Patho Quiz 2

Risk factors for atherosclerosis include

hyperlipidemia (condition in of high levels of fat particles (lipids) in the blood). Such as cholesterol or triglycerides

A deficiency of von Willebrand factor impairs

Platelet adhesion to injured tissue

The relationship of blood flow (Q), resistance (R), and pressure (P) in a vessel can be expressed by which equation?

Q = P/R

Which vessel normally demonstrates the most rapid blood flow?

Vena cava

Hemophilia B is also known as Christmas disease.

True

Activation of the extrinsic pathway of coagulation is initiated by

tissue thromboplastin

A child with a history of recent strep throat infection develops glomerulonephritis. This is most likely a type _____ hypersensitivity reaction.

type 3 hypersensitivity

Tissues are able to autoregulate their rate of blood flow by controlling

vascular resistance

A newborn has melena, bleeding from the umbilicus, and hematuria. The newborn most likely experiencing

vitamin K deficiency bleeding

Clot retraction occurs

when the components of the fibrin clot are compressed or contracted to form a clot

An important mediator of a type I hypersensitivity reaction is

histamine

A patient presents to the physician's office with pinpoint hemorrhages on the skin. The patient is most likely between the ages of _____ years.

4 & 7

Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions.

False, Type 1 hypersensitivity

The conversion of plasminogen to plasmin results in

Fibrinolysis the process of clot dissolution

A 5-year-old patient's parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk as a result of pain. The child's most likely diagnosis is

Acute lymphoid leukemia ( All)

Patients with immunodeficiency disorders are usually first identified because they

Because they develop recurrent infections

Velocity of blood flow is measured

Centimeters per second

Widespread activation of the clotting cascade secondary to massive trauma is called

Disseminated intravascular coagulation (DIC)

Treatment for hemophilia A includes

Factor VIII replacement

The effects of histamine release include

Increased vascular permeability

intrinsic factor

a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining.

A commonly ingested substance associated with prolongation of the bleeding time is

aspirin

Blood flow throughout the periphery is regulated by

autonomic nervous system

Most carbon dioxide is transported in the bloodstream as

bicarbonate ion

When systemic vascular resistance is decreased, blood flow

decreases

Severe combined immunodeficiency (SCID) syndrome is an example of a(n)

deficient immune response

Patients who experience anemic episodes when exposed to certain drugs most likely have

glucose-6-phosphate dehydrogenase deficiency

The patient is a 12-year-old boy diagnosed with acute lymphoid leukemia (ALL). As part of treatment, the patient must undergo several weeks of chemotherapy. The most serious complication of chemotherapy is

infection

Disseminated intravascular coagulation may be treated with heparin therapy to

inhibit clotting factor consumption

Pernicious anemia is caused by a lack of

intrinsic factor

The activated partial thromboplastin time (aPTT) is a measure of the integrity of

intrinsic pathway

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia?

iron deficiency

Thalassemia may be confused with iron-deficiency anemia, because they are both

microcytic

RhoGAM (an Rh antibody) would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

negative, negative, positive

Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are

obstruction of the superior vena cava and compression of the spinal cord.

The strength of the bond between oxygen and hemoglobin is known as the

oxygen-hemoglobin affinity

A serious complication of deep vein thrombosis is

pulmonary embolus

Transfusion reactions involve RBC destruction caused by

recipient antibodies

The movement of blood through the vascular system is opposed by the force of

resistance

The most common primary immune deficiency that affects only B cells is

selective IgA. When you lack or don't have enough immunoglobulin A (IgA), a protein that fights infection (antibody).

Which disorder is associated with a type III hypersensitivity mechanism of injury?

systemic lupus erythematosus