Antibacterial and Anti-infective Agents

A patient is receiving gentamicin therapy: 100 mg intravenously at 0800, 1600, and 2400. At 0730, the nurse is informed that peak and trough levels needs to be drawn. When is the best time to obtain the peak level? 0800 0900 1600 2330

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While instructing a patient about antibiotic therapy, the nurse explains to the patient that bacterial resistance to antibiotics can occur when what happens? (Select all that apply.) A.) Patients stop taking an antibiotic after they feel better. B.) Environmental dispersion of antibiotic liquid occurs. C.) Antibiotics are prescribed according to culture and sensitivity reports. D.) Antibiotics are prescribed to treat a viral infection. E.) Antibiotics are taken with water or juice. F.) Antibiotics are taken with ascorbic acid (vitamin C).

A,B,D Not completing a full course of antibiotic therapy can allow bacteria that are not killed but have been exposed to the antibiotic to adapt their physiology to become resistant to that antibiotic. The same thing can occur when bacteria are exposed to antibiotics in the environment or when antibiotics are erroneously used to treat a viral infection.

The patient has been prescribed trimethoprim-sulfamethoxazole (Bactrim, Septra). The nurse notes that the patient has a history of kidney stones. What is the highest priority instruction for the nurse to give to the patient? A.) "Take the medication with a full glass of fluid." B.) "Take the medication at regularly spaced intervals." C.) "Take the medication on a full stomach." D.) "Take the medication on an empty stomach."

A.) "Take the medication with a full glass of fluid." Of the instructions provided, the only one that would affect the prevention of kidney stones is to take the medication with a full glass of fluid.

Amoxicillin (Amoxil) is prescribed for a patient who has a respiratory infection. The nurse is teaching the patient about this medication and realizes that more teaching is needed when the patient makes which statement? A.) "This medication should not be taken with food" B.) "I will take my entire prescription of this medication" C.) "I should report to my physician of any genital itching" D.) "If I experience any excess bleeding, I will contact the health care provider

A.) "This medication should not be taken with food"

A patient on antibiotic therapy needs trough levels drawn. Which is the most appropriate time for the nurse to draw the trough level? A.) 10 minutes before administration of the intravenous antibiotic B.) 30 minutes after beginning administration of the intravenous antibiotic C.) 60 minutes after completion of the intravenous antibiotic infusion D.) 90 minutes after the intravenous antibiotic is scheduled to be administered

A.) 10 minutes before administration of the intravenous antibiotic Trough levels are drawn just before infusion. Peak serum drug levels should be drawn 30 to 60 minutes after the medication is infused. The nurse should document the time drug administration is started and completed and the exact time a peak and/or trough level is drawn.

The nurse should question the prescription of tetracycline for which patient? A.) A 6-year old patient with Haemophilus influenzae B.) A 45-year-old patient with a history of diabetes mellitus C.) A 60-year-old patient with a history of hypertension D.) A 40-year-old patient diagnosed with rickettsiae

A.) A 6-year old patient with Haemophilus influenzae Tetracycline is contraindicated in children younger than 8 years because it can cause permanent discoloration of the teeth. Tetracycline is not contraindicated for patients diagnosed with diabetes mellitus or hypertension. Tetracycline is used to treat rickettsiae.

A patient with type 2 diabetes mellitus is started on co-trimoxazole (TMP-SMZ). Which nursing intervention is a priority for this patient? A.) Assess blood sugar. B.) Monitor platelet count. C.) Assess hemoglobin and hematocrit. D.) Take blood pressure every 4 hours.

A.) Assess blood sugar. Co-trimoxazole increases the hypoglycemic response when taken with sulfonylureas (oral hypoglycemic agents). The nurse should assess blood sugar and determine what oral hypoglycemic the patient is taking.

