ADHD
What is the estimated average cost of ADHD in the US?
$32 billion a year about $11,000 per child
What types of evidence is there that points to a genetic influence as a key causal factor in ADHD?
- ADHD runs in families - adoption studies - twin studies - specific gene studies
what was the major finding of the MTA
- after 14 months of active treatment all groups showed reductions in ADHD symptoms overtime - combining behavioral treatments with medication resulted in no additional benefits for the core symptoms, but did provide some benefits for non-ADHD symptoms and other outcomes related to positive functioning - combined treatment was the best followed by stimulant medications, then behavior therapy, and finally community treatment - once treatment is stopped the benefits decrease or cease
What are the core symptoms/features of ADHD?
- age-inappropriate inattention, and/or hyperactivity/impulsivity - problems with sustained attention/focusing - problems controlling one's behaviour - absence of care when performing a cognitive act
to diagnose ADHD using the DSM the behaviors must also?
- appear before age 7 - occur more often and with greater severity than in other children the same age and sex - continue for more than 6 months - occur across several settings (i.e., home and school) - produce significant impairments in the child's social or academic performance
what is ADHD a significant risk factor for?
- cigarette smoking - substance abuse - risky sexual behaviors
what neurobiological factors have been presented (an analysis between children with and without ADHD)?
- differences on psychophysiological measures suggesting diminished arousal or arousability - differences on measures of brain activity during vigilance tests, suggesting under-responsiveness to stimuli and deficits in response inhibition - differences in blood flow to the prefrontal regions of the brain and the pathways connecting these regions to the limbic system, suggesting decreased blood flow to these regions
according to lecture what constitutes impulsive behaviors?
- difficulty waiting ones turn - inability to resist immediate gratification
according to lecture what constitutes hyperactive behavior
- excessively energetic behavior that is not goal directed - constant fidgeting, difficulty staying seated, constantly moving, excessive talking
what are the typical speech and language problems children with ADHD have?
- excessively loud - frequent topic shifts - interruptions - an absence of clear connecting links in their conversation
How are family influences important with ADHD?
- family influences may lead to ADHD symptoms or to a greater severity of symptoms; parenting styles - family problems may result from interacting with a child who is impulsive and difficult to manage; the quality of parent/child relationship - family conflict is likely related to the presence, persistence, or later emergence of associated oppositional and conduct disorder symptoms
according to lecture what types of things fall under hyperactivity-impulsivity (HI)?
- inhibiting inappropriate behaviors and self regulation
what are the two major advantages summer treatment has over other interventions for ADHD?
- it maximizes opportunities to build effective peer relations in normal settings - it provides continuity to academic work to ensure gains made during the school year are not lost
what were the groups of the MTA (multimodalt treatment study of children with ADHD)?
- medication management - behavioral treatment - combined behavioral treatment and medication - routine community treatment
what are the types of impaired executive functions found in children with ADHD?
- organize, prioritize, ad activate - focus, shift and sustain attention - regulate alertness, effort and processing speed - manage frustration and modulate emotion - working memory and accessing recall - monitor and regulate action
what has recently been emphasized as the central impairments of ADHD?
- poor self-regulation - difficulty in inhibiting behavior - motivational deficits
what factors in pregnancy/birth/early development are seen as possible contributors to ADHD?
- pregnancy and birth complications - low birth weight - malnutrition - early neurological insult or trauma (i.e., head trauma) - diseases of infancy - tabacco -alcohol -drugs
according to lecture what types of things fall under inattention (IA)?
- problems with concentration; easily distracted - not listening - forgetful and disorganized - the child fails to complete assignments; difficulty persevering with tasks
what type of sleep disturbances are common in children with ADHD?
- resistance to going to bed - difficulty falling asleep - fewer total hours of sleep - involuntary sleep movements (i.e., teeth grinding/ restless sleep)
what are the common complaints of ADHD (inattention)?
- the child doesn't or won't listen, follow instructions, or finish chores or assignments
what is hard for children with impusivity?
