MORPHINE SULFATE
what are the trade names of morphine sulfate?
- MS Contin -Roxanol
what are the side effects of morphine sulfate?
-N &V -constipation, drowsiness -dizziness -sedation, confusion, urinary retention, rash, blurred vision, bradycardia, flushing, euphoria, pruritus
what is the mode of action for morphine sulfate?
-depression of the CNS -depression of pain impulses by binding with the opiate receptor in the CNS
what are the contraindications of morphine sulfate?
-hypersensitivity -CNS or Respiratory depression -status asthmaticus -increased intracranial pressure -shock -alcoholism -ileus -hypovolemia CAUTION - respiratory, renal or hepatic disease, urinary retention, sleep apnea, older adults or very young.
what are the adverse effects of morphine sulfate?
-hypotension -uriticaria -seizure -ileus -respiratory depression -increase intracranial pressure
what are the drug interactions?
-increase effect of alcohol -sedative hypnotic -antipsychotic drug -muscle relaxant
nursing intervention
check bowel sounds for decreased peristalsis---> indicate constipation
nursing intervention
check for pinpoint pupils --> indicate morphine overdose
nursing intervention
give morphine before pain reaches its peak
nursing intervention
have nalaxone available as an antidote to reverse respiratory depression if morphine overdose
what are the lab interactions?
increase AST, ALT
nursing intervention
look at urine output for urinary retention
nursing intervention
look at vital signs to find any respiratory changes
nursing intervention
no alcohol or CNS depressant with any opioid analgesic like morphine---> respiratory distress
what is the drug class of morphine sulfate?
opioid
nursing intervention
report dizziness---> can be from orthostatic hypotension
what are the therapeutic effects of morphine sulfate?
to relieve severe pain
