Chapter 3 Quiz

Kupffer cells would be found in?

liver

Histiocytes would be found in?

in the tissues

Macrophages would be found in?

lympho nodes, liver

Microglial cells would be found in?

the brain

Arrange the steps of phagocytosis in the proper sequence: A) Digestion of bacteria B) Increase in Chemoattractants at site of tissue damage C) Ingestion of bacteria D) Movement of phagocytic cells

1. B) Increase in Chemoattractants at site of tissue damage 2. D) Movement of phagocytic cells 3. C) Ingestion of bacteria 4. A) Digestion of bacteria

Match the appropriate monocyte-macrophage abnormality with its respective condition: _______ Defective monocyte cytotoxicity A) Wiskott-Aldrich syndrome B) Burns or diabetes C) Systemic lupus erythematosus D) Corticosteroid therapy E) Intracellular infections

A) Wiskott-Aldrich syndrome

The site of hematopoiesis in the first month of gestation is the: A) Yolk sac B) Spleen C) Liver D) Bone Marrow

A) Yolk Sac

A primary function of the eosinophil is: A) Phagocytosis B) Suppression of the inflammatory response C) Reacting in acute, systemic hypersensitivity reactions D) Antigen recognition

B) Suppression of the inflammatory response

Arrange the sites of blood cell development (hematopoiesis) in the embryo and fetus in the correct sequence of development: ______ Site of initial red blood cell production A) Liver and spleen B) Yolk sac C) Bone marrow

B) Yolk sac

Arrange the sites of blood cell development (hematopoiesis) in the embryo and fetus in the correct sequence of development: ______ Ultimate site of primary hematopoiesis A) Liver and spleen B) Yolk sac C) Bone marrow

C) Bone marrow

Match each disorder or deficiency to its characteristics: ______ Myeloperoxidase deficiency A) Marked defect in cellular response to chemotaxis B) Failure to exhibit increased anaerobic metablolism during phagocytosis C) Mild to marked defect in bactericidal ability of neutrophils D) Defective leukocyte locomotion

C) Mild to marked defect in bactericidal ability of neutrophils

Match the following cell types to their respective functions. (An answer can be used more than once.) ______ Lymphocytes A) Primary phagocytic cells B) Antibody-synthesizing cells C) Recognition of foreign antigen and production of antibody

C) Recognition of foreign antigen and production of antibody

Match the appropriate monocyte-macrophage abnormality with its respective condition: _______ Imparied phagocytosis A) Wiskott-Aldrich syndrome B) Burns or diabetes C) Systemic lupus erythematosus D) Corticosteroid therapy E) Intracellular infections

C) Systemic lupus erythematosus

Which statement about eosinophils is false? A) They are homeostatic regulators of inflammation B) They attempt to suppress an inflammatory reaction C) They participate in hypersensitivity reactions D) They interact with the larval stages of some helminth parasites

C) They participate in hypersensitivity reactions

Which statement about basophils is false? A) They have a high concentration of heparin in the granules B) They have a high concentration of histamine in the granules C) They react with two adjacent IgA molecules on mast cells D) They are associated with anaphylactic shock.

C) They react with two adjacent IgA molecules on mast cells

Patients with a marked decrease in neutrophils or severe defects in neutrophil function have: A) A high rate of infection B) Recurrent systemic bacterial infections C) Recurrent life-threatening fungal infections D) All of the above

D) All of the above

The cells of the mononuclear phagocyte system include: A) Monocytes and promonocytes B) Monocytes and macrophages C) Lymphocytes and Monocytes D) Both A and B

D) Both A and B

Match the appropriate monocyte-macrophage abnormality with its respective condition: _______ Defect in phagocytic killing A) Wiskott-Aldrich syndrome B) Burns or diabetes C) Systemic lupus erythematosus D) Corticosteroid therapy E) Intracellular infections

D) Corticosteroid therapy

Match each disorder or deficiency to its characteristics: ______ Lazy leukocyte syndrome A) Marked defect in cellular response to chemotaxis B) Failure to exhibit increased anaerobic metablolism during phagocytosis C) Mild to marked defect in bactericidal ability of neutrophils D) Defective leukocyte locomotion

D) Defective leukocyte locomotion

The principal type of leukocyte in the process of phagocytosis is the: A) Eosinophil B) Basophil C) Monocyte D) Neutrophil

D) Neutrophil

The host defense function(s) of monocytes-macrophages include(s): A) Antigen presentation B) Phagocytosis C) Secretion of antibody by plasma cells D) Phagocytosis

D) Phagocytosis

Match the appropriate monocyte-macrophage abnormality with its respective condition: _______ Defective release of macrophage-activating factors A) Wiskott-Aldrich syndrome B) Burns or diabetes C) Systemic lupus erythematosus D) Corticosteroid therapy E) Intracellular infections

E) Intracellular infections

The surface MHC class II gene product is important in: A) Antigen recognition by T lymphocytes B) Antigen recognition by B lymphocytes C) Synthesis of antibody by plasma cells D) Phagocytosis

A) Antigen recognition by T lymphocytes

Arrange the sites of blood cell development (hematopoiesis) in the embryo and fetus in the correct sequence of development: ______ Predominant site from 2 to 5 months of fetal life A) Liver and spleen B) Yolk sac C) Bone marrow

A) Liver and spleen

Match each disorder or deficiency to its characteristics: ______ Chediak-Higashi anomaly (syndrome) A) Marked defect in cellular response to chemotaxis B) Failure to exhibit increased anaerobic metablolism during phagocytosis C) Mild to marked defect in bactericidal ability of neutrophils D) Defective leukocyte locomotion

A) Marked defect in cellular response to chemotaxis

Chronic granulomatous disease represents a defect of: A) Oxidative Metabolism B) Abnormal granulation of neutrophils C) Diapedesis D) Chemotaxis

A) Oxidative Metabolism

Match the following cell types to their respective functions. (An answer can be used more than once.) ______ Mononuclear monocytes-macrophages A) Primary phagocytic cells B) Antibody-synthesizing cells C) Recognition of foreign antigen and production of antibody

A) Primary phagocytic cells

Match the following cell types to their respective functions. (An answer can be used more than once.) ______ Polymorphonuclear neutrophil (PMN) leukocytes A) Primary phagocytic cells B) Antibody-synthesizing cells C) Recognition of foreign antigen and production of antibody

A) Primary phagocytic cells

Match each disorder or deficiency to its characteristics: ______ Chronic granulomatosus disease A) Marked defect in cellular response to chemotaxis B) Failure to exhibit increased anaerobic metablolism during phagocytosis C) Mild to marked defect in bactericidal ability of neutrophils D) Defective leukocyte locomotion

B) Failure to exhibit increased anaerobic metablolism during phagocytosis

Match the following cell types to their respective functions. (An answer can be used more than once.) ______ Plasma Cells A) Primary phagocytic cells B) Antibody-synthesizing cells C) Recognition of foreign antigen and production of antibody

B) Antibody-synthesizing cells

Match the appropriate monocyte-macrophage abnormality with its respective condition: _______ Depressed migration A) Wiskott-Aldrich syndrome B) Burns or diabetes C) Systemic lupus erythematosus D) Corticosteroid therapy E) Intracellular infections

B) Burns or diabetes