Celiac Disease - Pathophysiology and Etiology
Etiology
Intestinal mucosa damaged by immunologic response.
Secondary complications of Celiac
Intestinal ulceration and development of refractory disease, or disease that no longer responds to a gluten free diet.
Celiac is characterized by:
Sensitivity to the gliadin fraction of gluten.
Symptoms
Abdominal pain, bloating, cramps, diarrhea, steatorrhea, anemia, small stature, delayed maturity, tetany, vitamin deficiencies, muscle wasting, rickets.
Celiac Disease
Chronic immune mediated disorder of the small intestine in which the absorption of nutrients, particularly fats, is impaired.
Risk factors
Familial forms of celiac disease, iron-deficiency anemia, osteopenic bone disease, insulin-dependent diabetes, and genetic disorders such as down syndrome and turner syndrome