Penicillin G has been prescribed to a patient. Which nursing intervention(s) should the nurse perform for this patient? (Select all that apply). A.) Collect culture and sensitivity (C&S) before the first dose B.) Monitor the patient for mouth ulcers C.) Instruct the patient to to limit fluid intake to 1000mL/day D.) Have epinephrine on hand for potential severe allergic rxn E.) No particular interventions are required for this patient

A.) Collect culture and sensitivity (C&S) before the first dose B.) Monitor the patient for mouth ulcers D.) Have epinephrine on hand for potential severe allergic rxn

A patient is taking Sulfasalazine (Azulfidine). What should the nurse teach the patient to do? A.) Drink at least 10 glasses of fluid/day B.) Monitor blood glucose carefully to avoid hyper-glycemia C.) Avoid operating a motor vehicle, because this drug may cause drowsiness D.) Take this drug with an antacid to decrease the risk of GI distress

A.) Drink at least 10 glasses of fluid/day

Sulfasalazine (Azulfidine) has been ordered for a patient. The nurse knows that this drug is most effective against which organisms? A.) Escherichia coli & Clostridium B.) Neisseria gonorrhoeae and H. Influenzae C.) Pseudomonas aeruginosa and Heliobacter pylori D.) Enterococcus faecium and Staphylococcus aureus

A.) Escherichia coli & Clostridium

The nurse is caring for a patient who has been prescribed cefazolin sodium (Ancef). Which nursing assessment is the priority? A.) History, including allergies B.) Cardiac assessment C.) Neurological assessment D.) History of immunizations

A.) History, including allergies Antibiotic allergy is one of the most common drug allergies. These allergies also have the potential to cause severe anaphylaxis and death and, therefore, have more importance than the other assessments listed.

A patient has been ordered telithromycin (Ketek) as well as simvastatin (Zocor). What is the nurse's best action? A.) Hold the medication and call the health care provider. B.) Administer the medications as prescribed. C.) Separate the medications by 6 hours. D.) Have the patient take the medications with food or milk.

A.) Hold the medication and call the health care provider. Telithromycin should not be taken with simvastatin owing to the risk of serious side effects. Separating the medications by 6 hours or taking the medication with milk or food will not lessen the risk of side effects. The nurse should not administer these medications.

A patient is taking azithromycin (Zithromax). Which nursing interventions would the nurse plan to implement for this patient? (Select all that apply). A.) Monitor periodic liver function tests B.) Dilute w/ 50mL of D5W for IV administration C.) Instruct patient to report any hearing loss D.) Instruct the patient to report any sign of superinfection E.) Teach the patient to take oral drug 1 hour before a.c. or 2 hours p.c. F.) Advise the patient to avoid antacids from 2 hours prior to 2 hours after administration

A.) Monitor periodic liver function tests C.) Instruct patient to report any hearing loss D.) Instruct the patient to report any sign of superinfection E.) Teach the patient to take oral drug 1 hour before a.c. or 2 hours p.c. F.) Advise the patient to avoid antacids from 2 hours prior to 2 hours after administration

A patient is taking cefoperazone (Cefobid). The nurse anticipates which appropriate nursing intervention(s) for this medication? (Select all that apply). A.) Monitoring renal function studies B.) Monitoring liver function studies C.) Infusing IV medication over 30 minutes D.) Monitoring the patient for mouth ulcers E.) Advising the patient to take the medication with food

A.) Monitoring renal function studies B.) Monitoring liver function studies C.) Infusing IV medication over 30 minutes D.) Monitoring the patient for mouth ulcers

A patient who is being treated for a neuromuscular disease has been ordered telithromycin (Ketek). What is the nurse's highest priority action? A.) Notify the health care provider. B.) Administer the first dose promptly. C.) Notify the pharmacy. D.) Administer the medication with food.

A.) Notify the health care provider. Use of telithromycin (Ketek) can worsen symptoms of myasthenia gravis. The health care provider should be notified.

Which nursing intervention(s) should the nurse consider for the patient taking ciprofloxacin (Cipro)? (Select all that apply). A.) Obtain culture before drug administration B.) Tell patient to avoid taking Cipro w/ antacids C.) Monitor patient for tinnitus D.) Encourage fluids to prevent crystalluria E.) Infuse IV Cipro over 60 minutes F.) Monitor blood glucose, because Cipro can decrease effects of oral hypoglycemic

A.) Obtain culture before drug administration B.) Tell patient to avoid taking Cipro w/ antacids C.) Monitor patient for tinnitus D.) Encourage fluids to prevent crystalluria E.) Infuse IV Cipro over 60 minutes

Which instructions will the nurse include when teaching a patient about gentamicin? (Select all that apply). A.) Patient should report any hearing loss B.) Patient should use sunscreen C.) IV gentamicin will be given over 20 minutes D.) Patient will be monitored for mouth sores and vaginitis E.) Peak levels will be drawn 30 mins before IV dose F.) Patient should increase fluid intake

A.) Patient should report any hearing loss B.) Patient should use sunscreen D.) Patient will be monitored for mouth sores and vaginitis F.) Patient should increase fluid intake

The nurse is teaching a patient about trimethoprim-sulfamethoxazole (Bactrim). Which instructions will the nurse plan to include? (Select all that apply). A.) Report any bleeding or bruising B.) Report any diarrheas or bloody stools C.) Report any fever, rash, or sore throat D.) Avoid unprotected exposure to sunlight. E.) Report thirst and polyuria

A.) Report any bleeding or bruising B.) Report any diarrheas or bloody stools C.) Report any fever, rash, or sore throat D.) Avoid unprotected exposure to sunlight.

