Public Health Small Pox
The origin of smallpox is uncertain, but it is believed to have originated in either ----- or in ----- about 10 thousand years BC
Africa , China
At one time smallpox was a significant disease in every country throughout the world except -----
Australia
The ----- enabled vaccinators to bring the jet
"Ped-O-Jet"
----- were now nearly 100 percent and the procedure could be done quickly and easily
"Vaccine takes"
Dr. Bill Foege recommended the successful ----- for Nigeria.
"ring immunity plan"
The hydraulic-powered jet injector could do over -----
1,000 vaccinations in an hour.
Four species of the genus Orthopoxvirus cause infection in humans:
1. variola virus (major and minor) 2. vaccinia virus, 3. cowpox virus, and 4. monkeypox virus.
in 1967, ----- cases were still occurring annually in more than 30 endemic countries
10 - 15 million
The first recorded smallpox epidemic was in ----- during the Egyptian-Hittite war.
1350 BC
By ----- routine immunization had eliminated smallpox in the United States
1958
Routine small pox vaccination among american public stopped in
1972
In 1967, more than ----- people died of smallpox
2 million
The United States saves the total of all its contributions every ----- days because -----
26, it does not have to vaccinate or treat the disease
----- or inventions led to the ability for the World to eradicate smallpox
3 discoveries
depending upon the type, Smallpox can have an infectivity rate of up to -----
70%
NUMBER THREE: -----
BIFURCATED NEEDLE
The last case of Variola major occurred in -----
Bangladesh in 1975
In 1966 ----- was chosen to head up the successful WHO Global Smallpox Eradication Campaign
D.A. Henderson, M.D.
----- directed the CDCs Smallpox Eradication Program from 1963-1970.
Donald Millar, M.D.
----- won the Presidential Medal of Freedom - the highest civilian award in the U.S.
Dr. Henderson
the English country doctor ----- noticed that dairymaids, who had contracted cowpox seemed to be protected from smallpox.
Edward Jenner
NUMBER ONE: -----
FREEZE-DRIED VACCINE
On January 1, 1967, the World Health Organization (WHO) launched the -----
Intensified Smallpox Eradication Program
NUMBER TWO: -----
JET INJECTOR
in ----- the World Health Organization (WHO) declared the global eradication of smallpox
May 1980
variola virus is a large ----- of the family Poxviridae, subfamily Chordopoxvirinae.
Orthopoxvirus
These long-haired, laid-back, energetic ----- volunteers were the backbone of the eradication effort.
Peace Corp
Largest and most complex of viruses
Poxviruses
double-stranded DNA
Poxviruses
The earliest evidence of smallpox is found on the mummy of Egyptian Pharaoh -----
Ramses V.
----- the recipient of the 25th millionth vaccination.
Rebecca Ansah Asamoah
The last documented case of Variola minor (on Earth) occurred in -----
Somalia in 1977 (Ali Maalin)
The last U.S. case of Variola occurred in
Texas in 1949
in the 20th century, Vaccine (Vaccinia) is being harvested from -----
calf Lymph.
Jenner theorized that -----
cowpox provided immunity from Smallpox
Poxviruses have a complex internal structure with a large ------genome enclosed within a "core" that is flanked by 2 "lateral bodies".
double-stranded DNA
William (Bill) Foege, M.D. devised the global strategy that led to the -----
eradication of smallpox
The smallpox virus can live only in ----- not in animals or insects.
humans
Smallpox is the only -----
major human disease to have been eradicated.
The vaccine was -----
mass produced.
Smallpox is an "infectious" disease caused by -----
variola virus
The name "variola" was chosen as a derivative of the Latin ----- meaning ----- or ----- meaning -----
varius-"spotted", varus-"pimple"
Poxviruses are -----
very large rectangular viruses the size of small bacteria.
Director of the Centers for Disease Control and Prevention (CDC) from 1977-1983.
William (Bill) Foege, M.D.
----- the Surgeon General of the United States
William Stewart