- they have troubles stopping ongoing behaviour or to regulate their behavior in accordance with the demands of the situation or the wishes of others (i.e., blurting out answers whether right or wrong) - they have difficulties resisting immediate temptations and delaying gratification
what are the subtypes of ADHD?
1) ADHD-PI (primarily inattentive) 2) ADHD-HI (primarily hyperactive-impulsive) 3) ADHD-C (combination of PI and HI)
why has gene study for ADHD focused on dopamine?
1) because dopamine is a neurotransmitter used by the brain with a central role in psychomotor activity and reward-seeking 2) because brain structures implicated in ADHD are rich with dopamine innervation, and neuroimaging studies have found evidence for dopamine dysregulation 3) because primary medications that reduce ADHD symptoms act primarily by blocking the dopamine transporter (DAT1) -a receptor on the presynaptic neuron involved in the reuptake of dopamine- thereby increasing the availability of dopamine in synapses; DRD4 gene also seems to be involved
what are some of the limitations of the DSM-IV for ADHD?
1. categorical view (present or not present); research supports dimensionality 2. failure to adjust the number of required symptoms for either age or level of maturity (developmentally insensitive) 3. the required age of 7, as the age of onset, may be too young 4. symptoms must persist for 6 months may be misleading for very young children (too short) 5. symptoms must be demonstrated across at least two environments, may add equivocation (ambiguity) to the diagnosis (conflicting information; blending is better)
how many years does cortical development lag in children with ADHD?
2-3 years
what is the gender difference found in ADHD?
2-4% in girls and 6-9% in boys
about what percentage of children with ADHD experience depression of a mood disorder ?
20-30%
about what percentage of children with ADHD experience excessive anxiety?
25%
what percentage of children with ADHD develop CD?
30-50%
approx. how many children with ADHD also have a speech and language impairment?
30-60%
If a parent has ADHD what is the risk to their children?
60%
how many ADHD children often qualify for a learning disorder by late childhood?
80%
what percentage of children with ADHD does stimulants medications work?
80%
what is the lease common subtype of ADHD?
ADHD-HI
which of the subgroups for ADHD is the rarest?
ADHD-HI
what is the most common comorbid disorder for ADHD?
OOD/CD (oppositional defiant disorder/conduct disorder)
distractibility
a common term for a deficit in selective attention; children who have ADHD are much more likely to be distracted by stimuli that are highly salient and appealing
developmental coordination disorder (DCD)
a condition characterized by marked motor incoordination (i.e., clumsiness and delays in achieving motor milestones); overlaps with ADHD
subtype
a group of individuals with something in common - symptoms, etiology, problem severity, or likely outcome- something that makes them distinct from other groupings
What do children with ADHD-PI normally seen as having?
a learning disability, processing information slowly, find it hard to remember things, and display low academic achievement.
what must be done before a diagnosis of ADHD can be done?
a through assessment that includes a developmental history, parent and teacher reports, normed assessment instruments, and behavioral observations
what the first three symptoms, listed in the DSM-IV, that a child can have under inattention for at least 6 months so that they would qualify as having ADHD?
a) often fails to give close attention to details or makes careless mistakes in schoolwork, work, or other activities b) often has difficulty sustaining attention in tasks or play activities c) often does not seem to listen when spoken to directly
what the first three symptoms, listed in the DSM-IV, that a child can have under hyperactivity-impulsivity for at least 6 months so that they would qualify as having ADHD?
a) often fidgets with hands or feet or squirms in seat b) often leaves seat in classroom or in other situations in which remaining seated is expected c) often runs about or climbs excessively in situations in which it is inappropriate (in adolescents or adults, may be limited to feelings of subjective feelings of restlessness)
How many biological relatives of children with ADHD also have the disorder?
about 1/3
what is ADHD-HI and C associated with?
aggressiveness, defiance, peer rejection, school suspensions, placement in special ed. classes
positive illusory bias
an exaggeration of one's competence
alerting
an initial reaction to a stimulus, and involves the ability to prepare for what is about to happen
how are children with ADHD-PI normally rated?
