Chapter 9

A condition in which there is an extreme loss of white blood cells is known as chronic anemia. True False

False

A conventional laminar flow hood may be used as biological safety cabinet. True False

False

BSCs should only be cleaned if a spill occurs. True False

False

Handling hazardous or cytotoxic agents is the same as any IV admixture. True False

False

Transporting cytotoxic drugs through a pneumatic system is allowed as long as there is a hazardous drug warning label on the outside of the bag. True False

False

All personnel that handle hazardous drugs must be aware of the risks and adhere to strict guidelines during exposure. True False

True

Chemotherapy agents are used to either destroy cancer cells or control their growth with minimal effect to normal cells. True False

True

Cytotoxic agents are antineoplastic agents that kill diving cells. True False

True

The air in a BSC should be 100% vented to the outside air through HEPA filtration. True False

True

Tubing should be primed before adding cytotoxic agents to avoid unnecessary exposure for everyone involved. True False

True

Sampling of surface areas for facilities that prepare large amount of hazardous drugs should occur at least every a. 6 months. b. 12 months. c. 24 months. d. 18 months.

a. 6 months.

A closed container that should be used to expel excess drug is called a(n) a. EEC. b. CSP. c. PPE. d. CSTD.

a. EEC.

To contain potential spillage, the final chemo product should be prepared as follows for delivery to patient area. a. Sealed in a plastic bag with a chemo label b. Placed in a sealed bag c. Made in a syringe with protective cap only d. None of the above

a. Sealed in a plastic bag with a chemo label

The chemotherapeutic agents that attach side chains to the proteins within the cancer cells and interfere with their functions are called a. alkylating agents. b. hormone agents. c. miscellaneous agents. d. antimetabolic agents.

a. alkylating agents.

All of the following are common adverse side effects associated with chemotherapy EXCEPT a. insomnia. b. loss of hair. c. mouth sores. d. vomiting.

a. insomnia.

Regarding hazardous drugs, USP 797 states: a. "Conduct regular training reviews with all potentially exposed workers in workplaces where hazardous drugs are used." b. "Personnel who compound hazardous drugs should be fully trained in the storage, handling, and disposal of these drugs." c. Both a and b d. None of the above

b. "Personnel who compound hazardous drugs should be fully trained in the storage, handling, and disposal of these drugs."

Chemotherapy agents should be prepared in a(n) a. LAFW. b. CACI. c. both a and b. d. none of the above.

b. CACI.

Which of the following statements are true about chemotherapy agents? a. Chemotherapy agents are different from antineoplastic agents. b. Chemotherapy agents damage healthy cells. c. Chemotherapy agents are only given to elderly patients. d. Chemotherapy agents have very few risks.

b. Chemotherapy agents damage healthy cells.

Cancer drugs are also called a. neoplastic agents. b. antineoplastic agents. c. antimalignant agents. d. none of the above.

b. antineoplastic agents.

The chemotherapeutic agent that interferes with DNA or RNA synthesis is a(n) a. antimetabolic. b. antitumor antibiotic. c. immunomodulating agent. d. enzyme inhibitor.

b. antitumor antibiotic.

When adding diluent to a vial of hazardous drug, the technician should inject a. slightly more air into the vial than required to maintain "negative" pressure. b. slightly less air into the vial than required to maintain "negative" pressure. c. slightly more air into the vial than required to maintain "positive" pressure. d. slightly less air into the vial than required to maintain "positive" pressure.

b. slightly less air into the vial than required to maintain "negative" pressure.

The air in a biological safety cabinet is taken in at a. the bottom, passes through the HEPA filter, and is then blown upward. b. the top, passes through the HEPA filter, and then is blown downward. c. the top, passes through the HEPA filter, and then is blown across the work surface d. the front, passes through the HEPA filter, and then is blown across the work area.

b. the top, passes through the HEPA filter, and then is blown downward.

If a spill occurs and there is contact with the eyes, they should be rinsed for a. 1 to 2 minutes. b. 2 to 3 minutes. c. 3 to 5 minutes. d. 2 to 4 minutes.

c. 3 to 5 minutes.

The chemotherapeutic agent that inhibit the growth of cells is a(n) a. antimetabolic. b. antitumor antibiotic. c. immunomodulating agent. d. enzyme inhibitor.

c. immunomodulating agent.

When wearing double gloves, the technician should a. tuck both gloves under the gown sleeve. b. tuck the gown sleeve under both gloves. c. tuck the inner glove under the gown sleeve and the outer glove over. d. replace both gloves immediately if the outer glove is contaminated.

c. tuck the inner glove under the gown sleeve and the outer glove over.

The BSC should be a. turned off when it is not being used. b. turned on only during business hours. c. turned on 24 hours a day. d. used at least once a day.

c. turned on 24 hours a day.

A needleless device that is used to allow the air to escape through the closed system rather than in the air is referred to as a. EEC. b. CSP. c. PPE. d. CSTD.

d. CSTD.

All of the following are commonly used to prepare chemotherapy drugs EXCEPT a. gloves. b. gown. c. absorbent pads. d. all of the above.

d. all of the above.

Testing of specific techniques should be given at least a. quarterly. b. biannually. c. every 6 months. d. annually.

d. annually.

Mitotic inhibitors interfere with a. cell metabolism. b. cell function. c. cell growth. d. cell division.

d. cell division.