A patient is prescribed cephradine (Velosef). Which actions should the nurse implement? (Select all that apply). A.) Report seizures to health care provider B.) Advise the patient to eat yogurt to prevent superinfection C.) Monitor the patient for severe allergic rxn, especially after the 1st and 2nd dose D.) Advise patient to take on an empty stomach, even if GI distress occurs E.) Culture the infected area before administering the first dose

A.) Report seizures to health care provider B.) Advise the patient to eat yogurt to prevent superinfection C.) Monitor the patient for severe allergic rxn, especially after the 1st and 2nd dose

The nurse enters the patients room to find that his HR is 120, BP 70/50, and has red blotching on his face and neck. Vancomycin (Vancocin) is running IVBP. The nurse believes that this patient is experiencing a severe adverse effect called "red man syndrome". What action will the nurse take? A.) Stop the infusion and call the laboratory B.) Reduce the infusion to 10mg/min C.) Encourage the patient to drink more oral fluids up to 2L/day D.) Report onset of Stevens-Johnson syndrome to the health care provider.

A.) Stop the infusion and call the laboratory

A patient is receiving tetracycline (Vibramycin). Which advice should the nurse include when teaching this patient about tetracycline? A.) Take sunscreen precautions at the beach B.) Take an antacid w/ the drug to minimize GI distress C.) Obtain frequent hearing tests for early detection of hearing loss D.) Obtain frequent eye exams for early detection for retinal damage

A.) Take sunscreen precautions at the beach

A patient is taking piperacillin-tazobactam (Zosyn). Which nursing interventions are most appropriate for this drug? (Select all that apply.) Give with an aminoglycoside. Send specimen to lab for C&S before antibiotic therapy is started. Instruct patient to take entire prescribed drug. Instruct patient to restrict fluid intake. Monitor for symptoms of superinfection, including stomatitis and vaginitis.

ANSWER B, C, E

The nurse is administering vancomycin to a patient. Which nursing interventions are appropriate? Monitor the patient for _______. (Select all that apply.) A.) adequate hearing B.) appropriate IV rate C.) pseudomembranous colitis D.) Stevens-Johnson syndrome E.) hypotension and tachycardia F.) redness of the face, neck, and chest

Answer : A, B, D, E, F

A patient is prescribed trimethoprim-sulfamethoxazole (Bactrim) to treat a urinary tract infection. Which of the following statements made by the patient indicate that teaching was effective? A. "It is safe to take this medication if I become pregnant." B. "I will drink at least 8 to 10 glasses of water every day." C. "I will be able to stop this medication when I'm symptom free." D. "I may have increased blood sugar while taking this medication."

Answer: B Rationale: Sulfamethoxazole may cause crystalluria unless adequate hydration is maintained.

A patient is prescribed vancomycin (Vancocin) orally for antibiotic-associated pseudomembranous colitis. The nurse will monitor the patient for: A. leukopenia. B. red person syndrome. C. liver impairment. D. ototoxicity.

Answer: D Rationale: The most serious adverse effect of vancomycin is ototoxicity. Red person syndrome occurs only with rapid intravenous administration. Thrombocytopenia is an adverse effect of vancomycin

A patient with a history of a severe anaphylactic reaction to penicillin has an order to receive cephalosporin. The nurse should: A. administer the cephalosporin as ordered. B. contact the healthcare provider for a different antibiotic. C. administer a test dose of cephalosporin to determine reactivity. D. have an epinephrine dose available when administering the cephalosporin.

B Rationale: If reactions to penicillin have been severe, cephalosporins should not be administered.

The patient has been ordered azithromycin (Zithromax) and asks the nurse why the medication does not have to be taken as often as other antibiotics that have previously been ordered. What is the nurse's best response? A.) "I'll call the pharmacy and ask about the chemical makeup of the drug." B.) "This drug has a longer duration of action than some of the other antibiotics." C.) "You'll need to ask your health care provider questions like that." D.) "This is a much more effective drug than what you received previously."

