Blood (Chapter 17)
Over ____________ dissolved solutes in blood
100
Globin
4 polypeptide chains
Albumin
60% of plasma proteins
What percentage of body weight does blood make
8%
When neither anti-A serum nor anti-B serum cause clumping of donor cells, the blood type is: A. O B. B C. AB D. A
A
Which of the choices below is the parent cell for all formed elements of blood? A. Hemocytoblast B. Polymorphonuclear cell C. Megakaryocyte D. Normoblast
A
A person who lacks agglutinogen A, but has agglutinogen B would have blood type: A. O B. B C. AB D. A
B
Universal donor blood type A. AB B. O C. B D. A
B
What is the average normal pH range of blood? A. 4.65-4.75 B. 7.35-7.45 C. 7.75-7.85 D. 8.35-8.45
B
Which granulated leukocyte is most likely to be active during a bacterial infection? A. Basophils B. Neutrophils C. Monocytes D. Lymphocytes
B
Which leukocyte might you expect to find in higher quantities in a person experiencing allergies? A. Neutrophil B. Eosinophil C. Lymphocyte D. Basophil
B
Hemostasis is important for: A. RBC production B. WBC production C. Stoppage of bleeding D. RBC recycling
C
Which of the following would NOT lead to a bleeding disorder? A. Thrombocytopenia B. Impaired liver function C. Excess calcium in diet D. Vitamin K deficiency
C
Which two factors below make rapid and substantial blood loss life threatening? A. Loss of immunity, carbon dioxide carrying capacity B. Loss of immunity, BP C. Loss of BP, oxygen carrying capacity D. Loss of clotting ability, osmotic pressure
C
With a patient that is administered an injection of erythropoietin (EPO) you would expect to see: A. Increased WBC count B. Decreased hematocrit C. Increased hematocrit D. Decreased WBC count
C
Which ABO blood type is considered to be the universal recipient? A. A B. O C. B D. AB
D
formed elements (3)
Erythrocytes (RBC) Leukocytes (WBC) Platelets
Hemocytoblast
Give rise to all formed elements
Genesis of platelets Hannah Montana put macarony plate
Hemocytoblast Megakaryoblast Promegakaryocyte Megakarycyte Platelets
Erythropoiesis
Hemocytoblast Proerythroblast Early erythroblast Late erythroblast Normoblast (2) Reticulocyte Erythrocyte
Agranulocytes (2)
Lymphocytes Monocytes
Granulocytes (3)
Neutrophils (infection) Eosinophils (inflammation) Basophils
How does blood color vary
O2 content
Erythrocyte characteristics (3)
Small diameter Biconcave/anucleate/no organelles Filled w/ hemoglobin (Hb) for gas transport
Centrifuged blood consists of 3 layers
Top: plasma (55%) Buffy coat (<1%): WBC's/platelets Bottom: erythrocytes (45%)
All lymphocytes are leukocytes, but not all leukocytes are lymphocytes. T/F?
True
Blood is the only fluid tissue in the body. T/F?
True
Leukopenia is an abnormally low number of leukocytes. T/F?
True
Mature erythrocytes lack a nucleus. T/F?
True
Hemostasis Events (3)
Vascular spasm (vasoconstriction) Platelet plug formation Coagulation (form clot)
Diapedesis
WBC leave capillaries
Amoeboid Motion/Positive chemotaxis
WBC move through tissue spaces
Hemoglobin (Hb)
binds reversibly w/ oxygen red heme bound to protein globin
WBC function
defense against disease
Hematopoiesis
formation of all blood cells
Bone marrow is where ____________ takes place
hematopoiesis
Hemocytoblasts or
hematopoietic stem cells
formed elements
living blood cells
plasma
nonliving fluid
Hematocrit
percent of blood volume that is RBC's Norms F: 42% M: 47%
