MORPHINE SULFATE

what are the trade names of morphine sulfate?

- MS Contin -Roxanol

what are the side effects of morphine sulfate?

-N &V -constipation, drowsiness -dizziness -sedation, confusion, urinary retention, rash, blurred vision, bradycardia, flushing, euphoria, pruritus

what is the mode of action for morphine sulfate?

-depression of the CNS -depression of pain impulses by binding with the opiate receptor in the CNS

what are the contraindications of morphine sulfate?

-hypersensitivity -CNS or Respiratory depression -status asthmaticus -increased intracranial pressure -shock -alcoholism -ileus -hypovolemia CAUTION - respiratory, renal or hepatic disease, urinary retention, sleep apnea, older adults or very young.

what are the adverse effects of morphine sulfate?

-hypotension -uriticaria -seizure -ileus -respiratory depression -increase intracranial pressure

what are the drug interactions?

-increase effect of alcohol -sedative hypnotic -antipsychotic drug -muscle relaxant

nursing intervention

check bowel sounds for decreased peristalsis---> indicate constipation

nursing intervention

check for pinpoint pupils --> indicate morphine overdose

nursing intervention

give morphine before pain reaches its peak

nursing intervention

have nalaxone available as an antidote to reverse respiratory depression if morphine overdose

what are the lab interactions?

increase AST, ALT

nursing intervention

look at urine output for urinary retention

nursing intervention

look at vital signs to find any respiratory changes

nursing intervention

no alcohol or CNS depressant with any opioid analgesic like morphine---> respiratory distress

what is the drug class of morphine sulfate?

opioid

nursing intervention

report dizziness---> can be from orthostatic hypotension

what are the therapeutic effects of morphine sulfate?

to relieve severe pain