Public Health Small Pox

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The origin of smallpox is uncertain, but it is believed to have originated in either ----- or in ----- about 10 thousand years BC

Africa , China

At one time smallpox was a significant disease in every country throughout the world except -----

Australia

The ----- enabled vaccinators to bring the jet

"Ped-O-Jet"

----- were now nearly 100 percent and the procedure could be done quickly and easily

"Vaccine takes"

Dr. Bill Foege recommended the successful ----- for Nigeria.

"ring immunity plan"

The hydraulic-powered jet injector could do over -----

1,000 vaccinations in an hour.

Four species of the genus Orthopoxvirus cause infection in humans:

1. variola virus (major and minor) 2. vaccinia virus, 3. cowpox virus, and 4. monkeypox virus.

in 1967, ----- cases were still occurring annually in more than 30 endemic countries

10 - 15 million

The first recorded smallpox epidemic was in ----- during the Egyptian-Hittite war.

1350 BC

By ----- routine immunization had eliminated smallpox in the United States

1958

Routine small pox vaccination among american public stopped in

1972

In 1967, more than ----- people died of smallpox

2 million

The United States saves the total of all its contributions every ----- days because -----

26, it does not have to vaccinate or treat the disease

----- or inventions led to the ability for the World to eradicate smallpox

3 discoveries

depending upon the type, Smallpox can have an infectivity rate of up to -----

70%

NUMBER THREE: -----

BIFURCATED NEEDLE

The last case of Variola major occurred in -----

Bangladesh in 1975

In 1966 ----- was chosen to head up the successful WHO Global Smallpox Eradication Campaign

D.A. Henderson, M.D.

----- directed the CDCs Smallpox Eradication Program from 1963-1970.

Donald Millar, M.D.

----- won the Presidential Medal of Freedom - the highest civilian award in the U.S.

Dr. Henderson

the English country doctor ----- noticed that dairymaids, who had contracted cowpox seemed to be protected from smallpox.

Edward Jenner

NUMBER ONE: -----

FREEZE-DRIED VACCINE

On January 1, 1967, the World Health Organization (WHO) launched the -----

Intensified Smallpox Eradication Program

NUMBER TWO: -----

JET INJECTOR

in ----- the World Health Organization (WHO) declared the global eradication of smallpox

May 1980

variola virus is a large ----- of the family Poxviridae, subfamily Chordopoxvirinae.

Orthopoxvirus

These long-haired, laid-back, energetic ----- volunteers were the backbone of the eradication effort.

Peace Corp

Largest and most complex of viruses

Poxviruses

double-stranded DNA

Poxviruses

The earliest evidence of smallpox is found on the mummy of Egyptian Pharaoh -----

Ramses V.

----- the recipient of the 25th millionth vaccination.

Rebecca Ansah Asamoah

The last documented case of Variola minor (on Earth) occurred in -----

Somalia in 1977 (Ali Maalin)

The last U.S. case of Variola occurred in

Texas in 1949

in the 20th century, Vaccine (Vaccinia) is being harvested from -----

calf Lymph.

Jenner theorized that -----

cowpox provided immunity from Smallpox

Poxviruses have a complex internal structure with a large ------genome enclosed within a "core" that is flanked by 2 "lateral bodies".

double-stranded DNA

William (Bill) Foege, M.D. devised the global strategy that led to the -----

eradication of smallpox

The smallpox virus can live only in ----- not in animals or insects.

humans

Smallpox is the only -----

major human disease to have been eradicated.

The vaccine was -----

mass produced.

Smallpox is an "infectious" disease caused by -----

variola virus

The name "variola" was chosen as a derivative of the Latin ----- meaning ----- or ----- meaning -----

varius-"spotted", varus-"pimple"

Poxviruses are -----

very large rectangular viruses the size of small bacteria.

Director of the Centers for Disease Control and Prevention (CDC) from 1977-1983.

William (Bill) Foege, M.D.

----- the Surgeon General of the United States

William Stewart


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