Edwards & Patau syndrome

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Clinical features of Edwards syndrome?

1) Low birth weight 2) Prominent occiput 3) Small mouth & chin 4) Short sternum 5) Flexed overlapping fingers 6) 'Rocker-bottom' feet 7) Cardia and renal malformations

Clinical features of Patau syndrome

1- Microphthalmia 2- Microcephaly 3- Severe intellectual disability 4- Cleft lip and palate 5- Polydactyly 6- Cardiac and renal defects 7- Umbilical hernias 8- Cutis aplasia

What is Patau syndrome?

Trisomy of chromosome 13

What is Edwards syndrome?

Trisomy of chromosome 18


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