Ch 50 Antineoplastic Drugs

A nurse should monitor a client closely for increased seizure activity when which of the following antineoplastic drugs are used concomitantly with phenytoin (Dilantin)? Select all that apply. A) Mercaptopurine (Purinethol) B) Busulfan (Busulfex) C) Thiotepa (Thioplex) D) Doxorubicin (Doxil) E) Irinotecan (Camptosar)

B, C, E

A client is receiving an alkylating agent. Which of the following would be used? Select all that apply. A) Bleomycin (Blenoxane) B) Chlorambucil (Leukeran) C) Vinblastine (Velban) D) Cyclophosphamide (Cytoxan) E) Ifosfamide (Ifex)

B, D, E

Which of the following should be included in the nurse's preadministration assessment before administering the first dose of an antineoplastic drug? Select all that apply. A) Blood glucose B) Weight C) Fasting lipid panel D) Blood pressure E) Temperature

B, D, E

A client has been prescribed melphalan for the treatment of an ovarian tumor. The client wants to know how the drug acts. Which of the following would the nurse integrate into the response? A) Increased acidity of the cell environment B) Change to a more alkaline cell environment C) Neutralization of the alkalinity of the cell environment D) Change in the cell to a neutral environment

B.

A client has been receiving treatment with antineoplastic drugs that depress the bone marrow. Which preadministration assessment would be most important for the nurse to complete with respect to this effect? A) Evaluating the emotional response to the disease B) Obtaining a complete blood count C) Checking fluid intake and output D) Evaluating the client's understanding of therapy

B.

Which of the following cytoprotective agents can be given along with antineoplastic drugs to help prevent or lessen certain adverse effects? Select all that apply. A) Allopurinol (Zyloprim) B) Amifostine (Ethyol) C) Leucovorin (Wellcovorin) D) Mesna (Mesnex) E) Dexrazoxane (Zinecard)

A, B, C, D, E

A nurse should understand that which of the following adverse effects of antineoplastic drugs are related to the death of rapidly growing cells? Select all that apply. A) Alopecia B) Leukopenia C) Stomatitis D) Cardiotoxicity E) Thrombocytopenia

A, B, C, E

If the nurse has to clean up a spill of antineoplastic drug, which of the following personal protective equipment should be worn? Select all that apply. A) Gloves B) Safety goggles C) Gown D) Chemical spill boots E) NIOSH-approved respirator

A, B, C, E

The primary health care provider prescribes an antineoplastic antibiotic. The nurse identifies which of the following as a possibility? Select all that apply. A) Bleomycin (Blenoxane) B) Carboplatin (Paraplatin) C) Dactinomycin (Cosmegen) D) Daunorubicin (DaunoXome) E) Busulfan (Busulfex)

A, C, D

After teaching a group of nursing students about antineoplastic drugs, the instructor determines that the teaching was successful when the students identify which of the following as being classified as a plant alkaloid? Select all that apply. A) Vincristine (Oncovin) B) Capecitabine (Xeloda) C) Paclitaxel (Taxol) D) Etoposide (Toposar) E) Irinotecan (Camptosar)

A, C, D, E

A client is receiving doxorubicin. The nurse suspects that extravasation has occurred based on assessment of which of the following? Select all that apply. A) Swelling B) Petechiae C) Lack of blood return D) Urticaria E) Redness

A, C, E

A nurse should monitor a client closely for signs of worsening atrial fibrillation when which of the following antineoplastic drugs are used concomitantly with digoxin (Lanoxin)? Select all that apply. A) Mercaptopurine (Purinethol) B) Busulfan (Busulfex) C) Thiotepa (Thioplex) D) Doxorubicin (Doxil) E) Irinotecan (Camptosar)

A, D, E

A nurse is discussing the possible adverse reactions that may occur with antineoplastic therapy. Which of the following would the nurse discuss as examples of long-term adverse reactions? Select all that apply. A) Fertility problems B) Thrombocytopenia C) Leukopenia D) Stomatitis E) Cardiotoxicity

A, E

A client visits the health care facility for information on cancer. The client asks the nurse if regular consumption of green tea can cause harm. Which of the following should the nurse inform the client as possible effects of green tea? A) Dental caries B) Damage to heart C) Insomnia D) Damage to liver

C

Which of the following alkylating agents can cross the blood-brain barrier? Select all that apply. A) Cisplatin (Platinol-AQ) B) Melphalan (Alkeran) C) Carmustine (BiCNU) D) Streptozocin (Zanosar) E) Mechlorethamine (Mustargen)

C, D

A client is to start chemotherapy. The client is worried about going bald in the course of the treatment. How can the nurse assist the client in being comfortable with her body image? A) Forewarn about hair loss as permanent B) Explain it is not life-threatening C) Suggest the use of a wig or cap D) Explain that hair preserves body heat

C.

