamin

Transketolase is an enzyme in the hexose monophosphate shunt that requires which of the following vitamins as a coenzyme?

thiamin

B complex vitamins important for hematopoiesis include all of the following EXCEPT ________

thiamin(Folic acid, vitamin B12, Vitamin B6 are important for hematopoiesis)

Folate in supplements is more easily absorbed than folate in food, making one dietary folate equivalent (DFE) equal to one mcg food folate and ________ mcg from a supplement or fortified food consumed with a meal.

0.6 mcg

Although excess absorbed ascorbic acid is excreted in urine, the body has an estimated maximal body pool of 1500 mg which can be maintained with intakes of ________ vitamin C per day.

100-200 mg

Acting as a coenzyme is a major function of:

B vitamins

Symptoms of pellagra include____.

Dermatitis, dementia, diarrhea, and death

Vitamin C is important in wound healing and maintenance of skin, tendons, cartilage, bone and dentine due to its importance to which enzyme?

Prolyl Hydroxylase

Which of the following vitamins is important for entry of long-chain fatty acids into the mitochondrial matrix?

Vitamin C

Nutrients can affect expression of our genes in all of the following ways except one; thus nutrients CANNOT:

alter the base sequence of DNA in a cell.

Vitamin B6 is a coenzyme for > 100 enzymes mostly involved in ______

amino acid metabolism

Vitamin C acts in all of the following capacities EXCEPT:

antirachitic agent (it acts as a reducing agent, prooxidant, and antioxidant)

Which vitamin is a coenzyme needed for particular enzymes to add a carboxyl group to an existing molecule?

biotin

A genetic deficiency of what enzyme is associated with these symptoms: lethargy, depression, hallucinations, muscle pain, paresthesia in extremeties, anorexia, nausea, alopecia, and red dermatitis?

biotinidase

Thiamin plays major roles in all of the following EXCEPT:

collagen formation.(It plays major roles in Synthesis of pentoses and NADPH, energy transformation, and membrane and nerve conduction)

When water-soluble vitamins are found in urine in healthy individuals, it generally means that they have been:

consumed in excess of body needs

Tetrahydrofolate is vitally important for dividing cells during growth and cancer and knowledge of this need is used in cancer treatment by giving the drug Methotrexate to inhibit the enzyme ________.

dihydrofolate reductase

Which group of individuals is most likely to have a vitamin B12 deficiency?

elderly Caucasians or vegans

Ingested folate requires the addition of ________ to make it active as a coenzyme.

four hydrogens

A vitamin B12 deficiency is usually associated with lack of adequate ________.

intrinsic factor

Flavoproteins are especially important in ________.

oxidation reduction reactions

Which of the water-soluble vitamins is a component of acyl carrier protein, a necessary part of the fatty acid synthase complex?

pantothenic acid

Which vitamin, as part of coenzyme A, forms thio esters with carboxylic acids such as succinic acid and acetic acid?

pantothenic acid

Vitamin B6 functions importantly in all of the following EXCEPT _______

synthesis of fatty acids (does function in glycogen breakdown, transamination of amino acids, synthesis of niacin)

FMN is required for the metabolism of what other vitamin to its primary coenzyme form?

vitamin B6

Hypochromic, microcytic anemia is a deficiency symptom of inadequate intake of _______

vitamin B6