UA Ch2 and Ch9

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The presence of argentaffin cell tumors can be detected by the presence in the urine of:

5-HIAA

Lamellar bodies are analyzed by:

ADVIA 2120i

A positive Guthrie test is interpreted by observing:

Bacterial growth occurs around the positive control disc and the patient disc

Which of the following is a complete urinalysis automated urinalysis system?

Clinitek AUWi Pro system

The 2,4-dinitrophenylhydrazine reaction is the confirmatory test for maple syrup urine disease

False

Which of the following is not an advantage of automated microscopy

High Variation of results

Which of the following urine sediment particles cannot be autovalidated but will be flagged and must be reviewed by laboratory personnel?

RTEs

Patients who have unusually fair complexions can be indicative for phenylketonuria because

Tyrosine is not available for conversion to melanin

Which automated urine particle counter combines urine flow cytometry with digital image analysis?

UN-2000

A major advantage of a fully automated analyzer versus a semi-automated analyzer is:

Walk-away capability

Which of the automated body fluid analyzers does not need to dilute or pretreat body fluids before analysis?

XN series

The presence of porphobilinogen in the urine can be suspected when:

acidic urine turns a port wine color after standing

A positive urine Clinitest reaction can be seen in patients with

alkaptonuria

Accumulation of large amounts of homogentisic acid in the urine is the result of which of the following disorders?

alkaptonuria

the advantages of an automated urine microscopy analyzer over manual microscopy includes:

all of the above

Which of the following fluids are not FDA cleared to be evaluated using XN-Series?

amniotic

The finding of increased amounts of the serotonin degradation product 5-HIAA in the urine indicates:

argentaffin cell tumors

The finding of persistent ketonuria in a newborn is:

associated with methylmalonic aciduria

Which of the following urine elements if flagged by automated microscopy would need to be confirmed by a manual examination?

crystals

Patients who produce kidney stones at an early age should be tested for the presence of:

cystinuria

A false-positive test for 5-HIAA may result if the patient:

does not recieve appropriate diet instructions

The Fuchs-Rosenthal, Nageotte, and Neubauer hemocytometers are calibrated the same for manual body fluid counting.

false

What two technologies are used for urine sediment analysis?

flow cytometry and digital imaging

A method for performing automated urine sediment analysis is

fluorescent light

GALT deficiency is a disorder affecting the metabolism of:

galactose

All of the following disorders are caused by defects in the phenylalanine-tyrosine pathway except:

hartnup disease

Analysis of urine from an infant whose mother reported a blue staining on the diapers showed increased levels of indican and a generalized aminoaciduria. On the basis of these findings, the infant was diagnosed as having:

hartnup disease

Phenylketonuria is caused by:

lack of the enzyme phenylalanine hydroxylase

Which of the following cells need further intervention when analyzed by automated body fluid instruments?

malignant cells

A routine urinalysis is performed on a specimen that has turned dark after standing in the laboratory. The urine is acidic and has negative chemical tests except for the appearance of a red color on the ketone area of the reagent strip. One should suspect

melanuria

false-positive reaction for urinary ketones could be present in patients who have

melanuria

Automated urine particle digital imaging does not measure:

particle density

All of the following porphyrin compounds can be found in urine except:

protoporphyrin

The principle commonly used to measure the concentration of a particular analyte in the chemical examination of urine is

reflactance photometry

In automated urinalysis, the specific gravity is measured by

refractometry

To differentiate between cystinuria and homocystinuria, the urine should be tested with:

silver nitroprusside

all of the following are true concerning fully automated urine chemistry analyzers except:

the reagent strip is dipped into the well mixed urine

Reflectance photometry uses the principle that light reflection from the reagent test pads decreases in proportion to the intensity of the color produced.

true

Abnormal amounts of indigo blue in the urine are indicative of a defect in the metabolism of:

tryptophan

What is a disadvantage of counting body fluid cells using an automated instrument versus a Neubauer hemocytometer?

unable to count low WBC numbers and malignant cells


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