B.) "This drug has a longer duration of action than some of the other antibiotics." Azithromycin (Zithromax) is one of the newer macrolide antibiotics. It has a longer duration of action as well as fewer and less severe gastrointestinal side effects than erythromycin.

A patient prescribed azithromycin (Zithromax) expresses concern regarding gastrointestinal upset experienced when taking erythromycin. What will the nurse tell this patient? A.) "I will call the doctor and ask for a different antibiotic." B.) "This drug is like erythromycin but has less severe gastrointestinal side effects." C.) "You need this medication and will have to tolerate the nausea." D.) "I will ask the doctor for a prescription for an antiemetic for possible nausea."

B.) "This drug is like erythromycin but has less severe gastrointestinal side effects." Azithromycin (Zithromax) is one of the newer macrolide antibiotics. It has a longer duration of action as well as fewer and less severe gastrointestinal side effects than erythromycin.

Which instruction will the nurse include in the discharge teaching for a patient receiving tetracycline? A.) "Take the medication until you feel better." B.) "Use sunscreen and protective clothing when outdoors." C.) "Keep the remainder of the medication in case of recurrence." D.) "Take the medication with food or milk to minimize gastrointestinal upset."

B.) "Use sunscreen and protective clothing when outdoors." Photosensitivity is a common side effect of tetracycline. Exposure to the sun can cause severe burns. The medication should not be taken with milk and should be completely finished.

A 22-year-old female patient is put on amoxicillin. Which is the most important intervention for this patient? A.) Instruct the patient to not take the medication before meals. B.) Assess if the patient is on oral contraceptives. C.) Inform the patient about possible superinfections. D.) Assess the patient for cross sensitivity.

B.) Assess if the patient is on oral contraceptives. This medication may decrease the effectiveness of oral contraceptives. The nurse needs to assess whether or not the patient is on oral contraceptives and whether or not the patient is sexually active.

A patient has been on sulfonamides for urinary tract infections. The nurse assesses the patient and finds bruises on the legs and arms. What is the nurse's best action? A.) Ask the patient if someone is abusing her. B.) Assess the patient's platelet counts. C.) Tell the patient to be more careful. D.) Administer vitamin K to the patient.

B.) Assess the patient's platelet counts. Blood disorders such as hemolytic anemia, aplastic anemia, and low white blood cell and platelet counts could result from prolonged use and high dosages. The nurse should assess the patient before assuming vitamin K deficiency, potential abuse, or frequent falls.

The patient has been started on a medication regimen that includes trimethoprim-sulfamethoxazole (Bactrim). The nurse notes that the source of the patient's infection has been determined to be viral in origin. What is the nurse's highest priority action? A.) Administer the medication as ordered by the provider. B.) Contact the health care provider to discuss the medication. C.) Ask the patient if he knows how he contacted the infection. D.) Ensure that the information is documented in the chart.

B.) Contact the health care provider to discuss the medication. The health care provider should be contacted regarding the ordering of Bactrim for this patient since it has not been shown to be effective in treating viral infections.

A patient is admitted to the health care facility with methicillin-resistant Staphylococcus aureus (MRSA). The nurse anticipates administration of which drug? A.) Nafcillin (Nallpen) B.) Vancomycin (Vancocin) C.) Aztreonam (Azactam) D.) Piperacillin-tazobactam (Zosyn)

B.) Vancomycin (Vancocin)

A patient is taking sulfonamide for an acute UTI. Which medication does the nurse recognize as a short-acting sulfonamide? A.) sulfasalazine (Azulfidine) B.) sulfadiazine (Microsulfon) C.) sulfamethoxazole (Gantanol) D.) co-trimoxazole/TMP-SMZ (Bactrim)

B.) sulfadiazine (Microsulfon)

Which statement by a patient who has received teaching on tetracycline therapy indicates that more teaching is indicated? A.) "I will store the medication away from light and extreme heat." B.) "I will use an additional contraceptive technique because this drug may cause the oral contraceptive I take to be less effective." C.) "I will take this medication with an antacid." D.) "If my stomach becomes upset when taking this medication, I will take it with nondairy foods."

C.) "I will take this medication with an antacid."