as anxious and apprehensive, socially withdrawn, and may display mood disorders; about half of these children do not manifest the disorder until after age 7
why is it important to assess both symptoms and impairment functioning for ADHD?
because a child can display ADHD symptoms without necessarily displaying significant impairment, or a child may display subclinical levels of ADHD symptoms but still suffer significant maladjustment
Why doesn't increased efforts and stricter rules help children with ADHD?
because most children are already trying hard; they want to do well but are thwarted by their limited control
How was ADHD described in 1917-1926?
because of a flue epidemic children stared to show behavior problems (due to brain swelling) of irritability, impaired attention, and hyperactivity, so ADHD became know as brain injured child syndrome (associated with mental retardation)
why is it best to view hyperactivity-impusivity as one dimension?
because when children display one symptom they usually display the other as well
what is the difference in the brain of children with ADHD and of children who don't have ADHD?
children with ADHD have a smaller prefrontal cortex, and abnormalities in several regions of the basal ganglia; these children also have a delay in brain maturation (particularly in the prefrontal cortex)
what are the two categories of impusivity?
cognitive impulsivity and behavioral impusivity
what are the processes of executive functioning
cognitive processes, language processes, motor processes, and emotional processes
what are girls with ADHD versus girls without ADHD more likely to have?
conduct, mood, or anxiety disorders
what is conflict like at home (ADHD)?
conflict between children and mothers is sever during the preschool years and continues into childhood and adolescence; conflict with fathers is less frequent but still greater then other children and fathers
frontostriatal circuitry of the brain
consists of the prefrontal cortex and interconnected areas of gray matter located deep below the cerebral cortex, collectively known as the basal ganglia; these areas are associated with attention, executive functioning, delayed responding, and response organization
what the forth, fifth, and sixth symptoms, listed in the DSM-IV, that a child can have under inattention for at least 6 months so that they would qualify as having ADHD?
d) often does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace (not due to oppositional behaviour or failure to to understand instructions) e) often has difficulty organizing tasks and activities f) often avoids, dislikes, or is reluctant to engage in tasks that require sustained mental efforts (i.e., schoolwork)
what the forth, fifth, and sixth symptoms, listed in the DSM-IV, that a child can have under hyperactivity-impulsivity (hyperactivity) for at least 6 months so that they would qualify as having ADHD?
d) often has difficulty playing or engaging in leisure activities quietly e) is often "on the go" or often acts as if "driven by a motor" f) often talks excessively
attention-deficit/hyperactivity disorder (ADHD)
describes children who display persistent age-inappropriate symptoms of inattention, hyperactivity, and impassivity that are sufficient to cause impairment in major life activities
what are the two most effective stimulants in treating children with ADHD?
dextroamphetamine (dextrostat) and methylphenidate (ritalin)
hyperactive
displaying an unusually high level of energy and an inability to remain still or quiet
what is the focus of summer treatment programs?
enhancing present adjustment at home and future success at school by combining many of the primary and additional treatments in an intensive summer treatment
what have studies show of sleeping ADHD children?
even when asleep children with ADHD display more motor activity than other children
what cognitive defects do children with ADHD display?
executive function defects, intellectual deficts, impaired academic functioning, learning disorders, and distorted self-perception
what additional treatments is there for ADHD?
family counseling, support groups, and individual counseling
where have studies found brain abnormalities in children with ADHD?
findings have suggested abnormalities primarily in the frontostriatal circuitry of the brain
in children with ADHD those who experience the most severe social disability are at greatest risk for what?
for poor adolescent outcomes and other disorders such as depression and conduct disorder
what the seventh, eighth, and nineth symptoms, listed in the DSM-IV, that a child can have under hyperactivity-impulsivity (impulsivity) for at least 6 months so that they would qualify as having ADHD?
g) often blurts our answers before questions have been completed h) often has difficulty awaiting turn i) often interrupts or intrudes on others (i.e,. butts into conversations or games)
what the seventh, eighth, and nineth symptoms, listed in the DSM-IV, that a child can have under inattention for at least 6 months so that they would qualify as having ADHD?