A client has been diagnosed with cancer. The physician prescribes antineoplastic drug therapy to the client. Which of the following would the nurse include in the discussion about the prescribed therapy? A) Leads to complete cure of cancer B) Destroys only cancerous cells C) Provides complete relief of symptoms of cancer D) Delays spread of cancer to other sites

D.

A client is receiving cisplatin. Based on the nurse's understanding that this drug can be nephrotoxic, the nurse anticipates that the primary health care provider will prescribe which of the following? A) Mesna B) Leucovorin C) Dexrazoxane D) Amifostine

D.

A nurse is caring for a client who is prescribed Velban, a vinca alkaloid. The client asks the nurse about how the drug acts. Which of the following would the nurse integrate into the response? A) Interference with amino acid production in the S phase B) Stoppage of cells during the S and G2 phases C) Inhibition of DNA synthesis during the S phase D) Prevention of cell division during the S and G2 phases

A.

A nurse is preparing to administer an antineoplastic drug that is classified as an antimetabolite. Which of the following might the nurse be preparing to give? Select all that apply. A) Mercaptopurine (Purinethol) B) Capecitabine (Xeloda) C) Fluorouracil (Adrucil) D) Etoposide (Toposar) E) Irinotecan (Camptosar)

A, B, C

A nurse notifies the primary health care provider because assessment reveals signs of thrombocytopenia, including which of the following? Select all that apply. A) Bleeding gums B) Petechiae C) Tarry stools D) Hematuria E) Coffee-ground emesis

A, B, C, D, E

After administering an antineoplastic drug, the nurse bases the ongoing assessment on which of the following factors? Select all that apply. A) Client's general condition B) Client's individual response to the drug C) Adverse reactions that may occur D) Guidelines established by the oncology physician or clinic E) Results of periodic laboratory tests and radiographic scans

A, B, C, D, E

The nurse suspects that a client is developing leukopenia and notifies the primary health care provider based on assessment of which of the following? Select all that apply. A) Temperature of 100.4°F or higher B) Cough C) Sore throat D) Frequent urination E) White blood cell count of less than 2500/mm3

A, B, C, D, E

A nurse is caring for a client being treated with antineoplastic drugs. The client is at risk for thrombocytopenia due to bone marrow suppression. The nurse would assess the client for which of the following? A) Bloody urine B) Concentrated urine C) Frequent micturition D) Pain on urination

A.

After teaching a group of nursing students about the cell cycle and how it relates to antineoplastic drugs, the instructor determines that the teaching was successful when the students identify which phase of the cell cycle as being affected by antimetabolites? A) S phase B) M phase C) G2 phase D) G1 phase

A.

The nurse is providing care to a client with anorexia due to antineoplastic therapy. The nurse identifies a nursing diagnosis of Imbalanced Nutrition: Less Than Body Requirements. Which of the following would be least appropriate for the nurse to include in the client's plan of care? A) Offering fatty foods to stimulate the taste buds B) Providing small, frequent meals C) Avoiding exposure to unpleasant smells D) Providing foods that are high in protein

A.

A group of nursing students are reviewing antineoplastic drugs. The students demonstrate understanding of the information when they identify which of the following as cell cycle specific? Select all that apply. A) Alkylating agents B) Plant alkaloids C) Antimetabolites D) Antineoplastic antibiotics E) Retinoids

B, C

Which of the following are examples of immediate adverse reactions to an antineoplastic drug that the nurse should discuss with the client prior to drug administration? Select all that apply. A) Fertility problems B) Extravasation C) Nausea D) Cardiotoxicity E) Pulmonary fibrosis

B, C

A nurse is caring for a client who is at risk for erythema during antineoplastic drug therapy. The nurse identifies a nursing diagnosis of Impaired Tissue Integrity. Which of the following would be appropriate to suggest? A) Scrub and clean skin often. B) Wear loose protective clothing. C) Ensure adequate sunlight. D) Have frequent baths.

B.

A nurse is caring for a client undergoing treatment with plant alkaloids for cancer. The client is also receiving warfarin for a history of atrial fibrillation. The nurse would monitor the client for which of the following as a possible interaction? A) Increased risk of seizures B) Increased risk of ototoxicity C) Increased risk of CNS depression D) Increased risk of prolonged bleeding

D.