Xo: cholesterol and lipds

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Acetyl-CoA carboxylase enzyme of fatty acid synthesis function?

function is to provide malonyl coA substrate for biosynthesis of fatty acids

Rate limiting step of cholesterol biosynthesis?

HMG CoA reductase

How do statin drugs work?

HMG-CoA reductase inhibitors

LDL receptor is?

APOB-100 apolipoprotein B

De novo cholesterol production involves everything except?

Oxygen (needs ATP, NADPH, acetyl CoA and malonyl CoA)

Triglyceride is carried from the liver to organs by

VLDL

What are chylomicrons function?

carry triglycerides from intestines to liver

how do animal cells primary use cholesterol?

cell membrane

what is the most abundant non-phospholipd substance in cell mb?

cholesterol

how do fats circulate in the blood?

chylomicrons > liver > VLDL > blood > tissue > LDL > HDL

hyperlipidemia definition?

fat in blood

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