AP2 Mastering Ch 22 Immunity

Immunoglobulins that are found on the surface of B cells and that may activate antibody production are IgA. IgD. IgE. IgG. IgM.

IgD

Immunoglobulins that attach to and sensitize mast cells and basophils are IgA. IgD. IgE. IgG. IgM.

IgE.

Immunoglobulins that are most abundant and are responsible for resistance against many viruses, bacteria, and bacterial toxins are IgA. IgD. IgE. IgG. IgM.

IgG.

The cells that perform immunological surveillance are the ________ cells. suppressor T NK plasma B helper T

NK

If the thymus shrank and stopped making thymosins, we would expect to see an immediate decrease in the number of B lymphocytes. NK cells. neutrophils. T cells. red blood cells.

T cells.

The term lymphadenopathy refers to a congenital lack or malformation of lymph nodes. accumulations of lymph in the tissue space. the lack of lymphocytes in peripheral circulation. increased numbers of circulating lymphocytes. a chronic or excessive enlargement of lymph nodes.

a chronic or excessive enlargement of lymph nodes.

All of the following are true of the thymus gland except that it involutes after puberty. reaches its greatest relative size during the second year of life. activates B cells. lies in the anterior mediastinum. produces T cells.

activates B cells.

Different mechanisms of cytoxoxic T cell destruction include all of the following EXCEPT __________. stimulating apoptosis secreting perforins activation of CD4 marker response to antigen presentation disrupting cell metabolism

activation of CD4 marker response to antigen presentation

Antigens that trigger allergic reactions are called interferons. agglutinins. microbes. allergens. pyrogens.

allergens.

Lymphatic capillaries are known for all of the following except being the starting point of the lymphatic circulation. having shingle-like endothelial cells. having larger diameters and looser walls than blood capillaries. allowing nutrient and gas exchange. being the smallest lymphatic vessels.

allowing nutrient and gas exchange.

A substance that provokes an immune response is called an immunoglobulin. allopath. antihistamine. antigen. antibody.

antigen.

When the immune response mistakenly targets normal body cells and tissues, a(n) ________ develops. allergic response agglutination reaction autoimmune disease immunodeficiency disease cross-reaction

autoimmune disease

The cells directly responsible for cellular immunity are the ________ cells. plasma dendritic cytotoxic T helper T suppressor T

cytotoxic T

When an antigen is bound to a Class I MHC molecule, it can stimulate a ________ cell. helper T cytotoxic T B plasma NK

cytotoxic T

CD8 markers are to ________ T cells as CD4 markers are to ________ T cells. plasma; NK NK; cytoxic suppressor; cytoxic cytoxic; helper helper; suppressor

cytoxic; helper

The movement of phagocytes through the capillary wall is called chemotaxis. diapedesis. adherens. transcytosis. diffusion.

diapedesis.

Cells that help regulate the immune response are ________ cells. cytotoxic T B NK plasma helper T

helper T

When an antigen is bound to a Class II MHC protein, it can activate a ________ cell. helper T NK suppressor T plasma cytotoxic T

helper T

Which class of T lymphocyte is killed by the AIDS virus? NK suppressor T cytotoxic T helper T

helper T

Class II MHC molecules are found on which of the following? liver cells and macrophages in the spleen granulocytes and microphages all body cells with a nucleus red blood cells lymphocytes and antigen-presenting cells

lymphocytes and antigen-presenting cells

An inflammatory response is triggered when T cells release interferon. blood flow to an area increases. red blood cells release pyrogens. mast cells release histamine and heparin. neutrophils phagocytize bacteria.

mast cells release histamine and heparin.

Immunity that results from antibodies that pass through the placenta from mother to fetus is called ________ immunity. artificially acquired passive naturally acquired passive naturally acquired active innate artificially acquired active

naturally acquired passive

Lymph fluid enters the venous circulation via the right atrium. subclavian veins. jugular veins. brachiocephalic trunks. superior and inferior vena cava.

subclavian veins.

Lymphatic tissue is found in the greatest quantity in bone marrow. the adult spleen. the tonsils. the adult thymus. Peyer's patches.

the adult spleen.

A measure of antibody level in the plasma is the primary response. the secondary response. body temperature. antigen concentration. the antibody titer.

the antibody titer.

Leslie has a severe sore throat and the lymph nodes in her neck are swollen. This would indicate that the focus of the infection is the lymph nodes. lymph is not flowing consistently through these lymph nodes. the lymph nodes contain an increased number of lymphocytes. the lymph nodes are actively producing phagocytes. the lymph nodes have increased their secretion of thymosin.

the lymph nodes contain an increased number of lymphocytes.

The lymphatic system is composed of all of the following except lymph nodes. lymph. the venae cavae. lymphatic vessels. the spleen.

the venae cavae.

T is to ________ as B is to ________. top-located; bottom-located non-thymus-dependent; bottom-located thymus-dependent; bone marrow-derived thyroid-drawn; bowel-developed trabeculae-descended; bursa-origin

thymus-dependent; bone marrow-derived

Large lymphatic vessels have a wall structure most similar to which blood vessel? veins capillaries arteries venules arterioles

veins

The following are steps in the cell-mediated immune response. What is the correct sequence for these steps? 1. Several cycles of mitosis occur. 2. Antigen is engulfed and presented by a macrophage. 3. Cytotoxic T cells migrate to focus of infection. 4. T cells with specific receptors recognize the antigen. 5. T cells differentiate into cytotoxic T cells or T memory cells. 6. Cytotoxic T cells release perforin and/or lymphotoxin. 3, 2, 4, 1, 5, 6 2, 4, 1, 5, 3, 6 4, 1, 5, 3, 6, 2 3, 6, 4, 5, 1, 2 1, 2, 4, 5, 3, 6

2, 4, 1, 5, 3, 6

The cells responsible for humoral immunity are the ________ cells. helper T suppressor T B NK cytotoxic T

B

T cells and B cells can be activated only by cells infected with viruses, bacteria, or cancer cells. interleukins, interferons, and colony-stimulating factors. disease-causing agents. exposure to a specific antigen at a specific site in a plasma membrane. pathogens.

exposure to a specific antigen at a specific site in a plasma membrane.

The first line of cellular defense against pathogens are the B cells. phagocytes. T cells. plasma cells. NK cells.

phagocytes.

The release of endogenous pyrogen (or interleukin-1) by active macrophages would opsonize pathogens. activate antibodies. activate complement. produce a fever. cause inflammation.

produce a fever.

Stem cells that will form B cells or NK cells are found only in the red bone marrow. kidneys. liver. thymus. spleen.

red bone marrow.