The patient has been prescribed trimethoprim-sulfamethoxazole (Bactrim, Septra). The patient complains of experiencing abdominal cramping. What is the highest priority instruction for the nurse to give to the patient? A.) "Take the medication with a full glass of fluid." B.) "Take the medication at regularly spaced intervals." C.) "Take the medication with food or milk." D.) "Take the medication on an empty stomach."

C.) "Take the medication with food or milk." Administering the medication with food or milk may minimize the existence of abdominal cramping. The other interventions may be helpful but will not necessarily prevent abdominal cramping.

The nurse is teaching a patient about sulfadiazine (Micro-sulfon). Which instructions will the nurse include in teaching? A.) Avoid caffeine during sulfonamide treatment B.) Administer in 50 mL of fluid over 30 minutes C.) Avoid sulfonamides during the third trimester of pregnancy D.) Use an ultraviolet light to enhance drug effectiveness

C.) Avoid sulfonamides during the third trimester of pregnancy

Oral trimethoprim-sulfamethoxazole (Bactrim, Septra) is prescribed for the patient and is being administered four times a day. What is the nurse's best action? A.) Schedule the medication before meals and at bedtime. B.) Instruct the patient about potential ringing in the ears. C.) Call the health care provider. D.) Instruct the patient not to drink milk with the medication.

C.) Call the health care provider. The half-life of this drug is 8 to 12 hours, and the patient should receive it twice a day. The nurse should call the health care provider to clarify this order. The medication should not be scheduled four times a day, is not expected to cause ototoxicity, and should not have an interaction with milk.

The patient has been ordered lincomycin (Lincocin). The patient reports to the nurse that the patient has experienced reduced renal function in the past. The nurse anticipates that the health care provider will take which action? A.) Place the medication on hold until renal function improves. B.) Increase the original dosage of the medication. C.) Decrease the original dosage of the medication. D.) Continue with the medication as originally ordered.

C.) Decrease the original dosage of the medication. Rather than place the medication on hold because of the patient's decreased renal function, the health care provider will likely opt to decrease the originally ordered dosage to accommodate the change in function.

The patient has been diagnosed with Legionnaires' disease. Which drug does the nurse anticipate the provider will order? A.) Daptomycin (Cubicin) B.) Lincomycin (Lincocin) C.) Erythromycin (E-Mycin) D.) Azithromycin (Zithromax)

C.) Erythromycin (E-Mycin) The drug of choice for treatment of Legionnaires' disease is erythromycin (E-Mycin).

When planning care for a patient receiving a sulfonamide antibiotic, which is a primary intervention? A.) Encourage liquids that produce acidic urine. B.) Encourage a diet that causes an alkaline ash. C.) Force fluids to at least 2000 mL/day. D.) Insert a Foley catheter for accurate input and output measurement.

C.) Force fluids to at least 2000 mL/day. Forcing fluids will help prevent crystallization in the urine and kidney stone formation associated with sulfonamide antibiotics, regardless of the type of fluid consumed. It is outside the nurse's scope of practice to decide to insert a Foley catheter. Consuming a specific type of diet will not decrease the risk of crystallization.

The patient taking intravenous gentamicin (Garamycin) has elevated blood urea nitrogen (BUN). What is the nurse's best course of action? A.) Have the patient increase fluid intake. B.) Monitor peak and trough levels. C.) Hold the medication. D.) Insert a Foley catheter.

C.) Hold the medication. Gentamicin (Garamycin) has a high potential for nephrotoxicity and is thus contraindicated in patients with elevated renal function tests such as BUN and creatinine. The nurse should hold the medication and call the health care provider. Increasing fluids will not decrease the patient's BUN.

A patient is receiving amoxicillin (Amoxil). The nurse understands that the action of this drug is by which process. A.) Inhibition of protein synthesis B.) Alteration of membrane permeability C.) Inhibition of bacterial wall synthesis D.) Alteration of bacterial ribonucleic acid synthesis

C.) Inhibition of bacterial wall synthesis

The nurse is caring for a patient who is being treated for acne. The nurse anticipates that the health care provider is most likely to treat the patient using which medication? A.) Polymyxin B.) Bacitracin C.) Tetracycline D.) Vancomycin

C.) Tetracycline Tetracycline is considered to be a drug of choice for the treatment of acne rather than the other medications listed.

