Chapter 9 D. Definition to Term

Systemic lupus erythematosus SLE

An inflammatory connective tissue disease, chronic in nature, in which immune complexes are from the reaction of SLE autoantibodies and their corresponding antigens.

sickle cell anemia

A chronic hereditary form of hemolytic anemia in which the RBCs become shaped like crescents in the presence of low oxygen tension.

hemolytic anemia

A form of anemia characterized by the extreme reduction in circulating RBCs due to their destruction.

pernicious anemia

A form of anemia resulting from a deficiency of mature RBC's and the formation and circulation of megaloblasts, large nucleated, immature, poorly functioning RBCs, with marked poikilocytosis, RBC shape variation, and anisocytosis, RBC size variation.

Acquired immunodeficiency syndrome AIDS

A syndrome present with immunodeficiency in the last or final phase of a human immunodeficiency virus HIV infection that primarily damages helper T cell lymphocytes with CD4 receptors.

hemophilia

A term used to define different hereditary inadequacies of coagulation factors, which result in prolonged bleeding times.

aplastic anemia

Also called "bone marrow depression anemia," it is a form of anemia characterized by pancytopenia- an inadequacy of all the formed blood elements; RBCs, WBCs, and platelets.

polycythemia vera

An abnormal proliferation of RBCs, granulocytes, and thrombocytes leading to an increase in blood volume and viscosity, thickness.

purpura

Collection of blood beneath the skin in the form of pinpoint hemorrhages appearing as red-purple skin discolorations.

leukemia ALL, AML, CML

Excessive uncontrolled increase of immature WBCs in the blood eventually leading to infection, anemia and thrombocytopenia.