g) often loses things necessary for tasks or activities (i.e., toys, school assignments, pencils, books,) h) is often easily distracted by extraneous stimuli i) is often forgetful in daily activities
behavioral impusivity
have difficulty inhibiting their response when the situation requires it; includes calling out in class or acting without considering the consequences
What was ADHD referred to after hyperkinesis?
hyperactive child syndrome as motor activity was then considered the main feature of ADHD
according to lecture which symptoms of the main three found in ADHD emerge first?
hyperactivity-impulsivity emerges before inattention
in the late 1950s what was ADHD referred to?
hyperkinesis which was attributed to the poor filtering of stimuli entering the brain
what can mimic the symptoms of ADHD?
illnesses, accidents, middle ear infections, mild seizures, chronic abuse, or stressful life events (i.e., a major move)
which categories do children and adolescents with ADHD consistently show deficits in?
in one or more executive functions, especially response inhibition, vigilance, working memory, and planning
what are the primary symptoms/key elements of ADHD?
inattentiveness (IA), and hyperactivity-impulsivity (HI)
what symptoms are girls with ADHD more likely to express?
inattentiveness/disorganization symptoms; they are also more likely to be hyperverbal then hyperactive
response-cost procedurres
involve the loss of privileges, activities, points, or tokens following inappropriate behavior, or brief periods of time-out; shown to be effective in reducing disruptive classroom behavior, and enhancing academic productivity
What is suggested about ADHD-PI compared to HI and C?
it has been suggested that ADHD-PI may be a completely separate disorder
what is the main problem in ADHD?
it seems to be one of controlling motor behavior
how was ADHD defined in the late 1970s?
it was argued that in addition to hyperactivity, deficits in attention and impulse control were also primary symptoms of ADHD; this helped define the DSM criteria
inattentive
lacking the ability to focus or sustain one's attention. children who are inattentive find it difficult to sustain mental effort during work or play and behave carelessly, as if they are not listening
what is the focus of stimulant medication
managing ADHD symptoms at school and home
what is the focus of parent management training?
managing disruptive child behavior at home, reducing parent-child conflict, and promoting prosocial and self-regulating behaviors
what is the focus of educational interventions?
managing disruptive classroom behavior, improving academic performance, teaching prosocial and regulating behaviors
what can raise the severity of ADHD symptoms?
marital conflict
what was ADHD referred to in the 1940s-1950s?
minimal brain damage and minimal brain dysfunction (MBD)
what do families with ADHD children report?
more mental health problems, greater parenting stress and less parenting competence, fewer contacts with extended family members, greater caregiver strain, less instrumental support, and slightly higher rates of marital conflict, separation, and divorce; increased alcohol consumption
stimulant medications
most studied, most effective, and most commonly used treatment for the management of symptoms of ADHD and its associated impairments
what is normally experienced by the parents of children with ADHD?
mothers = depression fathers = anti social behaviors (i.e., substance abuse)
of all of the factors towards ADHD which presents the strongest evidence?
neurobiological factors
in order to be diagnosed with ADHD does the child have to have both hyperactivity and inattention?
no they both don't need to be present, at least one does
what do children with ADHD work best on?
on self-paced tasks that they have chosen and on tasks that they find especially interesting that do not require them to sustain their attention
how can ADHD be identified in children? (not talking about symptoms)
only by characteristic patterns of behavior which vary quite a bit from child to child
who is primarily included in the ADHD-HI group?
preschoolers; may have limited value for older children
what are cognitive and behavioral impusivity predictors of?
problems with academic achievement, particularly in reading
impulsive
prone to acting with little or no consideration of possible consequences. this term is frequently used to describe children who suffer from ADHD
parent management training (PMT)
provides parents with a variety of skills to help them: - manage their child's oppositional and noncompliant behaviors - cope with the emotional demands of raising a child with ADHD - contain the problem so that it does not worsen - keep the problem from adversely affecting other family members
what do children with ADHD normally struggle with in school?
reading, spelling, and math
what side effects are there with stimulant medications?