The nurse is caring for multiple patients receiving antibiotics. Which patient will the nurse assess first? A.) The patient who just started azithromycin therapy with a fever B.) The patient who is taking clindamycin (Cleocin) and has gastric upset C.) The patient who is taking vancomycin (Vancocin) with furosemide (Lasix) D.) The patient who is taking telithromycin (Ketek) and is 18 years old

C.) The patient who is taking vancomycin (Vancocin) with furosemide (Lasix) The risk of ototoxicity with vancomycin is increased for patients taking furosemide. The nurse should assess this patient first. A patient who has started antibiotic therapy would be expected to have a fever. Gastric upset is common with this antibiotic. Telithromycin is recommended for patients 18 years and older.

A patient enters the emergency department with a draining wound. Once the patient is admitted and assessed, the priority nursing intervention is to A.) administer the ordered antibiotics. B.) teach the patient about the ordered antibiotics. C.) culture the wound. D.) enforce droplet isolation precautions.

C.) culture the wound.

Trimethoprim-sulfamethoxazole (Bactrim) is prescribed for the client. The nurse tells the client to report which of the following symptoms if it develops during the course of this medication therapy? A. nausea B. diarrhea C. headache D. sore throat

D. sore throat Clients taking Bactrim, should be informed about early signs of blood disorders that can occur from this medication. Signs include sore throat, fever, or pallor

Which statement will the nurse include when teaching a patient about cephalosporin therapy? A.) "Avoid ingesting buttermilk or yogurt when taking this medication." B.) "Stop taking the medication when you feel better." C.) "Immediately stop taking the medication if you develop nausea." D.) "Inform your health care provider if you develop mouth ulcers."

D.) "Inform your health care provider if you develop mouth ulcers."

A patient is taking levofloxacin (Levaquin). What does the nurse know to be true regarding this drug? A.) Administer IV only B.) May cause HTN C.) Classified as aminoglycoside D.) An adverse effect is dysrhythmia

D.) An adverse effect is dysrhythmia

A Patient is prescribed dicloxacillin. (Dynapen). For which adverse effect should the nurse monitor the patient? A.) Constipation B.) Renal failure C.) Hypertension D.) Hemolytic anemia

D.) Hemolytic anemia

A patient has been prescribed trimethoprim-sulfamethoxazole (Bactrim, Septra). What is the nurse's primary intervention for this patient? A.) Instruct the patient to take the medication for 14 days. B.) Ensure the patient eats something when taking the medication. C.) Assess the patient's urine before and after treatment. D.) Instruct the patient to increase fluids in the diet.

D.) Instruct the patient to increase fluids in the diet. Increased fluid intake is highly recommended to avoid complications such as crystallization in the urine. The course of therapy is not always 14 days; the patient does not have to take the drug on a full stomach, and the drug is not prescribed only for urinary tract infections.

A patient has been perscribed amoxicillin (Amoxil). What does the nurse know is true about this medication? A.) It has a normal adult dose of 2 grams q6h. B.) It has a common side effect of hypotension C.) It has an intramuscular administration route D.) It is used to treat respiratory infections

D.) It is used to treat respiratory infections

For which serious side effect should the nurse monitor a patient who is taking lincosamides? A.) Seizures B.) Ototoxicity C.) Hepatotoxicity D.) Pseudomembranous colitis

D.) Pseudomembranous colitis

A patient is ordered to take trimethoprim-sulfamethoxazole (Bactrim). The nurse knows to be aware of which adverse effect? A.) Bronchospasm B.) Dysrhythmias C.) Pseudomembranous colitis D.) Stevens-Johnson syndrome

D.) Stevens-Johnson syndrome

The patient has been diagnosed with ulcerative colitis. The nurse recognizes that which medication may be ordered to treat this condition? A.) Cephazolin (Ancef) B.) Sulfadiazine (Microsulfon) C.) Trimethoprim-sulfamethoxazole (Bactrim) D.) Sulfasalazine (Azulfidine)

D.) Sulfasalazine (Azulfidine) Sulfasalazine (Azulfidine) is a drug of choice for treatment of ulcerative colitis.

When instructing a patient about antibiotic therapy, the nurse explains that which condition occurs when the normal flora are disturbed during antibiotic therapy? A.) Hypersensitivity B.) Rebound toxicity C.) Organ toxicity D.) Superinfection

D.) Superinfection Antibiotic therapy can destroy the normal flora of the body, which typically inhibit the overgrowth of fungi and yeast. When the normal flora are decreased, these organisms can overgrow and cause infections.