Xo: cholesterol and lipds
Acetyl-CoA carboxylase enzyme of fatty acid synthesis function?
function is to provide malonyl coA substrate for biosynthesis of fatty acids
Rate limiting step of cholesterol biosynthesis?
HMG CoA reductase
How do statin drugs work?
HMG-CoA reductase inhibitors
LDL receptor is?
APOB-100 apolipoprotein B
De novo cholesterol production involves everything except?
Oxygen (needs ATP, NADPH, acetyl CoA and malonyl CoA)
Triglyceride is carried from the liver to organs by
VLDL
What are chylomicrons function?
carry triglycerides from intestines to liver
how do animal cells primary use cholesterol?
cell membrane
what is the most abundant non-phospholipd substance in cell mb?
cholesterol
how do fats circulate in the blood?
chylomicrons > liver > VLDL > blood > tissue > LDL > HDL
hyperlipidemia definition?
fat in blood