Virus
phages 2 reproductive mechanisms
- The lytic cycle - The lysogenic cycle
Which of the following events stimulates the production of viral particles in a host cell?
Activation of the host cell by cytokines, growth factors, or antigens. Activation of the host immune cell by cytokines, growth factors, or antigens causes viral DNA to be transcribed at high rates in preparation for viral production
True
An animal virus with an envelope uses it to enter the host cell The envelope is made up from the plasma membrane
Virus
An infectious particle consisting of nucleic acid enclosed in a protein coat
Why do RNA viruses tend to have unusually high rates of mutation?
Replication of their genomes does not involve proofreading.
viral envelope
Surround the caspids of influenza viruses and many other viruses found in animals, derived from the host cell's membrane, contain a combination of viral and host cell molecules
A researcher lyses a cell that contains nucleic acid molecules and capsomeres of tobacco mosaic virus (TMV). The cell contents are left in a covered test tube overnight. The next day this mixture is sprayed on tobacco plants. Which of the following would be expected to occur?
The plants would develop the typical symptoms of TMV infection.
Which of the following statements correctly describes one difference between vertical and horizontal transmission of plant viruses
Vertical transmission is transmission of a virus from a parent plant to its progeny, and horizontal transmission is one plant spreading the virus to another plant
Most molecular biologists think that viruses originated from naked bits of cellular nucleic acid. Which of the following observations supports this theory?
Viral genomes are usually similar to the genome of the host cell.
Which of the following statements accurately describes plant virus infections?
They are spread via the plasmodesmata
lytic cycle
a phage reproductive cycle that culminates in the death of the host cell - produced new phages and lyses the host's cell Wall,releasing the progeny viruses - A phage reproduces only by the lytic cycle is called a virulent phage - A bacteria have defenses against phages including restriction enzymes that recognize and cut up certain phage DNA
Which of the following processes can be effective in preventing the onset of viral infection in humans
getting vaccinated
lysogenic cycle
replicates the phage genome without destroying the host - The viral DNA molecule is incorporated into the host cell's molecule -This integrated viral DNA is known as a prophage -Every time the host divides, it copies the phage DNA and passes the copies the phage DNA and passes the copies to daughter cells
The lytic cycle of bacteriophage infection ends with the
rupture of the bacterium
Which of the following statements correctly describes one characteristic of the lytic cycle of viral replication
A large number of phages are released at a time.
Bacteriaphage
Called phages Are viruses that infect bacteria
CRISPR-CAS
Consists of clustered regularly inter spaced short palindromic repeats and nucleares enzyme called CAS, CRISPR associated proteins
True
Each virus has a host range, a limited number that it can infect
The human immunodeficiency virus (HIV) uses reverse transcriptase to make double-stranded RNA copies of its DNA genome
False A retrovirus such as HIV has an RNA genome and uses reverse transcriptase to make double-stranded DNA copies of the genome, which can then be integrated into the host cell's genome
How does HIV cause disease
HIV kills cells that defend the body against disease.
Which enzyme inserts viral DNA into the host's chromosomal DNA
Integrase inserts viral DNA into the host's chromosomal DNA.
What happens first when a phage infects a bacterial cell and is going to enter a lysogenic cycle
Linear DNA circularizes.
Which replicative cycle describes a virus that can integrate its genome into the host cell's genome
Lysogenic -A lysogenic virus can integrate its genome into the host cell's genome and be duplicated by the host cell's replication machinery.
Virus Genomes
May consisting of either - Double or single-stranded DNA - Double or single-stranded RNA
True
Phage DNA is often identified as foreign and cut up as restriction enzymes
Temperate Changes
Phages that use both lytic and lysogenic cycles
Caspid
The protein shell that encloses that viral genome Built from protein subunits capsomeres
True
The viral envelope mediates entry into the cell, the capsid enters into the nuclear membrane, and the genome is all that enters the nucleus.
How does HIV bind to a host cell
The viral envelope proteins interact with CD4 and a co-receptor on the cell membrane.
How do enveloped viruses differ from nonenveloped viruses
They have a membrane-like outer covering.
Which of the following statements correctly describes the best predictor of how much damage a virus causes
ability of the infected cell to undergo normal cell division
Antiviral drugs that have become useful are usually associated with which of the following properties
interference with viral replication
HIV uses which of the following processes to synthesize a DNA strand using its RNA genome as a template
reverse transcription Retroviruses are equipped with an enzyme called reverse transcriptase, which makes a DNA copy of an RNA template, providing information flow from RNA to DNA.
As a result of the lytic cycle
the host cell's DNA is destroyed
Retroviruses
use reverse transcriptase to copy their RNA genome into DNA
In the lysogenic cycle
viral DNA is replicated along with host DNA Viral DNA, incorporated into host DNA as a prophage, is replicated along with host DNA