reduced appetite, weight loss, slowing of expected gains in height and weight, increase in heart rate, and blood pressure, or problems falling asleep
cognitive impusivity
reflected in disorganization, hurried thinking, and the need for supervision
what does only behavioral impulsivity predict?
rule-breaking behavior and thus may be a specific sign of increased risk for conduct problems
what does a diagnosis of bipolar in young children do in regards to ADHD?
sharply increases the child's risk for previous or co-occuring ADHD; but the reverse isn't seen
what characterizes ADHD-PI?
slow cognitive processing speed; daydreamers; drowsy; spacy; in a fog; easily confused
what are the primary treatments of ADHD?
stimulant medication, parent management training, educational intervention
motor processes
such as allocation of effort, following prohibitive insturctions, response inhibition, and motor coordination and sequencing
emotional processes
such as self-regulation of arousal level, tolerating frustration, and mature moral reasoning
language processes
such as verbal fluency, communication, and the use of self0directed speech
cognitive processes
such as working memory, mental computation, planning and anticipation, flexibility of thinking and the use of organizational strategies
tic disorders
sudden, repetitive, nonrhythmic motor movements or sounds such as eye blinking, facial grimacing, throat clearing, and grunting; about 20% of children with ADHD also have this
what is the primary attentional deficit in ADHD?
sustained attention (i.e, persistence, vigilance)
who are more accurate raters of ADHD?
teachers more so then parents
selective attention
the ability to concentrate on relevant stimuli and not be distracted by noise in the environment (i.e., when studying for a test (relevant stimuli) how easily are you distracted by voices in a room?)
attentional capacity
the amount of information we can remember an attend to for a short time; children with ADHD are capable of remembering the same amount of information for a short time as other children
how do parents describe their infants who later were diagnosed with ADHD?
the baby had a difficult temperament -extremely active, unpredictable, over- or undersensitive to stimulation, and irritable with erratic sleep patterns and feeding patterns
of the three subcategories of ADHD which child is the most likely to be referred for treatment?
the child with ADHD-C
executive functions
the cognitive processes in the brain that activate, integrate, and manage other brain functions; they underlie a child's capacity for self-regulation, such as self-awareness, planning, self-monitoring, and self-evaluation
what suggests that children with ADHD may have trouble in alerting and preparation?
the fact that these children may show performance deficits from the very beginning of a task, not just a decrement over time
goodness of fit
the match between the child's earlier temperament and the parent's style of interaction
methylphenidate (ritalin)
the most commonly used drug for ADHD
According to lecture what is a major factor in exacerbating (making worse) versus ameliorating (reforming) a child's ADHD symptoms?
the quality of the parent/child relationship
what have studies shown in regards to diet, allergy, and lead as factors of ADHD?
there is little empirical support
why are children with ADHD constantly rejected by peers?
these children do not play by the same rules as others and don't seem to learn from past mistakes, despite their awareness of expected social behaviors and desire to conform to them; blunders appear more thoughtless than intentional
what do stimulant drugs do?
they alter activity in the frontostriatal region of the brain by affecting neurotransmitters (dopamine) which are important to this region
what have longitudinal studies found about the relationship of ADHD, CD, and ODD?
they have found the ADHD leads to CD and ODD
what intellectual deficits do children with ADHD tend to have?
they have trouble applying their intelligence to everyday life situations
What do children with ADHD-PI often have?
they often have a co-morbid disorder - an anxiety and/or mood disorder
when and how was ADHD first described?
they were first described in 1902, by George Still who believed that ADHD arose out of poor inhibitory volition and defective moral control
how may a child with an alerting affect respond to situations?
too quickely in situation requiring a slow and careful approach and too slowly in situations requiring a quick response
what sets children with hyperactivity-impulsivity apart from active children?
unlike other children with a high energy level children who have hyperactivity-impulsivity tend to accomplish very little (they aren't goal-directed)
sustained attention
vigilance; is the ability to maintain a persistent focus over time or when fatigued
what is the largest difference found in children with ADHD?
when a child with ADHD is in a situation that requires the child to inhibit motor activity you can see the most difference